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Clarion Hotel Sign Floorplan

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This meeting took place in 2013



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Human Genomics and Personalized Medicine (E3)


Organizer(s) Kelly A. Frazer and Geoffrey S. Ginsburg
June 17—21, 2013
Clarion Hotel Sign • Stockholm, Sweden Sweden
Abstract Deadline: Feb 20, 2013
Late Abstract Deadline: Mar 19, 2013
Scholarship Deadline: Feb 20, 2013
Early Registration Deadline: Apr 16, 2013

Organized in collaboration with Knut and Alice Wallenberg Foundation and Science for Life Laboratory - Stockholm. Sponsored by AstraZeneca, Boehringer Ingelheim Pharmaceuticals, Inc., H3 Biomedicine Inc., Nestlé Institute of Health Sciences and Onyx Pharmaceuticals, Inc.

Summary of Meeting:
The last decade has seen considerable progress in our understanding of genomics and the era of personalized medicine is just around the corner. Importantly, emerging data on the structure and function of the human genome are providing insights into the molecular basis of inherited disease and providing opportunities to improve human health through new approaches to diagnostics and therapy. These advances will impact all aspects of human health, ranging from cancer to other chronic diseases. Making genomic medicine a reality requires novel collaborations between basic scientists, translational scientist, regulatory bodies and health insurance bodies. Therefore, the Keystone Symposia meeting on Human Genomics and Personalized Medicine is a timely opportunity to bring leading researchers together to discuss the critical issues facing this emerging field. The meeting will focus on various aspects of the field, including genomics and the transition to genomic medicine (clinical care based on genomic information), the analysis of complex data sets, the development of robust bio-repositories, public access to large data sets being generated from funds from NIH and other agencies, and key regulatory issues and public policy. Importantly, the meeting will help establish communication and interactions enabling a faster implementation of genomic medicine and will also benefit from its international participation by highlighting areas of research that are of global concern.

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Conference Program    Print  |   View meeting in 12 hr (am/pm) time


MONDAY, JUNE 17

12:00—20:00
Arrival and Registration

Foyer
15:30—16:00
Coffee & Snacks Available

Foyer
16:00—17:00
Welcome and Keynote Address
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

B 1-2
* Geoffrey S. Ginsburg, Duke University, USA
Welcome Remarks

John Bell, University of Oxford, UK
Bringing Genomics to the Bedside

17:00—19:00
Breakthroughs in Genomic and Personalized Medicine
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

B 1-2
* Kelly A. Frazer, University of California, San Diego, USA

Peter Mueller, Vertex Pharmaceuticals Incorporated, USA
Kalydeco: Targeting the G551D Mutation in CF

Geoffrey S. Ginsburg, Duke University, USA
Novel Host-Based Approaches to the Diagnosis of Infectious Disease

Stephen F. Kingsmore, Children’s Mercy Hospital, USA
Pediatric Genomic Medicine


TUESDAY, JUNE 18

07:30—08:30
Breakfast

Individual Hotel
07:30—08:00
Poster Setup

B3
08:00—15:30
Poster Viewing

B3
08:30—11:30
Genomes and Biology
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

B 1-2
* Thomas J. Hudson, Ontario Institute for Cancer Research, Canada

Mathias Uhlén, Royal Institute of Technology, Sweden
Defining the Human Tissue-Specific Proteome based on Transcriptomics and Antibody-Based Protein Profiling

Kelly A. Frazer, University of California, San Diego, USA
Genomic Approaches to Understanding Cancer Progression

Martin J. Blaser, New York University School of Medicine, USA
Perturbing the Early Life Microbiome and its Consequences

Andrew P. Feinberg, Johns Hopkins University School of Medicine, USA
The Epigenetic Basis of Common Human Disease

Lili Milani, University of Tartu, Estonia
Short Talk: Genome-Wide DNA Methylation and Gene Expression Changes in Whole Blood, CD4+ and CD8+ T-Cells during Healthy Aging

09:50—10:10
Coffee Break

Foyer/Hyllan
11:30—12:30
Lunch

Atrium/Foyer
12:30—15:00
Poster Session 1

B3
15:00—15:30
Coffee Available

Foyer/Hyllan
15:30—18:30
Cancer Genomics and Applications
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

B 1-2
* Andrew P. Feinberg, Johns Hopkins University School of Medicine, USA

Paul S. Mischel, University of California, San Diego, USA
The Cancer Genome Atlas and the Future of Cancer Diagnosis and Treatment

Thomas J. Hudson, Ontario Institute for Cancer Research, Canada
Linking Cancer Treatment Decisions with Large-Scale Mutation Surveys

Jessica Nordlund, Uppsala University, Sweden
Short Talk: The DNA Methylation Landscape of Pediatric Acute Lymphoblastic Leukemia

Steven Shak, Genomic Health Inc., USA
Translating Genomics into Clinical Practice: Lessons from Oncotype DX

Hiroyuki Mano, University of Tokyo, Japan
Targeting Essential Growth Drivers in Human Cancer

