Transposable Elements: From Evolution to Engineering

Mar 15–18, 2027 | Beaver Run Conference Center, Breckenridge, CO, United States
Scientific Organizers: Irina Arkhipova, Samuel H Sternberg, Ting Wang, and Phillip D. Zamore

  In Person
  On Demand
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Mar 15–18, 2027 | Beaver Run Conference Center, Breckenridge, CO, United States

Scientific Organizers: Irina Arkhipova, Samuel H Sternberg, Ting Wang, and Phillip D. Zamore

Supported by the  Directors' Fund

***Meeting program subject to change.

Available Formats:   = In Person     = On Demand
Monday, March 15, 2027
Registration
4:00–8:00 PM
Welcome Mixer
6:00–8:00 PM
Tuesday, March 16, 2027
Breakfast
7:00–8:00 AM
Welcome and Keynote Address
8:00–9:00 AM
Vera Gorbunova, University of Rochester
Role of L1 Retrotransposons in Aging
Structural and Mechanistic Aspects of Transposition
9:00–11:15 AM
Samuel H Sternberg, Columbia University
Functional Roles of Domesticated Reverse Transcriptases in Antiviral Immunity
George E. Ghanim, Princeton University
Structure and Biochemistry of L1 and Alu Retrotransposition
Elizabeth Kellogg, St. Jude Children's Research Hospital
Structures of the Holo CRISPR RNA-Guided Transposon Integration Complex
Short Talk(s) Chosen from Abstracts
Coffee Break
9:30–9:50 AM
Meet the Editors
11:15–12:15 PM
Poster Setup
11:15–1:00 PM
On Own for Lunch
11:15–5:00 PM
Poster Viewing
1:00–10:00 PM
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Transposons in Genome Editing and Engineering
5:00–7:00 PM
R. K Slotkin, Donald Danforth Plant Science Center
The Control of Transposable Elements in Plants
Jonathan S. Gootenberg †, Harvard Medical School
Reprogramming Site-Specific Retrotransposon Activity to New DNA Sites
Akanksha Thawani †, Columbia University
Structures of Vertebrate R2 Retrotransposon Complexes during Target-Primed Reverse Transcription
Short Talk(s) Chosen from Abstracts
Social Hour with Dinner
7:00–8:00 PM
Posters
7:30–10:00 PM
Wednesday, March 17, 2027
Breakfast
7:00–8:00 AM
Transposons in Disease and Therapeutics
8:00–11:00 AM
Ting Wang, Washington University
Transposable Elements and Cancer Epigenome
Heike Keilhack †, ROME Therapeutics
Drug Discovery in the Dark Genome
Hui Shen †, Van Andel Institute
Probing Transposable Element Expression in Single Cells
Katherine Chiappinelli, George Washington University
The Viral Mimicry Response to Transposable Elements in Cancer
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
Poster Setup
11:00–1:00 PM
On Own for Lunch
11:00–5:00 PM
Poster Viewing
1:00–10:00 PM
Career Roundtable
3:00–4:30 PM
Coffee Available
4:30–5:00 PM
Evolution and Genomics
5:00–7:00 PM
Irina Arkhipova, Marine Biological Laboratory
Evolution of Reverse Transcription Mechanisms
George Kassiotis, The Francis Crick Institute
HERVs and Evolution of Host Immunity
Oleg Simakov †, University of Vienna
Transposable Elements and Evolution of Metazoan Genome Architecture
Short Talk(s) Chosen from Abstracts
Social Hour with Dinner
7:00–8:00 PM
Posters
7:30–10:00 PM
Thursday, March 18, 2027
Breakfast
7:00–8:00 AM
Small RNAs and Transposon Silencing
8:00–11:00 AM
Phillip D. Zamore, University of Massachusetts Chan Medical School
How are Pachytene piRNAs Made and What Do They Do?
Yukiko M. Yamashita, Whitehead Institute
Silencing of Transposons in rDNA and of Selfish Genetic Elements in the Male Germ Line in Flies
René F. Ketting, Institute for Molecular Biology
Transposon Control by Small RNAs in Nematodes
Ansgar Zoch, University of Edinburgh
RNA-Directed Epigenetic Silencing of Transposons in the Mammalian Male Germline
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–5:00 PM
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Transposon-Host Interactions
5:00–7:00 PM
Deborah Bourc'his †, Institut Curie
Epigenetic Decisions and Reproduction in Mammals
Julius Brennecke †, IMBA - Institut für Molekulare Biotechnologie GmbH
Transposons, piRNAs and Drosophila Oogenesis
Vincent Colot †, École Normale Supérieure
Genetic and Epigenetic Variation and Environmental Adaptation in Arabidopsis
Short Talk(s) Chosen from Abstracts
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Social Hour with Dinner
7:00–8:00 PM
Entertainment
8:00–11:00 PM
Cash Bar
8:00–11:00 PM
Friday, March 19, 2027
Departure
12:00–11:59 PM

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