Neural Influence on Cancer, Tumor Microenvironment and Cancer Immunology (J2)
January 18-21, 2025  | Fairmont Banff Springs, Banff, AB, Canada
Brian M. Davis, Michelle Monje and Ihsan Ekin Demir
Scholarship Deadline: Oct. 22, 2024 | Abstract Deadline: Oct. 22, 2024 | Early Registration Deadline: Dec. 3, 2024
This meeting will feature a Career Roundtable where trainees and early-career investigators will have the opportunity to interact with field leaders from across academic and industry sectors for essential career development advice and networking opportunities.
* Session Chair † Invited but not yet accepted | Program current as of May 30, 2024 | For the most up-to-date details, visit https://www.keystonesymposia.org
Saturday, January 18, 2025
Registration (4:00–8:00 PM)
Welcome Mixer (6:00–8:00 PM)
Sunday, January 19, 2025
Welcome and Keynote Address (8:00–9:00 AM)
Michelle Monje, Stanford University
Neuronal Activity Drives Glioma Growth and Initiation through both Paracrine and Synaptic Signaling
Neuron-Cancer Chemical and Paracrine Signaling (9:00–11:15 AM)
Shawn Hervey-Jumper, University of California, San Francisco
Glioblastoma Remodels Functional Neural Circuits
Ihsan Ekin Demir, Technische Universität München
Neuronal Glutamate Signaling and Progression of Pancreatic Cancer
David H. Gutmann, Washington University School of Medicine
Neuronal Hyperexcitability Drives Central and Peripheral Nervous System Tumor Progression in Models of Neurofibromatosis-1
Workshop 1: Late-breaking research presentations selected from abstract submissions (2:30–4:30 PM)
Coffee Available (4:30–5:00 PM)
Neuronal Influence on Cancer Initiation and Growth (5:00–7:00 PM)
Jeremy Borniger, Cold Spring Harbor Laboratory
A Central Mechanism Driving Aberrant HPA-Axis Function in Breast Cancer
Karen Dixon, University of Basel
Talk Title to be Announced
Moran Amit, University of Texas MD Anderson Cancer Center
Cancer Associated Neurogenesis and its Impact on Response to Therapy
Posters (7:30–10:00 PM)
Monday, January 20, 2025
Defining and Shaping the Metastatic Microenvironment (Joint) (8:00–11:00 AM)
Michael Angelo, Stanford University
Talk Title to be Announced
Peter C. Scacheri, Amgen Research
Dynamic Changes in Chromatin Accessibility During Osteosarcoma Lung Metastasis Expose Vulnerabilities
David Lyden, Weill Cornell Medical College
Tumor Induced Liver Metabolic Dysfunction Drives Metastasis
Mikala Egeblad, Cold Spring Harbor Laboratory
Immune Control and Escape at the Metastatic Site
Career Roundtable (Joint) (3:00–4:30 PM)
Coffee Available (4:30–5:00 PM)
The Brain-Body Axis in Metastasis (Joint) (5:00–7:00 PM)
Humsa Venkatesh, Brigham and Women's Hospital
Neuronal-Activity Dependent Mechanisms of Small Cell Lung Cancer Progression
Manuel Valiente, Spanish National Cancer Research Centre
Strategies to Challenge Brain Metastasis Lethality in Mice and Human/The Effects of Brain Metastasis on Neural Circuits
Erica Sloan, Monash University
Blocking Stress Signaling to Control Metastatic Breast Cancer
Posters (7:30–10:00 PM)
Tuesday, January 21, 2025
Nervous System Effects on the Immune System and Immuno-Oncology (8:00–11:00 AM)
Sébastien Talbot, Queen’s University
Tumor-Infiltrating B Cells tune Nociceptor Neurons Immunomodulation
Lauren Abrey,  InCephalo Therapeutics
Talk Title to be Announced
Nicole Scheff, University of Pittsburgh
Sympathetic and Sensory Nerve Coupling Modulates Cancer Immunosurveillance and Growth
Elizabeth A. Repasky, Roswell Park Cancer Institute
Beta Adrenergic Receptors as a Targetable Checkpoint for Reducing Immune Suppression in the Tumor Microenvironment
Workshop 2: Late-breaking research presentations selected from abstract submissions (2:30–4:30 PM)
Coffee Available (4:30–5:00 PM)
Nervous System Effects on Cancer Invasion and Metastasis (5:00–6:45 PM)
Frank Winkler, University Hospital Heidelberg
Neuronal Influence on Glioma Invasion and Brain Metastasis
Richard J. Wong, Memorial Sloan Kettering Cancer Center
Mechanisms of Perineural Invasion
Nisha J. D'Silva, University of Michigan School of Dentistry
Neural Phenotypes in Cancer Progression
Meeting Wrap-Up: Outcomes and Future Directions (Organizers) (6:45–7:00 PM)
Entertainment (8:00–11:00 PM)
Wednesday, January 22, 2025
Departure (12:00–11:59 PM)