Registered Attendees

Registered Attendees

Print This Page

Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online before the meeting...these abstracts will be available in the Abstract Book at the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

Close Window
Hilton Santa Fe Historic Plaza Hotel Floorplan

Hilton Santa Fe Historic Plaza Hotel Floorplan

Print This Page

Close Window
This meeting will be conducted in English.

All programs are subject to change. Check this site for updates.

Download Flyer

Twitter hashtag for this meeting: #KSsirtuin

Biology of Sirtuins (C3)

Scientific Organizers: Raul Mostoslavsky, Shin-ichiro Imai, Marcia C. Haigis, Eric M. Verdin

March 8—12, 2015

Hilton Santa Fe Historic Plaza Hotel, Santa Fe, New Mexico, USA

Supported by the Directors' Fund

Abstract submission is closed. Registered attendees can bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email if you are interested. DEADLINES:
Scholarship Deadline: Nov 6, 2014 [details]
Discounted Abstract Deadline: Nov 6, 2014 [details]
Abstract Deadline: Dec 9, 2014 [details]
Discounted Registration Deadline: Jan 8, 2015 [details]

Register Yourself Deadlines and Fees
Deadlines and Fees for 2015-C3 ''Biology of Sirtuins''
Print This Page

Rates and Deadlines listed below are for the 2015-C3 "Biology of Sirtuins" conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details
Before and On November 6, 2014 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details
After November 6, 2014 until January 8, 2015 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
More details
November 6, 2014 n/a
Discounted NON-STUDENT Registration
More details
Before and On January 8, 2015 725.00 USD
(includes 150.00 discount)
Regular NON-STUDENT Registration
More details
After January 8, 2015 875.00 USD
Discounted STUDENT Registration
More details
Before and On January 8, 2015 500.00 USD
(includes 150.00 discount)
Regular STUDENT Registration
More details
After January 8, 2015 650.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will    accept no liability for money loss through bank charges, transfers or currency fluctuations.

Close Window

About Discounted Abstract Deadline
About Global Health Travel Award Deadline
About Scholarship Deadline
About Abstract Deadline
About Discounted Registration Deadline
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


Arrival and Registration

Welcome Mixer
No registration fees are used to fund alcohol served at this function.



Keynote Address
Registered attendees can view abstracts starting on 02/08/2015

John M. Denu, University of Wisconsin-Madison, USA
Life and Times in the Sirtuin Field

Sirtuins in Metabolism and Signaling Pathways
Registered attendees can view abstracts starting on 02/08/2015

David B. Lombard, University of Michigan, USA
Roles for the Sirtuin SIRT5 in Tumor Metabolism

Pere Puigserver, Dana-Farber Cancer Institute, Harvard Medical School, USA
Differential Regulation of PGC1a by Multiple Sirtuins

* Shin-ichiro Imai, Washington University School of Medicine, USA
The NAD World Reloaded: The Importance of the Inter-Tissue Communication Mediated by NAMPT/NAD+/SIRT1 in Mammalian Aging/Longevity Control

Charles Brenner, University of Iowa, USA
Short Talk: How Nicotinamide Riboside Promotes Weight Loss

Joseph A. Garcia, University of Texas Southwestern Medical Center, USA
Short Talk: An Acetate Switch Links Dynamic Changes in Intermediary Metabolism with Stress Signaling in Mammals

Coffee Break

Poster Setup

Poster Viewing

On Own for Lunch

Coffee Available

Biochemistry and Structure of Sirtuins
Registered attendees can view abstracts starting on 02/08/2015

* John M. Denu, University of Wisconsin-Madison, USA

Stephen L. Helfand, Brown University, USA
Sirtuins in the Fly: Effect on Mitochondria, Gene Regulation and Chromatin Maintenance Controls Metabolism and Longevity

David A. Sinclair, Harvard Medical School, USA
Evidence for an Epigenetic Cause of Aging and Age-Related Diseases

Hening Lin, Cornell University, USA
Sirtuin Inhibitors as Anticancer Agents

Clemens Steegborn, University of Bayreuth, Germany
Short Talk: Novel Substrates and Inhibitors for Sirtuins 4 and 5 through Structural, Biochemical and Mass Spectrometry Studies

Lulu A. Cambronne, Oregon Health & Sciences University, USA
Short Talk: A Genetically-Encoded Fluorescent NAD+ Sensor

Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Poster Session 1



Poster Setup

Poster Viewing

Sirtuins and Cancer
Registered attendees can view abstracts starting on 02/08/2015

* Raul Mostoslavsky, Massachusetts General Hospital, Harvard Medical School, USA
Linking Epigenetics, Metabolism and Cancer: SIRT6 Provides Some Clues

Michael Ristow, ETH Z├╝rich, Switzerland
Mitohormesis: How Reactive Oxygen Species (ROS) Promote Healthspan

Marcia C. Haigis, Harvard Medical School, USA
New Roles for Sirtuins in Mitochondrial Homeostasis

David Gius, Northwestern University Feinberg School of Medical, USA
Short Talk: Loss of SIRT3 Activity and MnSOD Acetylation Results in Endocrine Breast Tumor Cell Resistance

