Whistler Conference Centre Floorplan

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This meeting will be conducted in English.
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Twitter hashtag for this meeting: #KSlncRNA
Long Noncoding RNAs: From Molecular Mechanism to Functional Genetics (X2)
joint with the meeting on RNA-Protein Interactions (X1)Scientific Organizers: Saba Valadkhan and Piero Carninci
February 24—28, 2019
Whistler Conference Centre, Whistler, British Columbia, Canada
Sponsored by Cell Research and Ionis Pharmaceuticals, Inc.
Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested.
Keystone Symposia is committed to maintaining a positive and respectful environment at its meetings. To this end, please review and comply with our policies.
DEADLINES:
*All deadlines end at 11:59 PM US Mountain Standard Time
Scholarship Deadline: Oct 25, 2018 [details]
Discounted Abstract Deadline: Oct 25, 2018 [details]
Abstract Deadline: Nov 29, 2018 [details]
Discounted Registration Deadline: Jan 10, 2019 [details]
If you have missed a deadline due to the US government shutdown, please contact our office.
Click here to view Cancellation Policy
Discounted Abstract Deadline: October 25, 2018
*All deadlines end at 11:59 PM US Mountain Standard TimeAbstract Submission Fee: 100.00 USD*
Submission by this date receives 50.00 USD discount.
*50.00 USD will be applied to Registration Fee when you register
Abstract Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadlines. Submitting an abstract does not constitute or guarantee registration.
Submitting your abstract early allows us to:
- submit your abstract to organizers to be considered for a short talk
- accept your abstract online
- include your abstract on our website and in our secure mobile app
- reserve your space at the meeting for a poster presentation.**
(The Abstract Deadline: is November 29, 2018)
Global Health Travel Award Deadline:
*All deadlines end at 11:59 PM US Mountain Standard Time
Global Health Travel Award Details:
You MUST complete your Global Health Travel Award appplication by the Global Health Travel Award Deadline
and complete the other required steps (verify your contact information and submit a recommendation letter)
to be considered for a travel award.
Click here to learn more about Global Health Travel Awards.
Scholarship Deadline: October 25, 2018
*All deadlines end at 11:59 PM US Mountain Standard Time
Scholarship Details:
You MUST submit your abstract by the Scholarship Deadline and complete the other required steps (submit a scholarship application and submit a mentor letter) to be considered for a scholarship.
Abstract Deadline: November 29, 2018
*All deadlines end at 11:59 PM US Mountain Standard Time
Abstract Submission Fee: 100.00 USD*
*50.00 USD will be applied to Registration Fee when you register
Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadline. Submitting an abstract does not constitute or guarantee registration.
Submitting your abstract by the Abstract Deadline allows us to:
- submit your abstract to organizers to be considered for a short talk
- include your abstract on our website and in our secure mobile app
- reserve your space at the meeting for a poster presentation.**
Abstracts submitted after the Abstract Deadline will NOT be considered for a short talk.
(Discounted Abstract Deadline: is October 25, 2018)
Discounted Registration Deadline: January 10, 2019
*All deadlines end at 11:59 PM US Mountain Standard Time
Registration Fee: 945.00 USD* (includes 200.00 USD discount)
Student Registration Fee: 720.00 USD* (must complete student verification form)
*Includes 50.00 USD of your abstract submission fee
After the Discounted Registration Deadline:
Registration Fee: 1145.00 USD*
Student Registration Fee: 920.00 USD* (must complete student verification form)
*Includes 50.00 USD of your abstract submission fee
Registration spaces are limited and may fill prior to discounted registration deadline.
We highly recommend that you not make a reservation with these companies or any other housing service! These companies' representations to participants have been misleading. Please report any calls or correspondence you might have received to Keystone Symposia and book only through lodging links in your Keystone Symposia account, an established travel agency or directly with the hotel(s) listed on our website.
Conference Program Print | View meeting in 12 hr (am/pm) time
The meeting will begin on Sunday, February 24 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, February 28 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, March 1 in order to fully experience the meeting.
