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This meeting took place in 2012



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Cancer and Metabolism (Q3)


Organizer(s) Reuben J. Shaw and David M. Sabatini
February 12—17, 2012
Fairmont Banff Springs • Banff, Alberta Canada
Abstract Deadline: Oct 13, 2011
Late Abstract Deadline: Nov 14, 2011
Scholarship Deadline: Oct 13, 2011
Early Registration Deadline: Dec 12, 2011

Sponsored by Astellas Pharma Inc., Celgene Corporation, Pfizer Inc. and Takeda Pharmaceutical Company Limited


Summary of Meeting:
Although altered glucose metabolism was first noted as a characteristic of tumor cells by Otto Warburg in the 1920s, the molecular underpinning for this observation did not begin to be appreciated fully until the past decade. This area has exploded over the last five years with the identification of extensive interactions of genuine tumor suppressor genes and oncogenes with metabolic control. The increased biosynthetic needs of tumor cells demand a reprogramming of cellular metabolism, which also creates increased energy demands and makes tumor cells more vulnerable to interventions targeting their metabolism. The goal of the Keystone Symposia meeting on Cancer and Metabolism is to bring together leaders in the fields of cancer and metabolic control with those studying the signaling pathways linking and governing each. The latest discoveries will be discussed as well as how this knowledge can be exploited to design future cancer therapeutics. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on Advances in Hypoxic Signaling: From Bench to Bedside, which will share a keynote address and a plenary session with this meeting.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SUNDAY, FEBRUARY 12

15:00—19:30
Registration

Van Horne Foyer
18:15—19:15
Refreshments

Van Horne Foyer
19:15—21:30
Welcome and Keynote Session (Joint)
Meeting has ended...abstracts no longer viewable online.

Van Horne A-B
* Volker H. Haase, Vanderbilt University, USA

Peter J. Ratcliffe, University of Oxford, UK
Regulation of Hypoxic Signaling: Past and Future

* Reuben J. Shaw, The Salk Institute for Biological Studies, USA

Craig B. Thompson, Memorial Sloan Kettering Cancer Center, USA
Metabolism and Cancer Are Intertwined


MONDAY, FEBRUARY 13

07:00—08:00
Breakfast

Mezzanine 2
08:00—11:15
Oncogene Control of Metabolism
Meeting has ended...abstracts no longer viewable online.

Van Horne A-B
* David M. Sabatini, Whitehead Institute for Biomedical Research, USA

Lewis C. Cantley, Weill Cornell Medicine, USA
PI3K and Mitogenic Signals Control Metabolism

Michael Pollak, Jewish General Hospital, Canada
Actions of Insulin and myc on Cancer Metabolism are Influenced by Metformin

Eileen P. White, Rutgers University, USA
Role of Autophagy and Metabolic Control in Tumorigenesis

Almut Schulze, University of Würzburg/Theodor-Boveri Institute, Germany
EMBO Young Investigator Lecture: Regulation of Lipogenesis by the Akt/mTORC1 Pathway and Its Role in Cell Growth and Cancer

E. Alejandro Sweet-Cordero, Stanford University, USA
Short Talk: Oncogenic Kras Inhibits Mitochondrial Metabolism by Regulating the Pyruvate Dehydrogenase Complex under Conditions of Nutrient Stress

Taru Muranen, Harvard Medical School, USA
Short Talk: Inhibition of PI3K/mTOR Leads to Adaptive Resistance in Matrix-Attached Cancer Cells

08:00—11:15
Transcriptional and Non-Transcriptional Regulation of Hypoxia Responses
Meeting has ended...abstracts no longer viewable online.

Van Horne C
* Agnes Görlach, German Heart Center Munich, TU Munich, Germany

Johanna Myllyharju, University of Oulu, Finland
Enzymatic Responses to Hypoxia

Murray L. Whitelaw, Adelaide University, Australia
Signaling through bHLH/PAS Domain Proteins

Peter F. Carmeliet, University of Leuven, VIB, Belgium
Endothelial Metabolism: A Target in Angiogenesis?

