Snowbird Resort Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

Targeted Protein Degradation (X8)

joint with the meeting on Ubiquitin Biology (X7)

Scientific Organizers: Rajesh Chopra, Nathanael Gray, Anita Gandhi and Georg Winter


March 29—April 1, 2020

Snowbird Resort, Snowbird, Utah, USA


Sponsored by Incyte Corporation


BEWARE of booking lodging through companies unaffiliated with Keystone Symposia. Click here for more details.

Keystone Symposia is committed to maintaining a positive and respectful environment at its meetings. To this end, please review and comply with our policies.

Registered attendees of one meeting in a joint pair may participate in sessions of the other, pending space availability.

DEADLINES:
*All deadlines end at 11:59 PM US Mountain Standard Time
Scholarship Deadline: Nov 21, 2019 [details]
Discounted Abstract Deadline: Nov 21, 2019 [details]
Abstract Deadline: Dec 19, 2019 [details]
Discounted Registration Deadline: Jan 29, 2020 [details]

Click here to view Cancellation Policy

Submit an Abstract Register Yourself Deadlines and Fees

Rates and Deadlines listed below are for the 2020-X8 "Targeted Protein Degradation" conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details
Before and On November 21, 2019 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details
After November 21, 2019 until December 19, 2019 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
Scholarship
More details
November 21, 2019 n/a
Discounted NON-STUDENT Registration
More details
Before and On January 29, 2020 795.00 USD
(includes 200.00 discount)
Regular NON-STUDENT Registration
More details
After January 29, 2020 995.00 USD
Discounted STUDENT Registration
More details
Before and On January 29, 2020 570.00 USD
(includes 200.00 discount)
Regular STUDENT Registration
More details
After January 29, 2020 770.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will accept no liability for money loss through bank charges, transfers or currency fluctuations.

Apply for a Scholarship



Discounted Abstract Deadline: November 21, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time

Abstract Submission Fee: 100.00 USD*
Submission by this date receives 50.00 USD discount.
*50.00 USD will be applied to Registration Fee when you register

Abstract Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadlines. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract early allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • accept your abstract online
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
(The Abstract Deadline: is December 19, 2019)

Global Health Travel Award Deadline:

*All deadlines end at 11:59 PM US Mountain Standard Time


Global Health Travel Award Details: You MUST complete your Global Health Travel Award appplication by the Global Health Travel Award Deadline and complete the other required steps (verify your contact information and submit a recommendation letter) to be considered for a travel award.


Click here to learn more about Global Health Travel Awards.

Scholarship Deadline: November 21, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time


Scholarship Details: You MUST submit your abstract by the Scholarship Deadline and complete the other required steps (submit a scholarship application and submit a mentor letter) to be considered for a scholarship.

Click here to learn more about Scholarships.

Abstract Deadline: December 19, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time


Abstract Submission Fee: 100.00 USD*
*50.00 USD will be applied to Registration Fee when you register

Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadline. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract by the Abstract Deadline allows us to:

  • submit your abstract to organizers to be considered for a short talk
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
Abstracts submitted after the Abstract Deadline will NOT be considered for a short talk.

(Discounted Abstract Deadline: is November 21, 2019)

Discounted Registration Deadline: January 29, 2020

*All deadlines end at 11:59 PM US Mountain Standard Time


Registration Fee: 795.00 USD* (includes 200.00 USD discount)
Student Registration Fee: 570.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

After the Discounted Registration Deadline:


Registration Fee: 995.00 USD*
Student Registration Fee: 770.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

Registration spaces are limited and may fill prior to discounted registration deadline.

Please be advised that some meeting participants have received calls and emails from a number of different housing services, including "Exhibitors Housing Services," “Expo Housing Services,” "Global Housing," etc. THESE COMPANIES ARE NOT AFFILIATED WITH KEYSTONE SYMPOSIA and are not authorized by Keystone Symposia to contact you. These companies may tell you that the meeting is filling, without any actual knowledge to that effect, and pressure you into giving them your credit card number to make a lodging reservation with them.

We highly recommend that you not make a reservation with these companies or any other housing service! These companies' representations to participants have been misleading. Please report any calls or correspondence you might have received to Keystone Symposia and book only through lodging links in your Keystone Symposia account, an established travel agency or directly with the hotel(s) listed on our website.
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Sunday, March 29 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Wednesday, April 1 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Thursday, April 2 in order to fully experience the meeting.

