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April Fellow's Spotlight on Dr. Vivien Maltez
Our April Fellow's Spotlight goes to Dr. Vivien Maltez, PhD, an Assistant Professor in the Division of Allergy,...
I investigate how seizures during different periods of neurodevelopment result in long-term changes in learning and memory, social behavior, and repetitive/stereotyped behaviors. I also investigate the neural mechanisms that mediate these changes through molecular and imaging techniques. In particular, I am examining how seizures induce changes in the mTOR, MAPK, and Canonical Wnt signaling pathways and how these changes lead to alterations in potassium channels and other synaptic proteins. My interest in examining behavioral changes is also why I am examining the link between autism and epilepsy. Children with epilepsy have a high comorbidity with autism but the underlying mechanism is not known. I plan to investigate how seizures could lead to autistic-like behavior in mice. My third research question is how seizures during early development impact brain growth and bone growth. We use genetic and chemoconvulant models of epilepsy and determine their bone phenotype in adulthood.
Research Area(s):
NeurobiologyResearch Keywords:
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Apr 23, 2025 by Shannon Weiman
Our April Fellow's Spotlight goes to Dr. Vivien Maltez, PhD, an Assistant Professor in the Division of Allergy,...
Apr 22, 2025 by Shannon Weiman
Keystone Symposia was founded on the idea of bringing academic and industry scientists together to accelerate...