Oct 01–04, 2023 | Whistler Conference Centre, Whistler, BC, Canada
Scientific Organizers:
Tullia C. Bruno, Brad H. Nelson, Daniel Hollern, and Marie-Caroline Dieu-Nosjean

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Scientific Organizers: Tullia C. Bruno, Brad H. Nelson, Daniel Hollern, and Marie-Caroline Dieu-Nosjean
Tullia C. Bruno
Brad H. Nelson
Daniel Hollern
Marie-Caroline Dieu-Nosjean
***Meeting program subject to change.
Available Formats: = In Person = On DemandBooking Function
Fundraising
Sunday, October 1, 2023
Monday, October 2, 2023
Session Chair
Session Chair
Session Chair
Session Chair
Hyperactivated PI3Kd, in a Human Primary Immunodeficiency, Influences Tfh and Germinal Centers, Altering Self and Commensal Reactivity and Humoral Immunity
Modulation of B Cell Function in Breast Cancer
B Cell Function Within Ovarian Cancer Patients
The Role of Natural Antibodies in Anti-Tumor Immunity
Session Chair
Session Chair
Achieving Reproducible Maturation Staging of Tertiary Lymphoid Structures: from Imaging Mass Cytometry Data to Pathology Applications
B Cells and Tertiary Lymphoid Structures can Predict Prostate Cancer Outcomes
Biomarkers of Functionally Active Tertiary Lymphoid Structures in Human Breast Cancer
Crosstalk Between Tumour-Infiltrating B cells, Tertiary Lymphoid Structures and Lymph Nodes in Triple Negative Breast Cancer
Spatial Transcriptomics Identifies Subtypes of Lymphoid Aggregates and their Key Gene Signatures in Human Glioblastoma
Machine Learning Integrating Spatial Transcriptomics and Proteomics Uncovers Patterns of B Cell Response in Intratumoral Tertiary Lymphoid Structures in Pancreatic Cancer Pathologic Responders
Organ-specific Determinants of Lymphoid Neogenesis in Human Kidney and Lung Cancer
Session Chair
Session Chair
Modulating Tertiary Lymphoid Structure Formation in Non-Small Cell Lung Cancer Patients
Tertiary Lymphoid Structures and B Cells in Immunotherapy Response
Cellular and Molecular Mechanisms Driving Development of Tertiary Lymphoid Structures in Cancer
Short Talk: Short Talk: Dissecting Germinal Centre Responses in Human and Murine Lung Cancer
Short Talk: Short Talk: Germinal Centre B Cells are Affected by Neuronal Density in Colorectal Cancer
Tuesday, October 3, 2023
Session Chair
Session Chair
Unexpected Tumor-Reactive Antibodies
Neoantigen-Driven B Cell and CD4 T Follicular Helper Cell Collaboration Promotes Anti-Tumor CD8 T Cell
Meningeal Inflammation in Multiple Sclerosis – What Are B Cells Doing?
The Importance of Tfh and Germinal Centers in Regulating Immunodominance for Vaccines Against Challenging Targets
Short Talk: Short Talk: Microbiota Induced Humoral Immunity is Driven by Autonomous Skin-intrinsic Germinal Centers
Short Talk: Short Talk: The Activity of Tertiary Lymphoid Structures in High Grade Serous Ovarian Cancer is Governed by Site, Stroma, and Cellular Interactions
Professor of Medicine
President, Chief Executive Officer and Co-Founder
Senior Group Leader
Earl Stadtman Investigator & Chief, Transcription Systems Dynamics and Biology Unit
Session Chair
Session Chair
Manipulating the Tumor-Stromal Interface for Improved Function of Tertiary Lymphoid Structure
T/B Cell-Antigen Specific Murine Models of Lung Cancer to Study TLS in Neoadjuvant Immunotherapy
Diet and Microbiome Control of the Tumor Immune Microenvironment
Short Talk: Short Talk: Are ILC3 Recruited to Inflamed Lungs Involved in the Neogenesis of Pulmonary Tertiary Lymphoid Structures?
Short Talk: Short Talk: MAdCAM-1+ Tumor-associated High Endothelial Venules are Key for LIGHT-mediated Anti-glioma Immunity
Wednesday, October 4, 2023
Session Chair
Session Chair
The Importance of Antigen Specificity for Intratumoral B Cell Function
Determinants of B Cell Fate and Function in Cancer
TAC-001, a Toll-Like Receptor (TLR9) Agonist Antibody Conjugate Targeting B Cells, Promotes Anti-Tumor Immunity
Short Talk: Short Talk: B Cells Empower Th17 Cells to Regress Solid Tumors
Short Talk: Short Talk: MAGE-A4 Induces Lung Adenocarcinoma via Accumulation of Immunosuppressive Plasma Cells
Short Talk: Short Talk: B-Cell Receptor (BCR) Repertoire and Antibody Recognition Analysis of Melanoma Patients Treated with Neoadjuvant Immune Checkpoint Blockade (ICB)
Short Talk: Short Talk: Circulating and Intratumoral Extrafollicular Memory B Cells have Reduced Effector Function and Correlate with Advanced Disease
Session Chair
Session Chair
Defining HPV-specific B Cell Responses in Patients with Head and Neck Cancer
Inhibition of Semaphorin 4D in Combination with Immune Checkpoint Therapy Promotes Organized Lymphoid Structures within the Tumor Microenvironment that Correlate with Clinical Outcome
Engineering Plasma Cells for Tumor Eradication
Seeing is B-lieving: Discovering the Target Antigens and Effector Functions of Tumor-infiltrating B Cells
Self-reactive T Helper Cells Promote B Cell Responses in Ovarian Cancer Patients
Presence of CD11c+ B Cells with Potent Effector Memory Phenotype in Non-small Cell Lung Cancer
Immune Landscape of Tertiary Lymphoid Structures in Hepatocellular Carcinoma Treated with Neoadjuvant Immune Checkpoint Blockade
Inhibition of Plasma Cell Differentiation Promotes Antitumor Immunity
Session Chair
Engineering B Cells for Experimental or Clinical Use
The Importance of B Cells in Adoptive Cell Therapies
Engineered B Cells To Accelerate Antigen Presentation in Oncology
Tfh and Germinal Center B Cells: Key Constituents of Functionally Active Tertiary Lymphoid Structures and Anti-Tumor Immunity
Thursday, October 5, 2023
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