SUNDAY, MARCH 29

16:00—20:00
Arrival and Registration

Ballroom Lobby
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Ballroom Lobby

MONDAY, MARCH 30

07:00—08:00
Breakfast

Golden Cliff/Eagles
08:00—09:00
Welcome and Keynote Address
Registered attendees can view abstracts starting on 02/29/2020

Ballroom 3
James E. Bradner, Novartis Institutes for BioMedical Research, USA
Targeted Protein Degradation: Chemical Biology and Therapeutics


Following Session is for Ubiquitin Biology (X7)

08:00—09:00
Welcome and Keynote Address
Registered attendees can view abstracts starting on 02/29/2020

Ballroom 1-2
Ivan Dikic, Goethe University Medical School, Germany
Phosphoribosyl-Dependent Ubiquitination and Pathogenesis

09:00—11:15
Proteolysis Targeting Chimeras (PROTACs)
Registered attendees can view abstracts starting on 02/29/2020

Ballroom 3
Craig M. Crews, Yale University, USA
PROTACs : Inducing Protein Degradation as a Therapeutic Strategy

Coffee Break

Alessio Ciulli, University of Dundee, School of Life Sciences, UK
Structural Biology and Insights into PROTAC Mechanism of Action

Nathanael Gray, Dana-Farber Cancer Center, USA
Targeting Kinases Via Protein Degradation

Short Talks Chosen from Abstracts


Following Session is for Ubiquitin Biology (X7)

09:00—11:15
Regulating Nuclear Function with Ubiquitin
Registered attendees can view abstracts starting on 02/29/2020

Ballroom 1-2
Niels Mailand, University of Copenhagen, Denmark
Ubiquitin-Dependent Signaling in the DNA Damage Response

Coffee Break

Jo R. Morris, University of Birmingham, UK
SUMOylation in the DNA Double-Strand Break Response

Karim Labib, University of Dundee, UK
Destroying the Eukaryotic Replisome

Short Talks Chosen from Abstracts

11:15—17:00
On Own for Lunch

11:15—13:00
Poster Setup

Superior/Superior Lobby/Wasatch
13:00—22:00
Poster Viewing

Superior/Superior Lobby/Wasatch
14:30—16:30
Workshop 1

Ballroom 3
Short Talks Chosen from Abstracts

16:30—17:00
Coffee Available

Ballroom Lobby
17:00—19:00
Mechanisms of Protein Ubiquitylation and Degradation (Joint)
Registered attendees can view abstracts starting on 02/29/2020

Ballroom 1-3
Brenda A. Schulman, Max Planck Institute of Biochemistry, Germany
Cullin-RING E3 Ligation Mechanisms

Nicolas H. Thomä, Friedrich Miescher Institute for Biomedical Research, Switzerland
CRL4-CRBN Ubiquitin Ligase-Dependent Targeting of Zinc-Finger Degrons

Kylie J. Walters, NCI, National Institutes of Health, USA
Probing Proteasome Architecture to Impact Protein Degradation

Short Talks Chosen from Abstracts

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Superior/Superior Lobby/Wasatch
19:30—22:00
Poster Session 1

Superior/Superior Lobby/Wasatch

TUESDAY, MARCH 31

07:00—08:00
Breakfast

Golden Cliff/Eagles
08:00—11:00
Strategies for Therapeutic Targeting of the Ubiquitin Proteasome System (Joint)
Registered attendees can view abstracts starting on 02/29/2020

Ballroom 1-3
David Komander, Walter and Eliza Hall Institute of Medical Research, Australia
Novel Tools and Methods to Study Ubiquitin Modifications

Ingrid E. Wertz, Genentech, Inc., USA
Development of Small Molecule Inhibitors for Deubiquitylating Enzymes

Coffee Break

Neil Bence, Nurix Inc., USA
Therapeutic Targeting and Utilization of Ubiquitin Ligases in Drug Discovery

Sara Buhrlage, Dana-Farber Cancer Institute, USA
Approaches to Identify New DUB Inhibitors

Short Talks Chosen from Abstracts

11:00—17:00
On Own for Lunch

11:00—13:00
Poster Setup

Superior/Superior Lobby/Wasatch
13:00—22:00
Poster Viewing

Superior/Superior Lobby/Wasatch
16:30—17:00
Coffee Available

Ballroom Lobby
17:00—19:00
DCAFs as Targets for Protein Degradation
Registered attendees can view abstracts starting on 02/29/2020

Ballroom 3
Anita K. Gandhi, Celgene, USA
Emerging CELMoDs and Clinical Update

Deepak Nijhawan, University of Texas Southwestern Medical Center, USA
DCAF15 and Other DCAFs as Modulators for Protein Degradation

Georg E. Winter, CeMM Research Center for Molecular Medicine, Austria
Genetic Determinants of Targeted Protein Degradation

Short Talks Chosen from Abstracts


Following Session is for Ubiquitin Biology (X7)

