This meeting took place in 2004

For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Lymphocyte Activation and Signaling (A3)

Organizer(s) Susan K. Pierce and Gary A. Koretzky
January 8—13, 2004
Sheraton Steamboat Resort • Steamboat Springs, Colorado USA
Abstract Deadline: Sep 16, 2003
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Nov 10, 2003

Sponsored by Berlex Biosciences and the Director's Sponsor Fund

Summary of Meeting:
The cells of the immune system are armed with a dizzying array of signaling receptors requiring them to integrate an enormous amount of information about their environment to mount the appropriate biologic response. Over the last several years much has been learned about the biochemical nature of the signaling cascades initiated by interactions of individual receptors with their ligands. Indeed, for many immune cell receptors the second messenger pathways have been described in exquisite detail and have been the focus of several national and international meetings. This progress presents an exciting new challenge, namely, to understand how multiple signals are integrated in the context of the entire cell to bring about the ultimate cellular response. Frameworks for understanding signaling at the level of the whole cell have been provided by important new concepts emerging in both cell and molecular biology. These concern the spatial organization of signaling receptors, the integration of signals emanating for multiple receptors and the influence of such signals on gene expression. Significantly, much of the recently gained knowledge of immune cell signaling is having a direct impact on important clinical areas including: autoimmunity, immunodeficiency, vaccines, tumor immunity, transplantation and infectious diseases. Distinguished scientists working at the cutting edge of immune cell signaling will describe their new findings and address how these issues relate to human disease. Speakers will describe the spatial organization of immune cell receptors in the plasma membrane and interactions of receptors with the cytoskeleton and molecular adaptors. The molecular nature of the integration of signals will be described for both the adaptive immune system’s antigen receptors and coreceptors as well as the innate system’s receptors. How the integrated signals ultimately affect chromatin structure and gene regulation will be described. Signaling will also be discussed in the global processes of chemotaxis, homeostasis, response to viral infection, apoptosis and immune deficiencies. Lastly, the next frontier--visualizing signaling in vivo--will be addressed. The proposed meeting will provide a view of how the initial encounter of immune cell signaling receptor with their ligands ultimately leads to the biological response be it activation, differentiation, movement, or cell death and how this knowledge is being translated to important clinical problems.

View Meeting Program


Scholarship / Award Information

Scholarship Deadline: (11:59 PM US Mountain Standard Time)
*All deadlines end at 11:59 PM US Mountain Standard Time
NOTE: Please use the button above to Apply for a Scholarship


Keystone Symposia is offering scholarships of up to 1,200 USD to Students and Postdoctoral fellows. These scholarships are to be used to help defray the expenses associated with conference attendance, including airfare (restrictions may apply based on funding source), ground transportation, lodging costs, and a portion of meeting registration. Receipts will be required to receive reimbursement.

Abstracts submitted for poster presentation will be used as the basis for awarding the scholarships. Scholarship recipients will be selected based on the quality of science of the abstract and the relevance of the abstract to the conference topic. Only one application per abstract is accepted. Only one award per lab will be allocated.


To be eligible for a scholarship, you must be:

A graduate student or postdoctoral fellow currently enrolled in an academic institute at the start of the meeting for which you are applying. Note: a graduate student is defined as a student who is studying for a higher degree at an academic institution. A postdoctoral fellow is defined as an individual with a Ph.D., M.D., or DVM degree who is engaged in a temporary period of mentored research and/or scholarly training for the purpose of acquiring the professional skills needed to pursue their desired career path, and is within 6 years of these degrees.

Review Criteria

Criteria for Abstract Review:

  1. Relevance to the meeting topic
  2. Significance of the scientific question and results
  3. Style
    • Organization (e.g. the abstract has a clear beginning, middle and end)
    • Grammar and spelling
  4. Clarity of scientific presentations
    • Clear question or hypothesis
    • Sufficient background
    • The experimental approach and rationale for the approach are clear
    • The results are clearly presented
    • The interpretation and conclusions are reasonable and logical

Application Process

If you are eligible and wish to be considered for a scholarship, you should complete all of the following by the scholarship deadline for the meeting you wish to attend. It is recommended you begin these steps in advance of the deadline date to ensure completion.

Click here to start a scholarship application.

  See the Scholarship FAQ's

Underrepresented Trainee Scholarships are also available...
Please Click Here for more information about Underrepresented Trainee Scholarship.

  See the Underrepresented Trainee Scholarship FAQ's

If you have any questions, please contact