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Monday, January 27 | 4:00PM - 8:00PM
Arrival and Registration
Room: Sweeney Ballroom Foyer


Monday, January 27 | 6:00PM - 8:00PM
Welcome Mixer
Room: Sweeney F
No registration fees are used to fund alcohol served at this function.

Tuesday, January 28 | 7:00AM - 8:00AM
Breakfast
Room: Sweeney F


Tuesday, January 28 | 7:30AM - 8:00AM
Poster Setup
Room: Sweeney F


Tuesday, January 28 | 8:00AM - 7:00PM
Poster Viewing
Room: Sweeney F


Tuesday, January 28 | 8:00AM - 9:00AM
Welcome and Keynote Address (Joint)
Room: Sweeney Ballroom A-E

Speaker 1 of 3
* Patrick MacDonald, University of Alberta, Canada

Tuesday, January 28 | 8:00AM - 9:00AM
Welcome and Keynote Address (Joint)
Room: Sweeney Ballroom A-E

Speaker 2 of 3
* Alan D. Attie, University of Wisconsin-Madison, USA

Tuesday, January 28 | 8:00AM - 9:00AM
Welcome and Keynote Address (Joint)
Room: Sweeney Ballroom A-E

Speaker 3 of 3
Morris J. Birnbaum, Pfizer Inc., USA
The Development of Therapeutics for T2DM and Related Diseases

Tuesday, January 28 | 9:00AM - 11:30AM
All About Insulin: Signaling, Secretion, and Action (Joint)
Room: Sweeney Ballroom A-E

Speaker 1 of 8
* Patrick MacDonald, University of Alberta, Canada

Tuesday, January 28 | 9:00AM - 11:30AM
All About Insulin: Signaling, Secretion, and Action (Joint)
Room: Sweeney Ballroom A-E

Speaker 2 of 8
* Barbara B. Kahn, Beth Israel Deaconess Medical Center, Harvard Medical School, USA

Tuesday, January 28 | 9:00AM - 11:30AM
All About Insulin: Signaling, Secretion, and Action (Joint)
Room: Sweeney Ballroom A-E

Speaker 3 of 8
Michael P. Czech, University of Massachusetts Medical School, USA
Molecular Mechanisms of Insulin Resistance

Tuesday, January 28 | 9:00AM - 11:30AM
All About Insulin: Signaling, Secretion, and Action (Joint)
Room: Sweeney Ballroom A-E


Coffee Break

Tuesday, January 28 | 9:00AM - 11:30AM
All About Insulin: Signaling, Secretion, and Action (Joint)
Room: Sweeney Ballroom A-E

Speaker 5 of 8
Maureen Anne Gannon, Vanderbilt University Medical Center, USA
Promoting ß-cell Survival and Preserving Functional ß-cell Mass by Targeting PGE2 Receptors

Tuesday, January 28 | 9:00AM - 11:30AM
All About Insulin: Signaling, Secretion, and Action (Joint)
Room: Sweeney Ballroom A-E

Speaker 6 of 8
Morris F. White, Boston Children's Hospital, Harvard Medical School, USA
The Systemic Integration of Hepatic Insulin Resistance

Tuesday, January 28 | 9:00AM - 11:30AM
All About Insulin: Signaling, Secretion, and Action (Joint)
Room: Sweeney Ballroom A-E

Speaker 7 of 8
Arya Mani, Yale University, USA
Short Talk: Mutations in the Cela2a Gene Unravel the Function of the Encoded Protein as a Novel Incretin

Tuesday, January 28 | 9:00AM - 11:30AM
All About Insulin: Signaling, Secretion, and Action (Joint)
Room: Sweeney Ballroom A-E

Speaker 8 of 8
Amelia K. Linnemann, Indiana University School of Medicine, USA
Short Talk: IFN-alpha Mediates Heterogenous ROS Accumulation in Human Islet Beta-Cells

Tuesday, January 28 | 11:30AM - 12:15PM
Lunch
Room: Sweeney F


Tuesday, January 28 | 12:00PM - 2:30PM
Poster Session 1
Room: Sweeney F


Tuesday, January 28 | 2:30PM - 3:30PM
Workshop: Therapeutic Strategies for Targeting Insulin Actio
n
Room: Sweeney Ballroom C-E

