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This meeting took place in 2003



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From Stem Cells to Therapy (E3)


Organizer(s) Janet Rossant, David J. Mooney, Margaret A. Goodell and Farshid Guilak
March 29—April 3, 2003
Sheraton Steamboat Resort • Steamboat Springs, Colorado USA
Abstract Deadline: Dec 2, 2002
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Jan 29, 2003

Supported by Keystone Symposia

Summary of Meeting:
Stem cells have generated considerable excitement recently in the scientific, clinical, and public domains. Pluripotent cells derived from early embryos or fetal tissues appear capable of indefinite expansion and have the capacity to differentiate into many cell types. Multipotential stem cells derived from adult tissues are being found in novel niches and have considerably broader differentiation capacity than originally imagined. By 2003 these exciting discoveries will be maturing into a broader understanding of the factors that control stem cell self-renewal, differentiation, and stem cell plasticity, as well as the differences between adult and embryonic stem cells. In order to translate this research into therapeutic applications, the basic biology must be merged with applied aspects of cell and tissue engineering, biomaterials, transplantation biology and delivery systems. This conference will bring together top stem cell biologists, biomedical engineers and clinicians in an interdisciplinary format to discuss the frontiers of stem cells and therapeutic applications. General topics: * stem cells and pluripotency * plasticity of stem cells * environmental signals controlling stem cells * quality control of stem cell growth and differentiation * from stem cells

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SATURDAY, MARCH 29

15:00—19:00
Registration

Foyer
18:15—19:15
Welcome

Foyer
19:15—19:30
Orientation

Sunshine/Mt. Werner
19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Sunshine/Mt. Werner
Robert S. Langer, Massachusetts Institute of Technology, USA
Advances in Tissue Engineering


SUNDAY, MARCH 30

06:30—08:00
Breakfast

3 Saddles/Sevens
08:00—11:00
Stem Cells and Pluripotency. Session Sponsored by The March of Dimes Birth Defects Foundation.
Meeting has ended...abstracts no longer viewable online.

Sunshine/Mt. Werner
* Janet Rossant, Hospital for Sick Children, Canada

Martin F. Pera, , Australia
Human Embryonic Stem Cells: Pluripotent Cells and their Progeny

James A. Thomson, Morgridge Institute for Research, University of Wisconsin, USA
Genetic Manipulation of Human Embryonic Stem Cells

Cecilia Annerén, Harvard University, USA
Short Talk: Possible Role for the Src Family Member cYes in the Maintenance of Undifferentiated Embryonic Stem Cells

Thomas P. Zwaka, Icahn School of Medicine at Mount Sinai, USA
Short Talk: Gene Targeting of Oct4 in Human ES Cells Reveals that Both Self-Renewal and Differentiation Occurs Through Symmetric Cell Division

Freda D. Miller, Hospital for Sick Children, Canada
Accessible Stem Cells from Mammalian Dermis

09:20—09:40
Coffee Break

Foyer
11:00—13:00
Poster Setup

Storm Peak/Twilight/Rainbow
13:00—22:00
Poster Viewing

Storm Peak/Twilight/Rainbow
16:30—17:00
Coffee & Snacks Available

Foyer
17:00—19:00
Stem Cell Differentiation
Meeting has ended...abstracts no longer viewable online.

Sunshine/Mt. Werner
Kyunghee Choi, Washington University, USA
From ES to Hematopoietic and Endothelial Cells

Hanna K.A. Mikkola, University of California, Los Angeles, USA
Short Talk: Hematopoietic Stem Cells Retain Long Term Repopulating Activity and Multipotency in the Absence of Stem Cell Leukemia (SCL/tal1) Gene

Albrecht M. Müller, Universitaet Wuerzburg, Germany
Short Talk: Enhancing the Development Potentials of Somatic Stem Cells by Epigentic Modification

* Melissa K. Carpenter, Robarts Research Institute, Canada
Human Embryonic Stem Cells: Characterization and Differentiation

Ronald S. Goldstein, Bar-Ilan University, Israel
Short Talk: Integration and Differentiation of Human Embryonic Stem Cells Transplanted to the Chick Embryo

