This meeting took place in 2005

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Hormonal Regulation of Tumorigenesis (B6)

Organizer(s) Nancy L. Weigel, Suzanne A. Fuqua and Donald Tindall
February 20—25, 2005
Hyatt Regency Monterey • Monterey, California USA
Abstract Deadline: Oct 20, 2004
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Dec 20, 2004

Supported by The Director's Fund

Summary of Meeting:
Steroid hormones are key factors in the development and growth of tumors in hormone dependent tissues including breast and prostate. These cancers are not only two of the most prevalent cancers, but are also second only to lung cancer in deaths from cancer. Thus, there is a great deal of interest in developing methods to block the actions/production of the steroids. The actions of the steroids are mediated by steroid hormone receptors, members of the nuclear receptor family of ligand-activated transcription factors. However, recent and ongoing studies have shown that the type and magnitude of the activities of the receptors is dependent upon the cohort of coactivators, corepressors, and activity of cell signaling pathways in the cell; these factors and their interaction with receptors are potential therapeutic targets. In both breast and prostate cancer, hormone ablation, or anti-hormone therapies are commonly used. However, tumors become resistant to these treatments. Although, it was initially assumed that these tumors had bypassed the requirements for the steroid receptors, there is exciting new data coming from a number of labs indicating that these tumors remain receptor-dependent and that alterations in receptor expression, coregulator expression and/or cell signaling permit the receptors to continue to function. Thus, there is evidence that androgen receptor is activated in tumors that have become resistant to androgen ablation and that some tamoxifen resistant tumors retain estrogen receptor dependence. Consequently, the contribution of steroid receptor action in hormonally regulated tumors is greater than initially realized and raises a new set of questions regarding how to block the receptor activity. The goal of this meeting is to bring together experts in steroid hormone action with experts in hormonal effects in tumorigenesis to address the important questions of the mechanisms by which the hormones and their receptors induce growth of tumors and how these processes can be blocked.

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Scholarship / Award Information

Scholarship Deadline: (11:59 PM US Mountain Standard Time)
*All deadlines end at 11:59 PM US Mountain Standard Time
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Keystone Symposia is offering scholarships of up to 1,200 USD to Students and Postdoctoral fellows. These scholarships are to be used to help defray the expenses associated with conference attendance, including airfare (restrictions may apply based on funding source), ground transportation, lodging costs, and a portion of meeting registration. Receipts will be required to receive reimbursement.

Abstracts submitted for poster presentation will be used as the basis for awarding the scholarships. Scholarship recipients will be selected based on the quality of science of the abstract and the relevance of the abstract to the conference topic. Only one application per abstract is accepted. Only one award per lab will be allocated.


To be eligible for a scholarship, you must be:

A graduate student or postdoctoral fellow currently enrolled in an academic institute at the start of the meeting for which you are applying. Note: a graduate student is defined as a student who is studying for a higher degree at an academic institution. A postdoctoral fellow is defined as an individual with a Ph.D., M.D., or DVM degree who is engaged in a temporary period of mentored research and/or scholarly training for the purpose of acquiring the professional skills needed to pursue their desired career path, and is within 6 years of these degrees.

Review Criteria

Criteria for Abstract Review:

  1. Relevance to the meeting topic
  2. Significance of the scientific question and results
  3. Style
    • Organization (e.g. the abstract has a clear beginning, middle and end)
    • Grammar and spelling
  4. Clarity of scientific presentations
    • Clear question or hypothesis
    • Sufficient background
    • The experimental approach and rationale for the approach are clear
    • The results are clearly presented
    • The interpretation and conclusions are reasonable and logical

Application Process

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