Joint with: From Systems Immunology to Immunoengineering
Immunometabolism Across Scales: From Cells to Systems to Healthspan
Jan 11–14, 2026 | Fairmont Hotel Vancouver, Vancouver, BC, Canada
Scientific Organizers:
Susan M Kaech, Vishwa Deep Dixit, and Dequina Angelina Nicholas
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Jan 11–14, 2026 | Fairmont Hotel Vancouver, Vancouver, BC, Canada
Scientific Organizers: Susan M Kaech, Vishwa Deep Dixit, and Dequina Angelina Nicholas
Susan M Kaech
The Salk Institute
Vishwa Deep Dixit, PhD
Yale University
Dequina Angelina Nicholas, PhD
University of California, Irvine
Available Formats:
Supported by the Directors' Fund
Livestream
In Person
On Demand
***Meeting program subject to change.
Available Formats: = Livestream = In Person = On DemandSunday, January 11, 2026
Fundraising
Booking Function
Merchandise Options
Registration Options
Registration
4:00–8:00 PM
British Columbia Foyer
Welcome Mixer
6:00–8:00 PM
British Columbia Foyer
Monday, January 12, 2026
Breakfast
7:30–8:30 AM
Vancouver Island Room
Welcome and Keynote Session (Joint)
8:30–10:00 AM
British / Columbia Ballroom
Marcia C. Haigis, Harvard Medical School
Investigating the Role of Metabolites in Immune Cells across Scales: Spanning Molecules and Cells to the Host
Investigating the Role of Metabolites in Immune Cells across Scales: Spanning Molecules and Cells to the Host
Christina S. Leslie, Memorial Sloan-Kettering Cancer Center
T Cell Mediated Immunity; Chromatin States; Comp Bio
T Cell Mediated Immunity; Chromatin States; Comp Bio
Coffee Break
10:00–10:20 AM
British Columbia Foyer
Award Recipient Acknowledgement
10:20–10:25 AM
British / Columbia Ballroom
Inside the Cell's Kitchen: Mastering the Art of Nutrient Signaling (Joint)
10:25–12:25 PM
British / Columbia Ballroom
Dequina Angelina Nicholas, University of California, Irvine
Metabolite Control of Immune Cell Specificity
Metabolite Control of Immune Cell Specificity
Eicke Latz, University of Bonn
Myeloid Cell Signaling/Immunometabolism/Personalized Medicine
Myeloid Cell Signaling/Immunometabolism/Personalized Medicine
Steven J. Bensinger, University of California, Los Angeles
Regulation of Immune Cell Function by Lipid Metabolism
Regulation of Immune Cell Function by Lipid Metabolism
Greg M Delgoffe †, University of Pittsburgh
Short Talk: Postprandial Alterations to Systemic Metabolism Durably Enhance T Cell Immunity
Short Talk: Postprandial Alterations to Systemic Metabolism Durably Enhance T Cell Immunity
Joel Babdor †, University of Pennsylvania
Short Talk: Microbiome Mediators Control the Immune Tone in Health and Disease
Short Talk: Microbiome Mediators Control the Immune Tone in Health and Disease
Poster Setup
12:25–1:00 PM
British / Columbia Ballroom
On Own for Lunch
12:25–2:30 PM
Poster Viewing
1:00–10:00 PM
British / Columbia Ballroom
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Columbia Ballroom
Hannah Bumgarner †, University of Pittsburgh
When Feast is just as bad as Famine: Hyperglycemic Cell Culture Drives T Cell Dysfunction
When Feast is just as bad as Famine: Hyperglycemic Cell Culture Drives T Cell Dysfunction
Chih-Hao Chang †, The Jackson Laboratory
Mitochondrial Pyruvate Oxidation Licenses RUNX3-Driven Tim-3 via p300-Dependent Acetylation to Limit CTL Function
Mitochondrial Pyruvate Oxidation Licenses RUNX3-Driven Tim-3 via p300-Dependent Acetylation to Limit CTL Function
