Appetite regulation is a fundamental neurobiological process with far-reaching implications for public health, particularly in the context of obesity, eating disorders, and metabolic diseases. Despite rapid advances in neuroscience and metabolism, critical gaps remain in our understanding of how complex neuronal circuits integrate internal states and external cues to control feeding behavior. The primary goal of the “Neuronal Control of Appetite” meeting is to catalyze transformative progress in deciphering the neural mechanisms that govern appetite, with a focus on driving innovative research, cross-disciplinary collaboration, and translational insight. The meeting aims to challenge entrenched models of homeostatic control by highlighting emerging evidence of dynamic, context-dependent neural modulation. This meeting is deliberately designed to convene a diverse array of participants, including systems and behavioral neuroscientists, endocrinologists, computational modelers, clinical researchers, and biotech innovators. By bridging traditionally siloed domains, such as neural circuit mapping and metabolic disease modeling, the meeting will encourage the synthesis of ideas and techniques across fields. These interactions will foster durable collaborations, seed joint projects, and promote a holistic understanding of appetite regulation. Attendees will leave with a deeper understanding of the field’s trajectory, novel conceptual frameworks, and actionable ideas for interdisciplinary research.