Berta N. Vazquez, Rutgers University, USA
Short Talk: SIRT7 Promotes Genome Integrity by Regulating Non-Homologous End Joining DNA Repair

Marty W. Mayo, University of Virginia, USA
Short Talk: NAD+-Dependent Deacetylases SIRT1 and SIRT2 Regulate the Mitogen-Activated Protein Kinase Kinase (MEK)-1 Alternative Pathway

Christina M. Ferrer, Drexel University College of Medicine, USA
Short Talk: O-GlcNAcylation Regulates Breast Cancer Cell Invasion via the NAD+-Dependent Deacetylase SIRT1

Coffee Break


Poster Session 2

Workshop: Emerging Concepts in Sirtuin Biology

* David A. Sinclair, Harvard Medical School, USA

Matthew D. Hirschey, Duke University, USA
Chemical Reactivity and Novel Post-Translational Modifications Regulated by Mitochondrial Sirtuins

Zhen Tong, Cornell University, USA
SIRT7 Regulates the Activation of RALA via Defatty-Acylation

Natalie E. de Picciotto, University of Colorado Boulder, USA
SIRT1 Activation with Nicotinamide Mononucleotide Improves Vascular Function in Old Male Mice

Mark Y. Jeng, University of California, San Francisco, USA
Loss of SIRT1 Mediates Metabolic Reprogramming in Memory T Cells during Aging and Chronic Infections

Pavlos Pissios, Beth Israel Deaconess Medical Center, USA
Nicotinamide N-Methyltransferase Regulates Hepatic Nutrient Metabolism through N1-Methylnicotinamide

X. Charlie Dong, Indiana University School of Medicine, USA
Sirt6 Regulates Insulin Secretion from the Pancreatic Beta Cells

Alison E. Ringel, Johns Hopkins University, School of Medicine, USA
Alternate Deacylating Specificities for the Archaeal Sirtuins Sir2Af1 and Sir2Af2

Coffee Available

Sirtuins and Mitochondrial Biology
Registered attendees can view abstracts starting on 02/08/2015

* Eric M. Verdin, University of California, San Francisco, USA
SIRT1, CD4 T Cell Subsets and Autoimmunity

Brian K. Kennedy, Buck Institute for Research on Aging, USA
Sirtuins and mTOR as Modulators of Metabolic Responses

Hiroshi Itoh, Keio University School of Medicine, Japan
Sirt1 Function in Kidney

Joseph T. Bass, Northwestern University, USA
Circadian Rhythms in Mitochondrial Function

On Own for Dinner



Sirtuins, Neurobiology and Neurodegeneration
Registered attendees can view abstracts starting on 02/08/2015

Leonard P. Guarente, Massachusetts Institute of Technology, USA
Sirtuins, NAD and Aging

* Ruth Luthi-Carter, University of Leicester, UK
Sirtuins as Therapeutic Targets Against Neurodegeneration

Katrin F. Chua, Stanford University Medical Center, USA
Chromatin Regulation and Genome Maintenance by Mammalian SIRT6 and SIRT7

Lindsey B. Gano, University of Colorado, Anschutz Medical Campus, USA
Short Talk: SIRT3 Dysfunction in Experimental Temporal Lobe Epilepsy

Tatyana Gudz, Medical University of South Carolina, USA
Short Talk: SIRT3-Mediated Deacetylation of Ceramide Synthase Promotes Mitochondrial Dysfunction and Brain Injury after Stroke

Colleen A. Stoyas, University of California, San Diego, USA
Short Talk: Does Sirt1 Dysregulation Contribute to Pathogenesis of the Neurodegenerative Disorder Spinocerebellar Ataxia Type 7?

Coffee Break

On Own for Lunch

Coffee Available

Sirtuins as Targets for Therapeutic Purposes
Registered attendees can view abstracts starting on 02/08/2015

* Marcia C. Haigis, Harvard Medical School, USA

James L. Ellis, GlaxoSmithKline, USA
Sirtuin Modulators as Therapeutic Agents for Metabolic and Inflammatory Diseases

Eriko Michishita-Kioi, Daiichi Sankyo Co., Ltd., Japan
Targeting Metabolic Enzymes

Yousin Suh, Albert Einstein College of Medicine, USA
Molecular Mechanisms Underlying SIRT1 Disease Risk Variants

Xiaoling Li, NIEHS, National Institutes of Health, USA
SIRT1 in Metabolism, Tissue Homeostasis and Human Diseases

Manfred Jung, University of Freiburg, Germany
Short Talk: Selective Inhibition of the NAD-Dependent Histone Deacetylase hSirt2 by Ligand-Induced Rearrangement of the Active Site

Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.



*Session Chair †Invited, not yet responded.

We gratefully acknowledge support for this conference from:

Directors' Fund

These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.

We gratefully acknowledge the generous grant for this conference provided by:

National Institutes of Health

Grant No. 1R13AG049581-01

Funding for this conference was made possible, in part by Grant # 1R13AG049581-01 from the National Institute on Aging. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Assistant Director of Development, Email:,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email:,
Phone:+1 970-262-2676