Peppi Koivunen, University of Oulu, Finland
Short Talk: Transformation by the R Enantiomer of 2-Hydroxyglutarate Linked to EglN Activation

Roland H. Wenger, University of Zürich, Switzerland
Oxygen-Responsive Transcriptional Networks

Florian Riess, German Heart Center Munich, Germany
Short Talk: HIF-3alpha Inhibits HIF-2 in Vascular Endothelial Cells by Dimerization with ARNT

09:20—09:40
Coffee Break

Van Horne Foyer
11:15—13:00
Poster Setup

Mezzanine 2
11:15
On Own for Lunch and Recreation

13:00—22:00
Poster Viewing

Mezzanine 2
14:30—16:30
Workshop: Health Disparities (Joint). Supported by Novartis Institutes for BioMedical Research

Van Horne A-B
* Timothy R. Rebbeck, University of Pennsylvania School of Medicine, USA
Introduction and Overview

Josef Prchal, University of Utah, USA
Congenital Disorders of Hypoxic Sensing and Tibetan Hypoxic Adaptation

Suzanne D. Conzen, University of Chicago, USA
Effects of Social Stressors on Cancer Progression: Potential Metabolic Mechanisms

16:30—17:00
Coffee Available

Van Horne Foyer
17:00—19:00
HIF Signaling in Cancer (Joint)
Meeting has ended...abstracts no longer viewable online.

Van Horne A-B
* Eyal Gottlieb, Technion - Israel Institute of Technology, Israel

William G. Kaelin, Jr., Dana-Farber Cancer Institute, USA
Cancer Metabolism and 2-Oxoglutarate-dependent Dioxygenases

M. Celeste Simon, University of Pennsylvania, USA
Genetic Dissection of HIF Function in Cancer and Stem Cells

Gregg L. Semenza, Johns Hopkins University School of Medicine, USA
Multiple Roles of Hypoxia-Inducible Factors in Breast Cancer Metastasis

Till Acker, University of Giessen, Germany
Short Talk: Control of Tumor Growth by Prolyl-Hydroxylases

19:00—20:00
Social Hour with Lite Bites

Mezzanine 2
19:30—22:00
Poster Session 1

Mezzanine 2

TUESDAY, FEBRUARY 14

07:00—08:00
Breakfast

Mezzanine 2
08:00—11:15
mTOR Signaling in Growth and Metabolic Control
Meeting has ended...abstracts no longer viewable online.

Van Horne A-B
* Reuben J. Shaw, The Salk Institute for Biological Studies, USA

David M. Sabatini, Whitehead Institute for Biomedical Research, USA
Regulation of Growth by the mTOR Pathway

John Blenis, Weill Cornell Medical College, USA
mTOR Complex 1, Metabolism and Cell Growth Control

Brendan D. Manning, Harvard School of Public Health, USA
mTOR Links Oncogenic Signaling to Tumor Cell Metabolism

Kun-Liang Guan, University of California, San Diego, USA
Nutrient and mTOR Signals

Camilla Norrmén, ETH Zurich, Switzerland
Short Talk: mTOR Signaling in Myelination of Peripheral Nerves

David A. Guertin, University of Massachusetts Medical School, USA
Short Talk: Tissue Growth Control by PI3K-mTOR Signaling

08:00—11:15
Metabolic Adaptation to Hypoxia
Meeting has ended...abstracts no longer viewable online.

Van Horne C
* Dörthe M. Katschinski, Georg August University, Germany

Randall S. Johnson, University of Cambridge, UK
Hypoxia and Metabolism

Lorenz Poellinger, Karolinska Institutet, Sweden
Epigenetic Control of Hypoxia Gene Expression and Metabolic Stress

Jenny E. Gunton, University of Sydney, Australia
HIF-1alpha in the Development of Type 2 Diabetes and Metabolic Syndrome

Calvin Kuo, Stanford University, USA
Short Talk: Hypoxic Regulation of Hepatic Glucose Metabolism

Martina U. Muckenthaler, Children's Hospital, University of Heidelberg, Germany
Oxygen-Dependent Regulation of Iron Metabolism

Julián Aragonés Lopez, Research Institute Princesa, Spain
Short Talk: Essential Role of the HIF1alpha Osygen-Sensing Pathway in Controlling Body Weight

09:20—09:40
Coffee Break

Van Horne Foyer
11:15—13:00
Poster Setup

Mezzanine 2
11:15
On Own for Lunch and Recreation

13:00—22:00
Poster Viewing

Mezzanine 2
14:30—16:30
Workshop 1: Hot Topics in Cancer Metabolism I

Van Horne A-B
* Lewis C. Cantley, Weill Cornell Medicine, USA

Jessica J. Howell, Harvard School of Public Health, USA
Mechanisms and Consequences of mTORC1 Inhibition by Pharmacological Doses of Metformin

