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This meeting took place in 2006
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Epigenetics and Chromatin Remodeling in Development (A7)
Organizer(s) Renato Paro and Peter Fraser
January 19—24, 2006
Keystone Resort • Keystone, Colorado USA
Abstract Deadline: Sep 19, 2005
Late Abstract Deadline: Oct 12, 2005
Scholarship Deadline: Sep 19, 2005
Early Registration Deadline: Nov 18, 2005
Supported by The Director's Fund
Summary of Meeting:
The stability of gene expression patterns, which define different cellular states, is highly dependent on chromatin structure and function. Regulatory features invoked by, for example, particular histone modifications or nuclear architecture greatly influence the way genetic information is interpreted during developmental processes. Such an epigenetic constitution of the nucleus is heritable, providing the basis for mechanisms like the permanent inactivation of an X chromosome or genomic imprinting in mammalian cells. The recent identification of many components of epigenetic regulation has created enormous excitement in the field, not only because we foresee a better understanding of the basic mechanisms on how developmental decisions are maintained, but also because we might learn how aberrant cases, like cancer cells, change their epigenetic hallmarks. Epigenetic gene control also needs to be considered to better understand and approach more applied topics like nuclear cloning, stem cells and tissue engineering. This meeting will bring together scientists who have identified epigenetic constituents and studied their regulatory contributions at the molecular level, with scientists who study, in more complex organisms, epigenetic programming of cellular fates during normal developmental and in the disease case.
View Scholarships/Awards
The stability of gene expression patterns, which define different cellular states, is highly dependent on chromatin structure and function. Regulatory features invoked by, for example, particular histone modifications or nuclear architecture greatly influence the way genetic information is interpreted during developmental processes. Such an epigenetic constitution of the nucleus is heritable, providing the basis for mechanisms like the permanent inactivation of an X chromosome or genomic imprinting in mammalian cells. The recent identification of many components of epigenetic regulation has created enormous excitement in the field, not only because we foresee a better understanding of the basic mechanisms on how developmental decisions are maintained, but also because we might learn how aberrant cases, like cancer cells, change their epigenetic hallmarks. Epigenetic gene control also needs to be considered to better understand and approach more applied topics like nuclear cloning, stem cells and tissue engineering. This meeting will bring together scientists who have identified epigenetic constituents and studied their regulatory contributions at the molecular level, with scientists who study, in more complex organisms, epigenetic programming of cellular fates during normal developmental and in the disease case.
View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference
THURSDAY, JANUARY 19
FRIDAY, JANUARY 20
SATURDAY, JANUARY 21
SUNDAY, JANUARY 22
MONDAY, JANUARY 23
TUESDAY, JANUARY 24
Conference Program Print | View meeting in 12 hr (am/pm) time
THURSDAY, JANUARY 19
19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.
Azim Surani,
University of Cambridge, UK
Epigenetic Programming of the Genome in the Embryo and Germ Cells
Epigenetic Programming of the Genome in the Embryo and Germ Cells
08:00—11:15
Chromatin Structure and Function
Meeting has ended...abstracts no longer viewable online.
C. David Allis,
Rockefeller University, USA
Beyond the Double Helix: Reading and Writing the 'Histone Code'
Beyond the Double Helix: Reading and Writing the 'Histone Code'
*
Peter B. Becker,
University of Munich, Germany
Site-Specific Acetylation Defines an Embryonic form of ISWI Associated with Mitotic Chromatin
Site-Specific Acetylation Defines an Embryonic form of ISWI Associated with Mitotic Chromatin
Zhiguo Zhang,
Mayo Clinic, USA
Short Talk: Rtt106p is a Novel Histone Chaperone Involved in Epigenetic Silencing
Short Talk: Rtt106p is a Novel Histone Chaperone Involved in Epigenetic Silencing
Stefan Kubicek,
Austrian Academy of Sciences, Austria
Epigenetic Control by Histone Methylation
Epigenetic Control by Histone Methylation
Robert A. Martienssen,
Cold Spring Harbor Laboratory, USA
Regulation of Histone Methylation Patterns by RNAi in Plants and Fission Yeast
Regulation of Histone Methylation Patterns by RNAi in Plants and Fission Yeast
Kevin V. Morris,
Center for Gene Therapy, City of Hope, USA
Short Talk: The Antisense Strand of Small Interfering RNAs Directs Histone Methylation and Transcriptional Gene Silencing in Human Cells
Short Talk: The Antisense Strand of Small Interfering RNAs Directs Histone Methylation and Transcriptional Gene Silencing in Human Cells
17:00—19:00
Establishing Epigenetic Marks
Meeting has ended...abstracts no longer viewable online.
