Clarion Hotel Sign Floorplan
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This meeting took place in 2016
Here are the related meetings in 2018:
B Cells: Mechanisms in Immunity and Autoimmunity (E4)
For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.
B Cells at the Intersection of Innate and Adaptive Immunity (E3)
Organizer(s) Mikael C. I. Karlsson, Claudia Mauri, Eric Meffre and Andrea Cerutti
May 29—June 2, 2016
Clarion Hotel Sign • Stockholm, Sweden
Discounted Abstract Deadline: Jan 28, 2016
Abstract Deadline: Feb 29, 2016
Scholarship Deadline: Jan 28, 2016
Discounted Registration Deadline: Mar 29, 2016
Sponsored by AbbVie Inc. and BioLegend, Inc.
Summary of Meeting:
In the last few years, the role of B cells in the innate immune response and effector functions beyond antibody production has started to be appreciated. This meeting puts emphasis on newly discovered roles of B cells and discusses novel concepts in B cell biology that will open new venues to design B cell-directed treatments. It will thus highlight the function of B cells as general responders and regulators of inflammation and contrast this to their function and latest discoveries of their role as antibody producers.
View Scholarships/Awards
In the last few years, the role of B cells in the innate immune response and effector functions beyond antibody production has started to be appreciated. This meeting puts emphasis on newly discovered roles of B cells and discusses novel concepts in B cell biology that will open new venues to design B cell-directed treatments. It will thus highlight the function of B cells as general responders and regulators of inflammation and contrast this to their function and latest discoveries of their role as antibody producers.
View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference
The meeting will begin on Sunday, May 29 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, June 2 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, June 3 in order to fully experience the meeting.
SUNDAY, MAY 29
MONDAY, MAY 30
TUESDAY, MAY 31
WEDNESDAY, JUNE 1
THURSDAY, JUNE 2
FRIDAY, JUNE 3
Conference Program Print | View meeting in 12 hr (am/pm) time
The meeting will begin on Sunday, May 29 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, June 2 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, June 3 in order to fully experience the meeting.
SUNDAY, MAY 29
08:30—09:30
Welcoming Remarks and Keynote Address
Meeting has ended...abstracts no longer viewable online.
*
Michel C. Nussenzweig,
HHMI/Rockefeller University, USA
Klaus Rajewsky,
Max Delbrück Center for Molecular Medicine, Germany
Struggle for Life in the B Cell World
Struggle for Life in the B Cell World
09:30—12:00
Creating and Maintaining the B Cell Repertoire
Meeting has ended...abstracts no longer viewable online.
*
Eric Meffre,
Yale University School of Medicine, USA
*
Tomohiro Kurosaki,
WPI Immunology Frontier Research Center, Osaka University, Japan
Meinrad Busslinger,
Research Institute of Molecular Pathology, Austria
Transcriptional Control of Late B Cell Development
Transcriptional Control of Late B Cell Development
Marcus R. Clark,
University of Chicago, USA
BRWD1 Orchestrates Ig-kappa Recombination and Late B Cell Development
BRWD1 Orchestrates Ig-kappa Recombination and Late B Cell Development
Trine A. Kristiansen,
Lund University, Sweden
Short Talk: Cellular Barcoding Links B-1a B Cell Potential to a Reversible Fetal Hematopoietic Stem Cell State at the Clonal Level
Short Talk: Cellular Barcoding Links B-1a B Cell Potential to a Reversible Fetal Hematopoietic Stem Cell State at the Clonal Level
Luka Mesin,
Whitehead Institute, USA
Short Talk: Visualizing Clonal Selection in Germinal Centers
Short Talk: Visualizing Clonal Selection in Germinal Centers
14:30—16:30
Workshop 1
*
Deborah Dunn-Walters,
University of Surrey, UK
*
Michael P. Cancro,
University of Pennsylvania, USA
Kathrin Pieper,
Institute for Research in Biomedicine, Switzerland
A New Mechanism of Immunoglobulin Diversification Generates Broadly Reactive Antibodies to Plasmodium Falciparum
A New Mechanism of Immunoglobulin Diversification Generates Broadly Reactive Antibodies to Plasmodium Falciparum
Caroline Rönnberg,
Karolinska Institutet Solna, Sweden
A Prospective Study of B Cell Dynamics in Patients with Malaria using Mass Cytometry
A Prospective Study of B Cell Dynamics in Patients with Malaria using Mass Cytometry
Amit Saxena,
Karolinska Institutet, Sweden
Reactive Oxygen Species Control Autoreactive B Cell Tolerance in a Mouse Model of Rheumatoid Arthritis
Reactive Oxygen Species Control Autoreactive B Cell Tolerance in a Mouse Model of Rheumatoid Arthritis
S. Rameeza Allie,
University of Alabama, Birmingham, USA
Identification of Germinal Center Dependent, Lung Resident Memory B Cells after Influenza infection
Identification of Germinal Center Dependent, Lung Resident Memory B Cells after Influenza infection
Kristine Oleinika,
University College London, UK
Regulatory B Cells Control Inflammation through the Induction of Suppressive Invariant Natural Killer T Cells
Regulatory B Cells Control Inflammation through the Induction of Suppressive Invariant Natural Killer T Cells
Marta E. Alarcón Riquelme,
GENYO. Center for Genomics and Oncological Research, Spain
BANK1 Controls IgG Class Switching Through TLR7-Dependent STAT1 Activation
BANK1 Controls IgG Class Switching Through TLR7-Dependent STAT1 Activation
Peter P. Bönelt,
Research Institute of Molecular Pathology, Austria
Autoimmunity Caused by Premature Blimp1 Expression during B Cell Development
Autoimmunity Caused by Premature Blimp1 Expression during B Cell Development
17:00—19:00
Innate B Cell Activation
Meeting has ended...abstracts no longer viewable online.
