Monday, January 27 | 4:00PM - 8:00PM Arrival and Registration
Room: Sweeney Ballroom Foyer
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Monday, January 27 | 6:00PM - 8:00PM Welcome Mixer
Room: Sweeney F
No registration fees are used to fund alcohol served at this function.
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Tuesday, January 28 | 7:00AM - 8:00AM Breakfast
Room: Sweeney F
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Tuesday, January 28 | 7:30AM - 8:00AM Poster Setup
Room: Sweeney F
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Tuesday, January 28 | 8:00AM - 7:00PM Poster Viewing
Room: Sweeney F
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Tuesday, January 28 | 8:00AM - 9:00AM Welcome and Keynote Address (Joint)
Room: Sweeney Ballroom A-E
Speaker 1 of 3
* Patrick MacDonald, University of Alberta, Canada
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Tuesday, January 28 | 8:00AM - 9:00AM Welcome and Keynote Address (Joint)
Room: Sweeney Ballroom A-E
Speaker 2 of 3
* Alan D. Attie, University of Wisconsin-Madison, USA
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Tuesday, January 28 | 8:00AM - 9:00AM Welcome and Keynote Address (Joint)
Room: Sweeney Ballroom A-E
Speaker 3 of 3
Morris J. Birnbaum, Pfizer Inc., USA
The Development of Therapeutics for T2DM and Related Diseases
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Tuesday, January 28 | 9:00AM - 11:30AM All About Insulin: Signaling, Secretion, and Action (Joint)
Room: Sweeney Ballroom A-E
Speaker 1 of 8
* Patrick MacDonald, University of Alberta, Canada
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Tuesday, January 28 | 9:00AM - 11:30AM All About Insulin: Signaling, Secretion, and Action (Joint)
Room: Sweeney Ballroom A-E
Speaker 2 of 8
* Barbara B. Kahn, Beth Israel Deaconess Medical Center, Harvard Medical School, USA
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Tuesday, January 28 | 9:00AM - 11:30AM All About Insulin: Signaling, Secretion, and Action (Joint)
Room: Sweeney Ballroom A-E
Speaker 3 of 8
Michael P. Czech, University of Massachusetts Medical School, USA
Molecular Mechanisms of Insulin Resistance
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Tuesday, January 28 | 9:00AM - 11:30AM All About Insulin: Signaling, Secretion, and Action (Joint)
Room: Sweeney Ballroom A-E
Coffee Break
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Tuesday, January 28 | 9:00AM - 11:30AM All About Insulin: Signaling, Secretion, and Action (Joint)
Room: Sweeney Ballroom A-E
Speaker 5 of 8
Maureen Anne Gannon, Vanderbilt University Medical Center, USA
Promoting ß-cell Survival and Preserving Functional ß-cell Mass by Targeting PGE2 Receptors
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Tuesday, January 28 | 9:00AM - 11:30AM All About Insulin: Signaling, Secretion, and Action (Joint)Room: Sweeney Ballroom A-ESpeaker 6 of 8 Morris F. White, Boston Children's Hospital, Harvard Medical School, USA The Systemic Integration of Hepatic Insulin Resistance |
Tuesday, January 28 | 9:00AM - 11:30AM All About Insulin: Signaling, Secretion, and Action (Joint)Room: Sweeney Ballroom A-ESpeaker 7 of 8 Arya Mani, Yale University, USA Short Talk: Mutations in the Cela2a Gene Unravel the Function of the Encoded Protein as a Novel Incretin |
Tuesday, January 28 | 9:00AM - 11:30AM All About Insulin: Signaling, Secretion, and Action (Joint)Room: Sweeney Ballroom A-ESpeaker 8 of 8 Amelia K. Linnemann, Indiana University School of Medicine, USA Short Talk: IFN-alpha Mediates Heterogenous ROS Accumulation in Human Islet Beta-Cells |
Tuesday, January 28 | 11:30AM - 12:15PM Lunch
