Non-Coding RNA Biology: New Roles and Diversity
Jan 27–30, 2025 | Keystone Resort, Keystone, CO, United States
Scientific Organizers:
Sebastian Kadener, Irene Bozzoni, and Luisa Cochella
In Person
On Demand
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Jan 27–30, 2025 | Keystone Resort, Keystone, CO, United States
Scientific Organizers: Sebastian Kadener, Irene Bozzoni, and Luisa Cochella
Sebastian Kadener
Irene Bozzoni
Luisa Cochella
Available Formats:
Supported by:
In Person
On Demand
***Meeting program subject to change.
Available Formats: = In Person = On DemandMonday, January 27, 2025
Booking Function
Merchandise Options
Registration Options
Registration
4:00–8:00 PM
Longs Peak Foyer
Welcome Mixer
6:00–8:00 PM
Longs Peak Foyer
Tuesday, January 28, 2025
Breakfast
7:30–8:30 AM
Quandary Peak
Welcome and Keynote Address (Joint)
8:30–9:45 AM
Longs/Grays Peaks
* Sebastian Kadener, Brandeis University
Session Chair
Session Chair
V. Narry Kim, Seoul National University Institute for Basic Science
Cellular Regulation of Exogenous Rnas: from Viral Rnas to Mrna Therapeutics
Cellular Regulation of Exogenous Rnas: from Viral Rnas to Mrna Therapeutics
Coffee Break
9:45–10:05 AM
Longs Peak Foyer
RNA Biology and Immune System Diseases (Joint)
10:05–12:05 PM
Longs/Grays Peaks
* Sun Hur, Harvard Medical School
Session Chair
Session Chair
Noam Stern-Ginossar, Weizmann Institute of Science
Viral Pathogenesis and RNAs
Viral Pathogenesis and RNAs
Schraga Schwartz, Weizmann Institute of Science
Charting the Ribosomal Epitranscriptome
Charting the Ribosomal Epitranscriptome
Judy Lieberman, Boston Children's Hospital; Harvard University
RNA Therapeutics to Modulate Tumor Immunity
RNA Therapeutics to Modulate Tumor Immunity
Max Lauring, Columbia University Medical Center
Short Talk: An Anti-Retrotransposon Silencing Mechanism Promotes Antibody Diversification
Short Talk: An Anti-Retrotransposon Silencing Mechanism Promotes Antibody Diversification
Ignacio Ruiz Fernández, Spanish National Centre for Cardiovascular Research
Short Talk: T Cell-derived miR-721 as a Key Player in Inflammaging and Age-related Diseases
Short Talk: T Cell-derived miR-721 as a Key Player in Inflammaging and Age-related Diseases
Award Recipient Acknowledgement (Joint)
10:20–10:25 AM
Longs Peak Foyer
Poster Setup
12:00–1:00 PM
Quandary Peak
On Own for Lunch
12:00–2:30 PM
Poster Viewing
1:00–10:00 PM
Quandary Peak
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Longs Peak
* Andrea Ventura, Memorial Sloan Kettering Cancer Center
Session Chair
Session Chair
Philippe J Batut, Columbia University
Non-coding RNAs and Genome Organization Control the Dynamics of Gene Expression during Development
Non-coding RNAs and Genome Organization Control the Dynamics of Gene Expression during Development
Jazmin Morales, Brandeis University
Investigating the Role of circMbl in Neural Function and Development
Investigating the Role of circMbl in Neural Function and Development
Joseph Rosenbluh, Monash University
Systematic Loss-of-function Screens Identify Pathway-specific Functional Circular RNAs
Systematic Loss-of-function Screens Identify Pathway-specific Functional Circular RNAs
Debraj Manna, Indian Institute of Science
Regulation of the Expression of Ribosomal Proteins by Small Downstream ORFs
Regulation of the Expression of Ribosomal Proteins by Small Downstream ORFs
Jinbiao Ma, Fudan University
Cryo-EM Structures of IStron-encoded Group I Intron Reveal Molecular Mechanism of Antagonistic Conflict with TnpB Associated Guide RNA
Cryo-EM Structures of IStron-encoded Group I Intron Reveal Molecular Mechanism of Antagonistic Conflict with TnpB Associated Guide RNA
Neve Auperin, Pasteur Institute
Soma-to-Germline miRNA Inheritance via Yolk Promotes Stress Resilience in Progeny
Soma-to-Germline miRNA Inheritance via Yolk Promotes Stress Resilience in Progeny
Karine G Le Roch, University of California, Riverside
Novel Insights into the Role of Long Non-coding RNA in the Human Malaria Parasite, Plasmodium Falciparum
Novel Insights into the Role of Long Non-coding RNA in the Human Malaria Parasite, Plasmodium Falciparum
Coffee Available
4:30–5:00 PM
Longs Peak Foyer
Non-Coding RNA and Chromatin
5:00–7:00 PM
Longs Peak
* Philippe J Batut, Columbia University
Session Chair
Session Chair
Donal O'Carroll, University of Edinburgh
