Neurodegeneration: The Biological Pathways Driving the Future of Therapeutic Development

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MEETING CANCELLED: Neurodegeneration: The Biological Pathways Driving the Future of Therapeutic Development
joint with MEETING CANCELLED: Neuro-Immune Interactions in the Central Nervous System
Scientific Organizers: Dimitri Krainc and Alfred W. Sandrock Jr.
Date: June 19 - 23, 2020
Location: Keystone Resort, Keystone, CO, USA
Sponsored by BioLegend, Inc., Roche and Ionis Pharmaceuticals, Inc.
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Summary of Meeting:
Neurodegenerative diseases remain one of the main concerns for aging populations across the world. Elucidating the molecular mechanisms underlying these diseases thus remains a priority for developing effective therapeutics to combat them. Recent genetic studies linked to these diseases have pointed to functional defects in several key cellular organelles and pathways that appear to drive neurodegeneration, including endolysosomal, mitochondrial and synaptic dysfunctions. However, there is still much to be learned regarding the precise roles of these pathways in disease progression, their contribution to neuronal vulnerability, and how to effectively target these pathways in patients. Important mechanistic themes in neurodegenerative disease include the genetics of neuro-immune interactions, the involvement of synaptic molecular events, the role of endolysosomal, autophagic and mitochondrial dysfunction, the potential contribution of dynamic inter-organelle contact sites in neurons, and translational considerations including the use of biomarkers and gene therapy. The goal of this conference is to bring together fundamental basic scientists who are experts in these areas of cell biology, together with clinicians and medical researchers, and scientists investigating therapeutic strategies for neurodegeneration. By combining these different fields of expertise, this conference will stimulate cross-fertilization, in-depth interactions and insightful discussions on disease pathogenesis and strategies for advancing drug development for neurodegenerative disorders. Finally, this conference is being paired with a conference on Neuro-Immune Interactions in the Central Nervous System. This combination will be beneficial in that it will emphasize the crossover between neurodegeneration and neuroimmunology. As neuroimmunology is a recently reinvigorated field, this meeting will provide a critical opportunity to foster cross-disciplinary thinking.
Meeting has been cancelled. Please call our office if you have questions at 970-262-1230 or 1-800-253-0685.


Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
BioLegend, Inc.Ionis Pharmaceuticals, Inc.Roche
We gratefully acknowledge additional support for this conference from:
American Society of Gene & Cell Therapy (ASGCT)Charles River
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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