Hilton Santa Fe Historic Plaza Hotel Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

This meeting took place in 2002



For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Rethinking the Pathogenesis of Asthma (B4)


Organizer(s) Daniel Rotrosen, Jeffrey M. Drazen and Stephen T. Holgate
February 8—13, 2002
Hilton Santa Fe Historic Plaza Hotel • Santa Fe, New Mexico USA
Abstract Deadline: Oct 8, 2001
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Dec 7, 2001

Sponsored by Aventis Pharmaceuticals, Inc. and Inflazyme Pharmaceuticals, Ltd.

Summary of Meeting:
Asthma is a major cause of illness and disability worldwide. During the past 2-3 decades, the prevalence of asthma and morbidity due to asthma have increased substantially. Since previous models of asthma pathogenesis cannot explain this trend, this conference will bring together basic and clinical scientists representing a wide range of scientific disciplines to reexamine the pathogenesis of asthma from the perspective of new insights into human immune system development and biology and an expanding awareness of the role of environmental factors. Examples include advances in gene discovery and receptor-mediated signaling, an appreciation of the importance of early life events in molding the allergic diathesis, and an understanding of the role of the innate immune system in the establishment and maintenance of airway inflammation and hyperreactivity. This conference will highlight current research and future directions in areas that hold promise for the development of new therapeutic agents and preventive approaches.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


FRIDAY, FEBRUARY 8

16:00—19:00
Registration

Promenade
18:15—19:15
Welcome

Promenade
19:15—19:30
Orientation

Mesa A-B
19:30—20:30
Keynote Address. Sponsored in part by OSI Pharmaceuticals, Inc.
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
Andrew Saxon, University of California, Los Angeles, USA
Environment, the Immune System and Asthma


SATURDAY, FEBRUARY 9

07:00—08:00
Breakfast

Chamisa
08:00—11:00
Developmental Immunobiology and Immunologic Origins of Asthma
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Fernando D. Martinez, University of Arizona, USA

Denis J. Reen, Our Lady's Hospital for Sick Children, Ireland
T-Cell Function at Birth in Humans

Patrick G. Holt, University of Western Australia, Australia
Fetal and Neonatal Immunity in Asthma and Allergy

Becky Adkins, University of Miami Medical School, USA
Development of Murine Neonatal Th1/Th2 Function

Erika von Mutius, University Children's Hospital, Munich, Germany
The Hygiene Hypothesis

09:20—09:40
Coffee Break

Promenade
11:00—13:00
Poster Setup

Mesa C
13:00—22:00
Poster Viewing

Mesa C
14:30—16:30
Workshop 1

Mesa A-B
* K. Frank Austen, Harvard Medical School, USA

Talal A. Chatila, University of California, Los Angeles, USA
Function of the I4R Motif in IL-4Ra Signaling

Udo Herz, Philipps-Universität, Germany
Influence of Maternal Allergic Sensitization on the Development of Atopy in the Offspring

Edith M. Hessel, Dynavax Technologies, USA
A Restricted Subset of Dendritic Cells Captures Airborne Allergens and Retains the Capacity to Activate Antigen-Specific T Cells Long after the Last Exposure

Ann E. Welch, American Red Cross/Holland Lab, USA
Contribution of the IL-4Ra to Inflammatory Responses in the Lung

David J. Klinke, Entelos, Inc., USA
Contributions of Th2 Cytokines to Airway Hyperresponsiveness in Asthma

Douglas A. Kuperman, Northwestern University, USA
Direct Effects of IL-13 on Epithelial Cells Cause Airway Hyperreactivity and Mucus Production in the Absence of Inflammation

Claudia Zuany-Amorim, Pfizer Global Research & Development, France
Suppression of Airway Eosinophilia by Allergen Specific, IL-10-Producing Regulatory CD4+ T Cells from Heat-Killed Mycobacterium vaccae-Treated Mice

Joel Tocker, Janssen R&D, USA
Comparative Effects of Blocking either IL-4 or IL-4R in a Mouse Model of Asthma

16:30—17:00
Coffee & Snacks Available

Promenade
17:00—19:00
Immune Mechanisms in Asthma (Session I). Session Sponsored by AstraZeneca R&D, Lund.
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Robert L. Coffman, Dynavax Technologies, USA

Stefanie N. Vogel, University of Maryland, USA
New Insights into Differential Gene Expression Induced by Toll-Like Receptors (TLRs) TLR2 vs. TLR4

Bali Pulendran, Stanford University School of Medicine, USA
Sensing Pathogens and Tuning Immune Responses with Dendritic Cells

Muriel Moser, Université Libre de Bruxelles, Belgium
Dendritic Cell Regulation of Th1/Th2 Development

19:00—20:00
Welcome Mixer

Promenade
20:00—22:00
Poster Session 1: Immunologic Origins of Asthma/Immune Mechanisms in Asthma

Mesa C

SUNDAY, FEBRUARY 10

07:00—08:00
Breakfast

Chamisa
08:00—11:30
Immune Mechanisms in Asthma (Session II) Session Sponsored by AstraZeneca R&D, Lund
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* A. Barry Kay, National Heart and Lung Institute, UK

K. Frank Austen, Harvard Medical School, USA
Mast Cell Effector Mechanisms

Soman N. Abraham, Duke University Medical Center, USA
Caveolae Mediated Uptake of Particulate Allergens and Bacteria by Mast Cells

Donald W. MacGlashan, Johns Hopkins University, USA
IgE and its Receptor

Achsah D. Keegan, University of Maryland School of Medicine, USA
Signaling by the IL-4Ralpha

Craig Gerard, Children's Hospital Harvard University, USA
Complement in Asthma

09:20—09:40
Coffee Break

Promenade
16:30—17:00
Coffee & Snacks Available

Promenade
17:00—19:00
Environmental Factors and Epidemiology of Asthma (Session I)
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Jeffrey M. Drazen, New England Journal of Medicine, USA

Jonathan M. Samet, Johns Hopkins University, USA
The Changing Epidemiology of Asthma: What is the Environment's Role?

