Snowbird Resort Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

This meeting took place in 2002



For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

JAKs and STATs: Activation and Biologic Impact (A2)


Organizer(s) George R. Stark, Ian M. Kerr and James E. Darnell, Jr.
January 13—18, 2002
Snowbird Resort • Snowbird, Utah USA
Abstract Deadline: Oct 1, 2001
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Nov 13, 2001

Sponsored in part by The Director's Sponsor Fund

Summary of Meeting:
The JAK tyrosine kinases and STAT transcription factors are now appreciated to be essential for the function of many pathways that regulate gene expression and biological function. Exciting current research has revealed, for example, family members in slime molds and insects, both positive and negative regulation of gene expression, cross-responses to pathways that use serine phosphorylation, and that Stat3 is an oncogene and Stat1 a tumor suppressor. Future issues: determine more protein structures, mechanisms and significance of serine phosphorylation, details of pivotal protein-protein interactions, basis of ligand-specific signals. Meeting goals: to cross-fertilize a very large range of research projects in an exciting and rapidly evolving field.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SUNDAY, JANUARY 13

16:00—19:00
Registration

Ballroom Lobby
18:15—19:15
Welcome

Ballroom Lobby
19:15—19:30
Orientation

Ballroom 3
19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Ballroom 3
C. David Allis, Rockefeller University, USA
The Histone Modification Circus: Balancing Acts Fundamental to Human Biology and Disease


MONDAY, JANUARY 14

07:00—08:00
Breakfast

Golden Cliff
08:00—12:00
Receptor/JAK Complexes, Receptor Cross-Talk, Modular Signaling/STATs
Meeting has ended...abstracts no longer viewable online.

Ballroom 3
* Ian M. Kerr, Cancer Research UK, UK
JAK/STAT Signaling

Pipsa I. Saharinen, Haartman Institute, University of Helsinki, Finland
Short Talk: The Pseudokinase Domain in the Regulation of JAK2 and JAK3 Tyrosine Kinases

K. Christopher Garcia, Stanford University School of Medicine, USA
Short Talk: The Interaction between gp130 and Viral Interleukin-6: A Paradigm for the Architecture of gp130-Cytokine Signaling Assemblies

Nicholas K. Tonks, Cold Spring Harbor Laboratory, USA

Tadatsugu Taniguchi, University of Tokyo, Japan
STATs and IRFs in the Regulation of Immunity and Bone Remodeling

Stephen Brown, University of Cambridge, UK
Short Talk: Characterisation of Domeless, the Drosophila JAK/STAT Receptor

09:20—09:40
Coffee Break

Ballroom Lobby
12:00—13:00
Poster Setup

Ballroom 2
13:00—21:30
Poster Viewing

Ballroom 2
14:00—16:00
Workshop 1

Ballroom 3
Athanasia D. Panopoulos, University of Texas MD Anderson Cancer Center, USA
Cytokine-Inducible Expression of the Myeloid-Specific Integrin alphaMbeta2 (CD11b/CD18) is Regulated by STAT3-Dependent Activation of PU.1

* Nancy C. Reich, Stony Brook University, USA
Regulated Cellular Localization of STATs and Influence of Small GTPases

Pravin B. Sehgal, New York Medical College, USA
STATs in Membrane Rafts

Erika A. Bach, New York University School of Medicine, USA
A Genetic Screen to Identify New Components of the Drosophila JAK-STAT Pathway

Antonis E. Koromilas, Lady Davis Institute, McGill University, Canada
The Interferon-Inducible Protein Kinase PKR is a Mediator of JAK-STAT Activation and Translational Control

Joe F. Lau, Mount Sinai School of Medicine, USA
A Hybrid IRF9-STAT2 Transcription Factor Recapitulates Gene Expression and Biological Responses

16:00—16:30
Coffee & Snacks Available

Ballroom Lobby
16:30—18:30
Transcription Mechanisms 1
Meeting has ended...abstracts no longer viewable online.

Ballroom 3
* James E. Darnell, Rockefeller University, USA
Transcriptional Activation by STATs and Biologic Impact

Joo Yeon Yoo, POSTECH, South Korea
Short Talk: Specific Ablation of STAT3beta Distorts the Pattern of STAT3-Responsive Gene Expression and Impairs Recovery from Endotoxic Shock

J. Jillian Zhang, Cornell Medical School, USA
Short Talk: Analysis of Trancription Co-Activators of STAT1 in IFN-gamma Signaling

Jan H. Tavernier, Ghent University, Belgium
Short Talk: Design and Application of a Cytokine Receptor-Based Interaction Trap

Carmen Herrero, Hospital for Special Surgery, USA
Short Talk: Modulation of IL-10 Activity and Signaling during Macrophage Activation

18:30—19:30
Welcome Mixer

Ballroom Lobby
19:30—21:30
Poster Session 1

Ballroom 2

TUESDAY, JANUARY 15

07:00—08:00
Breakfast

Golden Cliff
08:00—12:00
Negative Regulation
Meeting has ended...abstracts no longer viewable online.

