Daejeon Convention Center Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

This meeting took place in 2019


Here are the related meetings in 2020:
Noncoding RNAs: Mechanism, Function and Therapies (A1)

For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Small Regulatory RNAs (D7)


Organizer(s) V. Narry Kim, Gregory J. Hannon, Lin He and Victor Ambros
April 14—18, 2019
Daejeon Convention Center • Daejeon, South Korea
Discounted Abstract Deadline: Dec 19, 2018
Abstract Deadline: Jan 16, 2019
Scholarship Deadline: Dec 19, 2018
Discounted Registration Deadline: Feb 13, 2019

Developed in collaboration with the Institute for Basic Science

Supported by the Directors' Fund

Summary of Meeting:
Small regulatory RNAs are integral players in eukaryotic gene regulation, and are involved in numerous developmental and pathological pathways. Although the field has been making remarkable progress in recent years, it still has a number of seminal questions. We need to understand how cell, pathways are connected to small RNA pathways, how small RNAs are regulated and function during cell fate transition, how small RNAs interact with subcellular compartments, if and how they are transported between cells, and how small RNAs participate in immune response. We also need to gain a systemic view of small RNAs and their targets in the context of gene network, and to understand their involvements in human diseases, not just cancer but also in other genetic and metabolic disorders. At this conference, we aim to bring together scientists studying diverse animal and plant model organisms, which will offer an opportunity to understand the mechanism and function of small RNAs in evolutionary and physiological context. This conference will also bridge the gaps between fundamental knowledge, clinical needs, and technical development, by addressing issues such as small RNA involvement in diseases, in vivo delivery of RNA, and technical challenges in RNA detection at single-molecule and single-cell levels. Compared with other conferences on RNA, this conference is unique in that it focuses on small regulatory RNAs, yet it is highly diverse in research approaches and biological systems. This conference will serve as a central forum for small RNA community.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Sunday, April 14 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, April 18 with a closing plenary session from 17:00 to 19:15, followed by a social hour and entertainment. We recommend return travel on Friday, April 19 in order to fully experience the meeting.

SUNDAY, APRIL 14

16:00—20:00
Arrival and Registration

2nd Floor Lobby
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

2nd Floor Lobby/Terrace

MONDAY, APRIL 15

08:00—08:30
Poster Setup

Room 202
08:30—19:00
Poster Viewing

Room 202
08:30—08:45
Welcome and Memorial Speech for Elisa Izaurralde
Meeting has ended...abstracts no longer viewable online.

Room 201
* V. Narry Kim, Institute for Basic Science, South Korea

Oliver Weichenrieder, Max Planck Institute for Developmental Biology, Germany

08:45—09:45
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Room 201
* V. Narry Kim, Institute for Basic Science, South Korea

David P. Bartel, Massachusetts Institute of Technology and Whitehead Institute, USA
MicroRNAs

09:45—11:45
MicroRNA Biogenesis and Turnover
Meeting has ended...abstracts no longer viewable online.

Room 201
* Anastasia Khvorova, University of Massachusetts Medical School, USA

Gunter Meister, University of Regensburg, Germany
Regulation of Gene Expression by RNA-Binding Proteins and Non-Coding RNAs

Coffee Break

Helge Großhans, Friedrich Miescher Institute - FMI, Switzerland
Promoting Adulthood through One miRNA with a Single Target

Eric C. Lai, Sloan Kettering Institute, USA
Short Talk: Genomic Clustering Aids Nuclear Processing of Suboptimal pri-miRNA loci

Daniel Cifuentes, Boston University, USA
Short Talk: A Negative Feedback Loop Between Dicer and miR-144 Dampens Canonical microRNA Biogenesis and Maximizes the Ago2-Dependent Processing of miR-451 during Vertebrate Erythropoiesis

11:45—13:00
Lunch

Room 202
12:00—14:30
Poster Session 1

Room 202
14:30—16:30
Workshop 1

Room 201
* Mofang Liu, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, China

