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This meeting took place in 2019



For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Functional Neurocircuitry of Feeding and Feeding Disorders (J8)


Organizer(s) Roger D. Cone, Lori M. Zeltser and Matthew R. Hayes
February 10—14, 2019
Fairmont Banff Springs • Banff, AB Canada
Discounted Abstract Deadline: Oct 23, 2018
Abstract Deadline: Nov 8, 2018
Scholarship Deadline: Oct 23, 2018
Discounted Registration Deadline: Dec 11, 2018

Sponsored by Novo Nordisk A/S


Summary of Meeting:
The Keystone Symposia conference on neuronal control of appetite is a well-attended conference that is the leading gathering for scientific exchange among those studying the central control of energy homeostasis. The monogenetic syndromes of obesity in mouse and man played a fundamental role in the development of this field, and hence the field has heavily emphasized the control of feeding in models of obesity. However, many disorders of feeding and energy storage, including anorexia nervosa, disease cachexia, pediatric failure to thrive, Prader-Willi disease and progeria are important untreated medical conditions. The goal of this conference will be to gather world leaders in the neural control of feeding and energy homeostasis, along with leaders in the pathophysiology of feeding and energy homeostasis. There is currently no conference in the field that brings together these disparate groups of scientists. For example, recent annual conferences of the Society for the Study of Ingestive Behavior had few talks on anorexia or cachexia. The 2017 Keystone Symposia conference on Neural Control of Appetite began to expand the biological breadth of feeding behaviors under investigation, and this proposed conference will further broaden this field by covering fundamental advances in the neural circuitry underlying feeding, while including entire sessions devoted to anorexia nervosa, disease cachexia, and feeding disorders across the lifespan. Additionally, while the Keystone conference on Obesity and Adipose Tissue Biology has been heavily focused on the hypothalamic control of homeostatic feeding, this conference will have entire sessions devoted to brainstem and telencephalic control of feeding.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Sunday, February 10 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, February 14 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, February 15 in order to fully experience the meeting.

SUNDAY, FEBRUARY 10

16:00—20:00
Arrival and Registration

Van Horne Foyer
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Van Horne Foyer

MONDAY, FEBRUARY 11

07:00—08:00
Breakfast

Mezzanine 2
08:00—09:00
Welcome and Keynote Address
Meeting has ended...abstracts no longer viewable online.

Van Horne C
* Roger D. Cone, University of Michigan, USA

Richard D. Palmiter, HHMI/University of Washington, USA
Neural Circuitry Underlying Feeding Behavior


Following Session is for Obesity and Adipose Tissue Biology (J7)

08:00—09:00
Welcome and Keynote Address
Meeting has ended...abstracts no longer viewable online.

Van Horne A/B
* Matthias Blüher, University of Leipzig, Germany

Stanley Ulijaszek, Institute of Social and Cultural Anthropology, University of Oxford, UK
Framing Obesity as a Problem

09:00—11:30
Neural Circuitry Underlying Feeding Behavior
Meeting has ended...abstracts no longer viewable online.

Van Horne C
* Gary J. Schwartz, Albert Einstein College of Medicine, USA

Linda Rinaman, Florida State University, USA
Neural Circuits Linking Stress and Feeding

Coffee Break

J. Nicholas Betley, University of Pennsylvania, USA
Circuits Regulating Nutritive Control of Feeding

Matthew R. Hayes, University of Pennsylvania, USA
Role of GLP-1 Signaling

Melanie Maya Kaelberer, Duke University, USA
Short Talk: Sensing Calories in the Gut

Jovana Navarrete, National Institutes of Health, USA
Short Talk: Defined Paraventricular Hypothalamic Populations Exhibit Differential Responses to Food Contingent on Caloric State


Following Session is for Obesity and Adipose Tissue Biology (J7)

09:00—11:30
Drug Discovery/Development in Obesity
Meeting has ended...abstracts no longer viewable online.

Van Horne A/B
* Anne Bouloumié, INSERM, France

* Philipp E. Scherer, University of Texas Southwestern Medical Center, USA

Alan R. Saltiel, University of California, San Diego, USA
Inflammation at the Crossroads of Obesity and Energy Homeostasis

Coffee Break

Heiko Lickert, Institute of Diabetes and Regeneration, Germany
Metabolic Impact on Gut Stem Cell Recruitment and Turnover

Nana Gletsu-Miller, Purdue University, USA
Is Bariatric Surgery a Cure for Obesity?