*
Steven Henikoff,
Fred Hutchinson Cancer Research Center, USA
Epigenetic Patterns Generated by Assembly of Histone Variants into Nucleosomes
Epigenetic Patterns Generated by Assembly of Histone Variants into Nucleosomes
Caline Karam,
Columbia University Medical Center, USA
Short Talk: The Role of JIL-1 Mediated Histone H3 Phosphorylation in Transcriptional Activation
Short Talk: The Role of JIL-1 Mediated Histone H3 Phosphorylation in Transcriptional Activation
En Li,
China Novartis Institutes for BioMedical Research, China
Role of DNA Methyltransferases in Mammalian Development
Role of DNA Methyltransferases in Mammalian Development
Terumi Kohwi-Shigematsu,
Lawrence Berkeley National Laboratory, USA
A New Role of Genome Organizer SATB1 in Breast Cancer Mestastasis
A New Role of Genome Organizer SATB1 in Breast Cancer Mestastasis
08:00—11:15
Chromatin-Controlled Gene Regulation in Development
Meeting has ended...abstracts no longer viewable online.
*
Vicki L. Chandler,
Minerva Schools at Keck Graduate Institute, USA
Heritable Chromatin Structures are Established through Trans-Interactions between Tandem Repeats
Heritable Chromatin Structures are Established through Trans-Interactions between Tandem Repeats
Jeannie T. Lee,
Massachusetts General Hospital, USA
Cis-Regulatory Chromatin Dynamics at the X-Inactivation Center
Cis-Regulatory Chromatin Dynamics at the X-Inactivation Center
Dominic John Ciavatta,
University of North Carolina at Chapel Hill, USA
Short Talk: DNA Insulators Prevent Repression of a Targeted X-linked Transgene but not Its Random or Imprinted X-Inactivation
Short Talk: DNA Insulators Prevent Repression of a Targeted X-linked Transgene but not Its Random or Imprinted X-Inactivation
Kami Ahmad,
Harvard Medical School, USA
Replication-Independent Histone Replacement, Histone Variants and Maintaining Epogenetic States
Replication-Independent Histone Replacement, Histone Variants and Maintaining Epogenetic States
Laurie Jackson-Grusby,
Harvard Medical School, USA
Reprogramming Epigenetic Imprinting
Reprogramming Epigenetic Imprinting
Nora I. Engel,
Temple University School of Medicine, USA
Insulators, Mathylation and Transcriptional Regulation: Complesities of Imprinting Control
Insulators, Mathylation and Transcriptional Regulation: Complesities of Imprinting Control
17:00—19:00
Nuclear Positioning
Meeting has ended...abstracts no longer viewable online.
Giacomo Cavalli,
Institute of Human Genetics, France
Association of Polycomb Group Response Elements in the Nuclear Space
Association of Polycomb Group Response Elements in the Nuclear Space
Wendy A. Bickmore,
University of Edinburgh, UK
Nuclear Re-Organization during Embryonic Development
Nuclear Re-Organization during Embryonic Development
Daryl Gohl,
Princeton University, USA
Short Talk: Analyzing Boundary Element Pairing and Competiton
Short Talk: Analyzing Boundary Element Pairing and Competiton
08:00—11:15
Mechanisms of Cellular Memory
Meeting has ended...abstracts no longer viewable online.
Renato Paro,
ETH Zurich, Switzerland
Epigenetic Control of Tissue Regeneration in Drosophila
Epigenetic Control of Tissue Regeneration in Drosophila
Maxim Nekrasov,
Australian National University, Australia
Short Talk: Characterization of the Drosophila PRC2 HMTase
Short Talk: Characterization of the Drosophila PRC2 HMTase
Alexander Tarakhovsky,
Rockefeller University, USA
Protein Lysine Methylation and Signal Transduction
Protein Lysine Methylation and Signal Transduction
Keji Zhao,
NHLBI, National Institutes of Health, USA
Short Talk: Identification and Characterization of Human Polycomb Response Elements
Short Talk: Identification and Characterization of Human Polycomb Response Elements
*
Ueli Grossniklaus,
University of Zürich, Switzerland
Epigenetic Inheritance during Arabidopsis Seed Development
Epigenetic Inheritance during Arabidopsis Seed Development
Peter Verrijzer,
Erasmus University Medical Center, Netherlands
PREs are CIS-Regulatory Elements That Mediate Function of PcG and TRXG Proteins
PREs are CIS-Regulatory Elements That Mediate Function of PcG and TRXG Proteins
17:00—19:00
Cellular Plasticity and Tissue Reprogramming
Meeting has ended...abstracts no longer viewable online.