Alfredo Csibi, Harvard Medical School, USA
The mTORC1 Pathway Regulates Glutamine Metabolism

Peter Rahl, Massachusetts Institute of Technology, USA
c-Myc Overexpression Drives Binding to Distinct Enhancers in Different Cancers

Kevin J. Williams, University of California, Los Angeles, USA
A Critical Role for SREBP1 in the Warburg Effect and Tumor Growth

Kivanc Birsoy, Rockefeller University, USA
Use of Functional Genomic Screens and Nutrostats to Identify Metabolic Liabilities of Cancer Cells under Limiting Glucose and Oxygen Conditions

Katharine V. Brown, University of California, Berkeley, USA
SIRT3 Regulates Hematopoeitic Stem Cell Aging

Lluis Fajas, Université de Lausanne, Switzerland
Cdk4-E2F1 Mediate a Metabolic Switch in Normal and in Cancer Cells and Facilitate Whole Body Metabolic Adaptation to Cancer

Shi Chi Leow, ASTAR Singapore Institute for Clinical Sciences, Singapore
NF-kappaB Controls Energy Homeostasis and Metabolic Adaptation by Upregulating Mitochondrial Respiration

14:30—16:30
Workshop 1: Student/Postdoc Workshop

Van Horne C
* Pablo Wappner, Fundacion Instituto Leloir, Argentina

Brooke M. Emerling, Sanford Burnham Prebys Medical Discovery Institute, USA
Identification of CDCP1 as a HIF-2alpha Target Gene Involved in the Regulation of Cancer Cell Migration and Metastasis

Sofie Deschoemaeker, University of Leuven, Belgium
Gene-Targeting of PHD2 Oxygen Sensor Improved Tumor Response to Chemotherapy and Prevents Side-Toxicity in Mice

Jung-whan Kim, University of Texas, USA
Deletion of Hypoxia Inducible Factor-1alpha (HIF-1alpha) In Stromal Fibroblasts Accelerates Mammary Tumor Progression through Vascular Normalization

Muriel R. Kaufmann, University of Zürich, Switzerland
Presenilin Membrane Proteases as Novel Regulators of HIF via the APP/AICD Cleavage Cascade

Pardeep Heir, University of Toronto, Canada
HIFalpha Binding to VHL Cues DCNL1 Recruitment to Trigger CUL2 Neddylation

Kirsten Schneider, University Clinic Essen, Germany
Factor Inhibiting HIF-1 Modulates Protein Interactions of ASPP2

Yukimi Sakoda, Yamaguchi University, Japan
Regulation of HIF-1alpha Erythropoiesis by HVEM

Johannes Schödel, Universitätsklinikum Erlangen, Germany
Common Genetic Variants at the 11q13.3 Renal Cancer Susceptibility Locus Influence Binding of HIF to an Enhancer of Cyclin D1 Expression

16:30—17:00
Coffee Available

Van Horne Foyer
17:00—19:00
Metabolic Stress Control
Meeting has ended...abstracts no longer viewable online.

Van Horne A-B
* Jared Rutter, University of Utah, USA

D. Grahame Hardie, University of Dundee, UK
AMPK – A Metabolic Master Switch Activated by Many Anti-Cancer Drugs

Reuben J. Shaw, The Salk Institute for Biological Studies, USA
LKB1 and AMPK Signaling in Cancer and Metabolism

Kevin Struhl, Harvard Medical School, USA
Anti-Cancer Effects of Metformin

Linda Z. Penn, Princess Margaret Cancer Centre, Canada
Short Talk: Targeting the Mevalonate Pathway in Cancer

17:00—19:00
Systemic Responses to Hypoxia and High Altitude
Meeting has ended...abstracts no longer viewable online.