Ballroom 3
* Douglas J. Hilton, Walter and Eliza Hall Institute of Medical Research, Australia
SOCS Proteins - Negative Regulations of Cytokine Signal Transduction

Ann L. Cornish, University of Melbourne, Australia
Short Talk: SOCS-1 is Important in the Negative Regulation of T Cell Activation

Alexander H. Dalpke, University Heidelberg, Germany
Short Talk: Toll-Like Receptor-Dependent Microbial Stimuli Modulate Cytokine Responses in Antigen Presenting Cells by Inducing Suppressors of Cytokine Signaling

Thomas A.F. Decker, Vienna Biocenter, University of Vienna, Austria
Short Talk: The STAT1 Binding Motif of the IFN-gamma Receptor is Sufficient to Mediate STAT5 Activation and Its Repression by SOCS3

Christin Carter-Su, University of Michigan Medical School, USA
Regulation of JAK Activity and Cytokine Signaling by Members of the SH2-B Family of Adapter Proteins

Ke Shuai, University of California, Los Angeles, USA
Inactivation of STAT Signaling in the Nucleus

Yi Eve Sun, University of California, Los Angeles, USA
Short Talk: Neurogenin1 Inhibits the JAK-STAT Pathway Via Multiple Routes

09:20—09:40
Coffee Break

Ballroom Lobby
12:00—13:00
Poster Setup

Ballroom 2
13:00—21:30
Poster Viewing

Ballroom 2
16:00—16:30
Coffee & Snacks Available

Ballroom Lobby
16:30—18:30
Transcription Mechanisms 2
Meeting has ended...abstracts no longer viewable online.

Ballroom 3
* Christin Carter-Su, University of Michigan Medical School, USA

Peter C. Heinrich, Universitätsklinikum Aachen, Germany
Modulation of IL-6-Type Cytokine Signaling

Heather A. Bruns, Indiana University School of Medicine, USA
Short Talk: A Constitutively Active STAT6 is not Sufficient to Alter B Cell Gene Expression and Function in the Absence of IL-4

Edith B. Pfitzner, Institute for Biomedical Research, Germany
Short Talk: Transciptional Activation by STAT6 Requires the Direct Interaction with NCoA-1

Curt M. Horvath, Northwestern University, USA
Analysis of STAT Transcription Mechanisms

18:30—19:30
Welcome Mixer

Ballroom Lobby
19:30—21:30
Poster Session 2

Ballroom 2

WEDNESDAY, JANUARY 16

07:00—08:00
Breakfast

Golden Cliff
08:00—12:00
Oncogenesis, Immune Regulation, Tissue-Specific Effects 1
Meeting has ended...abstracts no longer viewable online.

Ballroom 3
John J. O'Shea, NIAMS, National Institutes of Health, USA
Cytokine Signaling and Lymphoid Development, Differentiation and Immunoregulation

Kenneth M. Murphy, HHMI/Washington University School of Medicine, USA
Mechanisms of STAT4 in Th1 Development

* Robert D. Schreiber, Washington University School of Medicine, USA
STAT1 and Lymphocytes: Tumor Suppression and Tumor Editing

David E. Levy, New York University School of Medicine, USA
STAT Transcriptional Mechanisms in Host Defense and Cancer

George R. Stark, Case Western Reserve University, USA
Stat1-Independent Responses to IFNgamma and Stat 1,3-Dependent Transcription Without Tyrosine Phosphorylation

09:20—09:40
Coffee Break

Ballroom Lobby
13:00—21:30
Poster Viewing

Ballroom 2
14:00—16:00
Workshop 2

Ballroom 3
* Peter C. Heinrich, Universitätsklinikum Aachen, Germany

Markus H. Heim, University Hospital Basel, Switzerland
Inhibition of Interferon Alpha Signaling Through the JAK-STAT Pathway in HVC Transgenic Mice

Simone Radtke, Medical School RWTH Aachen, Germany
Short Talk: Novel Role of Janus Kinase 1 in the Regulation of Oncostatin M Receptor Surface Expression