Sheila Collins, Vanderbilt University Medical Center, USA
Short Talk: Natriuretic Peptide "Clearance" Receptor NPRC in Adipocytes: Mechanism of Action and Consequences on Lipolysis and Thermogenesis

Martin Klingenspor, Technical University of Munich, Germany
Short Talk: A Novel Endocrine Gut–Brown Fat–Brain Axis Controls Satiation

11:30—12:30
Workshop 1: Research Opportunities in Eating Disorders

Van Horne C
Joanna Steinglass, Columbia University Medical Center/NYSPI, USA

Lara Bethke, Klarman Family Foundation, USA

Shirly Pinto, Kallyope, USA

Nathalie Kayadjanian, Foundation for Prader-Willi Research, USA

11:30—17:00
On Own for Lunch

11:30—13:00
Poster Setup

Mezzanine 2
13:00—22:00
Poster Viewing

Mezzanine 2

Following Session is for Obesity and Adipose Tissue Biology (J7)

15:00—16:30
Workshop 1: Targeting Brown Adipose Tissue for Obesity Treatment

Van Horne A/B
* Yu-Hua Tseng, Joslin Diabetes Center/Harvard Medical School, USA

* Jan Nedergaard, Stockholm University, Sweden

Katharina Schnabl, Technical University of Munich, Germany
Screening of Gs-Protein Coupled Receptors in Brown Adipocytes Reveals Adrenocorticotropic Hormone as a Non-Adrenergic Activator of Thermogenesis

Zach Gerhart-Hines, University of Copenhagen, Denmark
The Orphan Receptor, GPR3, Activates Thermogenic Fat and Counteracts Obesity Independent of β-Adrenergic Signaling

Alexandra L. Ghaben, University of Texas Southwestern Medical Center, USA
Insulin Is a Novel Activator of Brown Adipocyte Thermogenesis and Promotes Increased Glucose Substrate Utilization over Lipids

Alexandre Caron, University of Texas Southwestern Medical Center, USA
Journal of Lipid Research Junior Investigator Award: Sympathetic Control of Adipose Endocrine and Metabolic Functions

Ruth Karlina, Helmholtz Zentrum München, Germany
Defining Murine Brown Adipose Tissue Heterogeneity

Hyeonwoo Kim, Dana-Farber Cancer Institute/Harvard Medical School, USA
Irisin Induces Thermogenesis in Fat via Integrin alphaV Receptors

16:30—17:00
Coffee Available

Van Horne Foyer
17:00—19:00
Genetic Disorders of Feeding and Energy Storage
Meeting has ended...abstracts no longer viewable online.

Van Horne C
* Herbert Herzog, Garvan Institute, Australia
Snord116 and its Role in Prader-Willi Syndrome

Atul Chopra, Case Western Reserve University, USA
Human Genetics-Aided Discovery of a New Metabolic Hormone

James Minchin, University of Edinburgh, UK
Short Talk: Leveraging High-Throughput Mutagenesis and Functional in vivo Imaging in Zebrafish to Identify Genetic Regulators of Human Energy Homeostasis

George Stratigopoulos, Columbia University, USA
Short Talk: Ciliary Gene RPGRIP1L Is Required for POMC Neuron Development and Function

Lee S. Weinstein, NIDDK, National Institutes of Health, USA
Short Talk: Mice with MC4R Site Mutation (F51L) Develop Severe Obesity Independent of Gsα/cAMP Signaling


Following Session is for Obesity and Adipose Tissue Biology (J7)

17:00—19:00
Brown/Beige/BRITE Fat Activation and Function
Meeting has ended...abstracts no longer viewable online.

Van Horne A/B
* Barbara Cannon, Stockholm University, Sweden

* Steven E. Shoelson, Harvard Medical School, Joslin Diabetes Center, USA

C. Ronald Kahn, Joslin Diabetes Center and Harvard Medical School, USA
Adipose Tissue MicroRNAs as Novel Adipokines in Regulation of Metabolism

Camilla Charlotte Schéele, University of Copenhagen, Denmark
The Plasticity of Human Brown Adipose Tissue

Kirsi A. Virtanen, Turku University Hospital, University of Turku, Finland
BAT - A Target of Future Weight Loss Strategies

Yu-Hua Tseng, Joslin Diabetes Center/Harvard Medical School, USA
Short Talk: 12-lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat

Rana K. Gupta, University of Texas Southwestern Medical Center, USA
Short Talk: Sorting Out Adipocyte Progenitors and their Roles In Adipose Tissue Remodeling

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Mezzanine 2
19:30—22:00
Poster Session 1

Mezzanine 2

TUESDAY, FEBRUARY 12

07:00—08:00
Breakfast

Mezzanine 2
08:00—11:15
Anorexia Nervosa
Meeting has ended...abstracts no longer viewable online.

