Cardiometabolism and Interorgan Crosstalk: Novel Mechanisms and Therapies

Feb 15–19, 2027 | Beaver Run Conference Center, Breckenridge, CO, United States
Scientific Organizers: Saptarsi M. Haldar, Karol E. Watson, and David A Kass

  In Person
  On Demand
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Feb 15–19, 2027 | Beaver Run Conference Center, Breckenridge, CO, United States

Scientific Organizers: Saptarsi M. Haldar, Karol E. Watson, and David A Kass

Supported by the  Directors' Fund

***Meeting program subject to change.

Available Formats:   = In Person     = On Demand
Monday, February 15, 2027
Registration
4:00–8:00 PM
Welcome Mixer
6:00–8:00 PM
Tuesday, February 16, 2027
Welcome and Keynote Address
4:00–5:00 PM
Daniel J. Drucker, Lunenfeld-Tanenbaum Research Institute
Mechanisms of Incretin Therapy and their CV and Neurological Benefits
Target Discovery and Patient Segmentation in Cardiometabolic Disease: AI and Human Genetics
5:00–7:00 PM
Luca Lotta, Regeneron Pharmaceuticals Inc.
Human Genetics at the Intersection of Metabolism and CV Risk
Rajat Gupta, Massachusetts General Hospital
Functional Genomics and Perturbational Screening for Cardiometabolic Target Discovery
Anna Helgadottir †, Decode genetics
Metabolic Drivers of CVD and Implications for Clinical Trial Enrichment
Short Talk(s) Chosen from Abstracts
Wednesday, February 17, 2027
Breakfast
7:00–8:00 AM
Skeletal Muscle, Renal, and Vascular Crosstalk and CV Disease
8:00–11:00 AM
Zoltan Arany, University of Pennsylvania
Rerouting Metabolic Fuel Flux Utilization across Organs in Cardiometabolic Disease
Flora Sam †, Eli Lilly
Skeletal Muscle Myokines and HFpEF
Kristin I. Stanford, Ohio State University
Exercise, Adipose & Metabolic Crosstalk
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
Panel Discussion: AI Tools in Cardiometabolic Research
11:00–12:00 PM
Poster Setup
12:00–1:00 PM
On Own for Lunch
12:00–5:00 PM
Poster Viewing
1:00–10:00 PM
Career Roundtable
3:00–4:30 PM
Coffee Available
4:30–5:00 PM
Immune System Crosstalk in Cardiovascular and Metabolic Disease
5:00–7:00 PM
Kory J. Lavine, Washington University School of Medicine
Single Cell Epigenomics to Reveal Cellular Crosstalk in CV Disease
Diane Mathis †, Harvard Medical School
Immune Modulation of Skeletal Muscle Function and Exercise Adaptation
Speaker to be Announced
Han Zhu, Stanford University
T Lymphocyte Subsets in Cardiovascular Homeostasis and Response to Cancer Immunotherapy
Short Talk(s) Chosen from Abstracts
Social Hour with Dinner
7:00–8:00 PM
Posters
7:30–10:00 PM
Thursday, February 18, 2027
Breakfast
7:00–8:00 AM
Emerging Cardiometabolic Therapeutics
8:00–11:00 AM
William A. Chutkow †, Novartis Institute for Biomedical Research
Targeting Lean Muscle Mass in Cardiovascular and Metabolic Disease
Ambarish Pandey, UT Southwestern Medical Center
Heterogeneity in the Cardiovascular Benefits of GLP-1R Agonists: Identifying Treatment Responders Leveraging Novel Phenotyping and Data Science Approach
Speaker to be Announced
Novel Nucleic Acid-based Therapeutic Platforms in Cardiovascular and Metabolic Disease
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
Poster Setup
11:00–1:00 PM
On Own for Lunch
11:00–5:00 PM
Poster Viewing
11:00–10:00 PM
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Nervous System Crosstalk in Cardiometabolic Disease
5:00–7:00 PM
Speaker to be Announced
Daniela Carnevale †, University La Sapienza in Rome
Heart-Brain-Splenic Axis and Control of Heart Failure and Hypertension
Filip K. Swirski, Icahn School of Medicine at Mount Sinai
Novel Immune/Neural Mechanisms in Cardiometabolic Disease
Clemence Blouet †, University of Cambridge
Central Mechanisms Underlying Synergistic Effects of Weight Loss Drugs
Short Talk(s) Chosen from Abstracts
Social Hour with Dinner
7:00–8:00 PM
Posters
7:30–10:00 PM
Friday, February 19, 2027
Breakfast
7:00–8:00 PM
Adiposity, Diabetes and Clinical CV Disease
8:00–11:00 PM
David A Kass, Johns Hopkins Hospital
Obesity + HFpEF = Bad Sarcomeres
Karol E. Watson, University of California, Los Angeles
Novel Insights from the DPPOS Cohort
Saptarsi M. Haldar
Novel Approaches to Treating Obesity and Adiposity-Related Diseases
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 PM
On Own for Lunch
11:00–5:00 PM
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Novel Mechanisms of Liver, Adipose and Cardiovascular Crosstalk
5:30–6:45 PM
Isha Jain, Arc Institute and Gladstone/UCSF
Hypoxic Signaling and Interorgan Crosstalk in Physiology & Disease
E. Dale Abel †, David Geffen School of Medicine and UCLA Health
Insulin Signaling, Mitochondria and Metabolic Heart Disease
Katrin J. Svensson, Stanford University
Novel Peptides as Obesity Therapeutic Targets
Gabriele G Schiattarella, Charité University Medical Center
Cardiometabolic-Hepatic Crosstalk
Short Talk(s) Chosen from Abstracts
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Social Hour with Dinner
7:00–8:00 PM
Cash Bar
8:00–11:00 PM
Entertainment
8:00–11:00 PM
Saturday, February 20, 2027
Departure
12:00–11:59 PM

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