Sagebrush Inn & Suites Floorplan

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This meeting took place in 2001



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The Molecular Medicine of Colorectal Cancer (F2)


Organizer(s) Vincent W. Yang and Raymond N. DuBois
January 30—February 4, 2001
Sagebrush Inn & Suites • Taos, New Mexico USA
Abstract Deadline: Sep 29, 2000
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Nov 30, 2000

Summary of Meeting:
Significant progress has been made in understanding the molecular mechanisms of colorectal cancer (CRC) in the last decade. Key genes, the mutations that lead to increased susceptibility to CRC have been identified and characterized. The identification of these genes has enabled large-scale genetic screening in the population for affected individuals. Various pharmacological agents have also been shown to be promising in the prevention or treatment of CRC. These major advances are likely to affect the conventional clinical approaches to CRC, leading to improved diagnostic and therapeutic methodologies for this serious disease. The objective of this colloquium is to assemble a group of expert investigators from both scientific and clinical communities in order to formulate novel approaches to the diagnosis and management of CRC. It is hoped that at the conclusion of the colloquium that each group of investigators will develop new ideas by interacting with the other and subsequently apply these new ideas to their fields of study.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


TUESDAY, JANUARY 30

14:00—19:00
Registration

Chamisa Lobby
18:15—19:15
Welcome

Chamisa Lobby
19:15—19:30
Orientation

Chamisa Ballroom 2
19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 2
Sanford D. Markowitz, Case Western Reserve University, USA
Pathways of Gastrointestinal Neoplasia


WEDNESDAY, JANUARY 31

07:00—08:00
Breakfast

Los Vaqueros
08:00—11:00
Advances in Colorectal Cancer Screening. Session Sponsored by Merck & Co., Inc.
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 2
* Bernard Levin, University of Texas, USA

Sidney J. Winawer, Memorial Sloan-Kettering Cancer Center, USA
Colorectal Cancer Screening

Bernard Levin, University of Texas, USA
Implementation of Colorectal Cancer Screening: The Challenge

David A. Ahlquist, Mayo Clinic, USA
Molecular Markers in Stool: New Targets for Colorectal Cancer Screening

Robert S. Bresalier, Henry Ford Health Sciences Center, USA
Mucins and Mucin Binding Proteins in Colon Cancer Metastasis

09:20—09:40
Coffee Break

Chamisa Lobby
11:00—13:00
Poster Setup

Chamisa Ballroom 1
16:30—18:30
POSTER SESSION 1: Advances in Colorectal Cancer Screening/Novel Mechanisms

Chamisa Ballroom 1
17:30—18:30
Social Hour

Chamisa Ballroom 1
19:50—20:10
Coffee Break

Chamisa Lobby
18:30—21:30
Novel Mechanisms. Session Sponsored by Merck & Co., Inc.
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 2
* Anil K. Rustgi, University of Pennsylvania, USA
Approaches to New Tumor Suppressor Genes in Colon Cancer

C. Richard Boland, University of California, San Diego, USA
Regulation of the DNA Mismatch Repair Genes in the Genesis of Colorectal Cancer

Fillippo Randazzo, Bill & Melinda Gates Foundation, USA
Colon Cancer Pathway Analysis, DNA MicroArrays, and the Identification of Therapeutic Targets

John M. Carethers, VA San Diego Healthcare, USA
Genetic Pathways Included in Hamartomatous Polyposis Syndromes

Marian Waterman, University of California, Irvine, USA
Expression of LEF/TCF Proteins in Colon Cancer


THURSDAY, FEBRUARY 1

07:00—08:00
Breakfast

Los Vaqueros
08:00—11:00
Tumor Markers
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 2
* Scott A. Waldman, Thomas Jefferson University, USA
Guanylyl Cyclase C and Gastrointestinal Neoplasia

David Weinberg, Thomas Jefferson University, USA
New Targets for Colorectal Cancer Genetic Testing

David S.B. Hoon, John Wayne Cancer Institute, USA
Molecular Ultrastaging of Early Stage Colon Cancer Patients: Micrometastasis Identification in the Sentinel Lymph Node

Richard A. Fishel, Ohio State University, USA
Mismatch Repair: The Mechanics of an Adenosine Nucleotide-Regulated Molecular Switch

09:20—09:40
Coffee Break

Chamisa Lobby
11:00—13:00
Poster Setup

Chamisa Ballroom 1
16:30—18:30
POSTER SESSION 2: Tumor Markers/Tumor Vaccines and Other Novel Therapies