18:30—00:00
On Own for Dinner


WEDNESDAY, JUNE 19

07:30—08:30
Breakfast

Individual Hotel
08:30—11:30
Advances and Challenges in the Field
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

B 1-2
* Kelly A. Frazer, University of California, San Diego, USA

Janet Woodcock, US Food and Drug Administration, USA
A Regulatory Pathway to Personalized Medicine

Dan M. Roden, Vanderbilt University School of Medicine, USA
Integration and Implementation of Genetic Information into Health Systems

Jill P. Mesirov, Broad Institute, USA
Computational Approaches for Genomic Medicine

Howard J. Jacob, Medical College of Wisconsin, USA
Advances in Clinical Sequencing

X. Sunney Xie, Harvard University, USA
Short Talk: Single-Cell Genomics: Life at the Single Molecule Level

09:50—10:10
Coffee Break

Foyer/Hyllan
11:30—13:00
Poster Setup

B3
11:30—12:30
Lunch

Atrium/Foyer
12:30—22:00
Poster Viewing

B3
12:30—15:00
Pharmacogenomics
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

B 1-2
* Dan M. Roden, Vanderbilt University School of Medicine, USA

Alan R. Shuldiner, University of Maryland School of Medicine, USA
Genomic Management of Anti-Platelet Therapeutics

Y.T. Chen, Duke University, USA
Realizing the Promise of Personalized Medicine: HLA-B*1502 Screen in Preventing Carbamazepine-Induced Toxic Effects

Keith J. Johnson, Novartis Institutes for BioMedical Research, Inc., USA
Pharmacogenetic Applications to Enable Drug Development for General Medicine Indications

Federico Innocenti, University of North Carolina at Chapel Hill, USA
Pharmacogenetics of Cancer Therapeutics: Focus on the Germline Genome

Shannon Gibson, University of Toronto, Canada
Short Talk: Ethical, Legal and Social Issues in Pharmacogenomics: A Qualitative Study of the Perspectives of Canadian Stakeholders

15:00—15:30
Coffee Available

Foyer/Hyllan
15:30—17:30
Personalized Genomes
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

B 1-2
* Howard J. Jacob, Medical College of Wisconsin, USA

Michael Snyder, Stanford University School of Medicine, USA
Adventures in Personal Genomics: iPOP of Healthy and Disease States

William A. Gahl, NHGRI, National Institutes of Health, USA
Whole Exome Sequencing for Undiagnosed Diseases

Alan H. Bryce, Mayo Clinic, USA
Short Talk: A Pilot Study of Whole Genome, Whole Exome and RNA Sequencing with CLIA Validation to Identify Potential Therapeutic Targets in Advanced Cancer Patients

George M. Church, Harvard Medical School, USA
The Personal Genome Project and the Future of Medicine

17:30—18:30
Social Hour w/ Lite Bites

Atrium/Foyer
18:30—21:00
Poster Session 2

B3

THURSDAY, JUNE 20

07:30—08:30
Breakfast

Individual Hotel
08:30—11:30
Policy
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

B 1-2
* Janet Woodcock, US Food and Drug Administration, USA

Susanne B. Haga, Duke University, USA
Introducing Genomics in the Clinic: Development of New Delivery Systems

Laura Lyman Rodriguez, NHGRI, National Institutes of Health, USA
Bringing Genomics into Medicine: Advancing the Policy Agenda

Andelka M. Phillips, University of Oxford, UK
Short Talk: We Agree to Sequence your Genomic Data, and you Agree to X, Y, Z…

Katherine Payne, University of Manchester, UK
Quantifying the Economic Value of Personalized Medicine

Jane Kaye, University of Oxford, UK
Privacy, Data-Sharing Frameworks, Global Governance and Translational Research

09:50—10:10
Coffee Break

Foyer/Hyllan
 
On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Foyer/Hyllan
17:00—19:00
Translating Biomarkers to Personalized Medicine
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

B 1-2
* Geoffrey S. Ginsburg, Duke University, USA

Michelle Penny, Eli Lilly and Company, USA
Integration of Genomic Technologies into Drug Discovery and Development

Johan Lundin, University of Helsinki, Finland
Developing Diagnostics from Biomarkers

Thomas Metcalfe, Oncotest GmbH - Institute for Experimental Oncology, Germany
Co-Development of Therapeutics and Companion Diagnostics

19:00—20:00
Social Hour w/ Lite Bites

Atrium/Foyer
20:00—23:00
Entertainment

B 1-3

FRIDAY, JUNE 21

 
Departure


*Session Chair †Speaker invited, not yet responded.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

AstraZeneca Boehringer Ingelheim Pharmaceuticals, Inc.
H3 Biomedicine Inc. Nestlé Institute of Health Sciences
Onyx Pharmaceuticals, Inc. Science for Life Laboratory - Stockholm
Knut and Alice Wallenberg Foundation
 

We gratefully acknowledge additional support for this conference from:


Science Translational Medicine


We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Novartis Institutes for BioMedical Research


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

S. Karger AG - ISCN 2013

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Amanda Deem, Assistant Director of Development, Email: AmandaD@keystonesymposia.org,
Phone:+1 970-262-2668

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676