Yusuke Endo †, KAZUSA DNA Research Institute
The Novel Function of Lipid Flux on RORγt-mediated Th17 Cell Pathogenicity
The Novel Function of Lipid Flux on RORγt-mediated Th17 Cell Pathogenicity
SeongJun Han †, Harvard University
Metabolic Reprogramming of CD8+ T Cells with Aging Impairs Anti-Tumor Immunity
Metabolic Reprogramming of CD8+ T Cells with Aging Impairs Anti-Tumor Immunity
Dustin Hancks †, University of Texas Southwestern Medical Center
Mitochondrial ETC Activity Licenses Temporal Progression of Immune States at the Proteome Level
Mitochondrial ETC Activity Licenses Temporal Progression of Immune States at the Proteome Level
Injae Hwang, Perelman School of Medicine, University of Pennsylvania
Unraveling the Switchable Roles of Ketone Body Metabolism of Mesenchymal Stromal Cells in Regulating Adipose Tissue Inflammation and Insulin Resistance
Unraveling the Switchable Roles of Ketone Body Metabolism of Mesenchymal Stromal Cells in Regulating Adipose Tissue Inflammation and Insulin Resistance
Ramiah D Jacks, The Ohio State University
Rapid Adipose Tissue Expansion Triggers Proliferation of Memory Adipose Tissue T cells and Accumulation of Novel “T helper 2 (Th2) Regulatory” Cells
Rapid Adipose Tissue Expansion Triggers Proliferation of Memory Adipose Tissue T cells and Accumulation of Novel “T helper 2 (Th2) Regulatory” Cells
Ichiro Katahira †, Universitätsklinikum Düsseldorf
Controlling Mitochondrial Membrane Architecture Via MIC60 Determines Viral Replication To Promote Anti-viral Immunity
Controlling Mitochondrial Membrane Architecture Via MIC60 Determines Viral Replication To Promote Anti-viral Immunity
Coffee Available
4:30–5:00 PM
British Columbia Foyer
Immune Adaptation to Tissue Metabolic Ecosystems
5:00–7:00 PM
Columbia Ballroom
Russell G. Jones, Van Andel Research Institute
Nutrient Preference in Control of Adaptive Immune Responses
Nutrient Preference in Control of Adaptive Immune Responses
Lydia Lynch, Princeton University
Metabolic Adaptations of Innate Lymphocytes in Tissues
Metabolic Adaptations of Innate Lymphocytes in Tissues
Amy Yu †, Harvard University
Short Talk: One-Carbon Metabolism Sustains Effector T Cell Function Through Cell-Surface Glycosylation
Short Talk: One-Carbon Metabolism Sustains Effector T Cell Function Through Cell-Surface Glycosylation
Santosha A Vardhana, Memorial Sloan Kettering Cancer Center
Short Talk: Systemic Iron Sequestration Limits Intratumoral CD8+ T Cell Responses in Pancreas Cancer
Short Talk: Systemic Iron Sequestration Limits Intratumoral CD8+ T Cell Responses in Pancreas Cancer
Social Hour with Dinner
7:00–8:00 PM
Vancouver Island Room
Poster Session 1
7:30–10:00 PM
British / Columbia Ballroom
Tuesday, January 13, 2026
Breakfast
7:30–8:30 AM
Vancouver Island Room
Microbial Metabolites at the Crossroads of Nutrition and Immunity
8:30–11:30 AM
Columbia Ballroom
Manuela Raffatellu, University of California, San Diego
Microbial-Derived Metabolites at the Host-Pathogen Interface
Microbial-Derived Metabolites at the Host-Pathogen Interface
Noah W. Palm, Yale University
Gut Microbiome- Metabolome-Immune Communication Networks
Gut Microbiome- Metabolome-Immune Communication Networks
Dan R. Littman, HHMI/New York University School of Medicine
Role of Sulfur-Containing Amino Acids on Organismal Immunometabolic Response
Role of Sulfur-Containing Amino Acids on Organismal Immunometabolic Response
Sagar P Bapat, University of California, San Francisco