*
Mikael C. I. Karlsson,
Karolinska Institutet, Sweden
*
Gunilla B. Karlsson Hedestam,
Karolinska Institutet, Sweden
Andrea Cerutti,
Mount Sinai School of Medicine, USA
Innate Signaling Networks in B Cell Activation
Innate Signaling Networks in B Cell Activation
John F. Kearney,
University of Alabama, Birmingham, USA
Effects of Neonatal Microbial Exposure on B Cell Development and Protection Against Allergic and Autoimmune Disease
Effects of Neonatal Microbial Exposure on B Cell Development and Protection Against Allergic and Autoimmune Disease
Mikael C. I. Karlsson,
Karolinska Institutet, Sweden
Short Talk: Neutrophils License NKT Cells to Regulate Self-Reactive B Cell Responses
Short Talk: Neutrophils License NKT Cells to Regulate Self-Reactive B Cell Responses
Lieselotte Sarah Maria Kreuk,
University of California, Berkeley, USA
Short Talk: Characterizing the Ontogeny and Downstream Immunological Significance of Anti-Commensal IgG with the Use of an IgG3 Reporter Mouse
Short Talk: Characterizing the Ontogeny and Downstream Immunological Significance of Anti-Commensal IgG with the Use of an IgG3 Reporter Mouse
Andrew Getahun,
University of Colorado School of Medicine, USA
Short Talk: Continuous Inhibitory Signaling by Both SHP-1 and SHIP-1 Pathways is Required to Maintain Unresponsiveness of Autoreactive B Cells
Short Talk: Continuous Inhibitory Signaling by Both SHP-1 and SHIP-1 Pathways is Required to Maintain Unresponsiveness of Autoreactive B Cells
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:30—11:30
B Cell Subsets
Meeting has ended...abstracts no longer viewable online.
*
Thomas L. Rothstein,
Western Michigan University, USA
*
Joan Yuan,
Lund University, Sweden
Marc K. Jenkins,
University of Minnesota Medical School, USA
Tracking Protein Antigen-specific Memory B Cells
Tracking Protein Antigen-specific Memory B Cells
Jean-Claude Weill,
Institut Necker-Enfants Malades, INSERM U1151, France
Mouse B Cell Memory Responses to External or Internal Challenges
Mouse B Cell Memory Responses to External or Internal Challenges
Bart N. Lambrecht,
VIB, Ghent University, Belgium
New Insights in Marginal Zone B Cell Development by Analysis of Taok3 Deficient Mice
New Insights in Marginal Zone B Cell Development by Analysis of Taok3 Deficient Mice
Lars Nitschke,
University of Erlangen, Germany
Short Talk: Siglec-G, an Inhibitory Receptor on B Cells
Short Talk: Siglec-G, an Inhibitory Receptor on B Cells
14:30—16:30
Workshop 2
*
Lisa Westerberg,
Karolinska Institutet, Sweden
*
Troy D. Randall,
University of Alabama at Birmingham, USA
Heike Schmitt,
Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany
Siglec-H Protects from (Herpes-) Virus Triggered Severe Systemic Autoimmunity
Siglec-H Protects from (Herpes-) Virus Triggered Severe Systemic Autoimmunity
Edina Andrea Schweighoffer,
Francis Crick Institute - Mill Hill Laboratory, UK
BCR – TLR Crosstalk in the LPS Response of B Cells
BCR – TLR Crosstalk in the LPS Response of B Cells
Gabriel Kristian Pedersen,
Karolinska Institutet, Sweden
TACI Expression is Impaired in the Absence of Functional IkappaBNS
TACI Expression is Impaired in the Absence of Functional IkappaBNS
Kai-Ting Chuang Shade,
Massachusetts General Hospital, USA
A Single Glycan on IgE is Indispensable for Initiation of Anaphylaxis
A Single Glycan on IgE is Indispensable for Initiation of Anaphylaxis
Vera Greiner,
Dana-Farber Cancer Institute, USA
Genome Editing of the Human B Cell Receptor with CRISPR/Cas9
Genome Editing of the Human B Cell Receptor with CRISPR/Cas9
Jourdan K. Posner,
University of Hawaii, Manoa, USA
Pattern Recognition Receptor Ligands Drive the Differentiation and Activation of Human B Cell Subsets
Pattern Recognition Receptor Ligands Drive the Differentiation and Activation of Human B Cell Subsets
Soren E. Degn,
Harvard Medical School, USA
Autoreactive Germinal Center Dynamics and the Evolution of Autoreactive B Cells
Autoreactive Germinal Center Dynamics and the Evolution of Autoreactive B Cells
17:00—19:15
B Cell Tolerance
Meeting has ended...abstracts no longer viewable online.