Van Horne C
* Josef Prchal, University of Utah, USA

Max Gassmann, University of Zürich, Switzerland
Erythropoietin and Exercise Performance

José López-Barneo, Hospital Universitario Virgen del Rocío, Spain
Contrasting Effects of Chronic Hypoxia on Central and Peripheral Neurogenic Centers

Cynthia M. Beall, Case Western Reserve University, USA
Human Genetic Adaptation to High Altitude

Donald A. McClain, University of Utah School of Medicine, USA
Short Talk: Metabolic Consequences of Genetic Adaptation to High Altitude in Tibetans

19:00—20:00
Social Hour with Lite Bites

Mezzanine 2
19:30—22:00
Poster Session 2

Mezzanine 2

WEDNESDAY, FEBRUARY 15

07:00—08:00
Breakfast

Mezzanine 2
08:00—11:15
Connecting Metabolic Pathways to Growth Control
Meeting has ended...abstracts no longer viewable online.

Van Horne A-B
* Jeffrey C. Rathmell, Vanderbilt University, USA

Jared Rutter, University of Utah, USA
Good and Bad Growth: The Virtues and Vices of Mitochondria and Metabolism

Matthew G. Vander Heiden, Massachusetts Institute of Technology, USA
Regulation of Metabolic Pathways to Support Anabolic Metabolism

Richard L. Possemato, New York University School of Medicine, USA
Short Talk: Identification of Metabolic Liabilities in Breast Cancer

Heather Christofk, University of California, Los Angeles, USA
Short Talk: Role of MCT1 in Cancer Metabolism

Andrew Mullen, University of Texas Southwestern Medical Center, USA
Short Talk: A Novel Pathway of Glutamine Metabolism Fuels Growth in Cancer Cells with Defective Mitochondria

Christian Metallo, University of California, San Diego, USA
Short Talk: Reductive Tricarboxylic Acid Metabolism of Glutamine Mediates Lipogenesis under Hypoxia

08:00—11:15
Oxygen Signaling in Tissue Injury, Repair and Inflammation
Meeting has ended...abstracts no longer viewable online.

Van Horne C
* Larrisa A. Shimoda, Johns Hopkins School of Medicine, USA

Bernhard Brüne, Goethe University Frankfurt, Germany
Oxygen-Dependent Regulation of Macrophage Function

Cormac Taylor, University College Dublin, Ireland
Hypoxia and Inflammation

Benoit Sebastien Marteyn, Institut Pasteur, France
Short Talk: Hypoxic Response during Pathogenic Enterobacterium Shigella Infection

Eric L. Campbell, , UK
Short Talk: Transmigrating Neutrophils Induce “Transcriptional Imprinting” within the Epithelium and Reveals a Fundamental Role for Hypoxic Signaling Attributable to Localized Oxygen Depletion

Holger K. Eltzschig, University of Colorado Denver, USA
Hypoxia Responses in Acute Ischemia-Reperfusion Injury

Volker H. Haase, Vanderbilt University, USA
Tissue Responses to Chronic Hypoxia

09:20—09:40
Coffee Break

Van Horne Foyer
11:15—13:00
Poster Setup

Mezzanine 2
11:15
On Own for Lunch and Recreation

13:00—22:00
Poster Viewing

Mezzanine 2
14:30—16:30
Workshop 2: Technological Advances in Hypoxia Research

Van Horne C
* Frank S. Lee, University of Pennsylvania School of Medicine, USA

David T. Eddington, University of Illinois, Chicago, USA
Microfluidic Oxygenated Substrates for Studying Ischemia Reperfusion and Intermittent Hypoxia

Patrick R. Arsenault, University of Pennsylvania, USA
Effects of Mutations in Mouse Phd2 on Hematological and Physiological Phenotypes

Analía Nuñez O´Mara, Center for Cooperative Research in Biosciences, Spain
The Role of SUMOylation in the Cellular Response to Hypoxia

Violaine Sée, University of Liverpool, UK
Single Cell Imaging and Mathematical Modeling to Depict the Role of the Prolyl Hydroxylase-Negative Feedback Loop on HIF-1alpha Dynamics

Othon Iliopoulos, Massachusetts General Hospital Cancer Center, USA
Regulation of Reductive TCA Cycle Metabolism by Hypoxia-HIF-VHL Signaling: New Opportunities for Therapy of Renal Cell Carcinoma

Antonio Martinez-Ruiz, Hospital Santa Cristina, IIS Princesa, Spain
Differential Redox Proteomics Identify Proteins Reversibly Oxidized in Cysteines in Endothelial Cells in Response to Acute Hypoxia

Ali Tavassoli, University of Southampton, UK
Inhibition of Hypoxia Signalling with Cyclic Peptide Inhibitors of HIF Heterodimerization

16:30—17:00
Coffee Available

Van Horne Foyer
17:00—19:00
Lessons from Mouse Models
Meeting has ended...abstracts no longer viewable online.

