Taos Convention Center (meeting only) Floorplan

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This meeting took place in 2003



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Optical Imaging: Applications to Biology and Medicine (C2)


Organizer(s) Dorothea Becker, Scott E. Fraser and Daniel L. Farkas
February 11—16, 2003
Taos Convention Center (meeting only) • Taos, New Mexico USA
Abstract Deadline: Oct 10, 2002
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Dec 11, 2002

Sponsored in part by The Director's Sponsor Fund

Summary of Meeting:
Recent advances in optical imaging have opened new avenues for dynamically visualizing, recording, and quantitating in living systems, genetic, developmental, and physiologic changes that cannot be captured by conventional light microscopy or traditional medical imaging methods. In cellular and developmental biology, neuroscience, malignant and non-malignant human diseases, and tissue engineering, it has become increasingly clear that new approaches have to be pursued to gain insights into complex patterns of gene expression, regulation, and interaction to better understand mechanisms. Given its features (spatial, temporal and intensity range, wavelength, polarization, and coherence), light is well suited to study in vivo and in real time, complex or systemic processes that cannot be addressed in vitro. By combining molecular specificity, gene targeting, and advanced optical imaging, it has become possible to study development, gene functions, and disease processes in living animal models. In addition to real-time, tomographic 3-D fluorescence and diffuse optical imaging, techniques such as confocal and multi-photon scanning fluorescence microscopy, bioluminescence, spectral imaging and optical coherence tomography are beginning to find their way into the clinic as noninvasive diagnostic tools for early detection and improved monitoring of disease. The overall objective of the symposium is to demonstrate how newly developed modalities in optical imaging can be used to address central biological questions with high specificity and spatio-temporal resolution. Rather than focusing merely on technological issues, the symposium will present the science that motivated and benefited from a given technical advance. This tight coupling will allow the participants to fully appreciate both the costs and benefits of each approach. In addition, the symposium will bring together acknowledged leaders in the field of optical imaging with scientists and clinicians with relevant research problems in order to foster collaborations that will lead to novel interdisciplinary approaches to biological and medical questions. By reviewing exciting new developments in advanced optical imaging, the symposium will serve as a forum to demonstrate its present and future applications to important areas of science and medicine, and define future directions in these areas.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


TUESDAY, FEBRUARY 11

15:00—19:00
Registration

Rio Grande Hall D
18:15—19:15
Welcome

Bataan Hall
19:15—19:30
Orientation

Rio Grande Hall A-B
19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Rio Grande Hall A-B
Roger Y. Tsien, HHMI/University of California, San Diego, USA
Imaging Signal Transduction and Protein Sociology


WEDNESDAY, FEBRUARY 12

07:00—08:00
Breakfast

Bataan
08:00—11:00
Optical Imaging in Biology: Concepts, Goals and Approaches
Meeting has ended...abstracts no longer viewable online.

Rio Grande Hall C-D
Toshio Yanagida, Osaka University Graduate School of Frontier Biosciences, Japan
Towards Nano-Bioscience: Optical Imaging of Molecular Machines

Robert H. Singer, Albert Einstein College of Medicine, USA
Single Cell Gene Expression Profiling

David R. Walt, Tufts University, USA
High-Density Optical Fiber Arrays for Cell-Based Sensing and Cell Selection

* Thomas M. Jovin, Max-Planck Institute for Biophysical Chemistry, Germany
New FRET Modalities for Studying Protein-Protein Association and Dynamics in Cellular Signal Transduction: Homotransfer (Energy Migration) FRET (emFRET) and Photochromic FRET (pcFRET)

Sanford M. Simon, Rockefeller University, USA
Visualizing Dynamics at the Cell Surface

09:20—09:40
Coffee Break

Bataan
11:00—13:00
Poster Setup

Rio Grande Hall A-B
13:00—22:00
Poster Viewing

Rio Grande Hall A-B
16:30—17:00
Coffee & Snacks Available

Bataan
17:00—19:00
In vivo Optical Imaging for Tumor Detection and Monitoring
Meeting has ended...abstracts no longer viewable online.

Rio Grande Hall C-D
* Bruce Tromberg, University of California, Irvine, USA
Laser and Photon Propagation-Based Methods for Cancer Detection

Edward B. Brown, Massachusetts General Hospital, USA
Short Talk: Dynamic Imaging of Collagen in Tumors in vivo using Second Harmonic Generation

Tony Wyss-Coray, Stanford University School of Medicine, USA
Short Talk: Glutamate Receptor Agonist Causes Rapid Activation of a TGF-beta Reporter Gene in Brains of Transgenic Mice

19:00—20:00
Social Hour

Rio Grande Hall A-B
20:00—22:00
Poster Session 1: Optical Imaging and Studies of Neoplasia

Rio Grande Hall A-B

THURSDAY, FEBRUARY 13

07:00—08:00
Breakfast

Bataan
08:00—11:00
Optical Imaging in Stem Cell Research and Tissue Engineering
Meeting has ended...abstracts no longer viewable online.

