Beaver Run Resort Floorplan

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This meeting took place in 2005



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Axonal Connections: Molecular Cues for Development and Regeneration (C6)


Organizer(s) Stephen M. Strittmatter, Marc Tessier-Lavigne and John G. Flanagan
March 31—April 4, 2005
Beaver Run Resort • Breckenridge, Colorado USA
Abstract Deadline: Nov 30, 2004
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Jan 31, 2005

Supported by The Director's Fund

Summary of Meeting:
The functioning of the nervous system depends on its complex pattern of connections. Axonal connections are initially set up during development by cues, which guide axons along specific pathways, and then specify connection sites within the target region. In recent years, dramatic progress has been made in identifying such cues molecularly. Based on this progress, current studies are elucidating the molecular logic of extracellular signals that set up connectivity, as well as intracellular pathways that interpret these signals. In the adult central nervous system, damaged axonal connections do not regenerate, even though peripheral nerves can regenerate efficiently. This is due at least in part to CNS inhibitors, some of which have now been cloned. This meeting will bring together the fields of development and regeneration, with the goal of facilitating synergistic overlaps in techniques, molecules and biology. Topics will include basic research on molecular cues, and resulting new approaches toward therapeutic axon repair.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


THURSDAY, MARCH 31

15:00—19:30
Registration

Foyer
18:30—19:30
Refreshments

Foyer
19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Peaks 4-5
Marc Tessier-Lavigne, Stanford University, USA
Molecular Mechanisms of Axon Growth, Guidance and Regeneration


FRIDAY, APRIL 1

07:00—08:00
Breakfast

Peaks 6-12
08:00—11:00
Pathway Selection and Choice Points
Meeting has ended...abstracts no longer viewable online.

Peaks 4-5
* Marc Tessier-Lavigne, Stanford University, USA

Christine E. Holt, University of Cambridge, UK
Directional Guidance and Local Translation in Retinal Growth Cones

Carol Ann Mason, Columbia University, USA
Genes that Pattern the Retina and Diencephalon during Optic Chiasm Formation

Oliver Hobert, Columbia University, USA
Sugar Coding the Nervous System: The Role of Secondary Modifications of Proteoglycans in Axon Guidance Choices

Till Marquardt, The Salk Institute for Biological Studies, USA
Short Talk: Eph-Ephrin Mediated Signaling Mechanisms Directing Spinal Motor Axon Targeting

Yimin Zou, University of California, San Diego, USA
Short Talk: A Diffusible Guidance cue, Wnt3, is a Candidate Opposing Signal for Medial-Lateral Retinotectal Mapping

09:20—09:40
Coffee Break

Foyer
11:00—13:00
Poster Setup

Peaks 1-3
13:00—22:00
Poster Viewing

Peaks 1-3
16:30—17:00
Coffee & Snacks Available

Foyer
16:45—19:00
Target Recognition
Meeting has ended...abstracts no longer viewable online.

Peaks 4-5
* Rüdiger Klein, Max Planck Institute of Neurobiology, Germany

Azad Bonni, Harvard Medical School, USA
Cdh1-APC Control of Axonal Growth and Patterning in the Mammalian Brain

Hollis T. Cline, The Scripps Research Institute, USA
Regulation of Terminal Branching

Joshua R. Sanes, Harvard University, USA
Synapse Formation: Coordinating Pre- And Postsynaptic Differentiation

Karel Svoboda, Janelia Research Campus & Cold Spring Harbor Laboratory, USA
Experience-Dependent Structural Plasticity in the Adult Neocortex in vivo

19:00—20:00
Social Hour

Peaks 1-3
19:30—22:00
Poster Session 1

Peaks 1-3

SATURDAY, APRIL 2

07:00—08:00
Breakfast

Peaks 6-12
08:00—11:15
Inhibitors of Regeneration
Meeting has ended...abstracts no longer viewable online.

