Joint with: RNA Modifications in Health and Disease
Regulatory RNAs: Emerging Mechanisms

Dec 12–15, 2023 | Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers: Mitchell Guttman, Phillip D. Zamore, and Maite Huarte

  In Person
  On Demand
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Dec 12–15, 2023 | Fairmont Banff Springs, Banff, AB, Canada

Scientific Organizers: Mitchell Guttman, Phillip D. Zamore, and Maite Huarte

Supported by the  Directors' Fund

***Meeting program subject to change.

Available Formats:   = In Person     = On Demand
Tuesday, December 12, 2023
Registration  
4:00–8:00 PM
 Van Horne Foyer
Welcome Mixer  
6:00–8:00 PM
 Van Horne Foyer
Wednesday, December 13, 2023
Breakfast  
7:00–8:00 AM
 Van Horne C
Welcome and Keynote Address (Joint)  
8:00–9:00 AM
 Van Horne A
* Mitchell Guttman, California Institute of Technology
Session Chair
* Eric A. Miska, University of Cambridge
Session Chair
Caroline Dean, John Innes Centre
Antisense-Mediated Chromatin Silencing
RNAs in Immune Defenses (Joint)  
9:00–11:15 AM
 Van Horne A
* Faezeh Jame-Chenarboo, University of Alberta
Session Chair
Sandra L. Wolin, NCI, National Institutes of Health
Nicked tRNAs: Surveillance and Roles as Regulatory RNAs
Eckhard Jankowsky, Moderna
Talk Title to be Announced
Stacy M. Horner, Duke University Medical Center
RNA Modifications at the Virus-host Interface
Christian Bellodi, Lund University
Short Talk: Short Talk: A New Role for the Pseudouridine Synthase 10 (PUS10) in Retrotransposon-driven Inflammation
Diana Dou, Stanford University
Short Talk: Short Talk: Xist Ribonucleoproteins Promote Female Sex-biased Autoimmunity
Coffee Break  
9:30–9:50 AM
 Van Horne Foyer
Poster Setup  
11:15–1:00 PM
 President's Hall
On Own for Lunch  
11:15–5:00 PM
Poster Viewing  
1:00–10:00 PM
 President's Hall
* Eugene W. Yeo, University of California, San Diego
Session Chair
Workshop: Cutting-Edge RNA Methods  
3:00–4:30 PM
 Van Horne B
Coffee Available  
4:30–5:00 PM
 Van Horne Foyer
RNAs in Chromatin Regulation  
5:00–7:00 PM
 Van Horne B
* Yilin Lu, Georgia Institute of Technology
Session Chair
Asifa Akhtar, Max Planck Institute of Immunobiology and Epigenetics
Epigenetic Mechanisms of Histone Acetylation by Long Non-Coding RNA
Edith Heard, European Molecular Biology Laboratory
Mechanisms of Gene Silencing and Dosage Regulation During X-Chromosome Inactivation
Phillip D. Zamore, University of Massachusetts Medical School
piRNAs, PIWI Proteins, Across the Animal Kingdom
Howard Y. Chang, Stanford University
Non-Coding RNAs in Chromatin Regulation
Josien van Wolfswinkel, Yale University
Short Talk: Short Talk: Crosstalk Between Regulatory RNA Pathways in Planarian Genome Defense
Shannon Bailey, University of Massachusetts Chan Medical School
Short Talk: Short Talk: How Does GTSF1 Accelerate Target RNA Cleavage by PIWI-clade Argonaute Proteins?
Jimmy Guo, Caltech
Short Talk: Short Talk: SPIDR: A Highly Multiplexed Method for Mapping RNA-protein Interactions Uncovers Novel RBP Functions and Indicates that PRC2 Does Not Directly Bind RNA in vivo
Chen Davidovich, Monash University
Short Talk: Short Talk: Inseparable RNA Binding and Chromatin Modification Activities of a Nucleosome-interacting Surface in PRC2
Social Hour with Lite Bites  
7:00–8:00 PM
 Van Horne C
Poster Session 1  
7:30–10:00 PM