SUNDAY, FEBRUARY 24
New Genome Editors and Inhibitors from the CRISPR Family Tree
Registered attendees can view abstracts starting on 01/24/2019
Broad Roles of RNA-Binding Proteins in Regulated Gene Expression
RNA-Protein Interactions Regulate Epigenetic Silencing
Patterns in the Recognition of RNAs by RBPs
Short Talk: Proteome-Wide and Quantitative Identification of RNA-Dependent Protein Complexes
Short Talk: Dissecting the Characteristics and Functions of Transcribed Enhancers
Short Talk: Elucidating the Crosstalk between hnRNPK Binding and Nuclear Retention of Long RNAs
Short Talk: Characteristic Convergent Variation in LINE-1 Nucleotides Can Benefit Redundantly Forming Triplexes with lncRNA in Mammalian X-Chromosome Inactivation
A Long Noncoding RNA Attenuates Dendritic Cell Function and Decreases Autoimmune Disease Susceptibility
Long Non-Coding RNA-26 Promotes Intracellular Mycobacterium tuberculosis Growth through Inhibition of Pro-Inflammatory Genes Expression and Macrophage Activation
Charme Long Noncoding RNA Shapes the 3D Nuclear Structure by its Close Cooperation with Chromatin
Functional Characterization of Hypoxia-Regulated lncRNAs in Non-Small Cell Lung Carcinomas
Regulation of Diacyl Glycerol-Mediated Protein Kinase C-Beta Activation by Vascular Endothelial -Associated Long Noncoding RNA 2 Modulates Endothelial Permeability
SAMMSON Fosters Cancer Cell Fitness by Concertedly Enhancing Mitochondrial and Cytosolic Translation
The Age and Shear Regulated Long Non-Coding RNA Aerrie Controls Endothelial Cell Function
The Shear Stress-Induced Long Non-Coding RNA LASSIE as a Regulator of Endothelial Cell Junctions
Proximity-CLIP Provides a Snapshot of Protein-Occupied RNA Elements in Sub-Cellular Compartments
Systematic Discovery of Endogenous Human Ribonucleoprotein Complexes
An Integrated High-Throughput Chemical Screening Platform for RNA Splicing Modulators
Utilization of a Novel Technique to Identify RNA-Binding Proteins
Protein Half-Lives on RNA Reveal Human Ribosome Maintenance Independent of Ribosome Biogenesis
Probing Ribosome Assembly Dynamics with CLASH
Systematic Identification and Quantitative Measurement of RNA-Protein Interactions by incPRINT
Registered attendees can view abstracts starting on 01/24/2019
Functions, Modes of Action and Localization of Long Noncoding RNAs in Mammalian Cells
Role of Retrotransposon Elements within Cellular RNAs
Defining the Landscape of Covalent Modifications in Conserved Noncoding RNAs using Direct-RNA Sequencing
Short Talk: LEADeR Role of miR-205 Host Gene as Long Non-Coding RNA in Prostate Basal Cell Differentiation
Short Talk: Somatic Retrotransoposons-Associated Structural Variants in Health and Neurodegeneration
A New Mode of Xist Action
RNP Granules in Health and Disease
Large RNP Transport Granules Drive mRNA Localization
Short Talk: Pat1 Activates Late Steps in mRNA Decay by Multiple Mechanisms
Short Talk: RNAPII Condensates Connect Genome Organization and Gene Regulation
Registered attendees can view abstracts starting on 01/24/2019
RNAi in Chromatin Remodeling
Protein-RNA-Chromatin Interactions
Xist RNA Antagonizes the Chromatin Remodeler, BRG1, on the Inactive X Chromosome
RNAi Component Ago1 Interacts with lncRNAs to Regulate Nuclear Architecture and Cell Differentiation
Short Talk: DNA-PK Leverages Non-Coding RNA Binding to Regulate Nucleolar Functions
Short Talk: Arginine Methylation of RNA Binding Protein TLS Inhibits Binding to Long Noncoding RNA, Repressing the Histone Acetyltransferase Activity
Short Talk: The DNMT1-Associated lincRNA DACOR1 Reprograms Genome-Wide DNA Methylation in Colon Cancer