19:00—20:00
Social Hour

Foyer
19:00—22:00
Poster Session 1: Basic Biology of Stem Cells

Storm Peak/Twilight/Rainbow

MONDAY, MARCH 31

06:30—08:00
Breakfast

3 Saddles/Sevens
08:00—11:00
Adult Stem Cell Plasticity
Meeting has ended...abstracts no longer viewable online.

Sunshine/Mt. Werner
Jonas Frisén, Karolinska Institutet, Sweden
CNS Stem Cells and Plasticity

* Margaret A. Goodell, Baylor College of Medicine, USA
Stem Cells, SP Cells and Potential Differentiation Plasticity

Daniel A. Peterson, Rosalind Franklin University, Chicago Medical School, USA
Short Talk: Impaired Capacity of the Aged Brain to Support Neurogenesis

Fulvio Mavilio, Genethon, France
Short Talk: Myogenic Differentiation of CD45+ Committed Hematopoietic Stem/Progenitor Cells

Xin Wang, Oregon Health & Science University, USA
Short Talk: Cell Fusion is the Principal Source of Bone-Marrow Derived Hepatocytes

Fabio M.V. Rossi, University of British Columbia, Canada
Clonal Analysis of Myogenic Potential of Hematopoietic Stem Cells

09:20—09:40
Coffee Break

Foyer
11:00—13:00
Poster Setup

Storm Peak/Twilight/Rainbow
13:00—22:00
Poster Viewing

Storm Peak/Twilight/Rainbow
16:30—17:00
Coffee & Snacks Available

Foyer
17:00—19:15
The Stem Cell Niche
Meeting has ended...abstracts no longer viewable online.

Sunshine/Mt. Werner
* Freda D. Miller, Hospital for Sick Children, Canada

Fiona M. Watt, King's College London School of Medicine, UK
The Stem Cell Niche in Mammalian Epidermis

Margaret T. Fuller, Stanford University, USA
Regulation of Asymmetric Division of Germline Stem Cells in the Niche

Martin Dym, Georgetown University School of Medicine, USA
Short Talk: Male Germ Line Stem Cells: A Novel Stem Cell Line

Thaddeus S. Stappenbeck, Washington University School of Medicine, USA
Short Talk: Molecular Features of Adult Mouse Small Intestinal Epithelial Progenitors

Linheng Li, Stowers Institute for Medical Research, USA
Short Talk: BMP Signaling Through BMPR1A Negatively Controls Stem Cell Compartments in Bone Marrow, Hair Follicle, and Instestine

Sheng Ding, Gladstone Institute of Cardiovascular Disease and University of California, San Francisco, USA
Short Talk: Exploring Mammalian Regenerations: From Small Molecules and Genes to Underlining Mechanisms

19:15—20:15
Social Hour

Foyer
19:15—22:15
Poster Session 2: Manipulation and Modulation of Stem Cells

Storm Peak/Twilight/Rainbow

TUESDAY, APRIL 1

06:30—08:00
Breakfast

3 Saddles/Sevens
08:00—11:00
Manipulating Stem Cells by Controlling Their Environment
Meeting has ended...abstracts no longer viewable online.

Sunshine/Mt. Werner
* David J. Mooney, Harvard University, USA

George Q. Daley, HHMI/Boston Children's Hospital, USA
Hematopoietic Differentiation from Embryonic Stem Cells

Jeffrey M. Gimble, Tulane University School of Medicine, USA
Adipose Derived Adult Stem (ADAS) Cells

Hal E. Broxmeyer, Indiana University School of Medicine, USA
Homing, Mobilization and Survival of Hematopoietic Stem and Progenitor Cells

Patrick Seale, University of Pennsylvania, USA
Short Talk: Wnt Signaling Activates the Myogenic Recruitment of CD45+ Adult Stem Cells during Muscle Regeneration

Tannishtha Reya, University of California, San Diego, USA
Short Talk: A Role for Wnt Signaling in Hematopoietic Stem Cell Self-Renewal

Steven A. Goldstein, University of Michigan, USA
Mechanical Influences on Cell Populations in vitro and in vivo