Séverine Chambeyron, Institute of Human Genetics, France
The NuRD Complex Mediates piRNA-Guided Heterochromatin Formation in Metazoans

Caterina Gasperini, Italian Institute of Technology, Italy
Identification of piRNAs and Functional Investigation of piRNA-Pathway in Adult Mammalian Neural Progenitor Cells

Xin Zhiguo Li, University of Rochester Medical Center, USA
Ribosomes Guide Initial piRNA Processing on Long Single Strand Precursor RNAs

Kensaku Murano, Keio University, Japan
Nuclear RNA Export Factor Variant Triggers Piwi-piRNA-Mediated Co-Transcriptional Silencing

Yang Yu, Institute of Biophysics, CAS, China
A Pandas Complex Adapted for piRNA-Guided Transposon Silencing

Dong-Hoon Jeong, Hallym University, South Korea
The Role of Small Regulatory RNAs in Rice Epigenetic Regulation

Seung Cho Lee, Cold Spring Harbor Laboratory, USA
21-22 nt easiRNA-Dependent Regulation of Retrotransposition in Arabidopsis

Yuriki Sakurai, University of Tokyo, Japan
In vitro Recapitulation of the Secondary siRNA Biogenesis in Plants

16:30—17:00
Coffee Available

Foyer
17:00—19:00
MicroRNA Function in Development and Stem Cells
Meeting has ended...abstracts no longer viewable online.

Room 201
* Xuemei Chen, University of California, Riverside, USA

Lin He, University of California, Berkeley, USA
Non-Coding RNAs Regulate Cell Fate Potential in Pluripotent Stem Cells

Anton J. Enright, University of Cambridge, UK
Detection of Subtle microRNA Binding Effects on mRNA Levels using Single-Sum Significance k-mer Analysis

Mollie K. Meffert, Johns Hopkins University School of Medicine, USA
Short Talk: Growth Regulatory miRNAs in Neuronal Function

Aishe Angeletti Sarshad, University of Gothenburg, Sweden
Short Talk: Argonaute-miRNA Complexes Silence Target mRNAs in the Nucleus of Mammalian Stem Cells

19:00
On Own for Dinner
No registration fees are used to fund alcohol served at this function.


TUESDAY, APRIL 16

08:30—11:30
MicroRNA Function in Disease
Meeting has ended...abstracts no longer viewable online.

Room 201
* Mollie K. Meffert, Johns Hopkins University School of Medicine, USA

Stefania Nicoli, Yale University, USA
MicroRNA-223 Limits Hematopoietic Stem Cell Production from the Developing Aorta

Jin Hong Kim, Seoul National University, South Korea
Stress-Activated miR-204 Governs Senescent Phenotypes of Chondrocytes to Promote Osteoarthritis Development

Coffee Break

Rui Yi, University of Colorado Boulder, USA
MicroRNA-Mediated Regulatory Network in Hair Follicle Stem Cells

Jun-An Chen, Academia Sinica, Taiwan
The Role of MicroRNA during Motor Neuron Development and Degeneration

Anna Bludau, University of Regensburg, Germany
Short Talk: Lateral Septum miRNA Alterations in Response to Social Fear Conditioning: Functional Involvement of miR-132 in Extinction and Oxytocin-Mediated Reversal of Social Fear

09:30—09:50
Coffee Break

Foyer
11:30—17:00
On Own for Lunch

13:00—22:00
Poster Viewing

Room 202
14:30—16:30
Meet the Speakers
Space is limited. Please sign-up in advance.

Room 204 + 205
16:30—17:00
Coffee Available

Foyer
17:00—19:00
Small RNAs as Therapeutic and Diagnostic Tools
Meeting has ended...abstracts no longer viewable online.

