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October Keystone Symposia Fellow's Spotlight on Dr. Brea Manuel
Our October Keystone Symposia Fellow's Spotlight features Dr. Brea Manuel, a post-doctoral researcher at the University...
I am Jonathan Silver, I have a BS in Biology from UNC-Chapel Hill and a PhD in Immunology from the University of Pennsylvania. As a graduate student at UPenn I studied in the lab of Dr. Chris Hunter, where I investigated the role of the gp130 family of cytokines (IL-6 and IL-27 in particular) in mediating the innate immune response to the parasite Toxoplasma gondii. Following my PhD I did a postdoctoral fellowship at Medimmune working with Dr. Alison Humbles where I studied the role of the alarmin IL-33 in mediating exaggerated anti-viral immune responses in a mouse model of COPD. I also studied functional and phenotypic plasticity in Type 2 innate lymphoid cells. My postdoctoral work culminated in a departmental Golden Pipette award, company-wide Scientific Publication of the Year and a patent application for manipulation of ILC plasticity in COPD exacerbations. I am currently Associate Director for Regeneron's Therapeutic Area Genetics (Immunology and Infectious Diseases). I am passionate about collaborating with colleagues to get the most out of our science and to drive our programs forward to ultimately help patients living with debilitating conditions.
Research Area(s):
ImmunologyResearch Keywords:
Mentor: Kizzmekia Corbett, PhD
Oct 28, 2025 by Keystone Symposia
Our October Keystone Symposia Fellow's Spotlight features Dr. Brea Manuel, a post-doctoral researcher at the University...
Sep 23, 2025 by Shannon Weiman
Featuring...