Stephen T. Holgate, Southampton General Hospital, UK
Airway Epithelium and Responses to Environmental Factors

Thomas A.E. Platts-Mills, University of Virginia Health System, USA
The Modified Th2 Response (IgG/IgG4) as a Mechanism of Tolerance to Inhaled Allergens

19:00—20:00
Welcome Mixer

Promenade

MONDAY, FEBRUARY 11

07:00—08:00
Breakfast

Chamisa
08:00—11:00
Environmental Factors and Epidemiology of Asthma (Session II)
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Erika von Mutius, University Children's Hospital, Munich, Germany

Scott T. Weiss, Brigham and Women's Hospital, USA
The Natural History of Asthma: Early Childhood Events and Asthma in Later Life: The Obesity/Growth Story

Fernando D. Martinez, University of Arizona, USA
Gene-Environment Interactions

Diane R. Gold, Brigham and Women's Hospital, USA
Environment, The Early Childhood Immune Response, and Asthma

Charles G. Plopper, University of California, Davis, USA
Allergen-Ozone Interactions in Non-Human Primates

09:20—09:40
Coffee Break

Promenade
11:00—13:00
Poster Setup

Mesa C
13:00—22:00
Poster Viewing

Mesa C
14:30—16:30
Workshop 2

Mesa A-B
* Thomas A.E. Platts-Mills, University of Virginia Health System, USA

Susan J. Wilson, University of Southampton, UK
Advanced Glycation End-Products in the Pathogenesis of Airway Remodeling in Asthma

Kenji Izuhara, Saga Medical School, Japan
Analysis of Novel Disease-Related Genes in Bronchial Asthma

Philip J. Cooper, St George's, University of London, UK
Reduced Risk of Atopy Among School Age Children Infected with Geohelminth Parasites in a Rural Area of the Tropics

Michael J. Evans, University of California, Davis, USA
Perlecan and Fibroblast Growth Factor-2 Immunoreactivity During Postnatal Development and Remodeling of the Basement Membrane Zone of Rhesus Monkeys Exposed to Allergen and Ozone

Miriam F. Moffatt, University of Oxford, UK
Epigenetic Effects on Association of Atopic Disease to the SPINK5 Gene

Benjamin J. Marsland, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Switzerland
Influenza A Induced Memory CD8+ T Cells Inhibit Allergen-induced CD4+ T Cell Migration and Effector Function

Andrea Keane-Myers, National Institutes of Health, USA
Alterations in Allergic Inflammation Following Ascaris Infection

Peter D. Sly, TVWT Telethon Institute for Child Health, Australia
Measurement of Airway Tone in vivo to Assess Post-Viral Wheeze Mechanisms

16:30—17:00
Coffee & Snacks Available

Promenade
17:00—19:00
Genetics of Asthma
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Stephen T. Holgate, Southampton General Hospital, UK

William O.C. Cookson, Wellcome Trust Centre for Human Genetics, UK
Genetics of Asthma: Recent Advances

Carole Ober, University of Chicago, USA
Gene-Gene and Gene-Environment Interactions and the Genetics of Asthma

Jeffrey M. Drazen, New England Journal of Medicine, USA
Pharmacogenetics of Asthma

19:00—20:00
Welcome Mixer

Promenade
20:00—22:00
Poster Session 2: Environmental Factors and Epidemiology of Asthma/Genetics and Therapeutics of Asthma

Mesa C

TUESDAY, FEBRUARY 12

07:00—08:00
Breakfast

Chamisa
08:00—10:45
Novel Therapeutic Approaches (Session I). Session Sponsored by Merck & Co., Inc.
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Achsah D. Keegan, University of Maryland School of Medicine, USA

Lars Jacobsen, ALK-Abello A/S, Denmark
Immunotherapy to Prevent Asthma in Children

Arthur M. Krieg, Checkmate Pharmaceuticals, USA
Shifting from Th2 to Th1 with Immune Stimulatory CpG DNA

A. Barry Kay, National Heart and Lung Institute, UK
Tolerance Induction by T Cell Peptide Immunotherapy

09:20—09:40
Coffee Break

Promenade
16:30—17:00
Coffee & Snacks Available

Promenade
17:00—19:00
Novel Therapeutic Approaches (Session II). Session Sponsored by Merck & Co., Inc.
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Arthur M. Krieg, Checkmate Pharmaceuticals, USA

Robert W. Egan, Schering-Plough Research Institute, USA
Eosinophils in Asthma

Larry Borish, University of Virginia Medical Center, USA
Interleukin-4 Antagonism in the Treatment of Asthma

Robert L. Coffman, Dynavax Technologies, USA
Modulating Th2 Responses in Asthma with Immunostimulatory DNA

19:00—20:00
Welcome Mixer

Promenade
20:00—23:00
Entertainment

Mesa Ballroom

WEDNESDAY, FEBRUARY 13

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1 R13 AI50897-01




We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676