Lily Huang, University of Texas Southwestern Medical Center at Dallas, USA
Short Talk: The N-Terminal Domain of Janus Kinase 2 is Required for Golgi Processing and Cell Surface Expression of Erythropoietin Receptor

Jennifer Rubin Grandis, University of Pittsburgh Eye & Ear Institute, USA
STATs in Head and Neck Cancer

June H. Lee, University of California, San Francisco, USA
IL-13 and IL-4 Induce Differential Gene Expression in Bronchial Smooth Muscle Cells and Lung Fibroblasts

Thomas Kay, St. Vincent's Institute of Medical Research, Australia
Hypersensitivity to TNF-alpha-Induced Cell Death in Pancreatic beta Cells with SOCS-1 Deficiency

Bao Q. Vuong, City College of New York, CUNY, USA
Pim Serine/Theronine Kinases Regulate the Stability of SOCS-1 Protein

16:00—16:30
Coffee & Snacks Available

Ballroom Lobby
16:30—18:30
Oncogenesis, Immune Regulation, Tissue-Specific Effects 2
Meeting has ended...abstracts no longer viewable online.

Ballroom 3
* George R. Stark, Case Western Reserve University, USA

Merav Socolovsky, University of Massachusetts Medical School, USA
The Roles of EpoR and STAT5 in Red Cell Formation

James N. Ihle, St. Jude Children's Research Hospital, USA
JAKs and STATs in Cytokine Signaling

M. A.Q. Siddiqui, Downstate Medical Center, State University of New York, USA
JAK/STAT Signaling Mediates Myocardial Dysfunction during Hypertrophy and Ischemia

18:30—19:30
Welcome Mixer

Ballroom Lobby
19:30—21:30
Poster Sessions 1 & 2

Ballroom 2

THURSDAY, JANUARY 17

07:00—08:00
Breakfast

Golden Cliff
08:00—12:00
Growth Regulation, Constitutive Gene Expression, Alternate Pathways, Apoptosis
Meeting has ended...abstracts no longer viewable online.

Ballroom 3
* David E. Levy, New York University School of Medicine, USA

Norbert Perrimon, Harvard Medical School, USA
Studies on the Drosophila JAK/STAT Pathway

Jacqueline F. Bromberg, Memorial Sloan Kettering Cancer Center, USA
Short Talk: The Role of STAT3 in Breast Cancer Tumorigenesis

Keith Syson Chan, Stem Cells and Regenerative Medicine, USA
Short Talk: Activation of STAT3 during Multistage Skin Tumorigenesis

Mariusz A. Wasik, University of Pennsylvania, USA
Short Talk: Multilevel Dysregulation of STAT3 Activation in T-Cell Lymphomas Expressing Anaplastic Lymphoma Kinase (ALK)

James L. Watson, McMaster University, Canada
Short Talk: (-)-Epigallocatechin Gallate (EGCG) Inhibits IFNgamma-Induced STAT1 Activation in Human T84 Epithelia: Implications for the Regulation of Intestinal Barrier Function

Leonidas C. Platanias, University of Illinois at Chicago, USA
Role of Map Kinases in Interferon Signaling

Anna I. Dimberg, Uppsala University Hospital, Sweden
Short Talk: Serine-727 Phosphorylated STAT1 is Required for ATRA-Induced G0/G1 Arrest of U-937 Cells and the Associated Regulation of Cyclins and p27Kip1

Tania C. Benatar, University of Toronto, Canada
Short Talk: ES Cell Fate is Determined Through a Complex Balance of Intracellular Signaling Pathways

09:20—09:40
Coffee Break

Ballroom Lobby
16:00—16:30
Coffee & Snacks Available

Ballroom Lobby
16:30—18:30
Slime Molds to Zebrafish
Meeting has ended...abstracts no longer viewable online.

Ballroom 3
* Jeffrey G. Williams, University of Dundee, School of Biological Sciences, UK
Regulation of the Nuclear Import and Export of Dictyostelium STAT Proteins: Pointers from Ancestral STATs?

Leanne Jones, University of California, Los Angeles, USA
Short Talk: Stem Cell Self-Renewal Specified by JAK-STAT Activation in Response to a Support Cell Cue

Toshio Hirano, Osaka University Graduate School of Medicine, Japan
Roles of JAK/STAT Signaling in Gastrulation

18:30—19:30
Welcome Mixer

Ballroom 2/Lobby
19:30—22:30
Entertainment

Ballroom 2

FRIDAY, JANUARY 18

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1 R13 CA30714-01




We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676