Van Horne C
* Timothy Moran, Johns Hopkins University School of Medicine, USA

Janet Treasure, King's College London, UK
Understanding and Treating Anorexia Nervosa

Walter Kaye, University of California, San Diego Health, USA
Are Eating Disorders Really Disorders of Eating?

Coffee Break

Jonathan Coleman, King’s College London, UK
Genome-Wide Association Study of Anorexia Nervosa

Lori M. Zeltser, Columbia University, USA
Identifying Novel Therapeutic Targets for Anorexia Nervosa

Claire J. Foldi, Monash University, Australia
Short Talk: The Interplay Between Reward and Control in Anorexia Nervosa: Insights from a Rat Model

Dan J. Christoffel, Stanford University, USA
Short Talk: Differential Control of Hedonic Feeding by Specific Excitatory Accumbal Inputs

Qingchun Tong, University of Texas Medical School, USA
Short Talk: A Lateral Hypothalamus to Basal Forebrain Neurocircuit Promotes Feeding by Suppressing Responses to Anxiogenic Environmental Cues


Following Session is for Obesity and Adipose Tissue Biology (J7)

08:00—11:15
Adipose Tissue and Immune Cells
Meeting has ended...abstracts no longer viewable online.

Van Horne A/B
* Alan R. Saltiel, University of California, San Diego, USA

* Bruce M. Spiegelman, Harvard Medical School, USA

Anne Bouloumié, INSERM, France
The Adipose Tissue Immune Cells, Beyond Inflammation

Ruth E. Gimeno, Eli Lilly and Company, USA
New Therapeutic Approaches to Weight Loss and Glucose Control

Coffee Break

Tim Julius Schulz, German Institute of Human Nutrition, Germany
Deciphering the Adipocytic Lineage: Stem Cell Biology and Regeneration

Samuel Klein, Washington University School of Medicine, USA
Short Talk: Adipose Tissue Immunometabolism

Shunbun Kita, Graduate School of Medicine, Osaka University, Japan
Short Talk: Stimulated Exosome Secretion by Adiponectin Contributes to Effectiveness of Mesenchymal Stem Cell Transplantation on Pressure Overload Heart Failure Models

Stephen E. Flaherty III, Columbia University, USA
Short Talk: A Lipase-Independent Pathway of Lipid Release and Immune Modulation by Adipocytes via Exosomes

Kathrin Landgraf, University of Leipzig, Germany
Short Talk: The Obesity Susceptibility Gene TMEM18 Regulates Adipogenesis through Direct Activation of PPARG Signalling in vitro and in vivo

11:15—17:00
On Own for Lunch

11:15—13:00
Poster Setup

Mezzanine 2
13:00—22:00
Poster Viewing

Mezzanine 2

Following Session is for Obesity and Adipose Tissue Biology (J7)

15:00—16:30
Workshop 2: White Adipose Tissue Plasticity

Van Horne A/B
* Iichiro Shimomura, Osaka University Graduate School of Medicine, Japan

* Gunnar Mellgren, University of Bergen, Norway

Sagar P. Bapat, University of California, San Francisco, USA
Obesity Dysregulates PPAR𝛾 to Drive Th2 Immunopathology

Clair Crewe, University of Texas Southwestern Medical Center, USA
Adipocyte Oxidative Stress Induces Mitochondrial-Derived Extracellular Vesicle Production to Regulate Systemic Metabolism

Siegfried Ussar, Helmholtz Zentrum Muenchen GmbH, Germany
Asc-1 Regulates White versus Beige Adipocyte Fate in a Stromal Cell Population

Farnaz Shamsi, Joslin Diabetes Center, USA
Deconstructing Adipose Tissue Niche Remodeling using Single Cell RNA-Sequencing

Wenwen Zeng, Tsinghua University, China
Neural Regulation of White Adipose Tissue Plasticity

Keren I. Hilgendorf, Stanford University, USA
Ω3 Fatty Acids Activate Ffar4/Gpr120 to Trigger Adipogenesis via the Primary Cilium

16:30—17:00
Coffee Available

Van Horne Foyer
17:00—19:00
Neural Circuits Underlying Nausea, Emesis, and Aversive Responses
Meeting has ended...abstracts no longer viewable online.

