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This meeting took place in 2002



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Stem Cells: Origins, Fates and Functions (X3)


Organizer(s) Fred H. Gage, Brigid L.M. Hogan and Yuh-Nung Jan
March 17—23, 2002
Keystone Resort • Keystone, Colorado USA
Abstract Deadline: Nov 16, 2001
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Jan 17, 2002


Summary of Meeting:
Pluripotent stem cells give rise to all cells of an organism. All multicellular organisms are derived from stem cells. Stem cells exist in most organs of adult species and give rise to progeny throughout life. The origin and nature of the most primitive stem cells remains elusive, though population studies confirm their existence. The intrinsic and extrinsic factors that regulate cell fate determination are only presently being studied in detail. There is great promise for the use of stem cells in tissue repair and disease, but basic knowledge of underlying mechanism of proliferation, migration, and differentiation are lacking. By comparing the knowledge acquired from different species, common principles will likely emerge. By delineating the similarities in the properties of stem cells derived from different ages and different tissue, a convergent conceptual framework will provide coherence and guidance for future studies. Evaluation of the current application of stem cells for diagnosis and therapy should provide a measure of how much progress has been made, and is needed.

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Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SUNDAY, MARCH 17

16:00—19:00
Registration

Shavano Foyer
18:15—19:15
Welcome

Shavano Foyer
19:15—19:30
Orientation

Shavano/Torreys
19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Shavano/Torreys
Rudolf Jaenisch, Whitehead Institute for Biomedical Research, USA
Nuclear Cloning and Reprogramming and Reprogramming of the Genome

19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Red Cloud
Nicole M. Le Douarin, Institut d'Embryologie Cellulaire et Moleculaire, France
Patterning the Neural Crest Derived Facial Skeleton: Roles of Hox Genes and of the Endoderm


MONDAY, MARCH 18

07:00—08:00
Breakfast

Longs/Quandary Peak
08:00—11:00
Species Diversity
Meeting has ended...abstracts no longer viewable online.

Shavano/Torreys
* Brigid L. M. Hogan, Duke University Medical Center, USA

Hans R. Bode, University of California, Irvine, USA
Stem Cells in Hydra

Alejandro Sánchez Alvarado, Stowers Institute for Medical Research/HHMI, USA
Stem Cells in Planarians: The Neoblasts of Schmidtea mediterranea

Detlef Weigel, Max Planck Institute for Developmental Biology, Germany
A Link Between Stem Cell Regulation and Floral Patterning

Romualdo Ciau-Uitz, University of Nottingham, UK
Short Talk: The Origins and Development of Haematopoietic Stem Cells in Xenopus

Diana J. Laird, University of California, San Francisco, USA
Short Talk: Somatic Stem Cells in a Protochordate

08:00—11:00
Neural Tube Patterning
Meeting has ended...abstracts no longer viewable online.

Red Cloud
* Hermann Rohrer, Max-Planck-Institute for Brain Research, Germany

Bennett G. Novitch, Columbia University College of Physicians & Surgeons, USA
Regulation of Motor Differentiation by the bHLH Repressor Olig2

Andrew P. McMahon, Harvard University, USA
Wnt and Hedgehog Signaling in the CNS

Kristin Bruk Artinger, Harvard Medical School, USA
Short Talk: Cell Fate Determination at the Neural Plate Border in Zebrafish and Xenopus

Jane E. Johnson, University of Texas Southwestern Medical Center, USA
Regulation and Role of bHLH Factors in Dorsal Neural Tube

Cynthia Lance-Jones, University of Pittsburgh School of Medicine, USA
Short Talk: Programming Hox Patterns in the Avian Lumbosacral Spinal Cord

09:20—09:40
Coffee Break

Shavano Foyer/Lobby
11:00—12:00
Workshop Announcing Joint NIH Programs Supporting Stem Cell Research

Shavano/Torreys
Gregory J. Downing, National Institutes of Health, USA

Arlene Chiu, NINDS, National Institutes of Health, USA

Sheryl Sato, National Institutes of Health, USA

Richard J. Tasca, National Institutes of Health, USA

Nancy L. Freeman, National Institutes of Health, USA

John W. Thomas, NHLBI, National Institutes of Health, USA

11:00—13:00
Poster Setup

Grays Peak
13:00—22:00
Poster Viewing

Grays Peak
04:30—17:00
Coffee & Snacks Available

Shavano Foyer/Lobby
17:00—19:00
Early Pluripotency and Self Renewal
Meeting has ended...abstracts no longer viewable online.

