Keystone Resort Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

Tumor Metabolism (B5)

Scientific Organizers: Lewis C. Cantley, Karen H. Vousden and Jeffrey A. Engelman


February 24—28, 2019

Keystone Resort, Keystone, Colorado, USA


Organized in collaboration with Cancer Research UK

Sponsored by Akebia Therapeutics and Cell Research


Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested.
BEWARE of booking lodging through companies unaffiliated with Keystone Symposia. Click here for more details.

Keystone Symposia is committed to maintaining a positive and respectful environment at its meetings. To this end, please review and comply with our policies.

DEADLINES:
*All deadlines end at 11:59 PM US Mountain Standard Time
Scholarship Deadline: Oct 23, 2018 [details]
Discounted Abstract Deadline: Oct 23, 2018 [details]
Abstract Deadline: Nov 27, 2018 [details]
Discounted Registration Deadline: Jan 8, 2019 [details]

If you have missed a deadline due to the US government shutdown, please contact our office.

Click here to view Cancellation Policy

Register Yourself Deadlines and Fees

Rates and Deadlines listed below are for the 2019-B5 "Tumor Metabolism" conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details
Before and On October 23, 2018 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details
After October 23, 2018 until January 13, 2019 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
Scholarship
More details
October 23, 2018 n/a
Discounted NON-STUDENT Registration
More details
Before and On January 8, 2019 845.00 USD
(includes 200.00 discount)
Regular NON-STUDENT Registration
More details
After January 8, 2019 1045.00 USD
Discounted STUDENT Registration
More details
Before and On January 8, 2019 620.00 USD
(includes 200.00 discount)
Regular STUDENT Registration
More details
After January 8, 2019 820.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will accept no liability for money loss through bank charges, transfers or currency fluctuations.




Discounted Abstract Deadline: October 23, 2018

*All deadlines end at 11:59 PM US Mountain Standard Time

Abstract Submission Fee: 100.00 USD*
Submission by this date receives 50.00 USD discount.
*50.00 USD will be applied to Registration Fee when you register

Abstract Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadlines. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract early allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • accept your abstract online
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
(The Abstract Deadline: is November 27, 2018)

Global Health Travel Award Deadline:

*All deadlines end at 11:59 PM US Mountain Standard Time


Global Health Travel Award Details: You MUST complete your Global Health Travel Award appplication by the Global Health Travel Award Deadline and complete the other required steps (verify your contact information and submit a recommendation letter) to be considered for a travel award.


Click here to learn more about Global Health Travel Awards.

Scholarship Deadline: October 23, 2018

*All deadlines end at 11:59 PM US Mountain Standard Time


Scholarship Details: You MUST submit your abstract by the Scholarship Deadline and complete the other required steps (submit a scholarship application and submit a mentor letter) to be considered for a scholarship.

Click here to learn more about Scholarships.

Abstract Deadline: November 27, 2018

*All deadlines end at 11:59 PM US Mountain Standard Time


Abstract Submission Fee: 100.00 USD*
*50.00 USD will be applied to Registration Fee when you register

Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadline. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract by the Abstract Deadline allows us to:

  • submit your abstract to organizers to be considered for a short talk
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
Abstracts submitted after the Abstract Deadline will NOT be considered for a short talk.

(Discounted Abstract Deadline: is October 23, 2018)

Discounted Registration Deadline: January 8, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time


Registration Fee: 845.00 USD* (includes 200.00 USD discount)
Student Registration Fee: 620.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

After the Discounted Registration Deadline:


Registration Fee: 1045.00 USD*
Student Registration Fee: 820.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

Registration spaces are limited and may fill prior to discounted registration deadline.

Please be advised that some meeting participants have received calls and emails from a number of different housing services, including "Exhibitors Housing Services," “Expo Housing Services,” "Global Housing," etc. THESE COMPANIES ARE NOT AFFILIATED WITH KEYSTONE SYMPOSIA and are not authorized by Keystone Symposia to contact you. These companies may tell you that the meeting is filling, without any actual knowledge to that effect, and pressure you into giving them your credit card number to make a lodging reservation with them.