Short Talk: NESPR Long Non-Coding RNA, a New Neuroblastoma-Specific Oncogene
Registered attendees can view abstracts starting on 01/24/2019
Regulation of Cellular Quiescence by lncRNAs
lncRNAs in Mammalian Physiology and Disease
Genetic Models Reveal cis and trans Immune-Regulatory Activities for lincRNA-Cox2
Short Talk: Novel Tuna Isoforms Define the Pluripotent Stem Cell State
Short Talk: The Long Noncoding RNA Landscape of Neuroendocrine Prostate Cancer and its Clinical Implications
Target-Directed miRNA Decay: Yet Another Function of Ago Proteins
CELF2 Regulation of Splicing and Polyadenylation in Activated T Cells
Short Talk: RNA-Protein Complex Formation in a Mysterious Large ncRNA
Short Talk: Decipering the Splicing Code of Coordinated RN- Binding Proteins PSI and hrp48 in Sculpting the Drosophila Transcriptome
Registered attendees can view abstracts starting on 01/24/2019
Spatial Transcriptome Analysis and Disease
Different Mechanisms Define lncRNA and Protein Coding Gene Transcription Units in Mammalian Cells
Systematic Discovery of Novel Peptides from the Noncanonical Translation of Non-Coding Regions
Short Talk: Functional Prediction and Validation of lncRNAs using Allele-Sensitive Single-Cell RNA-Sequencing
Short Talk: Novel High-Throughput Tools for in vivo Functional Characterization of Regulatory RNAs
Short Talk: Circular RNA Mediate IBD Genetic Risk
Motor-Mediated RNA Transport and Localization
Neuronal Targets for RNA Binding Proteins
Molecular Architecture and Dynamics of mRNA Transport Complexes
Short Talk: Exploring the Characteristics and Functions of RNA Secondary Structures Bound in vivo by Staufen
Short Talk: NRDE2 Negatively Regulates Nuclear Exosome Functions and Controls Embryonic Stem Cell Self-Renewal
Short Talk: The Perlman Syndrome Dis3l2 Exonuclease as Guardian of ER-associated Translation
Short Talk: Complementary 3’UTRs Derived from Overlapping Genes can Promote Cytoplasmic Co-Localization of Distinct mRNAs
Short Talk: Transcriptional Control of Neuronal Differentiation by an RNA-Binding Protein
Registered attendees can view abstracts starting on 01/24/2019
Genome Regulation by Long Noncoding RNAs
eRNAs Mediate Phase Separation of Ligand-Activated Enhancers to License Cooperative Chromosomal Enhancer Assembly
The Firre Locus Produces a Trans-Acting RNA Molecule that Functions in Hematopoiesis
Short Talk: lncRNA DIGIT and BRD3 Protein Form Phase-Separated Condensates and Regulate Endoderm Differentiation.
Short Talk: Intergenic Non-Coding RNA-DNA Hybrids Maintain Nucleolar Biomolecular Condensates and Ribosome Biogenesis
Splicing Activation by Rbfox Requires Self-Aggregation of its Tyrosine-Rich Domain
Interaction of U1snRNP with Drugs and RNA-Binding Proteins in Splicing Regulation
Collaborative RNA Recognition Specificity by PUF Proteins
Short Talk: The Individual Contributions of Single IMP3 RNA-Binding Domains to the Recognition of Clustered Sequences in Target mRNAs
Short Talk: Structural Insights into MLE-Unr-roX2 Complex Assembly during Early Steps of Drosophila Dosage Compensation
Registered attendees can view abstracts starting on 01/24/2019
Two-Dimensional and Three-Dimensional Structure-Function Relationships for Individual Long Noncoding RNAs
lncRNAs of Novel Origin
Short Talk: A ncRNA Derived from xbp-1 mRNA Cleavage Promotes Axon Regeneration
Short Talk: Circular RNAs Expressed from the BRCA1 Pseudogene Regulates Antiviral Immune Signaling in Breast Cancer Cells
Short Talk: Nucleolus-Enriched Repeat-Containing Noncoding RNA Regulates rDNA Transcription.