*
Ann Marshak-Rothstein,
University of Massachusetts Medical School, USA
*
Frances E. Lund,
University of Alabama at Birmingham, USA
Eric Meffre,
Yale University School of Medicine, USA
Resetting Early B Cell Tolerance Checkpoints Defective in Patients with Autoimmune Diseases
Resetting Early B Cell Tolerance Checkpoints Defective in Patients with Autoimmune Diseases
Christopher Sundling,
Garvan Institute of Medical Research, Australia
Plasma Cell Differentiation from Conventional and Rogue GC B Cells
Plasma Cell Differentiation from Conventional and Rogue GC B Cells
Michael P. Cancro,
University of Pennsylvania, USA
Age Associated B Cells: T-bet Driven Effectors of Protective and Autoimmune Responses
Age Associated B Cells: T-bet Driven Effectors of Protective and Autoimmune Responses
David J. Rawlings,
University of Washington, Seattle Children's Hospital Research Institute, USA
B Cell-Intrinsic Signals Critical for T Cell-Dependent vs. Independent Loss of Tolerance
B Cell-Intrinsic Signals Critical for T Cell-Dependent vs. Independent Loss of Tolerance
19:15—20:15
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:30—11:45
Antibody Effector Functions and Antigen Recognition by the BCR
Meeting has ended...abstracts no longer viewable online.
*
Lill Martensson,
University of Gothenburg, Sweden
*
Birgitta Heyman,
Uppsala University, Sweden
Michel C. Nussenzweig,
HHMI/Rockefeller University, USA
The Germinal Center Reaction
The Germinal Center Reaction
Maureen McGargill,
St Jude Children's Research Hospital, USA
Generation of Antibodies to Conserved Influenza A Epitopes
Generation of Antibodies to Conserved Influenza A Epitopes
Tak W. Mak,
Campbell Family Institute for Breast Cancer, Canada
The IgM Fc-Receptor
The IgM Fc-Receptor
Jeffrey V. Ravetch,
Rockefeller University, USA
Diversification of Antibody Effector Function
Diversification of Antibody Effector Function
Michael Reth,
Albert-Ludwigs University Freiburg, Germany
Molecular Requirements for the Sensing of Monovalent Antigens by the Oligomeric B cell Antigen Receptor
Molecular Requirements for the Sensing of Monovalent Antigens by the Oligomeric B cell Antigen Receptor
14:30—16:30
Workshop 3
*
Lars Nitschke,
University of Erlangen, Germany
*
Stephen Malin,
Karolinska Institute, Sweden
Feng Feng,
Boston University, USA
An Autoreactive Memory-Derived Plasmablast Response Precedes the Immunogen-Specific Response in the Repeated Anthrax Vaccine in Humans
An Autoreactive Memory-Derived Plasmablast Response Precedes the Immunogen-Specific Response in the Repeated Anthrax Vaccine in Humans
Hermann Eibel,
University Medical Center Freiburg, Germany
Differential Signaling and Processing of BAFF-Receptor in B Cells
Differential Signaling and Processing of BAFF-Receptor in B Cells
Tam Quách,
NSLIJ The Feinstein Medical Research Institute, USA
Human B-1 And B-2 Cells Come From A Lin-CD34+CD38lo Progenitor Population
Human B-1 And B-2 Cells Come From A Lin-CD34+CD38lo Progenitor Population
Selina Keppler,
Francis Crick Institute, UK
WIP-ing B cells: CD19 as a Generic Hub for PI3K Signaling
WIP-ing B cells: CD19 as a Generic Hub for PI3K Signaling
Hedda Wardemann,
German Cancer Research Center, Germany
Clonal Selection of Memory B Cells Upon Human Malaria Infection
Clonal Selection of Memory B Cells Upon Human Malaria Infection
Almudena R. Ramiro,
Centro Nacional de Investigaciones Cardiovasculares, Spain
Non-Hodgkin Lymphoma Therapeutics by MicroRNA-28 Replacement
Non-Hodgkin Lymphoma Therapeutics by MicroRNA-28 Replacement
Patricia J. Gearhart,
NIA, National Institutes of Health, USA
DNA Breaks in Variable Regions Are Predominantly Single Stranded and Generated by UNG and MSH6 Pathways
DNA Breaks in Variable Regions Are Predominantly Single Stranded and Generated by UNG and MSH6 Pathways
17:00—19:15
Mucosal B Cell Responses
Meeting has ended...abstracts no longer viewable online.