We highly recommend that you not make a reservation with these companies or any other housing service! These companies' representations to participants have been misleading. Please report any calls or correspondence you might have received to Keystone Symposia and book only through lodging links in your Keystone Symposia account, an established travel agency or directly with the hotel(s) listed on our website.
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Sunday, February 24 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, February 28 with a closing plenary session from 17:00 to 19:15, followed by a social hour and entertainment. We recommend return travel on Friday, March 1 in order to fully experience the meeting.

SUNDAY, FEBRUARY 24

16:00—20:00
Arrival and Registration

Longs Peak Foyer
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Longs Peak Foyer

MONDAY, FEBRUARY 25

07:00—08:00
Breakfast

Longs/Quandary Peaks
08:00—09:00
Welcome and Keynote Address
Registered attendees can view abstracts starting on 01/24/2019

Grays Peak
* Lewis C. Cantley, Weill Cornell Medicine, USA

Matthew G. Vander Heiden, Massachusetts Institute of Technology, USA
Metabolic Requirements and Vulnerabilities of Cancer Cells

09:00—11:45
Cancer Cell Metabolism
Registered attendees can view abstracts starting on 01/24/2019

Grays Peak
* Dafna Bar-Sagi, New York University School of Medicine, USA

Joshua D. Rabinowitz, Princeton University, USA
Folate Metabolism in Cancer

Coffee Break

Christian Metallo, University of California, San Diego, USA
Coordinating Flux through Amino Acid and Lipid Metabolism in Cancer

Jeffrey A. Engelman, Novartis Institutes of BioMedical Research, USA
Talk Title to be Announced

Kevin Marks, Agios Pharmaceuticals, USA
Targeting Metabolic Vulnerabilities in Cancer

Gerta Hoxhaj, Harvard School of Public Health, USA
Short Talk: Acute Stimulation of NADP Synthesis Through Akt-Mediated Phosphorylation of NAD Kinase

Won Dong Lee, Technion - Israel Institute of Technology, Israel
Short Talk: SDH-Deficient Cells Increase Mitochondrial Reductive Flux through IDH2 Followed by a Reversal of CS Flux to Support Pyrimidine Biosynthesis

Shivani K. Thaker, University of California, Los Angeles, USA
Short Talk: Ketohexokinase is Important for Lung Tumor Growth

11:45—17:00
On Own for Lunch

11:45—13:00
Poster Setup

Longs/Quandary Peaks
13:00—22:00
Poster Viewing

Longs/Quandary Peaks
14:30—16:30
Workshop: Nutrient Transport and Dependencies

* Matthew G. Vander Heiden, Massachusetts Institute of Technology, USA

Ariel Bensimon, CeMM - Research Center for Molecular Medicine, Austria
Functional Integration of the Core Cancer Transportome

Kivanc Birsoy, Rockefeller University, USA
Nutrient Dependencies of Cancer Cells

Ayelet Erez, Weizmann Institute of Science, Israel
c-MYC Induces Arginine Metabolism to Promote Cancer Survival Under Glucose Starvation

Nora Kory, Whitehead Institute for Biomedical Research, USA
SFXN1 is A Mitochondrial Serine Transporter Required for One-Carbon Metabolism

Alexander Muir, Massachusetts Institute of Technology, USA
Absolute Quantification of Tumor Nutrients in Murine Models of Pancreatic and Lung Adenocarcinoma

Pankaj Kumar Singh, University of Nebraska Medical Center, USA
Metabolic Regulation of Therapy Outcome by Endoplasmic Reticulum Stress in Pancreatic Cancer

Ross Weber, Rockefeller University, USA
Loss of Mitochondrial Transporter SFXN1 Enables Cell Proliferation Under Limited Cysteine

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:15
Feeding the Cancer
Registered attendees can view abstracts starting on 01/24/2019

Grays Peak
* Karen H. Vousden, Crick Institute, UK

Eileen P. White, Rutgers University, USA
Autophagy Maintains Host and Tumor Metabolism and an Anti-Cancer Immune Response

Dafna Bar-Sagi, New York University School of Medicine, USA
Function and Regulation of Protein Scavenging in Mutant Ras Tumors

David M. Sabatini, Whitehead Institute for Biomedical Research, USA
Regulation of Growth by the mTOR Pathway

Sanjeethan C. Baksh, Rockefeller University, USA
Short Talk: Extracellular Serine Dependence Restricts Differentiation in Oncogenic Stem Cells