Short Talk: SHAPE-MaP Identifies Two Structural Modules with Distinct Function in the lncRNA Growth Arrest Specific 5 (Gas5)
Short Talk: Inhibition of Novel Long Noncoding RNA lncExACT1 Induces Physiological Cardiac Hypertrophy
Short Talk: The lncRNA HERVH Negatively Regulates Chromatin Targeting and Remodeling Mediated by CHD7
The Barricade Complex as A Rate-Limiting Blockade against mRNA Deadenylation
Structure and Function of the Spliceosome
CRISPR-Cas Mediated Cleavage of Invading RNAs
Enhancing Genome Editing with New Cas9s and Fully Stabilized Guides
Short Talk: MyoD-Induced Enhancer RNA Interacts with hnRNPL Protein via CAAA Motif to Activate Target Gene Transcription during Myogenic Differentiation
Short Talk: Structural and Functional Dissection of Eukaryotic snoRNP Complexes Catalyzing rRNA 2'-O-Ribose Methylations
Short Talk: A Novel Plant-Specific Structural Element within the Arabidopsis Telomerase RNA
The Tug1 lncRNA Locus Is Essential for Male Fertility and Harbors a Tripartite DNA, lncRNA and Protein Functionality
Point Centromere Activity Requires an Optimal Level of Centromeric Non-Coding RNA
En Bloc and Segmental Deletions of Human XIST Reveal X Chromosome Inactivation-Involving RNA Elements
Investigating the Role of a Synaptically Targeted Intronic lncRNA in Memory Storage
Regulation of Neuroregeneration by Long Noncoding RNAs
B2M RNA Facilitates HSV-1 Gene Expression via Interacting with ASH2L and VP16
Unraveling the Biogenesis and Function of the Circular RNA ciRS-7
Investigating RNA Pseudouridylation Patterns in Viral Infection
hnRNP K Overexpression Drives Myeloid Malignancy via Interaction with RUNX1
Adenovirus Co-Opts Cellular m6A Modification Machinery to Facilitate Viral RNA Splicing and Protein Production
RNA Modifications and Regulation of Gene Expression
Temporal Control of ESRP2 Licenses Fetal-to-Adult Switch in Alternative Splicing Required for Hepatocyte Maturation
hnRNP L-Dependent Protection of Normal mRNAs from NMD Subverts Quality Control in B Cell Lymphoma
Study of FUS-Dependent circRNAs Function and Localization in Murine Motor Neurons
SRSF3 Promotes Glioblastoma Progression Via Splicing Regulation of Alternative Exons
Sequence-Specific Inhibition of Noncoding RNA Generated at Dysfunctional Telomeres Improves Progeric Phenotypes and Extends Lifespan in two Animal Species
A Novel Function of MIWI/piRNA in Activating Translation of Spermiogenic mRNAs during Spermiogenesis
Targeting RNA with Antisense Oligonucleotides to Treat Disease
Registered attendees can view abstracts starting on 01/24/2019
We gratefully acknowledge support for this conference from:
Keystone Symposia thanks our Sponsors for generously supporting this meeting:
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We gratefully acknowledge the generous grant for this conference provided by:
We gratefully acknowledge additional support for this conference from:
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We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:
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If your organization is interested in joining these entities in support of Keystone
Symposia, please contact: Sarah Lavicka,
Director of Development, Email: sarahl@keystonesymposia.org, Phone:+1 970-262-2690 Click here for more information on Industry Support and Recognition Opportunities. If you are interested in becoming an advertising/marketing in-kind partner, please contact: Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org, Phone:+1 970-262-2676 |