09:20—09:40
Coffee Break

Foyer
11:00—13:00
Poster Setup

Storm Peak/Twilight/Rainbow
13:00—22:00
Poster Viewing

Storm Peak/Twilight/Rainbow
14:30—16:30
Workshop: Regulatory and Commercial Issues of Stem Cell Research and Application

Sunshine/Mt. Werner
* Janet Rossant, Hospital for Sick Children, Canada

Arlene Chiu, NINDS, National Institutes of Health, USA
NIH Support for Human Embryonic Stem Cell Research

Donald W. Fink, Jr., CBER, U.S. Food and Drug Administration, USA
Stem Cells and the FDA: Regulatory Considerations for Proceeding to Clinical Trials

Ann S. Tsukamoto, , USA
Commercialization of Stem Cells: Opportunities and Challenges

16:30—17:00
Coffee & Snacks Available

Foyer
17:00—19:00
Critical Issues for Therapeutic Use of Stem Cells
Meeting has ended...abstracts no longer viewable online.

Sunshine/Mt. Werner
* Irving L. Weissman, Stanford University, USA
Biology of Stem and Progenitor Cells

Micha Drukker, Hebrew University of Jerusalem, Israel
Short Talk: Immunological Properties of Human Embryonic Stem Cells - Implications for Cell Based Therapeutics

Jonathan N. Mansbridge, Tecellact LLC and Medical Devices Consultant, USA
Tissue Culture Engineering of Stem Cells

Peter W. Zandstra, University of Toronto, Canada
Short Talk: Scalable Bioprocesses for the Controlled Differentiation of Embryonic Stem Cells

Farshid Guilak, Duke University Medical Center, USA
Functional Tissue Engineering of Cartilage Using Adipose-Derived Stromal Cells

19:00—20:00
Social Hour

Foyer
19:00—22:00
Poster Session 3: From Stem Cells to Tissue Engineering

Storm Peak/Twilight/Rainbow

WEDNESDAY, APRIL 2

06:30—08:00
Breakfast

3 Saddles/Sevens
08:00—11:00
From Stem Cells to Tissues
Meeting has ended...abstracts no longer viewable online.

Sunshine/Mt. Werner
* Farshid Guilak, Duke University Medical Center, USA

Arnold I. Caplan, Case Western Reserve University, USA
Engineering Tissues using Mesenchymal Stem Cells

Nancy L. Parenteau, Amaranth Bio, Inc., USA
Engineering Tissue with Adult Progenitor Cells

Robert Zweigerdt, Hannover Medical School (MHH), Germany
Short Talk: Clinical Scale Generation of Enriched Embryonic Stem Cell Derived Cardiomyocytes

Anna M. Wobus, Institute of Plant Genetics (IPK), Germany
Short Talk: Expression of Pax4 in Embryonic Stem Cells Promotes Differentiation of Nestin-Positive Progenitor and Insulin-Producing Cells

Joel R. Chamberlain, University of Washington, USA
Short Talk: Targeted Disruption of the Mutant COL1A1 Gene in Mesenchymal Stem Cells from Individuals with Osteogenesis Imperfecta

David J. Mooney, Harvard University, USA
Cell Instructive Materials

09:20—09:40
Coffee Break

Foyer
16:30—17:00
Coffee & Snacks Available

Foyer
17:00—19:00
Clinical Uses for Stem Cells. Session Sponsored by the Juvenile Diabetes Research Foundation International.
Meeting has ended...abstracts no longer viewable online.

Sunshine/Mt. Werner
Gregory S. Korbutt, University of Alberta, Canada
Pancreatic Islet Cells and Diabetes Therapy

Herman H. Vandenburgh, Brown University School of Medicine, USA
Adult Muscle Stem Cells and Gene Therapy

Curt R. Freed, University of Colorado Denver, USA
Cell Transplantation for Parkinson's Disease

20:00—21:00
Social Hour

Foyer
21:00—00:00
Entertainment

Sunshine/Mt. Werner

THURSDAY, APRIL 3

 
Departure


*Session Chair †Invited, not yet responded.



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