Speaker 1 of 5
* Silvia Corvera, University of Massachusetts Medical School, USA

Tuesday, January 28 | 2:30PM - 3:30PM
Workshop: Therapeutic Strategies for Targeting Insulin Actio
n
Room: Sweeney Ballroom C-E

Speaker 2 of 5
Thiago M. Batista, Joslin Diabetes Center, USA
Dissection of Protein Phosphorylation Networks Underlying Muscle Insulin Resistance in Type 2 Diabetes

Tuesday, January 28 | 2:30PM - 3:30PM
Workshop: Therapeutic Strategies for Targeting Insulin Actio
n
Room: Sweeney Ballroom C-E

Speaker 3 of 5
Jaroslawna Meister, NIDDK, National Institutes of Health, USA
Role of ß2-adrenergic Receptor Signaling in Skeletal Muscle Glucose Metabolism

Tuesday, January 28 | 2:30PM - 3:30PM
Workshop: Therapeutic Strategies for Targeting Insulin Actio
n
Room: Sweeney Ballroom C-E

Speaker 4 of 5
Paul M. Titchenell, University of Pennsylvania, USA
Regulation of Skeletal Muscle Metabolism by Insulin Signaling

Tuesday, January 28 | 2:30PM - 3:30PM
Workshop: Therapeutic Strategies for Targeting Insulin Actio
n
Room: Sweeney Ballroom C-E

Speaker 5 of 5
Jacqueline Stoeckli, University of Sydney, Australia
ABHD15: A Novel Player in Insulin Regulation of Lipolysis in Adipocytes

Tuesday, January 28 | 2:30PM - 4:30PM
Workshop 1: What Do GWAS Genes Do in Islets?
This session is from Islet Biology
Room: Sweeney Ballroom A-B

Speaker 1 of 9
* Karen L. Mohlke, University of North Carolina at Chapel Hill, USA


Tuesday, January 28 | 2:30PM - 4:30PM
Workshop 1: What Do GWAS Genes Do in Islets?
This session is from Islet Biology
Room: Sweeney Ballroom A-B

Speaker 2 of 9
* James D. Johnson, University of British Columbia, Canada


Tuesday, January 28 | 2:30PM - 4:30PM
Workshop 1: What Do GWAS Genes Do in Islets?
This session is from Islet Biology
Room: Sweeney Ballroom A-B

Speaker 3 of 9
Joseph Angleson, University of Denver, USA
Melanocortin Receptor-4 Regulates a-Cell Function and the Counter-Regulatory Response to Insulin-Induced Hypoglycemia in Mice


Tuesday, January 28 | 2:30PM - 4:30PM
Workshop 1: What Do GWAS Genes Do in Islets?
This session is from Islet Biology
Room: Sweeney Ballroom A-B

Speaker 4 of 9
Malin Fex, Lund University, Sweden
Loss of Melatonin Type 1A Receptor Results in Dysregulated Whole-Body Metabolism Characterised by Hyperglucagonemia, Glucose Intolerance and Enhanced Insulin Secretion


Tuesday, January 28 | 2:30PM - 4:30PM
Workshop 1: What Do GWAS Genes Do in Islets?
This session is from Islet Biology
Room: Sweeney Ballroom A-B

Speaker 5 of 9
YongKyung Kim, University of Colorado Anschutz Medical Campus, USA
PTPN2 Plays a Novel Role in the Beta Cells to Regulate Mitochondrial Function in Type 1 Diabetes Progression


Tuesday, January 28 | 2:30PM - 4:30PM
Workshop 1: What Do GWAS Genes Do in Islets?
This session is from Islet Biology
Room: Sweeney Ballroom A-B

Speaker 6 of 9
Taiyi Kuo, Columbia University, USA
Identification of C2CD4A as a Human Diabetes Susceptibility Gene with a Role in ß-Cell Insulin Secretion


Tuesday, January 28 | 2:30PM - 4:30PM
Workshop 1: What Do GWAS Genes Do in Islets?
This session is from Islet Biology
Room: Sweeney Ballroom A-B

Speaker 7 of 9
Haopeng Lin, Alberta Diabetes Institute, Canada
SENP1 in Compensation and Failure of Insulin Secretion with High-Fat Diet