Van Horne C
* Harvey J. Grill, University of Pennsylvania, USA

Samuel N. Breit, St. Vincents Hospital, Australia
The Role of the GDF15-GFRAL in Pathway in Control of Appetite and Energy Homeostasis

Bart C. De Jonghe, University of Pennsylvania, USA
Neurocircuitry of Nausea in Chemotherapy

Zachary A. Knight, University of California, San Francisco, USA
The Neurobiology of Hunger

Paul Sabatini, University of Michigan, USA
Short Talk: Activation of Gfral Neurons Decreases Food Intake

Qi Wu, Baylor College of Medicine, USA
Short Talk: Deciphering a Hindbrain Dopaminergic Neural Circuit Mandatory for the Control of Feeding Behavior


Following Session is for Obesity and Adipose Tissue Biology (J7)

17:00—19:00
Adipose Tissue Heterogeneity
Meeting has ended...abstracts no longer viewable online.

Van Horne A/B
* Francine Côté, INSERM, France

* Rana K. Gupta, University of Texas Southwestern Medical Center, USA

Philipp E. Scherer, University of Texas Southwestern Medical Center, USA
Mechanisms of Adipose Tissue Dysfunction in Obesity

David B. Savage, University of Cambridge, UK
A Lipodystrophic Perspective on Insulin Resistance

Ellen E. Blaak, Maastricht University, Netherlands
Sex Differences in Adipose Tissue Metabolism and Tissue-Specific Insulin Resistance

Mikael Rydén, Karolinska Institutet, Sweden
Adipocyte Function and Development in Subcutaneous and Visceral Fat Depots

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Mezzanine 2
19:30—22:00
Poster Session 2

Mezzanine 2

WEDNESDAY, FEBRUARY 13

07:00—08:00
Breakfast

Mezzanine 2
08:00—11:00
Telencephalic Control of Feeding Behavior
Meeting has ended...abstracts no longer viewable online.

Van Horne C
* Jonathan Dean Hommel, University of Texas Medical Branch, USA

Benjamin R. Arenkiel, Baylor College of Medicine, USA
Excitatory Basal Forebrain Circuits Promote Food Avoidance

* Scott E. Kanoski, University of Southern California, USA
Hippocampal Control of Feeding Behavior

Coffee Break

Mark L. Andermann, Beth Israel Deaconess Medical Center, USA
State-Specific Gating of Motivationally Salient Cues by Midbrain Dopaminergic Inputs to Basal Amygdala

Ivan E. de Araujo, Icahn School of Medicine at Mount Sinai, USA
Vagal Control of Brain Reward Systems

Sarah Stern, Rockefeller University, USA
Short Talk: A Molecularly Defined Insular Cortex to Central Amygdala Circuit Controls Cue-Mediated Overconsumption

Christopher D. Morrison, Pennington Biomedical Research Center, USA
Short Talk: FGF21 Signals Protein Status to the Brain and Adaptively Regulates Food Choice and Metabolism


Following Session is for Obesity and Adipose Tissue Biology (J7)

08:00—11:15
Environment and Obesity
Meeting has ended...abstracts no longer viewable online.

Van Horne A/B
* Christoph Buettner, Mount Sinai School of Medicine, USA

* Kirsi A. Virtanen, Turku University Hospital, University of Turku, Finland

J. Andrew Pospisilik, Van Andel Institute, USA
Epigenetic Underpinnings of Metabolic Disease Heterogeneity

Nathalie Delzenne, Université Catholique de Louvain, Belgium
Dealing with the Gut Microbiota in Obesity

Coffee Break

Bruce A. Bunnell, Tulane University School of Medicine, USA
The Impact of Endocrine Disrupting Chemicals on the Biology of Mesenchyaml Stem Cells

Kristen E. Boyle, University of Colorado School of Medicine, USA
Maternal Obesity and Offspring Adiposity: Clues from Umbilical Cord Mesenchymal Stem Cells

Ashley A. Able, Louisiana State University, USA
Short Talk: Inhibition of H3K9 Methyltransferase, GLP, Promotes Metabolically Healthy Gene Expression in Adipocytes

Alexander S. Banks, Harvard Medical School, USA
Short Talk: CalR: Energy Balance Analysis Made Easy

David Merrick, University of Pennsylvania, USA
Short Talk: Identification of a Mesenchymal Progenitor Cell Hierarchy in Adipose Tissue