Small RNAs and De Novo DNA Methylation
Small RNAs and De Novo DNA Methylation
Yehu Moran, Hebrew University of Jerusalem
Characterization of the Antiviral RNAi in Cnidarians Sheds Light on Mechanistic Evolution and Diversity
Characterization of the Antiviral RNAi in Cnidarians Sheds Light on Mechanistic Evolution and Diversity
Tim Hasenbein, Technical University of Munich (TUM)
Short Talk: X-linked Deletion of Crossfirre, Firre, and Dxz4 in vivo Uncovers Diverse Phenotypes and Combinatorial Effects on Autosomes
Short Talk: X-linked Deletion of Crossfirre, Firre, and Dxz4 in vivo Uncovers Diverse Phenotypes and Combinatorial Effects on Autosomes
Claire Rougeulle, CNRS / Institut Curie
Non-coding RNAs Controlling X Chromosome Activity in Primates
Non-coding RNAs Controlling X Chromosome Activity in Primates
Social Hour with Lite Bites
7:00–8:00 PM
Quandary Peak
Poster Session 1
7:30–10:00 PM
Quandary Peak
Wednesday, January 29, 2025
Breakfast
7:00–8:00 AM
Quandary Peak
Post-Transcriptional Control by Non-Coding RNAs
8:00–11:00 AM
Longs Peak
* Irene Bozzoni, University La Sapienza, Rome
Session Chair
Session Chair
Luisa Cochella, Johns Hopkins University School of Medicine
Quantitative microRNA-Mediated Repression in Animal Development
Quantitative microRNA-Mediated Repression in Animal Development
Joshua T Mendell, University of Texas Southwestern Medical Center
Regulation and Function of Mammalian Noncoding RNAs
Regulation and Function of Mammalian Noncoding RNAs
Gaspare La Rocca, University of Palermo
Non-Coding RNAs in Cancer and Development
Non-Coding RNAs in Cancer and Development
Peter Wang, MIT
Short Talk: The Structural Basis for RNA Slicing by Human Argonaute2
Short Talk: The Structural Basis for RNA Slicing by Human Argonaute2
Mariangela Morlando, Sapienza University of Rome
Short Talk: Functional Insights into circDlc1(2): A Key Regulator of microRNA Localization and Synaptic Translation in Neurons
Short Talk: Functional Insights into circDlc1(2): A Key Regulator of microRNA Localization and Synaptic Translation in Neurons
Martin J Simard, CHU de Québec-Université Laval Research Center
Short Talk: Dipeptidyl Peptidase DPF-3 is a Gatekeeper of MicroRNA Argonaute Compensation in Animals
Short Talk: Dipeptidyl Peptidase DPF-3 is a Gatekeeper of MicroRNA Argonaute Compensation in Animals
Francesca Briganti, UCSD
Short Talk: The Use of miRNA for the Identification of Etiology Specific Compensatory Mechanisms in Heart Disease
Short Talk: The Use of miRNA for the Identification of Etiology Specific Compensatory Mechanisms in Heart Disease
Coffee Break
9:00–9:20 AM
Longs Peak Foyer
Poster Setup
11:00–1:00 PM
Quandary Peak
On Own for Lunch
11:00–2:45 PM
Career Roundtable (Joint)
1:00–2:30 PM
Grays Peak
Damian Refojo, Max Planck Partner Institute - Buenos Aires
Principal Investigator
Principal Investigator
Jorge Henao-Mejia, University of Pennsylvania and Children's Hospital of Philadelphia
Professor
Professor
Emily M Anderson, Revvity, Inc.
Principal Scientist
Principal Scientist
Xiaoyi Yuan, UTHealth Houston
Assistant Professor
Assistant Professor
Poster Viewing
1:00–10:00 PM
Quandary Peak
Panel: Methodologies to Study Non-Coding RNAs: Standards and Best Practices
2:45–4:30 PM
Longs Peak
* Luisa Cochella, Johns Hopkins University School of Medicine
Panelist
Panelist
Roy R. Parker, HHMI/University of Colorado
Panelist
Panelist
Yunsun Nam, University of Texas Southwestern Medical Center
Panelist
Panelist
Donal O'Carroll, University of Edinburgh
Panelist
Panelist
Yehu Moran, Hebrew University of Jerusalem
Panelist
Panelist
Coffee Available
4:30–5:00 PM
Longs Peak Foyer
Granules and RNA Localization
5:00–7:00 PM
Longs Peak
* Scott G. Kennedy, Harvard Medical School
Session Chair
Session Chair
Irene Bozzoni, University La Sapienza, Rome
circRNA in the Control of Translation and RNA Trafficking
circRNA in the Control of Translation and RNA Trafficking
Roy R. Parker, HHMI/University of Colorado
Role of RNA in Granule Function and Structure
Role of RNA in Granule Function and Structure
Marie Laure Baudet, University of Trento
Intracellular Distribution of RNA and Association with Different Organelles
Intracellular Distribution of RNA and Association with Different Organelles
Scott G. Kennedy, Harvard Medical School
Non-Templated Addition of a G-Quadruplex Structure Marks RNA for Small RNA Production