Short Talk: Dietary Timing Dictates Inflammatory Memory in Skin
Short Talk: Dietary Timing Dictates Inflammatory Memory in Skin
Felix Hartmann †, German Cancer Research Center
Short Talk: Spatial Proteomics Identifies Lactate-Competent CD8⁺ T cells as a Feature of Response to Checkpoint Inhibition in Melanoma
Short Talk: Spatial Proteomics Identifies Lactate-Competent CD8⁺ T cells as a Feature of Response to Checkpoint Inhibition in Melanoma
Andrea Graziani †, Università di Torino
Short Talk: Diacylglycerol Kinase alpha (DGKα) Couples Antigen-induced T Cell Activation to the Negative Feedback Mechanism Leading to TCR and CAR Ubiquitination and Lysosomal Degradation
Short Talk: Diacylglycerol Kinase alpha (DGKα) Couples Antigen-induced T Cell Activation to the Negative Feedback Mechanism Leading to TCR and CAR Ubiquitination and Lysosomal Degradation
Benjamin Y Winer †, Memorial Sloan Kettering Cancer Center
Short Talk: Pushing the Envelope: Regulation of Myeloid Plasma Membrane Abundance and its Effect of Cellular Decision Making
Short Talk: Pushing the Envelope: Regulation of Myeloid Plasma Membrane Abundance and its Effect of Cellular Decision Making
Coffee Break
9:30–9:50 AM
British Columbia Foyer
Poster Setup
11:30–1:00 PM
British / Columbia Ballroom
On Own for Lunch
11:30–3:15 PM
Poster Viewing
1:00–10:00 PM
British / Columbia Ballroom
Meet the Pioneers (Joint)
3:15–4:30 PM
Columbia Ballroom
Coffee Available
4:30–5:00 PM
British Columbia Foyer
Neuro-Immune Regulation of Immune Function and Metabolism
5:00–7:00 PM
Columbia Ballroom
Ana Domingos, University of Oxford
Sympathetic Control of Immunity
Sympathetic Control of Immunity
Susan M Kaech, The Salk Institute
Fueling T Cell Responses in Cancer
Fueling T Cell Responses in Cancer
Christina Camell, University of Minnesota
Catecholamines and GDFs in Regulation of Adipose Immunometabolism
Catecholamines and GDFs in Regulation of Adipose Immunometabolism
Judy J Lee †, Johns Hopkins University
Short Talk: Lipid Metabolism Regulates Fate Decision of Oligodendrocyte Precursor Cells in Multiple Sclerosis Lesions
Short Talk: Lipid Metabolism Regulates Fate Decision of Oligodendrocyte Precursor Cells in Multiple Sclerosis Lesions
Ekaterina Vinogradova, Rockefeller University
Short Talk: Chemical Proteomic Approaches to Study and Modulate T Cell Function
Short Talk: Chemical Proteomic Approaches to Study and Modulate T Cell Function
Social Hour with Dinner
7:00–8:00 PM
Vancouver Island Room
Poster Session 2
7:30–10:00 PM
British / Columbia Ballroom
Wednesday, January 14, 2026
Breakfast
7:30–8:30 AM
Vancouver Island Room
Immunometabolic Control of Aging and Healthspan
8:30–11:30 AM
Columbia Ballroom
Vishwa Deep Dixit, Yale University
Immunometabolic Checkpoints of Aging
Immunometabolic Checkpoints of Aging
Phillip West, The Jackson Laboratory
Mitochondrial Control of Innate Immunity in Disease and Aging
Mitochondrial Control of Innate Immunity in Disease and Aging
Andrea Ablasser, Ecole Polytechnique Fédérale de Lausanne
Talk Title to be Announced
Talk Title to be Announced
Jonathan D. Powell, Calico Life Sciences
The Immunometabolism of Immunoaging
The Immunometabolism of Immunoaging
Michael S Dahabieh, Van Andel Institute
Short Talk: Immune Checkpoints Reimagined: Lipid–Protein Control of T Cell Exhaustion
Short Talk: Immune Checkpoints Reimagined: Lipid–Protein Control of T Cell Exhaustion
