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This meeting took place in 2003



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Axonal Connections: Molecular Cues for Development and Regeneration (C3)


Organizer(s) John G. Flanagan, Marc Tessier-Lavigne and Stephen M. Strittmatter
February 13—17, 2003
Keystone Resort • Keystone, Colorado USA
Abstract Deadline: Oct 14, 2002
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Dec 13, 2002

Sponsored in part by The Director's Sponsor Fund

Summary of Meeting:
The functioning of the nervous system depends on its complex pattern of connections. Axonal connections are initially set up during development by cues, which guide axons along specific pathways, and then specify connection sites within the target region. In recent years, dramatic progress has been made in identifying such cues molecularly. Based on this progress, current studies are elucidating the molecular logic of extracellular signals that set up connectivity, as well as intracellular pathways that interpret these signals. In the adult central nervous system, damaged axonal connections do not regenerate, even though peripheral nerves can regenerate efficiently. This is due at least in part to CNS inhibitors, some of which have now been cloned. This meeting will bring together the fields of development and regeneration, with the goal of facilitating synergistic overlaps in techniques, molecules and biology. Topics will include basic research on molecular cues, and resulting new approaches toward therapeutic axon repair.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


THURSDAY, FEBRUARY 13

15:00—19:00
Registration

Longs Peak Foyer
18:15—19:15
Welcome Reception

Longs Peak Foyer
19:15—19:30
Orientation

Grays Peak 1-2

FRIDAY, FEBRUARY 14

07:00—08:00
Breakfast

Longs Peak
08:00—11:00
Pathway Selection and Choice Points
Meeting has ended...abstracts no longer viewable online.

Grays Peak 1-2
* Larry Zipursky, University of California, Los Angeles, USA

Marc Tessier-Lavigne, Stanford University, USA
Mechanisms of Axon Guidance and Regeneration in the Spinal Cord

Douglas S. Campbell, RIKEN Brain Science Institute, Japan
Pathways that Mediate Chemotropic Responses in Retinal Growth Cones

David L. Van Vactor, Harvard Medical School, USA
Signaling Mechanisms that Regulate Neuronal Morphogenesis in Drosophila

Liqun Luo, Stanford University, USA
Mechanisms of Axon Pruning in Drosophila Brain

09:20—09:40
Coffee Break

Grays Peak Foyer
11:00—13:00
Poster Setup

Quandary 1-2
13:00—22:00
Poster Viewing

Quandary 1-2
16:00—16:30
Coffee & Snacks Available

Grays Peak Foyer
16:30—19:00
Target Recognition
Meeting has ended...abstracts no longer viewable online.

Grays Peak 1-2
* John G. Flanagan, Harvard Medical School, USA

Larry Zipursky, University of California, Los Angeles, USA
Target Recognition in the Drosophila Nervous System

Dennis D.M. O'Leary, The Salk Institute, USA
Regulation of Topographic Maps in the Developing Visual System

Zhihua Zou, Fred Hutchinson Cancer Research Center, USA
Odor Codes and Odor Maps

C. Ron Yu, Stowers Institute for Medical Research, USA
Short Talk: The Requirement of Electrical Activity for Olfactory Axon Targeting

19:00—20:00
Social Hour

Quandary 1-2
20:00—22:00
Poster Session 1

Quandary 1-2

SATURDAY, FEBRUARY 15

07:00—08:00
Breakfast

Longs Peak
08:00—11:00
Inhibitors of Regeneration
Meeting has ended...abstracts no longer viewable online.

Grays Peak 1-2
* Marc Tessier-Lavigne, Stanford University, USA

Martin E. Schwab, University of Zürich, Switzerland
Enhancing Regeneration and Compensatory Axon Growth in Injured Adult CNS

Marie T. Filbin, Hunter College, USA
Manipulation of Signaling Mechanisms to Overcome Inhibitors of Regeneration in Myelin

Jerry Silver, Case Western Reserve University, USA
Axon Regeneration Beyond the Glial Scar

Stephen M. Strittmatter, Yale University, USA
Inhibitors of Axon Regeneration in the CNS

David Evan Goldberg, Children's Hospital Boston, USA
Short Talk: Rewiring the Brain after Stroke: Optimizing Inosine Treatment to Maximize Functional Outcome

09:20—09:40
Coffee Break

Grays Peak Foyer
11:00—13:00
Poster Setup

Quandary 1-2
13:00—22:00
Poster Viewing

Quandary 1-2
16:00—16:30
Coffee & Snacks Available

Grays Peak Foyer
16:30—19:00
Inhibitory Cues in Development
Meeting has ended...abstracts no longer viewable online.

Grays Peak 1-2
* Stephen M. Strittmatter, Yale University, USA

John G. Flanagan, Harvard Medical School, USA
Regulation of the Response to Guidance Cues

Rüdiger Klein, Max Planck Institute of Neurobiology, Germany
Ephrins and Eph Receptors in Neural Development and Synaptic Plasticity

Alex L. Kolodkin, Johns Hopkins University School of Medicine, USA
Semaphorin-Mediated Repulsive Guidance

Frank B. Gertler, Massachusetts Institute of Technology, USA
Regulation of Cell and Growth Cone Locomotion

19:00—20:00
Social Hour

Quandary 1-2
20:00—22:00
Poster Session 2

Quandary 1-2

SUNDAY, FEBRUARY 16

07:00—08:00
Breakfast

Longs Peak
08:00—11:00
Pathways Downstream of Axonal Receptors
Meeting has ended...abstracts no longer viewable online.

Grays Peak 1-2
* Michael E. Greenberg, Harvard Medical School, USA

Mu-ming Poo, Institute of Neuroscience, CAS, China
Growth Cone Turning in Gradients of Diffusible Factors: Some Common Features in Signal Transduction

Lisa J. McKerracher, Universite de Montreal and BioAxone Therapeutic Inc., Canada
Reversal of Rho Activation after CNS Injury to Promote Axon Regeneration and Neuroprotection

Zhigang He, Children's Hospital, Boston, USA
Signaling Mechanisms of Axon Regeneration Inhibition by CNS Myelin

Michael E. Greenberg, Harvard Medical School, USA
Signal Transduction Mechanisms In The Developing Nervous System

Tony Koleske, Yale University, USA
Short Talk: Abl Family Kinases Regulate Dendrite Branching

09:20—09:40
Coffee Break

Grays Peak Foyer
16:00—16:30
Coffee & Snacks Available

Grays Peak Foyer
16:30—19:00
Signals in Degeneration and Regeneration
Meeting has ended...abstracts no longer viewable online.

Grays Peak 1-2
* Martin E. Schwab, University of Zürich, Switzerland

Ben A. Barres, Stanford University, USA
Amacrine-Signaled Loss of Intrinsic Axon Growth Ability by Retinal Ganglion Cells

Pico Caroni, Friedrich Miescher Institute, Switzerland
Intrinsic Competence for Anatomical Plasticity and Axon Growth

Clifford J. Woolf, Children's Hospital, USA
Intrinsic Determinants of Axonal Regeneration

Stephen B. McMahon, King's College London, UK
Repair of Spinal Cord Injury

19:00—20:00
Social Hour

Grays Peak 2-3
20:00—23:00
Entertainment

Grays Peak 2-3

MONDAY, FEBRUARY 17

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1 R13 NS045340-01




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