Progress in Antibiotic Discovery and Development

Jan 01–04, 2027 | Location to be Determined
Scientific Organizers: Cesar de la Fuente, James J. Collins, and Ewa Szczurek

  In Person
  On Demand
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Jan 01–04, 2027 | Location to be Determined

Scientific Organizers: Cesar de la Fuente, James J. Collins, and Ewa Szczurek

Supported by the  Directors' Fund

***Meeting program subject to change.

Available Formats:   = In Person     = On Demand
Friday, January 1, 2027
Registration
4:00–8:00 PM
Welcome Mixer
6:00–8:00 PM
Saturday, January 2, 2027
Breakfast
7:00–8:00 AM
Welcome and Keynote Address
8:00–9:00 AM
Roy Kishony †, Technion – Israel Institute of Technology
The Future of Antibiotic Resistance
Antibiotics AI: Computational & AI-Enabled Antibiotic Discovery
9:00–10:45 AM
James J. Collins, Broad Institute of MIT & Harvard
AI Approaches for Antibiotic Discovery
Cesar de la Fuente, University of Pennsylvania
Accelerating Antibiotic Discovery Using AI
Ewa Szczurek, Helmholtz Munich
Controllable Generative AI for Antimicrobial Peptides Discovery
Short Talk(s) Chosen from Abstracts
Coffee Break
9:30–9:50 AM
Panel Discussion 1: Q&A with Drs. Collins, de la Fuente and Szczurek
10:45–11:15 AM
Poster Setup
11:15–1:00 PM
On Own for Lunch
11:15–5:00 PM
Poster Viewing
1:00–10:00 PM
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Alternative Approaches to Antibiotics
5:00–7:00 PM
Manuela Raffatellu †, University of California, San Diego
Harnessing Iron Acquisition Machinery to Target Pathogens
Deborah T. Hung †, Broad Institute of MIT & Harvard
Anti-Virulence Approaches to Target Pathogens
Shura Mankin †, University of Illinois
Novel Concepts in Ribosomal Inhibition
Jörg Vogel †, University of Würzburg
The Promises and Challenges of Programmable RNA Antibiotics
Short Talk(s) Chosen from Abstracts
Social Hour with Dinner
7:00–8:00 PM
Posters
7:30–10:00 PM
Sunday, January 3, 2027
Breakfast
7:00–8:00 AM
Natural-Product Biosynthesis and Engineering
8:00–11:00 AM
Gerry D. Wright †, McMaster University
The Natural History of Antibiotic Resistance
Allison Lopatkin †, University of Rochester
Predictive Biology: Understanding and Reversing the Evolution of Antibiotic Resistance
Helen I. Zgurskaya †, University of Oklahoma
Efflux Pumps and Antimicrobial Resistance
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
Panel Discussion 2: The Next Generation of Antibiotic Hunters (inspiring new people into the field)
11:00–12:00 PM
Jo Handelsman †, University of Wisconsin-Madison
Erin Duffy †, Boston University & CARB-X
Paul E. Turner †, Yale University
Poster Setup
11:00–1:00 PM
On Own for Lunch
11:00–5:00 PM
Poster Viewing
1:00–10:00 PM
Career Roundtable
3:00–4:30 PM
Coffee Available
4:30–5:00 PM
Antibiotic Discovery and Host Immunity
5:00–7:00 PM
Yifat Merbl †, Weizmann Institute of Science
Immune Proteasomes: An Untapped Source of Encrypted Peptide Antibiotics
Olga Shevchuk †, University Hospital Essen
Production of Encrypted Peptide Antibiotics in Human Kidney Infections
Short Talk(s) Chosen from Abstracts
Social Hour with Dinner
7:00–8:00 PM
Posters
7:30–10:00 PM
Monday, January 4, 2027
Breakfast
7:00–8:00 AM
Frontiers in Non-Traditional Antimicrobials: Phages, Peptides & Beyond
8:00–11:00 AM
Paul E. Turner †, Yale University
Phage Therapy to Combat Infections by Antibiotic-Resistant Bacterial Pathogens
Rino Rappuoli †, Fondazione Biotecnopolo di Siena
Vaccines against AMR
Man-Wah Tan †, Genentech, Inc.
Novel Inhibitors against Gram-negative Pathogens
Renee Fleeman †, University of Central Florida
Novel Antimicrobial Approaches Against Klebsiella
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
On Own for Lunch
12:30–5:00 PM
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Translating Antibiotics into the Clinic
5:00–5:50 PM
Tommaso Biancalani †, Genentech
Talk Title to be Announced
Erin Duffy †, Boston University & CARB-X
Talk Title to be Announced
David Payne †, GlaxoSmithKline
Talk Title to be Announced
Panel Discussion 3: Q&A with Drs. Biancalani and Duffy
5:50–6:20 PM
Machine Learning and Antimicrobial Peptides
6:20–7:30 PM
Jiangning Song †, Monash University
Machine Learning for Antimicrobial Peptide Design and Discovery
Daniela Kalafatovic †, University of Rijeka
Self-Assembling Peptide Design with Generative AI
Short Talk(s) Chosen from Abstracts
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
7:30–7:45 PM
Social Hour with Dinner
7:45–8:45 PM
Cash Bar
8:00–11:00 PM
Entertainment
8:00–11:00 PM
Tuesday, January 5, 2027
Departure
12:00–11:59 PM

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