Room 201
* Phillip D. Zamore, University of Massachusetts Medical School, USA

Anastasia Khvorova, University of Massachusetts Medical School, USA
RNAi-Based Modulation of Gene Expression in Central Nervous System

Karyn Schmidt, Alnylam Pharmaceuticals, USA
Mechanistic Insights and Progress on the GalNAc-siRNA Conjugate Platform for Targeted Delivery of RNAi Therapeutics to the Liver

Bastian Fromm, SciLifeLab - Stockholm
Short Talk: The Metazoan MicroRNA Complement

Yun Sang Cho, Animal and Plant Quarantine Agency, South Korea
Short Talk: Safety and Efficacy of Double Strand RNA against Sacbrood Virus Infection in Apis cerana

Gaspare La Rocca, Memorial Sloan Kettering Cancer Center, USA
Short Talk: Development of a Novel Mouse Model for the Reversible, Temporally and Spatially Controlled Inhibition of miRNA Activity in vivo

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Room 202
19:30—21:30
Poster Session 2

Room 202

WEDNESDAY, APRIL 17

08:30—19:00
Poster Viewing

Room 202
08:30—11:45
Mechanism of RNA Silencing
Meeting has ended...abstracts no longer viewable online.

Room 201
* Mikiko C. Siomi, University of Tokyo, Japan

Xuemei Chen, University of California, Riverside, USA
TREX-2 and A Nuclear Pore Protein in MicroRNA Biogenesis in Arabidopsis

Yukihide Tomari, University of Tokyo, Japan
The 3′-End Formation Mechanism of Silkworm piRNAs

Coffee Break

Phillip D. Zamore, University of Massachusetts Medical School, USA
An Unexpected Function for a Eubacterial Argonaute Protein

Mofang Liu, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, China
Multiple Roles of MIWI/piRNAs in Regulating Spermiogenesis in Mice

Daehyun Baek, Seoul National University, South Korea
Short Talk: Most RNA-Binding Proteins are microRNA Targeting Enhancers

Shu-Huei Hsiao, National Chung Cheng University, Taiwan
Short Talk: Loss of PIWIL4 and L1TD1 Disrupts Somatic piRNA, Methylome and Genome Stability

Larissa Nitschke, Baylor College of Medicine, USA
Short Talk: MicroRNA 760 Regulates the Expression of Atxn1 via Interaction with its 5'untranslated Region

11:45—12:30
Lunch

Room 202
12:30—14:30
Poster Session 3

Room 202
14:30—16:30
Workshop 2

Room 201
* Martin J. Simard, CRCHU de Québec-Université Laval, Canada

Lu Ya-Lin, Washington University in St. Louis, USA
Bifunctional Role of miR-124 during Neuronal Reprogramming of Human Fibroblasts

Tuan Anh Nguyen, Hong Kong University of Science and Technology, Hong Kong
Novel Players Regulate pri-miRNA Processing

Lei Wang, Chinese Academy of Sciences, China
RNA Helicase AQR Cooperates with the DROSHA-DGCR8 Complex to Promote Primary microRNA Processing

Claudia Lang, Plant and Food Research, New Zealand
A Randomized, Controlled, Cross-Over Clinical Study Investigating the Bioavailability of Dietary Fruit microRNAs (miRNAs) in Humans

Bing Yang, National Institute of Health, USA
Identifying Essential mir-35 Targeting Sites in C. elegans

Doowon Huh, Rockefeller University, USA
An Adaptive Stress-Induced tRNA Depletion Response Mediates Codon-Based Translational Repression and Growth Suppression

Jian Lu, Peking University, China
Drosophila tsRNAs Preferentially Suppress General Translation Machinery via Antisense Pairing and Participate in Cellular Starvation Response

16:30—17:00
Coffee Available

Foyer
17:00—19:15
Lessons from CRISPR
Meeting has ended...abstracts no longer viewable online.