Room: Sweeney F
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Tuesday, January 28 | 12:00PM - 2:30PM Poster Session 1
Room: Sweeney F
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Tuesday, January 28 | 2:30PM - 3:30PM Workshop: Therapeutic Strategies for Targeting Insulin Actio
n
Room: Sweeney Ballroom C-E
Speaker 1 of 5
* Silvia Corvera, University of Massachusetts Medical School, USA
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Tuesday, January 28 | 2:30PM - 3:30PM Workshop: Therapeutic Strategies for Targeting Insulin Actio
n
Room: Sweeney Ballroom C-E
Speaker 2 of 5
Thiago M. Batista, Joslin Diabetes Center, USA
Dissection of Protein Phosphorylation Networks Underlying Muscle Insulin Resistance in Type 2 Diabetes
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Tuesday, January 28 | 2:30PM - 3:30PM Workshop: Therapeutic Strategies for Targeting Insulin ActionRoom: Sweeney Ballroom C-ESpeaker 3 of 5 Jaroslawna Meister, NIDDK, National Institutes of Health, USA Role of ß2-adrenergic Receptor Signaling in Skeletal Muscle Glucose Metabolism |
Tuesday, January 28 | 2:30PM - 3:30PM Workshop: Therapeutic Strategies for Targeting Insulin ActionRoom: Sweeney Ballroom C-ESpeaker 4 of 5 Paul M. Titchenell, University of Pennsylvania, USA Regulation of Skeletal Muscle Metabolism by Insulin Signaling |
Tuesday, January 28 | 2:30PM - 3:30PM Workshop: Therapeutic Strategies for Targeting Insulin Actio
n
Room: Sweeney Ballroom C-E
Speaker 5 of 5
Jacqueline Stoeckli, University of Sydney, Australia
ABHD15: A Novel Player in Insulin Regulation of Lipolysis in Adipocytes
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Tuesday, January 28 | 2:30PM - 4:30PM Workshop 1: What Do GWAS Genes Do in Islets?This session is from Islet Biology
Room: Sweeney Ballroom A-B
Speaker 1 of 9
* Karen L. Mohlke, University of North Carolina at Chapel Hill, USA |
Tuesday, January 28 | 2:30PM - 4:30PM Workshop 1: What Do GWAS Genes Do in Islets?This session is from Islet Biology
Room: Sweeney Ballroom A-B
Speaker 2 of 9
* James D. Johnson, University of British Columbia, Canada |
Tuesday, January 28 | 2:30PM - 4:30PM Workshop 1: What Do GWAS Genes Do in Islets?This session is from Islet Biology
Room: Sweeney Ballroom A-B
Speaker 3 of 9
Joseph Angleson, University of Denver, USA
Melanocortin Receptor-4 Regulates a-Cell Function and the Counter-Regulatory Response to Insulin-Induced Hypoglycemia in Mice |
Tuesday, January 28 | 2:30PM - 4:30PM Workshop 1: What Do GWAS Genes Do in Islets?This session is from Islet BiologyRoom: Sweeney Ballroom A-BSpeaker 4 of 9 Malin Fex, Lund University, Sweden Loss of Melatonin Type 1A Receptor Results in Dysregulated Whole-Body Metabolism Characterised by Hyperglucagonemia, Glucose Intolerance and Enhanced Insulin Secretion |
Tuesday, January 28 | 2:30PM - 4:30PM Workshop 1: What Do GWAS Genes Do in Islets?This session is from Islet Biology
Room: Sweeney Ballroom A-B
Speaker 5 of 9
YongKyung Kim, University of Colorado Anschutz Medical Campus, USA
PTPN2 Plays a Novel Role in the Beta Cells to Regulate Mitochondrial Function in Type 1 Diabetes Progression |
Tuesday, January 28 | 2:30PM - 4:30PM Workshop 1: What Do GWAS Genes Do in Islets?This session is from Islet Biology
Room: Sweeney Ballroom A-B
Speaker 6 of 9
Taiyi Kuo, Columbia University, USA
Identification of C2CD4A as a Human Diabetes Susceptibility Gene with a Role in ß-Cell Insulin Secretion |
Tuesday, January 28 | 2:30PM - 4:30PM Workshop 1: What Do GWAS Genes Do in Islets?This session is from Islet Biology
Room: Sweeney Ballroom A-B
Speaker 7 of 9
Haopeng Lin, Alberta Diabetes Institute, Canada