Shavano/Torreys
* Margaret T. Fuller, Stanford University, USA

Austin Smith, University of Cambridge, UK
Self-Renewal and Differentiation Processes in Pluripotent Embryo-Derived Stem Cells

K. John McLaughlin, University of Pennsylvania, USA
Disruption of Pluripotency in Mouse Clones

Daniele Jacqueline Pralong, Adelaide University, Australia
Short Talk: Nuclear Transfer to Mouse ES-Like Cells: Pre- and Post-Fusion Enucleation

Janice Ann Lansita, Massachusetts Institute of Technology, USA
Short Talk: Demonstration of Immortal DNA Strand Co-Segregation in Cells that Cycle with Asymmetric Stem Cell Kinetics

Trish A. Labosky, National Institutes of Health, USA
Short Talk: Requirement for Foxd3 in Establishing Pluripotent Stem Cells of the Early Mouse Embryo

Akihiko Okuda, Saitama Medical School Research Center for Genomic Medicine, Japan
Short Talk: Unique DNA Binding Specificity of Oct-3/4 and its Function for Maintaining ES Cells in Pluripotent State

17:00—19:00
Neural Induction
Meeting has ended...abstracts no longer viewable online.

Red Cloud
* Martin C. Raff, University College London, UK

Richard Harland, University of California, Berkeley, USA
Neural Patterning in Xenopus

Kate G. Storey, University of Dundee, UK
Molecular Mechanisms Underlying the Generation of the Chick Spinal Cord

Claudio D. Stern, University College London, UK
Molecular Dissection of Neural Induction in the Chick Embryo

19:00—20:00
Welcome Mixer

Grays Peak
20:00—22:00
Poster Session 1

Grays Peak

TUESDAY, MARCH 19

07:00—08:00
Breakfast

Longs/Quandary Peak
08:00—11:00
Instructive Signaling (Joint)
Meeting has ended...abstracts no longer viewable online.

Shavano/Torreys
* Yuh-Nung Jan, University of California, San Francisco, USA

David J. Anderson, California Institute of Technology, USA
Neural Crest Stem Cells

Elaine V. Fuchs, HHMI/Rockefeller University, USA
Epithelial Stem Cells in the Skin and Their Lineages

Laura Gammill, California Institute of Technology, USA
A Genomic Analysis of Neural Crest Induction

Weimin Zhong, Yale University, USA
Short Talk: Mouse numb and numblike are Essential Genes for Maintaining Neural Stem/Progenitor Cells during Embryogenesis

Sumana Datta, Texas A & M University, USA
Short Talk: Perlecan Modulates FGF and Hh Signaling to Control Stem Cell Division

09:20—09:40
Coffee Break

Shavano Foyer/Lobby
11:00—13:00
Poster Setup

Grays Peak
13:00—22:00
Poster Viewing

Grays Peak
16:30—17:00
Coffee & Snacks Available

Shavano Foyer/Lobby
17:00—19:00
External Regulation of Stem Cell Behavior
Meeting has ended...abstracts no longer viewable online.

Shavano/Torreys
* David J. Anderson, California Institute of Technology, USA

Allan C. Spradling, HHMI/Carnegie Institute, USA
Stem Cells Niches Regulate Cell Production During Drosophila Oogenesis

Fred (Rusty) H. Gage, The Salk Institute for Biological Studies, USA
Neurogenesis in the Adult Brain

Yuh-Nung Jan, University of California, San Francisco, USA
Local Environmental Control of Neuroblasts

17:00—19:00
Axon Guidance
Meeting has ended...abstracts no longer viewable online.

Red Cloud
* Marie T. Filbin, Hunter College, USA

Lynn T. Landmesser, Case Western Reserve University, USA
Selective Fasciculation and the Early Expression of Multiple Motoneuron Subtype Differences during the Formation of Spinal Motor Circuits

Yi Rao, Peking University, China
Temporal and Spatial Control of Neuronal Migration

Chenghua Gu, Harvard Medical School, USA
The Roles of Secreted Semaphorins and Their Receptors During Nervous System Development

19:00—20:00
Welcome Mixer

Grays Peak
20:00—22:00
Poster Session 2

Grays Peak

WEDNESDAY, MARCH 20

07:00—08:00
Breakfast

Longs/Quandary Peak
08:00—11:00
Origins and Niches
Meeting has ended...abstracts no longer viewable online.