*
Andrea Cerutti,
Mount Sinai School of Medicine, USA
*
Eduardo J. Villablanca,
Karolinska Institute, Sweden
Jeffrey J. Bunker,
University of Chicago, USA
Specificity of IgA Responses
Specificity of IgA Responses
Sergei A. Nedospasov,
Engelhardt Institute of Molecular Biology, Russia
ILC3, IgA, Cytokines and Beyond
ILC3, IgA, Cytokines and Beyond
Claudia Berek,
Deutsches Rheuma Forschungszentrum, Germany
A Key Role of Eosinophils for the Normal Organization of the Gut Immune Compartment
A Key Role of Eosinophils for the Normal Organization of the Gut Immune Compartment
Duane R. Wesemann,
Brigham and Women's Hospital, Harvard Medical School, USA
Short Talk: Microbes Regulate Primary Ig Repertoire Polyreactivity
Short Talk: Microbes Regulate Primary Ig Repertoire Polyreactivity
Yang Yang,
Stanford University School of Medicine, USA
Short Talk: Distinct Mechanisms Define Murine B Cell Lineage Immunoglobulin Heavy Chain (IgH) Repertoires
Short Talk: Distinct Mechanisms Define Murine B Cell Lineage Immunoglobulin Heavy Chain (IgH) Repertoires
19:15—20:15
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:30—11:30
B Cells as Regulators of the Immune Response
Meeting has ended...abstracts no longer viewable online.
*
Paolo Casali,
University of Texas School of Medicine, USA
Frances E. Lund,
University of Alabama at Birmingham, USA
Cytokine-Dependent Induction of Novel Human Plasma Cell Precursors in Autoimmune Mice and Humans
Cytokine-Dependent Induction of Novel Human Plasma Cell Precursors in Autoimmune Mice and Humans
*
Claudia Mauri,
University College London, UK
Generation of Systemic and Mucosal B Regulatory Cells
Generation of Systemic and Mucosal B Regulatory Cells
Michael C. Carroll,
Boston Children's Hospital, Harvard Medical School, USA
Maintenance of Self-Reactive Memory B Cells by FDC
Maintenance of Self-Reactive Memory B Cells by FDC
Yi Hao,
Huazhong University of Science & Technology, China
Short Talk: Persistent Germinal Centers and Circulating Antigen-Specific Antibodies Modulate B Cell Memory Responses
Short Talk: Persistent Germinal Centers and Circulating Antigen-Specific Antibodies Modulate B Cell Memory Responses
Kai Kisand,
University of Tartu, Estonia
Short Talk: High-Affinity Disease-Ameliorating Autoantibodies in Patients with Defective Central T Cell Tolerance
Short Talk: High-Affinity Disease-Ameliorating Autoantibodies in Patients with Defective Central T Cell Tolerance
Melissa Marie Walker,
University of Colorado, USA
Short Talk: Cyclic-di-Nucleotides as STING-Dependent Adjuvants and B Cell Activators
Short Talk: Cyclic-di-Nucleotides as STING-Dependent Adjuvants and B Cell Activators
17:00—18:45
Targeting B Cells for Treatment
Meeting has ended...abstracts no longer viewable online.
*
Kristina Lejon,
Umeå University, Sweden
*
Elizabeth A. Leadbetter,
University of Texas Health Science Center, USA
Simone Cenci,
University Vita Salute Fondazione Centro San Raffaele del M.te Tabor, Italy
Autophagy in Plasma Cell Pathophysiology
Autophagy in Plasma Cell Pathophysiology
Antonio Lanzavecchia,
Institute for Research in Biomedicine, Switzerland
Broadly Neutralizing Antibodies and a New Mechanism of Diversification
Broadly Neutralizing Antibodies and a New Mechanism of Diversification
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.
*Session Chair †Invited, not yet responded.
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