Jihye Yun†, Baylor College of Medicine, USA
Short Talk: High-Fructose Corn Syrup Enhances Intestinal Tumor Growth

Oliver Maddocks, University of Glasgow, UK
Short Talk: IDO1 Driven Tryptophan Utilisation Can Augment One-Carbon Metabolism in Pancreatic Cancer and Stromal Cells

19:15—20:15
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Longs/Quandary Peaks
19:30—22:00
Poster Session 1

Longs/Quandary Peaks

TUESDAY, FEBRUARY 26

07:00—08:00
Breakfast

Longs/Quandary Peaks
08:00—11:30
Metabolism, Microenvironment and Metastasis
Registered attendees can view abstracts starting on 01/24/2019

Grays Peak
* Elena Piskounova, Weill Cornell Medicine, USA

Martin O. Bergo, Karolinska Institutet, Sweden
Antioxidants and Metastasis

Richard White, Memorial Sloan Kettering Cancer Center, USA
A Role for Adipocytes in the Melanoma Microenvironment

Coffee Break

Aimee L. Edinger, University of California, Irvine, USA
Starving Cancer Cells to Death by Limiting Nutrient Access

Karen H. Vousden, Crick Institute, UK
Metabolic Control of ROS and Tumour Progression

Hamidullah Khan, University of Wisconsin Madison, USA
Short Talk: Metabolic Dynamics Modulate Cancer Progression Through mROS/HIF-1a Axis

Christopher J. Halbrook, University of Michigan, USA
Short Talk: Macrophage-Epithelial Metabolic Crosstalk Impairs Chemotherapy in Pancreatic Cancer

Xiaobo Li, H.Lee Moffitt Cancer Center, USA
Short Talk: TAp63 Regulated lncRNA and its Downstream Effector in Human Breast Cancer Cell Metabolism

11:30—17:00
On Own for Lunch

11:30—13:00
Poster Setup

Longs/Quandary Peaks
13:00—22:00
Poster Viewing

Longs/Quandary Peaks
16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:15
The Metabolism of ROS and Survival
Registered attendees can view abstracts starting on 01/24/2019

Grays Peak
* Gina DeNicola, Moffitt Cancer Center, USA

Navdeep S. Chandel, Northwestern University, USA
Mitochondrial Metabolism and Cancer

Thales Papagiannakopoulos, New York University School of Medicine, USA
Uncovering Metabolic Bottlenecks in KRAS-Driven Lung Cancer

David A. Tuveson, Cold Spring Harbor Laboratory, USA
ROS and Mitophagy Dependencies in Pancreatic Cancer

Veerle Daniels, Dana-Farber Cancer Institute, USA
Short Talk: Metabolic Perturbation Sensitizes Triple-Negative Breast Cancer Cells to BH3 Mimetics

Kenneth Olive, Columbia University, USA
Short Talk: Modulation of Cystine Import Induces Pancreatic Cancer-Selective Ferroptosis

George Poulogiannis, Institute of Cancer Research, London, UK
Short Talk: iKnife Couples Oncogenic PIK3CA with an Arachidonic Acid-Mediated Eicosanoid Storm

19:15—20:15
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Longs/Quandary Peaks
19:30—22:00
Poster Session 2

Longs/Quandary Peaks

WEDNESDAY, FEBRUARY 27

07:00—08:00
Breakfast

Longs/Quandary Peaks
08:00—11:30
Metabolism Outside the Tumor
Registered attendees can view abstracts starting on 01/24/2019

Grays Peak
* Kathryn E. Wellen, University of Pennsylvania, USA

Ralph J. DeBerardinis, University of Texas Southwestern Medical Center, USA
Metabolic Perturbations and Human Disease

Katja A. Lamia, The Scripps Research Institute, USA
Connecting Circadian Clocks and Cancer

Coffee Break

Vuk Stambolic, Ontario Cancer Institute/University Health Network, Canada
Obesity And Cancer

Tak W. Mak, Campbell Family Institute for Breast Cancer, Canada
Metabolic Adaptation in Hemopoietic Malignancies

Julian J. Lum, BC Cancer, Canada
Short Talk: Autophagy Suppresses CD8+ T Cell Antitumour Responses Through Glucose-Dependent Changes in Transcription