11:00—17:00
On Own for Lunch

11:00—13:00
Poster Setup

Mezzanine 2
13:00—22:00
Poster Viewing

Mezzanine 2

Following Session is for Obesity and Adipose Tissue Biology (J7)

15:00—16:30
Workshop 3: Adipose Tissue Heterogeneity

Van Horne A/B
* Patrick Seale, University of Pennsylvania, USA

* Silvia Corvera, University of Massachusetts Medical School, USA

Yu An, University of Texas Southwestern Medical Center, USA
Mitochondrial Dicarboxylate Carrier (SLC25A10), a Regulator of Adipocyte Mitochondrial Function and Obesity

Vicky Wang-wei Tsai, St Vincent’s Hospital and University of New South Wales, Australia
Treatment with GDF15 Reduces the Adiposity and Corrects the Metabolic Dysfunction of Mice with Diet-Induced Obesity

Andrea Galmozzi, The Scripps Research Institute, USA
PGRMC2 Is an Intracellular Heme Chaperone Critical for Adipocyte Function

Olivier Bezy, Pfizer Inc., USA
Contrasting Effects of Acute Versus Chronic Treatment with Urocortin 2 on Diet-Induced Obesity and Insulin Resistance

Rebecca Wafer, University of Edinburgh, UK
In vivo Imaging in Zebrafish Identifies Novel Genetic Regulators of Subcutaneous Fat Levels

Nathalie Boulet, INSERM, France
The Heterogeneity in Progenitor Cell Subsets Contributes to the Intrinsic Remodeling Capacity of Human Fat Depots

16:30—17:00
Coffee Available

Van Horne Foyer
17:00—19:00
Feeding Across the Lifespan
Meeting has ended...abstracts no longer viewable online.

Van Horne C
* Shane T. Hentges, Colorado State University, USA

Sebastien G. Bouret, University of Southern California, USA
Molecular Mechanisms Controlling Development of Hypothalamic Feeding Circuits

Kelly L. Klump, Michigan State University, USA
Developmental Differences in Neurobiological Risk Factors for Binge Eating across Adolescence: Evidence from Animal and Human Models

Susan Carnell, Johns Hopkins University, USA
Childhood Eating Behaviors

Patricia O. Prada, University of Campinas, Brazil
Short Talk: Maternal Exposure to Air Pollution during Lactation Induces Hyperphagia, Obesity and Altered Glucose Homeostasis in a Gender-Specific Fashion in Adult Offspring

Alexandre Fisette, Helmholtz Zentrum München, Germany
Short Talk: Functional Identity of Hypothalamic Melanocortin Neurons Depends on Tbx3


Following Session is for Obesity and Adipose Tissue Biology (J7)

17:00—19:00
How Can We Translate Novel Discoveries into Obesity Treatment?
Meeting has ended...abstracts no longer viewable online.

Van Horne A/B
* Ruth E. Gimeno, Eli Lilly and Company, USA

* C. Ronald Kahn, Joslin Diabetes Center and Harvard Medical School, USA

Kevin L. Grove, Novo Nordisk, USA
Anti-Obesity Drug Development: The Potential and the Challenges

Barbara B. Kahn, Beth Israel Deaconess Medical Center, Harvard Medical School, USA
Adipose Tissue-Derived Lipokines

Max Nieuwdorp, University of Amsterdam, Netherlands
The Gut Microbiome – Tool or Target for Obesity Treatment?

Gerson S. Profeta, University of Campinas, Brazil
Short Talk: Fluoroquinolone-Related Molecules: Promising Drugs to Increase Browning of White Fat and miRNA Biogenesis

Xiaoyong Yang, Yale University School of Medicine, USA
Short Talk: Adipocyte OGT Governs Diet-Induced Hyperphagia and Obesity

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Mezzanine 2
19:30—22:00
Poster Session 3

Mezzanine 2

THURSDAY, FEBRUARY 14

07:00—08:00
Breakfast

Mezzanine 2
08:00—11:00
Disease Cachexia (Joint)
Meeting has ended...abstracts no longer viewable online.