 President's Hall
Thursday, December 14, 2023
Breakfast  
7:00–8:00 AM
 Van Horne C
RNAs in Translational Control, mRNA Stability, and Post-Transcriptional Gene Regulation  
8:00–11:00 AM
 Van Horne B
Eliezer Calo, Massachusetts Institute of Technology
RNAs in Translational Control, mRNA Stability, and Post-Transcriptional Gene Regulation
Yukihide Tomari, University of Tokyo
Regulation of Gene Expression by Small RNAs
V. Narry Kim, Seoul National University Institute for Basic Science
Regulation and Biogenesis of microRNA
Joshua T. Mendell, University of Texas Southwestern Medical Center
Target-Directed Destruction of Argonaute Proteins and their microRNA Guides
Coffee Break  
9:00–9:20 AM
 Van Horne Foyer
Poster Setup  
11:00–1:00 PM
 President's Hall
On Own for Lunch  
11:00–5:00 PM
Poster Viewing  
1:00–10:00 PM
 President's Hall
Career Roundtable (Joint)  
3:00–4:30 PM
 Van Horne A
Coffee Available  
4:30–5:00 PM
 Van Horne Foyer
RNA as Specificity Determinants  
5:00–7:00 PM
 Van Horne B
* Shannon Bailey, University of Massachusetts Chan Medical School
Session Chair
Oliver J. Rando, University of Massachusetts Medical School
Small RNAs in Reproductive Biology
Ian MacRae, The Scripps Research Institute
Molecular Bases for Gene Regulation in miRNA and piRNA Systems
Laura Landweber, Columbia University
Mechanisms of RNA-Guided Genome Rearrangement in the Ciliate Oxytricha
Paula Cohen, Cornell University
Non-Canonical Roles for Argonautes in Sex Chromosome Regulation During Mammalian Meiosis
Social Hour with Lite Bites  
7:00–8:00 PM
 Van Horne C
Poster Session 2  
7:30–10:00 PM
 President's Hall
Friday, December 15, 2023
Breakfast  
7:00–8:00 AM
 Van Horne C
Roles of ncRNAs in Nuclear and Cytoplasmic Compartmentalization  
8:00–11:00 AM
 Van Horne B
Roy R. Parker, HHMI/University of Colorado
RNA-Mediated Granules
Richard A. Young, Whitehead Institute for Biomedical Research
RNA and Nuclear Condensates
Coffee Break  
9:00–9:20 AM
 Van Horne Foyer
On Own for Lunch  
11:00–5:00 PM
Coffee Available  
4:30–5:00 PM
 Van Horne Foyer
RNAs and DNA Organization  
5:00–6:45 PM
 Van Horne B
* Jimmy Guo, Caltech
Session Chair
* Diana Dou, Stanford University
Session Chair
Thomas R. Cech, HHMI/University of Colorado
How Might Molecular Condensates Enhance the Action of RNA-binding Proteins?
Mitchell Guttman, California Institute of Technology
RNA Promotes the Formation of Spatial Compartments in the Nucleus
Maite Huarte, Universidad de Navarra
Noncoding RNA Roles in the Coordination of DNA Replication and Stress Signaling
Jonathan E. Henninger, Whitehead Institute for Biomedical Research
Short Talk: Short Talk: RNA Binding by Transcription Factors in Health and Disease
Yilin Lu, Georgia Institute of Technology
Short Talk: Short Talk: Double Strand Break Repair Mediated by RNA Transcripts in Yeast and Human Cells
Prashant Bhat, California Institute of Technology
Short Talk: Short Talk: 3D Genome Organization Around Nuclear Speckles Drives mRNA Splicing Efficiency
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)  
6:45–7:00 PM
 Van Horne B
Social Hour with Lite Bites  
7:00–8:00 PM
 Van Horne C
Entertainment  
7:30–8:00 PM
 Van Horne C
Cash Bar  
8:00–9:00 PM
 Van Horne C
Saturday, December 16, 2023
Departure  
12:00–11:59 PM

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