Tuesday, January 28 | 2:30PM - 4:30PM
Workshop 1: What Do GWAS Genes Do in Islets?
This session is from Islet Biology
Room: Sweeney Ballroom A-B

Speaker 8 of 9
Dapeng Yang, Memorial Sloan Kettering Cancer Center, USA
Sequential CRISPR Screening Uncovers a Novel Role of HHEX in Specifying Human Pancreatic Differentiation


Tuesday, January 28 | 2:30PM - 4:30PM
Workshop 1: What Do GWAS Genes Do in Islets?
This session is from Islet Biology
Room: Sweeney Ballroom A-B

Speaker 9 of 9
Taylor S. Morriseau, University of Manitoba, Canada
New Insights into the HNF-1aG319S Variant in Early-Onset T2D Among Manitoba Indigenous Youth


Tuesday, January 28 | 3:30PM - 4:30PM
Panel Discussion
Room: Sweeney Ballroom C-E

Speaker 1 of 7
* David E. James, University of Sydney, Australia

Tuesday, January 28 | 3:30PM - 4:30PM
Panel Discussion
Room: Sweeney Ballroom C-E

Speaker 2 of 7
* Deborah M. Muoio, Duke University Medical Center, USA

Tuesday, January 28 | 3:30PM - 4:30PM
Panel Discussion
Room: Sweeney Ballroom C-E

Speaker 3 of 7
Morris J. Birnbaum, Pfizer Inc., USA

Tuesday, January 28 | 3:30PM - 4:30PM
Panel Discussion
Room: Sweeney Ballroom C-E

Speaker 4 of 7
Michael P. Czech, University of Massachusetts Medical School, USA

Tuesday, January 28 | 3:30PM - 4:30PM
Panel Discussion
Room: Sweeney Ballroom C-E

Speaker 5 of 7
Peter A. Crawford, University of Minnesota, USA

Tuesday, January 28 | 3:30PM - 4:30PM
Panel Discussion
Room: Sweeney Ballroom C-E

Speaker 6 of 7
Daniel P. Kelly, University of Pennsylvania, USA

Tuesday, January 28 | 3:30PM - 4:30PM
Panel Discussion
Room: Sweeney Ballroom C-E

Speaker 7 of 7
Barbara B. Kahn, Beth Israel Deaconess Medical Center, Harvard Medical School, USA

Tuesday, January 28 | 4:30PM - 5:00PM
Coffee Available
Room: Sweeney Ballroom Foyer


Tuesday, January 28 | 5:00PM - 7:00PM
Novel Approaches for Monitoring Carbon Traffic Control
Room: Sweeney Ballroom C-E

Speaker 1 of 6
* Peter A. Crawford, University of Minnesota, USA

Tuesday, January 28 | 5:00PM - 7:00PM
Novel Approaches for Monitoring Carbon Traffic Control
Room: Sweeney Ballroom C-E

Speaker 2 of 6
Joshua D. Rabinowitz, Princeton University, USA
Isotope Tracing for Deciphering Metabolic Network Usage

Tuesday, January 28 | 5:00PM - 7:00PM
Novel Approaches for Monitoring Carbon Traffic Control
Room: Sweeney Ballroom C-E

Speaker 3 of 6
David H. Wasserman, Vanderbilt University School of Medicine, USA
Extramyocellular Barriers to Insulin-Stimulated Muscle Glucose Uptake

Tuesday, January 28 | 5:00PM - 7:00PM
Novel Approaches for Monitoring Carbon Traffic Control
Room: Sweeney Ballroom C-E

Speaker 4 of 6
Barbara M. Bakker, University Medical Center Groningen, Netherlands
Modeling for Young and Old: Tackling the Complexity of Fatty Acid Oxidation in Metabolic Disease

Tuesday, January 28 | 5:00PM - 7:00PM
Novel Approaches for Monitoring Carbon Traffic Control
Room: Sweeney Ballroom C-E

Speaker 5 of 6
Maciek R. Antoniewicz, University of Delaware, USA
Short Talk: Metabolite Cross-Feeding Interactions in Adipocyte-Hepatocyte Co-Cultures Elucidated with a Novel 13C-Metabolic Flux Analysis Technique