SENP1 in Compensation and Failure of Insulin Secretion with High-Fat Diet |
Tuesday, January 28 | 2:30PM - 4:30PM Workshop 1: What Do GWAS Genes Do in Islets?This session is from Islet BiologyRoom: Sweeney Ballroom A-BSpeaker 8 of 9 Dapeng Yang, Memorial Sloan Kettering Cancer Center, USA Sequential CRISPR Screening Uncovers a Novel Role of HHEX in Specifying Human Pancreatic Differentiation |
Tuesday, January 28 | 2:30PM - 4:30PM Workshop 1: What Do GWAS Genes Do in Islets?This session is from Islet BiologyRoom: Sweeney Ballroom A-BSpeaker 9 of 9 Taylor S. Morriseau, University of Manitoba, Canada New Insights into the HNF-1aG319S Variant in Early-Onset T2D Among Manitoba Indigenous Youth |
Tuesday, January 28 | 3:30PM - 4:30PM Panel Discussion
Room: Sweeney Ballroom C-E
Speaker 1 of 7
* David E. James, University of Sydney, Australia
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Tuesday, January 28 | 3:30PM - 4:30PM Panel Discussion
Room: Sweeney Ballroom C-E
Speaker 2 of 7
* Deborah M. Muoio, Duke University Medical Center, USA
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Tuesday, January 28 | 3:30PM - 4:30PM Panel Discussion
Room: Sweeney Ballroom C-E
Speaker 3 of 7
Morris J. Birnbaum, Pfizer Inc., USA
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Tuesday, January 28 | 3:30PM - 4:30PM Panel Discussion
Room: Sweeney Ballroom C-E
Speaker 4 of 7
Michael P. Czech, University of Massachusetts Medical School, USA
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Tuesday, January 28 | 3:30PM - 4:30PM Panel Discussion
Room: Sweeney Ballroom C-E
Speaker 5 of 7
Peter A. Crawford, University of Minnesota, USA
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Tuesday, January 28 | 3:30PM - 4:30PM Panel Discussion
Room: Sweeney Ballroom C-E
Speaker 6 of 7
Daniel P. Kelly, University of Pennsylvania, USA
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Tuesday, January 28 | 3:30PM - 4:30PM Panel Discussion
Room: Sweeney Ballroom C-E
Speaker 7 of 7
Barbara B. Kahn, Beth Israel Deaconess Medical Center, Harvard Medical School, USA
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Tuesday, January 28 | 4:30PM - 5:00PM Coffee Available
Room: Sweeney Ballroom Foyer
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Tuesday, January 28 | 5:00PM - 7:00PM Novel Approaches for Monitoring Carbon Traffic Control
Room: Sweeney Ballroom C-E
Speaker 1 of 6
* Peter A. Crawford, University of Minnesota, USA
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Tuesday, January 28 | 5:00PM - 7:00PM Novel Approaches for Monitoring Carbon Traffic ControlRoom: Sweeney Ballroom C-ESpeaker 2 of 6 Joshua D. Rabinowitz, Princeton University, USA Isotope Tracing for Deciphering Metabolic Network Usage |
Tuesday, January 28 | 5:00PM - 7:00PM Novel Approaches for Monitoring Carbon Traffic ControlRoom: Sweeney Ballroom C-ESpeaker 3 of 6 David H. Wasserman, Vanderbilt University School of Medicine, USA Extramyocellular Barriers to Insulin-Stimulated Muscle Glucose Uptake |
Tuesday, January 28 | 5:00PM - 7:00PM Novel Approaches for Monitoring Carbon Traffic Control
Room: Sweeney Ballroom C-E
Speaker 4 of 6
Barbara M. Bakker, University Medical Center Groningen, Netherlands
Modeling for Young and Old: Tackling the Complexity of Fatty Acid Oxidation in Metabolic Disease
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Tuesday, January 28 | 5:00PM - 7:00PM Novel Approaches for Monitoring Carbon Traffic ControlRoom: Sweeney Ballroom C-ESpeaker 5 of 6 Maciek R. Antoniewicz, University of Delaware, USA Short Talk: Metabolite Cross-Feeding Interactions in Adipocyte-Hepatocyte Co-Cultures Elucidated with a Novel 13C-Metabolic Flux Analysis Technique