Van Horne A-B
* Kay F. Macleod, University of Chicago, USA

John L. Cleveland, The Scripps Research Institute, USA
Blocking Lactate Export by Inhibiting the Myc target Mct1 Disables Cancer Cell Metabolism and Impairs Tumorigenesis

Ana Maria Cuervo, Albert Einstein College of Medicine, USA
Selective Autophagy and Oncogenesis

Karen H. Vousden, Francis Crick Institute, UK
Control of Metabolism by the p53 Pathway

Nada Y. Kalaany, Boston Children's Hospital at Harvard Medical School, USA
Short Talk: Adjacent Tumors Cohabiting the Same Tissue Respond Differentially to Dietary Restriction

17:00—19:00
Cellular Stress Responses to Hypoxia
Meeting has ended...abstracts no longer viewable online.

Van Horne C
* Joachim Fandrey, University Duisburg-Essen, Germany

Paul T. Schumacker, Northwestern University, USA
Mitochondrial ROS Signaling under Hypoxic Stress

Ezra Burstein, University of Texas Southwestern Medical Center, USA
COMMD Proteins and Hypoxic Stress

Masayuki Yamamoto, Tohoku University Graduate School of Medicine, Japan
Hypoxia-Inducible and Tissue-Specific Erythropoietin Gene Regulation

Ho Jeong Kwon, Yonsei University, South Korea
Short Talk: Terpestacin and UQCRB, a New Small Molecule and its Target Protein in Hypoxia Signaling

19:00—20:00
Social Hour with Lite Bites

Mezzanine 2
19:30—22:00
Poster Session 3

Mezzanine 2

THURSDAY, FEBRUARY 16

07:00—08:00
Breakfast

Mezzanine 2
08:00—11:15
Novel Mechanisms in Metabolic Control
Meeting has ended...abstracts no longer viewable online.

Van Horne A-B
* Matthew G. Vander Heiden, Massachusetts Institute of Technology, USA

Eyal Gottlieb, Technion - Israel Institute of Technology, Israel
The use of Metabolomics to Discover Novel Metabolic Networks and New Targets for Cancer Treatment

Jeffrey C. Rathmell, Vanderbilt University, USA
Glucose Uptake and Metabolic Links to Cell Death

Joan S. Brugge, Harvard Medical School, USA
Extracellular Matrix, Growth Factor and Oncogene Control of Cellular Survival and Metabolism

Richard A. Cerione, Cornell University, USA
A New Way to Look at Cancer Signaling and Intervention

Kay F. Macleod, University of Chicago, USA
Short Talk: BNip3 Limits HIF-1alpha Stabilization and Metastasis in a Mouse Model of Breast Cancer through Effects on Mitochondrial Integrity and ROS Generation

Gerald Hoefler, Medical University of Graz, Austria
Short Talk: Ablation of Triglyceride Lipases Protects from Cancer Associated Cachexia

08:00—11:15
Therapeutic Targeting of Hypoxia Response Pathways
Meeting has ended...abstracts no longer viewable online.

Van Horne C
* Roland H. Wenger, University of Zürich, Switzerland

Michael H. Rabinowitz, Akebia Therapeutics, Inc., USA
Drug Development: Targeting Prolyl Hydroxylases

Kai-Uwe Eckardt, University Clinic Erlangen, Germany
Clinical Application of Prolyl-Hydroxylase Inhibition

Karen A. Vincent, Genzyme Corporation, USA
Cardiovascular Gene Therapy: Targeting Hypoxia

Christian Stockmann, PARCC – Paris Cardiovascular Research Center, France
Short Talk: Tuning Tumor Oxygenation and Reshaping the Tumor Microenvironment by Compartmentalized VEGF Expression - Impact on Tumor Relapse

Mark W. Dewhirst, Duke University Medical Center, USA
Aerobic Exercise Training Decreases Tumor Growth Rates in Murine Models of Breast Cancer

Alessio Ciulli, University of Dundee, College of Life Sciences, UK
Short Talk: Targeting the von Hippel-Lindau (pVHL) E3 Ubiquitin Ligase Multisubunit Protein Complex using Small Molecules to Disrupt its Interaction with Hypoxia Inducible Factor 1 alpha (Hif-1a)