Tuesday, January 28 | 5:00PM - 7:00PM
Novel Approaches for Monitoring Carbon Traffic Control
Room: Sweeney Ballroom C-E

Speaker 6 of 6
Jose M. Orozco, Massachusetts Institute of Technology, USA
Short Talk: Dihydroxyacetone Phosphate Signals Glucose Availability to mTORC1

Tuesday, January 28 | 5:00PM - 7:00PM
Islet Plasticity
This session is from Islet Biology
Room: Sweeney Ballroom A-B

Speaker 1 of 7
* Jean Buteau, University of Alberta, Canada


Tuesday, January 28 | 5:00PM - 7:00PM
Islet Plasticity
This session is from Islet Biology
Room: Sweeney Ballroom A-B

Speaker 2 of 7
* Bridget Wagner, Broad Institute, USA


Tuesday, January 28 | 5:00PM - 7:00PM
Islet Plasticity
This session is from Islet Biology
Room: Sweeney Ballroom A-B

Speaker 3 of 7
George K. Gittes, Children's Hospital of Pittsburgh of UPMC, USA
Beta Cell Neogenesis and Protection


Tuesday, January 28 | 5:00PM - 7:00PM
Islet Plasticity
This session is from Islet Biology
Room: Sweeney Ballroom A-B

Speaker 4 of 7
Julie B. Sneddon, University California, San Francisco, USA
Elucidating Human Endocrine Cell Fate Selection


Tuesday, January 28 | 5:00PM - 7:00PM
Islet Plasticity
This session is from Islet Biology
Room: Sweeney Ballroom A-B

Speaker 5 of 7
Seung K. Kim, Stanford University, USA
Alternative Systems to Study Pancreatic Islet Development and Function


Tuesday, January 28 | 5:00PM - 7:00PM
Islet Plasticity
This session is from Islet Biology
Room: Sweeney Ballroom A-B

Speaker 6 of 7
Christine A. Beamish, Houston Methodist Research Institute, USA
Short Talk: Loss of Endocrine Cell Identity Correlates with Pre-Surgical HOMA-ß in Patients with Chronic Pancreatitis Undergoing Islet Auto-Transplantation


Tuesday, January 28 | 5:00PM - 7:00PM
Islet Plasticity
This session is from Islet Biology
Room: Sweeney Ballroom A-B

Speaker 7 of 7
Mathieu Latreille, Imperial College London, UK
Short Talk: Beta-Cell Dedifferentiation Is Associated with Epithelial-Mesenchymal Transition In Diabetes


Tuesday, January 28 | 7:00PM - 7:00PM
On Own for Dinner


Wednesday, January 29 | 7:00AM - 8:00AM
Breakfast
Room: Sweeney F


Wednesday, January 29 | 8:00AM - 11:00AM
Ketones and Ketogenesis; Super-Fuel or Nuclear Signal?
Room: Sweeney Ballroom C-E

Speaker 1 of 7
* Judith A. Simcox, University of Wisconsin - Madison, USA

Wednesday, January 29 | 8:00AM - 11:00AM
Ketones and Ketogenesis; Super-Fuel or Nuclear Signal?
Room: Sweeney Ballroom C-E

Speaker 2 of 7
Richard Veech, NIAAA, National Institutes of Health, USA
The Effects of Ketone Body Metabolism on the Great Controlling Nucleotide Couples and their Application to Common Diseases

Wednesday, January 29 | 8:00AM - 11:00AM
Ketones and Ketogenesis; Super-Fuel or Nuclear Signal?
Room: Sweeney Ballroom C-E

Speaker 3 of 7
Peter A. Crawford, University of Minnesota, USA
Tracing the Role of Intrahepatic Ketone Turnover in Fatty Liver Disease

Wednesday, January 29 | 8:00AM - 11:00AM
Ketones and Ketogenesis; Super-Fuel or Nuclear Signal?
Room: Sweeney Ballroom C-E


Coffee Break

Wednesday, January 29 | 8:00AM - 11:00AM
Ketones and Ketogenesis; Super-Fuel or Nuclear Signal?
Room: Sweeney Ballroom C-E

Speaker 5 of 7
Daniel P. Kelly, University of Pennsylvania, USA
Ketones and Heart Failure

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