Shavano/Torreys
* Allan C. Spradling, HHMI/Carnegie Institute, USA

Fiona M. Watt, King's College London School of Medicine, UK
Regulation of Stem Cell Fate in Mammalian Epidermis

Margaret T. Fuller, Stanford University, USA
Specification of Stem Cell Self-Renewal by a Signals from a Support Cell Niche

Helen M. Blau, Stanford University, USA
Adult Stem Cells: From Bone Marrow to Brain and Brawn

Niels Geijsen, Massachusetts General Hospital, USA
Short Talk: Isolation of Spermatogonial Stem Cells Using Flow Cytometry

Haifan Lin, Yale University, USA
Short Talk: A Common Signaling Center Regulates the Division of Two Types of Resident Stem Cells that Maintain the Drosophila Ovary

Robert E. Braun, The Jackson Laboratory, USA
Short Talk: Spermatogonial Stem Cell Loss in the Murine Luxoid Mutant

08:00—11:00
Neural Crest Formation and Migration
Meeting has ended...abstracts no longer viewable online.

Red Cloud
* Robb Krumlauf, Stowers Institute for Medical Research, USA

Carole LaBonne, Northwestern University, USA
Regulation of Neural Crest Formation in Xenopus

Tal Burstyn-Cohen, Hebrew University Jerusalem, Israel
Short Talk:

Scott E. Fraser, California Institute of Technology, USA
Intravital Imaging of Neural Crest Cells and Neural Progenitors

M. Angela Nieto, Instituto de Neurociencias de Alicante, CSIC-UMH, Spain
The Snail Gene Family and the Evolution of the Neural Crest

09:20—09:40
Coffee Break

Shavano Foyer/Lobby
11:00—13:00
Poster Setup

Grays Peak
13:00—22:00
Poster Viewing

Grays Peak
16:30—17:00
Coffee & Snacks Available

Shavano Foyer/Lobby
17:00—19:00
Prospective Isolation and Characterization
Meeting has ended...abstracts no longer viewable online.

Shavano/Torreys
* Leonard I. Zon, HHMI/Boston Children's Hospital, USA

Margaret A. Goodell, Baylor College of Medicine, USA
Stem Cells from Bone Marrow and Muscle and Differentiation Plasticity

Irving L. Weissman, Stanford University, USA
Biology of Stem and Progenitor Cells

Perry F. Bartlett, Walter and Eliza Hall Institute of Medical Research, Australia
Characteristics of a Neural Stem Cell Isolated from the Adult Brain

17:00—19:00
Neural Crest/Neural Tube Patterning
Meeting has ended...abstracts no longer viewable online.

Red Cloud
* Claudio D. Stern, University College London, UK

Sara C. Ahlgren, California Institute of Technology, USA
Sonic Hedgehog Rescues Cranial Neural Crest Cell Death Induced by Fetal Alcohol Syndrome

Annette Julia Neubüser, Research Institute of Molecular Pathology, Austria
Short Talk: FGF8 is Required for Development of the Facial Skeleton

Robb Krumlauf, Stowers Institute for Medical Research, USA
Hox Genes and Mechanisms Regulating the Formation, Migration and Patterning of Cranial Neural Crest Cells in Head Development

Marthe J. Howard, Medical College of Ohio, USA
Short Talk: Molecular Mechanisms of the bHLH Factor dHAND in the Differentiation of Neural Crest-Derived Sympathetic Neurons

19:00—20:00
Welcome Mixer

Grays Peak
20:00—22:00
Poster Session 3

Grays Peak

THURSDAY, MARCH 21

07:00—08:00
Breakfast

Longs/Quandary Peak
08:00—11:00
Hematopoiesis
Meeting has ended...abstracts no longer viewable online.

Shavano/Torreys
* Irving L. Weissman, Stanford University, USA

Leonard I. Zon, HHMI/Boston Children's Hospital, USA
Stem Cell Regulation in the Zebrafish

Ihor R. Lemischka, Icahn School of Medicine at Mount Sinai, USA
Stem Cells to Genes and Back

John E. Dick, Princess Margaret Cancer Centre, Canada
Complexity of the Human Stem Cell Compartment

Atsushi Asakura, University of Minnesota, Medical School, USA
Short Talk: Myogenic and Hematopoietic Differentiation of Skeletal Muscle Derived Adult Stem Cells

Masatsugu Ema, Institute of Basic Medical Sciences, Tsukuba University, Japan
Sort Talk: A Common Progenitor for Hematopoietic, Endothelial and Vascular Smooth Muscle Cells: Cell Fate Control by the SCL/TAL1 Transcription Factor

Morteza Bonyadi, Samuel Lunenfeld Research Institute, Canada
Short Talk: Stem Cell Antigen 1 (Sca-1) is Required for Normal Development of Osteoprogenitors

08:00—11:00
Spinal Cord Regeneration and Motor Neuron Growth
Meeting has ended...abstracts no longer viewable online.

