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April Fellow's Spotlight on Dr. Vivien Maltez
Our April Fellow's Spotlight goes to Dr. Vivien Maltez, PhD, an Assistant Professor in the Division of Allergy,...
Due to an inherent fascination with parasitic helminthes, De’Broski R. Herbert earned a B.S. in Microbiology from Xavier University of Louisiana (1994) and a Ph.D. in Immunology from Thomas Jefferson Medical College (2000). His thesis work demonstrated a critical role for IL-5, B-1 lymphocytes, and eosinophils in host-protective immunity against Strongyloides stercoralis (J Immunol. 2000 Oct 15;165(8):4544-51).
As part of a life-long dream, De’Broski spent several years in South Africa to complete his post-doctoral training at the University of Cape Town in the laboratory of Frank Brombacher Ph.D. This resulted in seminal work that demonstrated IL-4/IL-13-driven alternative macrophage activation controls lethal immunopathology during Schistosoma mansoni infection (Immunity. 2004 May;20 (5):623-35).
Subsequently, he joined the laboratory of Fred. D. Finkelman M.D. and published multiple studies focused on the importance of IL-4/IL-13 in driving host-protection against parasitic helminthes through direct regulation of tissue macrophage function (J Immunol. 2010 Jun 1;184(11):6438-46) and mucosal epithelia (J Exp Med. 2009 Dec 21;206(13):2947-57).
As principal investigator of his independent laboratory at Cincinnati Children’s Research Foundation, his work focused upon elucidating mechanisms of innate Type 2 cytokine regulation by Trefoil factor family proteins (J Exp Med. 2012 Mar 12;209 (3):607-22) and immunosuppressivemacrophage subsets in the context of helminth infection and allergic inflammation (Eur J Immunol. 2011 Jul;41(7):2000-9,
Am J Pathol. 2012 May;180(5):2001-8).
Currently positioned as associate professor of Infectious Immunology in the Department of Pathobiology at UPENN, his laboratory is investigating mechanisms of host protection against helminthes, Type 2 inflammation, and the resolution of chronic mucosal inflammation in several model systems.
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Apr 23, 2025 by Shannon Weiman
Our April Fellow's Spotlight goes to Dr. Vivien Maltez, PhD, an Assistant Professor in the Division of Allergy,...
Apr 22, 2025 by Shannon Weiman
Keystone Symposia was founded on the idea of bringing academic and industry scientists together to accelerate...