Non-Templated Addition of a G-Quadruplex Structure Marks RNA for Small RNA Production
Social Hour with Lite Bites
7:00–8:00 PM
Quandary Peak
Poster Session 2
7:30–10:00 PM
Quandary Peak
Thursday, January 30, 2025
Breakfast
7:00–8:00 AM
Quandary Peak
Novel Functions of Non-Coding RNAs
8:00–11:00 AM
Longs Peak
* Mariangela Morlando, Sapienza University of Rome
Session Chair
Session Chair
Damian Refojo, Max Planck Partner Institute - Buenos Aires
The Influence of circTulp4 on Emotional Behavior and Synaptic Function
The Influence of circTulp4 on Emotional Behavior and Synaptic Function
Christine Mayr, Memorial Sloan Kettering Cancer Center
The Location of Protein Synthesis Controls The Activity of Transcriptional Regulators in the Nucleus
The Location of Protein Synthesis Controls The Activity of Transcriptional Regulators in the Nucleus
Yunsun Nam, University of Texas Southwestern Medical Center
Structure Function Analysis of RNA Modifying Enzymes
Structure Function Analysis of RNA Modifying Enzymes
Sebastian Kadener, Brandeis University
Molecular and Physiological Functions of circRNAs
Molecular and Physiological Functions of circRNAs
Bodu Liu, Cold Spring Harbor Laboratory
Short Talk: A Casein Kinase 2 Interacting LncRNA Regulates Cellular Plasticity of Breast Cancer by Stabilizing c-Myc
Short Talk: A Casein Kinase 2 Interacting LncRNA Regulates Cellular Plasticity of Breast Cancer by Stabilizing c-Myc
Coffee Break
9:00–9:20 AM
Longs Peak Foyer
Meet the Editors (Joint)
11:00–12:00 PM
Longs Peak
Mishtu Dey, Cell Chemical Biology, Cell Press
*Session Chair, Editor-in-Chief
*Session Chair, Editor-in-Chief
Gail Teitzel, Cell Press
Deputy Editor
Deputy Editor
Iris Marchal, Springer Nature AG & Co. KG
Associate Editor, Reviews
Associate Editor, Reviews
Yehu Moran, Hebrew University of Jerusalem
Academic Editor, EMBO Press
Academic Editor, EMBO Press
On Own for Lunch
11:00–2:30 PM
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions
3:00–4:30 PM
Longs Peak
* Yehu Moran, Hebrew University of Jerusalem
Session Chair
Session Chair
Yael Sarusi, Weizmann Institute of Science
CHASERR-targeting antisense oligonucleotides boost CHD2 levels and affect mouse behavior in a model of CHD2 haploinsufficiency
CHASERR-targeting antisense oligonucleotides boost CHD2 levels and affect mouse behavior in a model of CHD2 haploinsufficiency
Jackson B Trotman, University of North Carolina at Chapel Hill
Xist Repeat A Coordinates an Assembly of SR Proteins to Mediate Gene Silencing
Xist Repeat A Coordinates an Assembly of SR Proteins to Mediate Gene Silencing
Guifeng Wei, University of Oxford
N6-methyladenosine and the NEXT complex direct Xist RNA turnover and X inactivation dynamics
N6-methyladenosine and the NEXT complex direct Xist RNA turnover and X inactivation dynamics
Takahisa Furukawa, Osaka University
Single cell/nucleus RNA-Seq analysis revealed in vivo functional mechanisms of central nervous system-specific miR-124a in mouse development
Single cell/nucleus RNA-Seq analysis revealed in vivo functional mechanisms of central nervous system-specific miR-124a in mouse development
Chelsea Drown, University of Colorado Boulder
Investigation of MeCP2-RNA Targets in Rett Syndrome Neurodevelopmental Disorder
Investigation of MeCP2-RNA Targets in Rett Syndrome Neurodevelopmental Disorder
Coffee Available
4:30–5:00 PM
Longs Peak Foyer
RNA and Therapeutics (Joint)
5:00–6:45 PM
Longs/Grays Peaks
* Uttiya Basu, Columbia University
Session Chair
Session Chair
Jorge Henao-Mejia, University of Pennsylvania and Children's Hospital of Philadelphia
RNA Regulation of Tumor Associated Macrophages
RNA Regulation of Tumor Associated Macrophages
Trey Westbrook, Baylor College of Medicine
Targeting RNA Splicing in Cancer: From Synthetic Lethality to Immuno-Oncology
Targeting RNA Splicing in Cancer: From Synthetic Lethality to Immuno-Oncology
Michael G Kharas, Memorial Sloan Kettering Cancer Center
RNA Methylation and Control of Cellular Fate in the Blood
RNA Methylation and Control of Cellular Fate in the Blood
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Longs/Grays Peaks
Social Hour with Lite Bites
7:00–8:00 PM
Quandary Peak
Trivia
8:00–9:00 PM
Longs Peak
Cash Bar
8:00–9:00 PM
Quandary Peak
Friday, January 31, 2025
Fundraising
Departure
12:00–11:59 PM
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