The Keystone Symposium on Precision Genome Engineering will highlight transformative advances that are reshaping the future of genetic medicine by pushing the boundaries of what is possible with genome editing technologies. As the field evolves from proof-of-concept to therapeutic application, critical questions around efficiency, specificity, safety, delivery, and scalability remain. This conference will address these gaps by convening world leaders and emerging innovators to explore next-generation tools, delivery strategies, integrative technologies, and clinical findings that are redefining genome engineering.

The program is designed to showcase cutting-edge research while fostering cross-disciplinary dialogue and collaboration. Attendees will engage in sessions covering innovation in editing systems, viral and non-viral delivery approaches, safety and specificity assessments, and the convergence of genome biology with artificial intelligence. These outcomes will be further advanced by the concurrent Keystone Symposium on Tissue-Specific Delivery of Genetic Medicines. Keynote addresses and joint sessions will emphasize in vivo applications and translational readiness, providing a comprehensive view of the field’s trajectory.

The symposium will bring together genome engineers, molecular biologists, delivery experts, AI scientists, and translational researchers—providing a dynamic platform to exchange ideas, form new collaborations, and stay at the forefront of scientific and technological innovation.

What sets this symposium apart is its deep focus on the precision and evolution of genome editing itself—ranging from mechanistic insights to therapeutic design—paired with timely discussions on how AI and delivery systems are accelerating discovery. Attendees will leave with an overview of where the field is headed and how to contribute to its next breakthroughs.