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Tuesday, January 28 | 5:00PM - 7:00PM Novel Approaches for Monitoring Carbon Traffic Control
Room: Sweeney Ballroom C-E
Speaker 6 of 6
Jose M. Orozco, Massachusetts Institute of Technology, USA
Short Talk: Dihydroxyacetone Phosphate Signals Glucose Availability to mTORC1
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Tuesday, January 28 | 5:00PM - 7:00PM Islet PlasticityThis session is from Islet Biology
Room: Sweeney Ballroom A-B
Speaker 1 of 7
* Jean Buteau, University of Alberta, Canada |
Tuesday, January 28 | 5:00PM - 7:00PM Islet PlasticityThis session is from Islet Biology
Room: Sweeney Ballroom A-B
Speaker 2 of 7
* Bridget Wagner, Broad Institute, USA |
Tuesday, January 28 | 5:00PM - 7:00PM Islet PlasticityThis session is from Islet Biology
Room: Sweeney Ballroom A-B
Speaker 3 of 7
George K. Gittes, Children's Hospital of Pittsburgh of UPMC, USA
Beta Cell Neogenesis and Protection |
Tuesday, January 28 | 5:00PM - 7:00PM Islet PlasticityThis session is from Islet BiologyRoom: Sweeney Ballroom A-BSpeaker 4 of 7 Julie B. Sneddon, University California, San Francisco, USA Elucidating Human Endocrine Cell Fate Selection |
Tuesday, January 28 | 5:00PM - 7:00PM Islet PlasticityThis session is from Islet Biology
Room: Sweeney Ballroom A-B
Speaker 5 of 7
Seung K. Kim, Stanford University, USA
Alternative Systems to Study Pancreatic Islet Development and Function |
Tuesday, January 28 | 5:00PM - 7:00PM Islet PlasticityThis session is from Islet Biology
Room: Sweeney Ballroom A-B
Speaker 6 of 7
Christine A. Beamish, Houston Methodist Research Institute, USA
Short Talk: Loss of Endocrine Cell Identity Correlates with Pre-Surgical HOMA-ß in Patients with Chronic Pancreatitis Undergoing Islet Auto-Transplantation |
Tuesday, January 28 | 5:00PM - 7:00PM Islet PlasticityThis session is from Islet BiologyRoom: Sweeney Ballroom A-BSpeaker 7 of 7 Mathieu Latreille, Imperial College London, UK Short Talk: Beta-Cell Dedifferentiation Is Associated with Epithelial-Mesenchymal Transition In Diabetes |
Tuesday, January 28 | 7:00PM - 7:00PM On Own for Dinner
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Wednesday, January 29 | 7:00AM - 8:00AM Breakfast
Room: Sweeney F
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Wednesday, January 29 | 8:00AM - 11:00AM Ketones and Ketogenesis; Super-Fuel or Nuclear Signal?
Room: Sweeney Ballroom C-E
Speaker 1 of 7
* Judith A. Simcox, University of Wisconsin - Madison, USA
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Wednesday, January 29 | 8:00AM - 11:00AM Ketones and Ketogenesis; Super-Fuel or Nuclear Signal?
Room: Sweeney Ballroom C-E
Speaker 2 of 7
Richard Veech, NIAAA, National Institutes of Health, USA
The Effects of Ketone Body Metabolism on the Great Controlling Nucleotide Couples and their Application to Common Diseases
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Wednesday, January 29 | 8:00AM - 11:00AM Ketones and Ketogenesis; Super-Fuel or Nuclear Signal?Room: Sweeney Ballroom C-ESpeaker 3 of 7 Peter A. Crawford, University of Minnesota, USA Tracing the Role of Intrahepatic Ketone Turnover in Fatty Liver Disease |
Wednesday, January 29 | 8:00AM - 11:00AM Ketones and Ketogenesis; Super-Fuel or Nuclear Signal?
Room: Sweeney Ballroom C-E
Coffee Break
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Wednesday, January 29 | 8:00AM - 11:00AM Ketones and Ketogenesis; Super-Fuel or Nuclear Signal?Room: Sweeney Ballroom C-ESpeaker 5 of 7 Daniel P. Kelly, University of Pennsylvania, USA Ketones and Heart Failure |