Chamisa Ballroom 1
17:30—18:30
Social Hour

Chamisa Ballroom 1
19:50—20:10
Coffee Break

Chamisa Lobby
18:30—21:30
Tumor Vaccines and Other Novel Therapies. Session Sponsored by Pharmacia Corporation.
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 2
* Daniel G. Haller, University of Pennsylvania, USA

Kenneth A. Foon, Abgenix, Inc., USA
Anti-Idiotype Monoclonal Antibody that Mimics Carcinomembryonic Antigen

Elizabeth M. Jaffee, Johns Hopkins University, USA
Engineering Immune Responses to Eradicate Cancer: From Mice to Men

Michael A. Choti, Johns Hopkins University, USA
Cancer Vaccines for Colorectal Cancer

Louis M. Weiner, Georgetown University Medical Center, USA
Novel Approaches to the Immunotherapy of Colorectal Cancer and Other Solid Tumors

Daniel G. Haller, University of Pennsylvania, USA
Advances in Chemotherapy for Colorectal Cancer


FRIDAY, FEBRUARY 2

07:00—08:00
Breakfast

Los Vaqueros
08:00—11:30
Chemoprevention. Session Sponsored by Merck & Co., Inc.
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 2
* Raymond N. DuBois, Arizona State University, USA
Chemoprevention of Colorectal Cancer and Selective COX-2 Inhibitors

Chinthalapally V. Rao, American Health Foundation, USA
Molecular Targets for the Chemoprevention of Colorectal Cancer

Gary J. Kelloff, National Cancer Institute, National Institutes of Health, USA
Progress in Colon Cancer Chemoprevention

Russell F. Jacoby, University of Wisconsin, USA
Effects of the Nonspecific COX1/2 Inhibitor Piroxicam and the Ornithine Decarboxylase Inhibitor Difluoromethylornithine (DFMO) on Development of Intestinal Tumors in Mice Bearing Germline Alterations in the MSH2 or APC Genes

Karen Seibert, Pfizer Research Laboratories, USA
COX-2 Inhibition in Models of Colon Cancer Prevention and Tumorigenesis

09:20—09:40
Coffee Break

Chamisa Lobby
11:00—13:00
Poster Setup

Chamisa Ballroom 1
16:30—18:30
POSTER SESSION 3: Chemoprevention/Genomic Profiling/Gene Testing

Chamisa Ballroom 1
17:30—18:30
Social Hour

Chamisa Ballroom 1
19:50—20:10
Coffee Break

Chamisa Lobby
18:30—21:30
Genomic Profiling
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 2
* Vincent W. Yang, Emory University, USA

Linda A. Lee, Johns Hopkins School of Medicine, USA
A Novel c-Myc Function in vivo Revealed by Microarray Analysis

Vincent W. Yang, Emory University, USA
Transcriptional Program as Defined by Gene Profiling

Charles M. Perou, University of North Carolina at Chapel Hill, USA
Molecular Portraits of Human Breast Tumors

Phillip J. Buckhaults, Johns Hopkins School of Medicine, USA
Transcriptional Alterations During Colorectal Cancer Progression

Daniel A. Notterman, Princeton University, USA
Transcriptional Gene Expression Profiling of Colorectal Cancer and Adenoma: Discriminating Histological Class and p53 Status on the Basis of Transcriptional Pattern


SATURDAY, FEBRUARY 3

07:00—08:00
Breakfast

Los Vaqueros
08:00—11:00
Gene Testing
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 2
* Francis M. Giardiello, Johns Hopkins University, USA
Genetic Testing in Hereditary Colorectal Cancer

Gloria M. Petersen, Mayo Clinic, USA
Genetic Risk Assessment for Colorectal Cancer

Randall Burt, University of Utah School of Medicine, USA
Translational Genetic Testing for Inherited Colon Cancer

Albert de la Chapelle, Ohio State University, USA
Genetic Predisposition to Colorectal Cancer

Steven H. Itzkowitz, Mount Sinai Medical Center, USA

09:20—09:40
Coffee Break

Chamisa Lobby
17:00—18:00
Workshop: New Genomic Technologies and Modern Medicine

Chamisa Ballroom 2
Michael E. Hogan, University of Arizonia, USA
Advanced Archive Technolog, DNA Microarrays and Bioinformatics forVery Large Scale Biomarker Discovery

Fillippo Randazzo, Bill & Melinda Gates Foundation, USA

17:00—18:00
Coffee Available

Chamisa Lobby
19:00—20:00
Social Hour

Chamisa Lobby
20:00—22:00
Banquet

Chamisa Ballroom 1
21:00—00:00
Entertainment

Chamisa Ballroom 1

SUNDAY, FEBRUARY 4

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1 R13 CA91378-01




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