Rio Grande Hall C-D
* David J. Mooney, Harvard University, USA
Materials to Regulate Tissue Regeneration

Johnny Huard, University of Pittsburgh, USA
Gene Therapy and Tissue Engineering Based on Muscle Derived Stem Cells: Potential for Musculoskeletal Tissue Regeneration & Repair

Michael D. Cahalan, University of California, Irvine, USA
Two-Photon Imaging of Lymphocytes in vivo

Kat Hadjantonakis, Sloan Kettering Institute, USA
Short Talk: Imaging Active Chromatin in Mouse Embryonic Stem Cells and Early Embryos

09:20—09:40
Coffee Break

Bataan
11:00—13:00
Poster Setup

Rio Grande Hall A-B
13:00—22:00
Poster Viewing

Rio Grande Hall A-B
16:30—17:00
Coffee & Snacks Available

Bataan
17:00—19:00
Optical Imaging in Gene Therapy and Regenerative Medicine
Meeting has ended...abstracts no longer viewable online.

Rio Grande Hall C-D
William F. Pralong, Swiss Federal Institute of Technology Lausanne (EPFL), Switzerland
Imaging CNS Gene Therapy

Christopher H. Contag, Institute for Quantitative Health Sciences and Engineering, USA
Optical Imaging for Visualizing Gene Expression in Living Animals

* Daniel L. Farkas, Cedars-Sinai Medical Center, USA
Optical Bioimaging for Regenerative Medicine

Yusuke Ohba, Research Institute for Microbial Diseases, Osaka University, Japan
Short Talk: Mechanism of the Spatio-Temporal Regulation of Ras and Rap1

19:00—20:00
Social Hour

Rio Grande Hall A-B
20:00—22:00
Poster Session 2: Optical Imaging in Stem Cell Research and Tissue Engineering

Rio Grande Hall A-B

FRIDAY, FEBRUARY 14

07:00—08:00
Breakfast

Bataan
08:00—11:00
Optical Imaging of Neurons: From Molecules to Circuits
Meeting has ended...abstracts no longer viewable online.

Rio Grande Hall C-D
Ehud Isacoff, University of California, Berkeley, USA
Genetically-Encoded Sensors for Optical Imaging of Electrical Activity

Timothy A. Ryan, Weill Medical College of Cornell University, USA
Dissecting Synaptic Function with Optical Methods

* Lawrence Katz, Duke University Medical Center, USA
Imaging Functional Architecture in the Mammalian Olfactory Bulb

Jeff W. Lichtman, Harvard University, USA
Monitoring Synapses in Living Animals

Romesh A. Draviam, University of Pittsburgh School of Medicine, USA
Short Talk: Analysis of Dystrophin Associated Proteins in Whole Adult Mouse Muscle Using Single Photon and Multiphoton Confocal Microscopy

09:20—09:40
Coffee Break

Bataan
11:00—13:00
Poster Setup

Rio Grande Hall A-B
13:00—22:00
Poster Viewing

Rio Grande Hall A-B
16:30—17:00
Coffee & Snacks Available

Bataan
17:00—19:00
Multimodal Imaging of Neural Development
Meeting has ended...abstracts no longer viewable online.

Rio Grande Hall C-D
Amiram Grinvald, Optical Imaging Ltd., Israel
Visualization of Cortical Dynamics

* Scott E. Fraser, University of Southern California, USA
Multi-Photon, Multispectral-Spectral Imaging of Neural Development

Arthur W. Toga, University of California, Los Angeles, USA
Multidimensional Brain Image Database

Yukihiro Hirose, Kyoto University, Japan
Short Talk: Single Cell Fate Analysis in Early Neural Development of Medaka and its Presentation using 3-D Computer Graphics

19:00—20:00
Social Hour

Rio Grande Hall A-B
20:00—22:00
Poster Session 3: Optical Imaging in Neurobiology

Rio Grande Hall A-B

SATURDAY, FEBRUARY 15

07:00—08:00
Breakfast

Bataan
08:00—11:00
Optical Imaging of Angiogenesis and Microcirculation
Meeting has ended...abstracts no longer viewable online.

Rio Grande Hall C-D
* Dorothea Becker, University of Pittsburgh, USA
Spectral and Fluorescence Imaging of Melanoma and Angiogenesis

Rox Anderson, Massachusetts General Hospital, USA
Confocal and Vital Microscopy of Skin

Elizabeth A.V. Jones, McGill University, Canada
Short Talk: In vivo Imaging and Quantification of Microvascular Blood Flow during Mammalian Development

Thomas M. Jovin, Max-Planck Institute for Biophysical Chemistry, Germany
and

Sanford M. Simon, Rockefeller University, USA
Short Talk: Quantum Dots

09:20—09:40
Coffee Break

Bataan
16:30—17:00
Coffee & Snacks Available

Bataan
17:00—19:00
Emerging Methodologies of Optical Bioimaging and Intervention
Meeting has ended...abstracts no longer viewable online.

Rio Grande Hall C-D
* Martin Chalfie, Columbia University, USA
GFP: Shedding Light on Biological Processes

Warren S. Grundfest, University of California, Los Angeles, USA
Time-Resolved Fluorescence Spectroscopy for the Detection of Unstable Atherosclerotic Lesions

James G. Fujimoto, Massachusetts Institute of Technology, USA
Optical Coherence Tomography Imaging for in vivo Imaging

Stefanie J. Mandl, BN-Immunotherapeutics, USA
Short Talk: Non-Invasive Assessment of the Degree of Apoptosis and Tumor Cell Loss Observed by 99mTc-Annexin V Micro Single Photon Emission Computed Tomography (mSPECT) and in vivo Bioluminescent Imaging (BLI) Following a Single Dose of Chemotherapy

19:00—20:00
Social Hour

Bataan
20:00—23:00
Entertainment

Bataan

SUNDAY, FEBRUARY 16

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge additional support for this conference from:


Carl Zeiss MicroImaging, Inc.


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