Peaks 4-5
* Marc Tessier-Lavigne, Stanford University, USA

Stephen B. McMahon, King's College London, UK
Proteoglycans, plasticity and spinal cord repair

Martin E. Schwab, University of Zürich, Switzerland
Nogo-A, a regulator of regeneration, neurite growth and circuit stability

Marie T. Filbin, Hunter College, USA
Myelin Inhibitors of Regeneration: How They Work and How to Overcome Them.

Stephen M. Strittmatter, Yale University, USA
Nogo and NgR in Adult CNS Axonal Regeneration and Plasticity

Karthik Venkatesh, University of Rochester School of Medicine and Dentistry, USA
Short Talk: NgR2 is a Novel MAG Receptor: Insights into the Structural Basis of Receptor Function and Specificity

09:20—09:40
Coffee Break

Foyer
11:00—13:00
Poster Setup

Peaks 1-3
13:00—22:00
Poster Viewing

Peaks 1-3
16:30—17:00
Coffee & Snacks Available

Foyer
16:45—19:00
Extracellular Signals Regulating Axonal Growth
Meeting has ended...abstracts no longer viewable online.

Peaks 4-5
* Joshua R. Sanes, Harvard University, USA

M. Douglas Benson, University of Texas Southwestern Medical Center, USA
Short Talk: Ephrin-B3 is a Myelin-Based Inhibitor of Neurite Outgrowth

Rüdiger Klein, Max Planck Institute of Neurobiology, Germany
Ephrins and Eph Receptors in Neural Development

David L. Van Vactor, Harvard Medical School, USA
Syndecan Promotes Synapse Growth Through Interactions with the Receptor Phosphatase LAR.

Alex L. Kolodkin, Johns Hopkins University School of Medicine, USA
Semaphorin Function in Drosophila and Vertebrates

19:00—20:00
Social Hour

Peaks 1-3
19:30—22:00
Poster Session 2

Peaks 1-3

SUNDAY, APRIL 3

07:00—08:00
Breakfast

Peaks 6-12
08:00—11:00
Pathways Downstream of Axonal Receptors
Meeting has ended...abstracts no longer viewable online.

Peaks 4-5
* Stephen M. Strittmatter, Yale University, USA

Yuh-Nung Jan, University of California, San Francisco, USA
Comparison of Axon and Dendrite Patterning and Remodeling

Michael E. Greenberg, Harvard Medical School, USA
Distinct roles for Dbl family GEFs in ephrin-mediated growth cone repulsion

Mu-ming Poo, Institute of Neuroscience, CAS, China
Ca2+ Signaling in Growth Cone Guidance and Directed Neuronal Migration

Zhigang He, Children's Hospital, Boston, USA
Mechanisms of CNS Growth Inhibition by Myelin Inhibitors

Katharine J.M. Marler, King's College London, UK
Short Talk: Neurite Repulsion by Chondroitin Sulphate Proteoglycan or Tenascin Requires PAK

09:20—09:40
Coffee Break

Foyer
16:30—17:00
Coffee & Snacks Available

Foyer
16:45—19:00
Signals in Degeneration and Regeneration
Meeting has ended...abstracts no longer viewable online.

Peaks 4-5
* Michael E. Greenberg, Harvard Medical School, USA

Liqun Luo, Stanford University, USA
Developmental Axon Pruning through Axon Degeneration

Ben A. Barres, Stanford University, USA
Why is Wallerian Degeneration so Slow in the CNS?

Clifford J. Woolf, Children's Hospital, USA
Master switches that determine intrinsic growth in adult neurons

19:00—20:00
Social Hour

Peaks 1-3
20:00—23:00
Entertainment

Peaks 1-3

MONDAY, APRIL 4

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge additional support for this conference from:

March of Dimes Foundation National Multiple Sclerosis Society

Biogen Idec
 

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Genentech, Inc.


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


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If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

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If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676