Room 201
* Lin He, University of California, Berkeley, USA

Yanli Wang, Chinese Academy of Sciences, China
Class 2 CRISPR-Cas RNA-Guided Endonucleases and Inhibitors

Jin-Soo Kim, Institute for Basic Science, South Korea
CRISPR Genome Editing

Chirlmin Joo, Delft University of Technology, Netherlands
Single-Molecule Analysis of Fast and Accurate Target Recognition by Small RNAs

Dinshaw J. Patel, Memorial Sloan Kettering Cancer Center, USA
Structure-based Mechanistic Insights into CRISPR-Cas Surveillance Complexes

Hidetoshi Hasuwa, Keio University School of Medicine, Japan
Short Talk: PIWIL3 Plays an Important Role in Early Embryogenesis of Golden Hamsters

19:15
On Own for Dinner
No registration fees are used to fund alcohol served at this function.


THURSDAY, APRIL 18

08:30—11:30
Diverse Small RNA Pathways I
Meeting has ended...abstracts no longer viewable online.

Room 201
* Helge Großhans, Friedrich Miescher Institute - FMI, Switzerland

Mikiko C. Siomi, University of Tokyo, Japan
piRNA Biogenesis and Functions in Drosophila

Katalin Fejes-Tóth, California Institute of Technology, USA
The SUMO Ligase Su(var)2-10 Links piRNA-Guided Target Recognition to Chromatin Silencing and Controls Gene Expression via Establishment of H3K9 Trimethylation and Negative Feedback Regulation

Coffee Break

Yijun Qi, Tsinghua University, China
Transcriptional Activation by Small RNAs in Plants

JP T. Ouyang, Johns Hopkins University School of Medicine, USA
Short Talk: Loss of Germ Granule Integrity during the Oocyte-to-Embryo Transition Disrupts Small RNA Homeostasis in Caenorhabditis elegans

Jan Schreier, Institute for Molecular Biology, Germany
Short Talk: A Novel Sperm-Specific Compartment Secures an Argonaute Protein for Paternal Epigenetic Inheritance

Xiaorong Zhang, Chinese Academy of Science, China
Short Talk: Exploring Active RNAi in Mitochondria to Reveal Epistatic Translational Control of mtDNA-Encoded Cytochrome C Oxidase Subunits

11:30—17:00
On Own for Lunch

15:30—16:30
Meet the Editors

Room 204 + 205
Steve Mao, Science, AAAS, USA

Angela K. Eggleston, Nature Publishing Group, USA

16:30—17:00
Coffee Available

Foyer
17:00—18:15
Diverse Small RNA Pathways II
Meeting has ended...abstracts no longer viewable online.

Room 201
* Jun-An Chen, Academia Sinica, Taiwan

Victor R. Ambros, University of Massachusetts, USA
Developmental Regulation and Function of Let-7a microRNA in C. elegans

V. Narry Kim, Institute for Basic Science, South Korea
MicroRNA Arm Switching Regulated by Uridylation

Martin J. Simard, CRCHU de Québec-Université Laval, Canada
Short Talk: microRNAs form Distinct Silencing Complexes to Regulate their Target mRNAs Differently

18:15—19:00
Closing Keynote Address
Meeting has ended...abstracts no longer viewable online.

Room 201
* Victor R. Ambros, University of Massachusetts, USA

Phillip A. Sharp, Massachusetts Institute of Technology, USA
Networks of microRNA in Normal and Cancer Cell States

19:00—19:15
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Meeting has ended...abstracts no longer viewable online.

Room 201
19:15—20:15
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Room 202
20:00—20:30
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Room 202

FRIDAY, APRIL 19

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



Keystone Symposia thanks our Sponsor for generously supporting this meeting:

Institute for Basic Science

We gratefully acknowledge additional support for this conference from:

American Society of Gene & Cell Therapy (ASGCT) Daejeon Metropolitan City
eLife
 

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Nick Dua, Senior Director, Communications, Email: nickd@keystonesymposia.org,
Phone:+1 970-262-1179