Farnaz Shamsi †, New York University
Short Talk: Inflammaging of the Brown Adipose Immune Niche Orchestrates Age-Related Decline
Short Talk: Inflammaging of the Brown Adipose Immune Niche Orchestrates Age-Related Decline
Coffee Break
9:30–9:50 AM
British Columbia Foyer
On Own for Lunch
11:30–2:30 PM
Symposia Spotlight 2: Rising Stars
2:30–4:30 PM
Columbia Ballroom
Yae Rin Jeon †, Yonsei University College of Medicine, Seoul, South Korea
PPAR-α Reprograms Lipid Metabolism to Define Macrophage Fate in Chronic Mycobacterium Avium Infection
PPAR-α Reprograms Lipid Metabolism to Define Macrophage Fate in Chronic Mycobacterium Avium Infection
Sushanth Kumar †, Duke University
Understanding the Mechanisms by which Maternal High-Fat Diet Leads to Sex-Specific Dysfunction of the Serotonin System in Offspring
Understanding the Mechanisms by which Maternal High-Fat Diet Leads to Sex-Specific Dysfunction of the Serotonin System in Offspring
Julio Ayala Angulo †, University of California, Irvine
CD1a-Mediated Inflammation Modulates Metabolism in High Fat Diet Mouse Model of T2D
CD1a-Mediated Inflammation Modulates Metabolism in High Fat Diet Mouse Model of T2D
Megan H Le †, University of Washington
Metabolic Profiling Identifies Distinct Immune Cell Phenotypes at the Maternal-Fetal Interface across Pregnancy
Metabolic Profiling Identifies Distinct Immune Cell Phenotypes at the Maternal-Fetal Interface across Pregnancy
Isaiah Little †, UNIVERSITY OF CALIFORNIA, LOS ANGELES: TARLING LAB
Investigating Lipid-Mediated Regulation of Type III Interferon in Pulmonary Disease
Investigating Lipid-Mediated Regulation of Type III Interferon in Pulmonary Disease
Corinna Mayer †, Karolinska Institutet
Spatial and Functional Dissection of Immune-metabolic Dynamics in the Human Endometrium across the Menstrual Cycle
Spatial and Functional Dissection of Immune-metabolic Dynamics in the Human Endometrium across the Menstrual Cycle
Andrew Monteith †, University of Tennessee-Knoxville
Acute Fasting Impairs Neutrophil Metabolism and Exacerbates Susceptibility to Staphylococcus Aureus Bacteremia
Acute Fasting Impairs Neutrophil Metabolism and Exacerbates Susceptibility to Staphylococcus Aureus Bacteremia
Noga Ron-Harel †, Technion-Israel Institute of Technology
Heme and Iron Toxicity in the Aged Spleen Impairs T-cell Immunity through Iron Deprivation
Heme and Iron Toxicity in the Aged Spleen Impairs T-cell Immunity through Iron Deprivation
Coffee Available
4:30–5:00 PM
British Columbia Foyer
Systems Metabolism in Health and Disease (Joint)
5:00–6:00 PM
British / Columbia Ballroom
Leif S Ludwig, Berlin Institute of Health and Max Delbrück Center for Molecular Medicine
Single-Cell Multi-Omics of Mitochondrial DNA Disorders
Single-Cell Multi-Omics of Mitochondrial DNA Disorders
Stacey D Finley, University of Southern California
Signaling and Metabolic States in Immunotherapy
Signaling and Metabolic States in Immunotherapy
Closing Keynote Address (Joint)
6:00–6:45 PM
British / Columbia Ballroom
Jeffrey C Rathmell, University of Chicago
Immunometabolism in Health and Disease
Immunometabolism in Health and Disease
Meeting Wrap-Up: Outcomes and Future Directions (Joint)
6:45–7:00 PM
British / Columbia Ballroom
Social Hour with Dinner
7:00–8:00 PM
Vancouver Island Room
Cash Bar
8:00–11:00 PM
Entertainment
8:00–11:00 PM
Thursday, January 15, 2026
Departure
12:00–11:59 PM
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