09:00—09:20
Coffee Break

Van Horne Foyer
11:15
On Own for Lunch and Recreation

14:30—16:30
Workshop 2: Hot Topics in Cancer Metabolism II

Van Horne A-B
* Brendan D. Manning, Harvard School of Public Health, USA

Cristina Muñoz-Pinedo, Institut d'Investigacio Biomedica de Bellvitge, Spain
Mechanisms of Tumor Cell Death Induced by Inhibition of Glucose Metabolism

Patrick J. Pollard, University of Edinburgh, UK
Candidate Roles for Protein Succination in Altered Cellular Metabolism and Oncogenesis

Charles Kung, Agios Pharmaceuticals Inc., USA
Induced Dependency on Amino Acid Metabolism in Proliferating Cancer Cells Upon PKM2 Activation

William J. Israelsen, Massachusetts Institute of Technology, USA
Role of PKM2 in Tumor Development

Patrick S. Ward, Massachusetts General Hospital, USA
Hypoxia Promotes IDH2-Dependent Carboxylation of alpha-Ketoglutarate to Citrate to Support Cell Growth and Viability

David B. Shackelford, University of California, Los Angeles, USA
LKB1/STK11 Deficiency Sensitizes Genetically Engineered Mouse Models of Non Small Cell Lung Cancer to Phenformin Therapy

Brandon Faubert, University of Texas Southwestern Medical Center, USA
The Energy Sensor AMP-activated Protein Kinase (AMPK) Mediates a Metabolic Switch to Warburg Metabolism in Cancer

Robert E. Lewis, University of Nebraska Medical Center, USA
Coordinate Detection of New Targets and Small Molecules in Cancer Therapy

16:30—17:00
Coffee Available

Van Horne Foyer
17:00—19:00
Metabolic Drugs as Cancer Therapeutics
Meeting has ended...abstracts no longer viewable online.

Van Horne A-B
* David M. Sabatini, Whitehead Institute for Biomedical Research, USA

Paul S. Mischel, University of California, San Diego, USA
Targeting Metabolic Pathways in EGFR-Activated Glioblastoma

Kevin Marks, Agios Pharmaceuticals, USA
Targeting Metabolic Rewiring in Cancer

Beat Nyfeler, Novartis Institutes for BioMedical Research, Switzerland
Targeting mTOR in Cancer

Jonathan Mandelbaum, Accelerator Life Science Partners, USA
Short Talk: Generation of Chemical and Genetic Tools for Inhibiting ATG7 Function

17:00—19:00
Hypoxic Signaling in Tumor Development and Progression
Meeting has ended...abstracts no longer viewable online.

Van Horne C
* Thomas Kietzmann, University of Oulu, Finland

Amato J. Giaccia, Stanford University, USA
Hypoxia and Metastasis

Elizabeth Koch, Princess Margaret Hospital/Ontario Cancer Institute, Canada
Short Talk: Hypoxic Regulation of DICER1, microRNA, and their Influence on the Cancer Phenotype

Margaret Ashcroft, University of Cambridge, UK
Mitochondrial Protein Regulators of Hypoxia Signaling and Tumour Progression

Michael Ohh, University of Toronto, Canada
Non-Canonical Regulation of Gene Expression via HIF

19:00—20:00
Social Hour with Lite Bites

Mezzanine 2
20:00—23:00
Entertainment

Mezzanine 2

FRIDAY, FEBRUARY 17

 
Departure


*Session Chair †Invited, not yet responded.


We gratefully acknowledge support for this conference from:


Directors' Fund

These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.

Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Astellas Pharma Inc. Celgene Corporation
Pfizer Inc. Takeda Pharmaceutical Company Limited

We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13CA162886-01

The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

We gratefully acknowledge additional support for this conference from:

Cell Signaling Technology, Inc. Coy Laboratory Products Inc.
Educational grant from Millennium Pharmaceuticals, Inc., The Takeda Oncology Company Myriad-RBM
Novartis Institutes for BioMedical Research Novus Biologicals, Inc.
Seahorse Bioscience, Inc. Zymo Research Corporation

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



EMBO Young Investigator Programme

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

EMBO (European Molecular Biology Organization)

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations

If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Nick Dua, Senior Director, Communications, Email: nickd@keystonesymposia.org,
Phone:+1 970-262-1179