17:00—19:00
Ubiquitin-Dependent Quality Control Mechanisms
Registered attendees can view abstracts starting on 02/29/2020

Ballroom 1-2
Thibault Mayor, University of British Columbia, Canada
Ubiquitin Ligases in Cytosolic Protein Quality Control

Michael Rape, University of California, Berkeley, USA
The Role of Heterotypic Ubiquitin Chains in Protein Quality Control

Eric J. Bennett, University of California, San Diego, USA
Ribosome Associated Quality Control Mechanisms

Short Talks Chosen from Abstracts

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Superior/Superior Lobby/Wasatch
19:30—22:00
Poster Session 2

Superior/Superior Lobby/Wasatch

WEDNESDAY, APRIL 1

07:00—08:00
Breakfast

Golden Cliff/Eagles
08:00—11:00
Novel Approaches to Protein Degradation/Homeostasis for Therapeutics
Registered attendees can view abstracts starting on 02/29/2020

Ballroom 3
Leo James, MRC Laboratory of Molecular Biology, UK
Antibody Coated Virions and the E3 Ubiquitin Ligase TRIM 21 for Modulating Intracellular Tumoral Immunity

Titia K. Sixma, Netherlands Cancer Institute, Netherlands
Ubiquitin Conjugation and DUBs in DNA Repair

Coffee Break

Ryan Potts, St. Jude Children's Research Hospital, USA
MAGE Ubiquitin Ligases

Shaomeng Wang, University of Michigan, USA
Talk Title to be Announced

Short Talks Chosen from Abstracts


Following Session is for Ubiquitin Biology (X7)

08:00—11:00
New Paradigms in Protein Ubiquitylation
Registered attendees can view abstracts starting on 02/29/2020

Ballroom 1-2
Feng Shao, National Institute of Biological Sciences, China
Novel Mechanisms Used by Pathogens to Suppress Ubiquitin Signaling

Emily Troemel, University of California, San Diego, USA
Ubiquitin Signaling within the Intracellular Pathogen Response Pathway

Coffee Break

Heran Darwin, New York University School of Medicine, USA
Proteasomal Regulation of Mycobacterial Virulence

Katerina Artavanis-Tsakonas, University of Cambridge, UK
Control of Ubiquitination in Plasmodium parasites

Short Talks Chosen from Abstracts

11:00—17:00
On Own for Lunch

14:30—16:30
Workshop 2

Short Talks Chosen from Abstracts


Following Session is for Ubiquitin Biology (X7)

14:30—16:30
Workshop

Ballroom 2
Short Talks Chosen from Abstracts

16:30—17:00
Coffee Available

Ballroom Lobby
17:00—18:45
Methodologies and Technologies for the Investigation of Protein Degradation
Registered attendees can view abstracts starting on 02/29/2020

Ballroom 3
Rajesh Chopra, Cancer Research UK Cancer, UK
Phenotypic Screens for Identifying Modulators of E3 Ligase Function

Takumi Ito, Tokyo Medical University, Japan
Analysis of Neosubstrates of CRL4CRBN in the Presence of Thalidomide and Derivatives.

Hsueh-Chi S. Yen, Academia Sinica, Taiwan
C-Terminal End-Directed Protein Elimination by CRL2 Ubiquitin Ligases

Short Talk Chosen from Abstracts


Following Session is for Ubiquitin Biology (X7)

17:00—18:45
Ubiquitin System Dysregulation in Disease
Registered attendees can view abstracts starting on 02/29/2020

Ballroom 2
Richard J. Youle, NINDS, National Institutes of Health, USA
Familial Parkinson’s Disease and ALS Linked to Mitochondrial Fidelity and Selective Autophagy

J. Wade Harper, Harvard Medical School, USA
Systematic Analysis of Ubiquitin System Dysfunction in Mitochondrial Disorders

James A. Olzmann, University of California, Berkeley, USA
Ubiquitin-Dependent Regulation of Lipid Droplet Proteome Dynamics

Short Talk Chosen from Abstracts

18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 02/29/2020

Ballroom 3

Following Session is for Ubiquitin Biology (X7)

18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 02/29/2020

Ballroom 2
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Ballroom 1-2
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Ballroom 1-2

THURSDAY, APRIL 2

 
Departure


*Session Chair †Invited, not yet responded.



Keystone Symposia thanks our Sponsor for generously supporting this meeting:

Incyte Corporation

We gratefully acknowledge additional support for this conference from:

Tocris Bioscience, a Bio-Techne Brand

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Corporate Relations, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Nick Dua, Senior Director, Communications, Email: nickd@keystonesymposia.org,
Phone:+1 970-262-1179