Red Cloud
* Lynn T. Landmesser, Case Western Reserve University, USA

Marie T. Filbin, Hunter College, USA
Overcoming Inhibitors of Regeneration in Myelin

Lisa J. McKerracher, Universite de Montreal and BioAxone Therapeutic Inc., Canada
Inactivation of Rho After CNS Injury to Overcome Growth Inhibition: Use of New C3-Like Compounds.

Catherine E. Krull, University of Michigan, USA
Short Talk: Eph-Ephrin Interactions in Motor Axon Pathfinding

Martin E. Schwab, University of Zürich, Switzerland
The Role of Nogo-A in Axonal Regeneration and Plasticity

Kimberly L. Cooper, , USA
Short Talk: Autonomous and Non-Autonomous Functions for Hox/Pbx in Cranial Motor Neuron Development

09:20—09:40
Coffee Break

Shavano Foyer/Lobby
11:00—13:00
Poster Setup

Grays Peak
13:00—22:00
Poster Viewing

Grays Peak
16:30—17:00
Coffee & Snacks Available

Shavano Foyer/Lobby
17:00—19:00
Cross System Potentiality
Meeting has ended...abstracts no longer viewable online.

Shavano/Torreys
* John E. Dick, Princess Margaret Cancer Centre, Canada

Catherine M. Verfaillie, University of Minnesota, USA
Multipotent Bone Marrow Derived Progenitor Cells

Darwin J. Prockop, Texas A&M Health Science Center, USA
Isolation and Characterization of Adult Stem Cells from Human Bone Marrow Stroma (MSCs)

Lijun Yang, University of Florida College of Medicine, USA
Short Talk: In vitro Transdifferentiation of Adult Rat Hepatic Stem Cells into Pancreatic Endocrine Cells

Mark F. Pittenger, University of Maryland Medical Center, USA
Short Talk: Applications of Adult Human Mesenchymal Stem Cells

17:00—19:00
Nervous System Development and Repair
Meeting has ended...abstracts no longer viewable online.

Red Cloud
* Richard Harland, University of California, Berkeley, USA

Martin C. Raff, University College London, UK
Asymmetrical Cell Division and Numb Segregation in the Developing Mammalian Retina

Almudena Ramon-Cueto, Spanish Council for Scientific Research, Spain
Repair of Injured Mammalian Spinal Cords by Olfactory Ensheathing Glia Transplants

Hermann Rohrer, Max-Planck-Institute for Brain Research, Germany
Specification of Noradrenergic and Cholinergic Neuronal Phenotypes in the Autonomic Nervous System

19:00—20:00
Welcome Mixer

Grays Peak
20:00—22:00
Poster Session 4

Grays Peak

FRIDAY, MARCH 22

07:00—08:00
Breakfast

Longs/Quandary Peak
08:00—11:00
Neural Diversity (Joint)
Meeting has ended...abstracts no longer viewable online.

Shavano/Torreys
* Fred (Rusty) H. Gage, The Salk Institute for Biological Studies, USA

Derek J. Van Der Kooy, University of Toronto, Canada
How Many Types of Neural Stem Cells Does it Take to Make a Mammalian Brain

Arturo Alvarez-Buylla, University of California, San Francisco, USA
Origin of Neural Stem Cells in the Adult Brain

Ronald D. McKay, Lieber Institute for Brain Development, USA
From Stem Cells to Synapses

Jonas Frisén, Karolinska Institutet, Sweden
Generation of Nerons from Stem Cells in the Adult Brain

09:20—09:40
Coffee Break

Shavano Foyer/Lobby
16:30—17:00
Coffee & Snacks Available

Shavano Foyer/Lobby
17:00—19:00
Human Stem Cells and Applications (Joint). Session Sponsored by the Juvenile Diabetes Research Foundation.
Meeting has ended...abstracts no longer viewable online.

Shavano/Torreys
* Fiona M. Watt, King's College London School of Medicine, UK

James A. Thomson, Morgridge Institute for Research, University of Wisconsin, USA
Human Embryonic Stem Cells

Andrew L. Laslett, Commonwealth Scientific and Industrial Research Organization, Australia
Short Talk: Characterisation and Isolation of Subpopulations of Human Embryonic Stem Cells

Nissim Benvenisty, Hebrew University of Jerusalem, Israel
Short Talk: Differentiation and Genetic Manipulation of Human Embryonic Stem Cells

Yutaka Hanazono, Jichi Medical School, Japan
Short Talk: Highly Efficient Gene Transfer into Primate Embryonic Stem Cells with a Simian Lentivirus Vector

19:00—20:00
Welcome Mixer

Longs/Quandary Peak
20:00—23:00
Entertainment

Longs/Quandary Peak

SATURDAY, MARCH 23

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1 R13 NS42933-01




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