Van Horne A/B
* Clifford J. Rosen, Maine Medical Center, USA

Stefan D. Anker, Charié Universitätsmedizin Berlin, Germany
Cardiac Cachexia

Bruce M. Spiegelman, Harvard Medical School, USA
Regulation of Mitochondria and Oxidative Metabolism: Futile Creatine Cycle (FCC)

Coffee Break

Daniel L. Marks, Oregon Health & Science University, USA
Neural Circuitry Mediating Cachexia

Roger D. Cone, University of Michigan, USA
The Melanocortin-3 Receptor as a Drug Target for Cachexia and Anorexia

11:00—17:00
On Own for Lunch

14:30—16:30
Workshop 2: Late Breaking Topics from Abstracts

Van Horne C
* Michael Krashes, NIDDK, National Institutes of Health, USA

Wei Xie, Harrington Discovery Institute, USA
Identification of an Asprosin Receptor

Anda Cornea, Novo Nordisk Research Center, USA
Distribution of Fluorescently Labeled Leptin in the Brain of Lean and DIO Mice

Isin Cakir, University of Michigan, USA
Inhibition of Histone Deacetylase 6 (HDAC6) Reverses Diet-Induced Obesity

Olivia D. Osborn, University of California, San Diego, USA
A Novel Approach to Block Antipsychotic-Induced Food Intake and Weight Gain

Maria Caterina De Rosa, Columbia University, USA
Generation of Paraventricular Hypothalamic Neurons from Human Pluripotent Stem Cells

Tim Gruber, Helmholtz Center Munich, Germany
Remodeling of the Hypothalamic Vasculature upon Hypercaloric Feeding Depends on Astroglial HIF1α and VEGF

Sinisa Hrvatin, Harvard Medical School, USA
PESCA: A Scalable Platform for the Development of Cell-Type-Specific Viral Drivers

Chrissa Dwyer, Ionis Pharmaceuticals, USA
Distribution and Activity of Antisense Oligonucleotides in the CNS of Rodents and Primates following Central Administration


Following Session is for Obesity and Adipose Tissue Biology (J7)

15:00—16:30
Clinical Obesity Management – Round Table Discussion

Van Horne A/B
* Timo D. Müller, Institute for Diabetes and Obesity, Germany

Matthias Blüher, University of Leipzig, Germany

Samuel Klein, Washington University School of Medicine, USA

16:30—17:00
Coffee Available

Van Horne Foyer
17:00—18:45
Drug Discovery for Eating Disorders
Meeting has ended...abstracts no longer viewable online.

Van Horne C
* Ruth E. Gimeno, Eli Lilly and Company, USA

Peter Kuehnen, Charité – Universitätsmedizin Berlin, Germany
Treatment of Monogenic Eating Disorders

Shamina M. Rangwala, Janssen, Johnson & Johnson, USA
Novel Therapeutics for Eating Disorders – Targeting the GDF15/GFRAL Axis and Beyond

xinle wu, , USA
The Metabolic Effects of GDF15 Are Mediated by the Orphan Receptor GFRAL

Robert Haws, Marshfield Medical Research Foundation, USA
Short Talk: Clinical Study Experience of the MC4R Agonist Setmelanotide in the Treatment of Rare Genetic Disorders of Obesity: Results from Bardet Biedl Syndrome and Alström Syndrome Cohorts in a Phase 2 Open Label Study


Following Session is for Obesity and Adipose Tissue Biology (J7)

17:00—18:45
Adipose Tissue Microenvironment
Meeting has ended...abstracts no longer viewable online.

Van Horne A/B
* Kevin L. Grove, Novo Nordisk, USA

Christoph Buettner, Mount Sinai School of Medicine, USA
Adipose Tissue Adaptive Thermogenesis

Catherine C. Muller-Staumont, IPBS CNRS UMR 5089, France
Adipose Tissue and Cancer: A Dangerous Dynamic Duo

Steven E. Shoelson, Harvard Medical School, Joslin Diabetes Center, USA
Adipose Tissue Microenvironment as Target of New Emerging Therapies

Silvia Corvera, University of Massachusetts Medical School, USA
Short Talk: Mechanisms of Development of Human Adipocyte Heterogeneity

18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Meeting has ended...abstracts no longer viewable online.

Van Horne C

Following Session is for Obesity and Adipose Tissue Biology (J7)

18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Meeting has ended...abstracts no longer viewable online.

Van Horne A/B
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Mezzanine 2
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Mezzanine 2

FRIDAY, FEBRUARY 15

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



Keystone Symposia thanks our Sponsor for generously supporting this meeting:

Novo Nordisk A/S

We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1 R13 DK118918-01

Funding for this conference was made possible (in part) by 1 R13 DK118918-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.


We gratefully acknowledge additional support for this conference from:

Research Diets, Inc.

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Janssen R&D: Pharmaceutical Companies of Johnson & Johnson


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Corporate Relations, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Nick Dua, Senior Director, Communications, Email: nickd@keystonesymposia.org,
Phone:+1 970-262-1179