Steven Zhao, University of Pennsylvania, USA
Short Talk: Dietary Fructose Promotes de novo Lipogenesis from Microbiome-Derived Acetate

11:30—17:00
On Own for Lunch

11:30—13:00
Poster Setup

Longs/Quandary Peaks
13:00—22:00
Poster Viewing

Longs/Quandary Peaks
16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:15
Metabolic Adaptation and the Response to Therapy
Registered attendees can view abstracts starting on 01/24/2019

Grays Peak
* Jeffrey A. Engelman, Novartis Institutes of BioMedical Research, USA

Alec Kimmelman, New York University Langone Medical Center, USA
Identifying Metabolic Dependencies in Pancreatic Cancer

Lewis C. Cantley, Weill Cornell Medicine, USA
PI 3-Kinase and Cancer Metabolism

Kathryn E. Wellen, University of Pennsylvania, USA
Acetyl-CoA metabolism in chromatin regulation and tumorigenesis

Lei Shi, Massachusetts General Hospital, USA
Short Talk: Leveraging Reprogrammed Metabolism to Define Selective Vulnerabilities of IDH1 Mutated Cholangiocarcinoma Cells

Carmen Sivakumaren, Harvard University, USA
Short Talk: Targeting the PI5P4K Lipid Kinase Family in Cancer using Novel Covalent Inhibitors

Liang Zhao, Johns Hopkins University School of Medicine, USA
Short Talk: Inhibition Proximal Glycolysis and Disruption of Krebs Cycle by Broad Targeting Glutamine Metabolism for Cancer Therapy

19:15—20:15
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Longs/Quandary Peaks
19:30—22:00
Poster Session 3

Longs/Quandary Peaks

THURSDAY, FEBRUARY 28

07:00—08:00
Breakfast

Longs/Quandary Peaks
08:00—11:30
Modelling Cancer Metabolism
Registered attendees can view abstracts starting on 01/24/2019

Grays Peak
* Joshua D. Rabinowitz, Princeton University, USA

Sarah-Maria Fendt, VIB Leuven, Belgium
Nutrient Metabolism in Cancer Cells

Costas A. Lyssiotis, University of Michigan, USA
Metabolic Networks in the Tumor Microenvironment

Coffee Break

Saverio Tardito, Beatson Institute for Cancer Research, Scotland
Reformulating Cell Culture Medium to Improve the Metabolic Fidelity of in vitro Models of Cancer

Jason R. Cantor, Morgridge Institute for Research; UW-Madison, USA
Short Talk: Use of Physiologic Media to Explore Genetic Dependencies in Cancer

Henry Däbritz, CRUK Beatson Institute, UK
Short Talk: Oncogenic Hras and Loss of Succinate Dehydrogenase B Synergise to Drive Kidney Neoplasia in a Genetically Engineered Mouse Model

Ashley Solmonson, University of Texas Southwestern Medical Center, USA
Short Talk: Inborn Errors of Metabolism: Evaluating Critical Metabolic Regulators of Mammalian Development

11:30—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:00
Imaging Cancer Metabolism In Vitro and In Vivo
Registered attendees can view abstracts starting on 01/24/2019

Grays Peak
Kevin M. Brindle, University of Cambridge, UK
Imaging Tumor Metabolism with Hyperpolarized 13C-Labelled Metabolites – From Mouse to Man

Josephine Bunch, University of Birmingham, UK
Imaging Tumor Metabolism by Multi-Scale Mass Spectrometry Imaging

Vsevolod V. Belousov, Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry RAS, Russia
Imaging and Manipulating Redox in Cells

19:00—19:15
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 01/24/2019

Grays Peak
19:15—20:15
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Longs/Quandary Peaks
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Longs/Quandary Peaks

FRIDAY, MARCH 1

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Akebia Therapeutics Organized in collaboration with Cancer Research UK
Cell Research
 

We gratefully acknowledge additional support from these exhibitors at this conference:

Don Whitley Scientific Limited HypOxygen
Please stop by to meet these exhibitors during the conference.


We gratefully acknowledge additional support for this conference from:

Cayman Chemical Company eLife

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Novartis Institutes for BioMedical Research


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676