*
Eric N. Olson,
University of Texas Southwestern Medical Center, USA
Signfalling to the Genome: Lessons from the Heart
Signfalling to the Genome: Lessons from the Heart
Meinrad Busslinger,
Research Institute of Molecular Pathology, Austria
Transcriptional Control of B Cell Identity by Pax5
Transcriptional Control of B Cell Identity by Pax5
Jiang Wu,
University of Texas Southwestern Medical Center, USA
Short Talk: An Essential Epigenetic Switch for Progenitor-to-Post-Mitotic Neural Development
Short Talk: An Essential Epigenetic Switch for Progenitor-to-Post-Mitotic Neural Development
Rudolf Jaenisch,
Whitehead Institute for Biomedical Research, USA
Molecular Control of Pluripotency and Self-Renewal
Molecular Control of Pluripotency and Self-Renewal
08:00—11:15
Cancer Epigenetics
Meeting has ended...abstracts no longer viewable online.
*
Peter A. Jones,
Van Andel Research Institute, USA
DNA Footprinting of CpG Islands at Single Molecule Resolution
DNA Footprinting of CpG Islands at Single Molecule Resolution
Tom Latham,
Westerb General Hospital, UK
Short Talk: Transgenic Mice Overexpressing DNA Methyltransferase Dnmt3b Develop Abnormal Cpg Island Methylation and Increased Progression of Apc min Intestinal Tumours
Short Talk: Transgenic Mice Overexpressing DNA Methyltransferase Dnmt3b Develop Abnormal Cpg Island Methylation and Increased Progression of Apc min Intestinal Tumours
Stephen B. Baylin,
Johns Hopkins University School of Medicine, USA
Epigenetic Control of Cancer or Questions of Epigenetic Networks Gone Wrong
Epigenetic Control of Cancer or Questions of Epigenetic Networks Gone Wrong
Michael J. Boland,
University of Nebraska Medical Center, USA
Short Talk: Initial Characterization of an Interaction between C5-DNA Methyltransferase, Dnmt3b, and Thymine DNA Glycosylase
Short Talk: Initial Characterization of an Interaction between C5-DNA Methyltransferase, Dnmt3b, and Thymine DNA Glycosylase
Maarten Van Lohuizen,
Netherlands Cancer Institute, Netherlands
Polycomb Repressors Controlling Stem Cell Fate: Implications for Cancer and Development
Polycomb Repressors Controlling Stem Cell Fate: Implications for Cancer and Development
Trang Hoang,
Université de Montréal, Canada
Integration of Proliferative Signals from EED and BMI1 Proteins
Integration of Proliferative Signals from EED and BMI1 Proteins
17:00—19:00
Stem Cell Programming
Meeting has ended...abstracts no longer viewable online.
Allan C. Spradling,
HHMI/Carnegie Institute, USA
The Lighten-up/p68 RNA Helicase Regulates Transcriptional Deactivation by Promoting RNA Release from Chromatin
The Lighten-up/p68 RNA Helicase Regulates Transcriptional Deactivation by Promoting RNA Release from Chromatin
*
Emma Whitelaw,
Queensland Institute of Medical Research, Australia
An ENU Screen for Modifiers of Epigenetic Gene Silencing in the Mouse
An ENU Screen for Modifiers of Epigenetic Gene Silencing in the Mouse
David J. Katz,
Emory University, USA
Short Talk: Histone H3 Lysine 4 Methylation Guards the Germ Cell Lineage
Short Talk: Histone H3 Lysine 4 Methylation Guards the Germ Cell Lineage
Wolf Reik,
Babraham Institute, UK
Imprinting and Epigenetic Reprogramming in Mammalian Development
Imprinting and Epigenetic Reprogramming in Mammalian Development
*Session Chair †Invited, not yet responded.
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