B Cell Renaissance: Epigenetics, Regulation and Immunotherapy

joint with T Cell Memory

Organizer(s): Paolo Casali, Nicole Baumgarth, Meinrad Busslinger and Elizabeth Leadbetter

Sponsored by BioLegend, Inc.

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Summary of Meeting:

This conference will bring together experts in B cell biology to discuss the most recent advances in B cell research. Studies on B cell formation, from initial development, maturation, effector or memory development, and terminal differentiation have made researchers more appreciative of the molecular changes, including epigenetic marks, modifications and factors that control and modulate development and differentiation in the functional role of B cells. The complexities of B cell differentiation pathways through germinal centers and extra-follicular foci in primary lymphoid organs, in addition to novel interactions in diverse secondary lymphoid tissues, are also under intense study in both mice and humans. Conference sessions will cover the interactions of B cells with lymphoid cells, non-lymphoid cells, and secreted factors in a myriad of environments. This will help elucidate the numerous factors which influence and ultimately dictate the contribution of each unique B cell subset to homeostasis, immune defense or immunopathology. Understanding the drivers of B cell differentiation and function will enable precise harnessing of these key elements to optimize the immuno-therapeutic effect of B cells and their antibodies in autoimmune disease, infection, and cancer.

Scholarship Deadline: November 5 2019

Discounted Abstract Deadline: November 5 2019

Abstract Deadline: December 4 2019

Discounted Registration Deadline: January 8 2020

Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested.

Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:

We gratefully acknowledge additional support from these exhibitors at this conference:

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Genentech, Inc.

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI149884-01
Funding for this conference was made possible (in part) by 1R13AI149884-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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