Tumor Metabolism: Novel Pathways and Therapeutic Challenges

Mar 05–09, 2028 | Keystone Resort, Keystone, CO, United States
Scientific Organizers: Matthew G Vander Heiden, Daniel E. Frigo, and Lydia Finley

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Mar 05–09, 2028 | Keystone Resort, Keystone, CO, United States

Scientific Organizers: Matthew G Vander Heiden, Daniel E. Frigo, and Lydia Finley

Supported by:  

***Meeting program subject to change.

Available Formats:     = Livestream   = In Person     = On Demand
Monday, March 6, 2028
Registration
1:00–6:00 PM
Welcome Remarks
3:00–3:10 PM
Keynote Address
3:10–4:00 PM
Ralph J DeBerardinis, University of Texas Southwestern Medical Center
Cancer as a Systemic Metabolic Disease
Metabolites as Signaling Molecules to Influence Cancer
4:00–6:00 PM
Kathryn E. Wellen, University of Pennsylvania
How Environmental Metabolite Availability Shapes Gene Regulation
Navdeep S Chandel †, Northwestern University
Systemic Impact of Metabolites
Lydia Finley, Memorial Sloan Kettering Cancer Center
Decoding Metabolic Signals during Cell Fate Transitions
Short Talk(s) Chosen from Abstracts
Welcome Reception
6:00–8:00 PM
Tuesday, March 7, 2028
Poster Setup
12:25–1:00 PM
Breakfast
7:00–8:00 AM
New Insights into Metabolic Pathways
8:00–11:15 AM
Gina M DeNicola, Moffitt Cancer Center
Impact of Tumor Microenvironment Nutrient Availability on Tumor Redox State
Arkaitz Carracedo †, Center for Cooperative Research in Biosciences
Emerging Intersections between Metabolism and Signaling
Lucas B. Sullivan, Fred Hutchinson Cancer Research Center
Novel Mass Spectrometry Methods to Study Cysteine Metabolism and the Impact on Drug Response
Gerta Hoxhaj, UT Southwestern Medical Center
Novel Regulation of Cancer Cell Metabolism
Short Talk(s) Chosen from Abstracts
Coffee Break
9:30–9:50 AM
Meet-the-Editor
11:25–12:25 PM
On Own for Lunch
12:25–5:00 PM
Poster Viewing
1:00–10:00 PM
Symposia Spotlight 1: Systemic Metabolism
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Altered Organellar Metabolism in Cancer
5:00–7:00 PM
Payam Anthony Gammage, Cancer Research UK Scotland Institute
Mitochondrial DNA Mutation and Tumorigenesis
Kivanc Birsoy, Rockefeller University
Approaches to Study Organelle Metabolite Transport
Jared Rutter, University of Utah
Pathway Regulation by Organellar Metabolites
Short Talk(s) Chosen from Abstracts
Social Hour with Dinner
7:00–8:00 PM
Posters
7:30–10:00 PM
Wednesday, March 8, 2028
Breakfast
7:00–8:00 AM
Impact of the Microenvironment on Tumor Metabolism
8:00–11:00 AM
Alexander Muir †, University of Chicago
Influence of Environmental Metabolites on Cancer Phenotypes
Sarah-Maria Fendt, VIB-KU Leuven
Local and Systemic Metabolic Influences on Metastasis
Wilhelm Palm, German Cancer Reserach Center
Microenvironmental Control of Cancer Metabolism
Jessalyn M. Ubellacker, Harvard T.H. Chan School of Public Health
Ferroptosis and the Metastatic Microenvironment
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
Poster Setup
11:00–1:00 PM
On Own for Lunch
11:00–5:00 PM
Poster Viewing
1:00–10:00 PM
Career Roundtable
3:00–4:30 PM
Coffee Available
4:30–5:00 PM
Metabolic Drivers of Tumor Evolution
5:00–7:00 PM
Maria Rodriguez Colman †, UMC Utrecht
Use of Metabolite Sensors to Assess Redox Regulation of Cancer Phenotypes
Christian Frezza †, University of Cologne
From Genotype to Metabolic Phenotype: Multi-Omic Approaches to Cancer Evolution
Matthew G Vander Heiden, Massachusetts Institute of Technology
Impact of Metabolism on Cancer Heterogeneity
Short Talk(s) Chosen from Abstracts
Social Hour with Dinner
7:00–8:00 PM
Posters
7:30–10:00 PM
Thursday, March 9, 2028
Breakfast
7:00–8:00 AM
Intersections between Tumor and Host
8:00–11:00 AM
Rachel J. Perry †, Yale University
How Host Metabolism Shapes Tumor Metabolism
Liza Makowski †, The Ohio State University
Impact of Surgical and Pharmacological Weight Loss on Cancer
Speaker to be Announced
Thales Papagiannakopoulos †, Salk Institute for Biological Studies
How Cancer-Nerve Interactions Influence Host Metabolism
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–5:00 PM
Symposia Spotlight 2
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Metabolic Considerations for Successful Cancer Therapy
5:00–6:45 PM
Daniel E. Frigo, University of Texas MD Anderson Cancer Center
Targeting Prostate Cancer Metabolism Across Shifting Endocrine States
Costas A. Lyssiotis †, University of Michigan
Treating Cancer by Targeting Salvage Metabolism
Karen H. Vousden, Francis Crick Institute
Systemic Metabolic Approaches to Target Cancer
Short Talk(s) Chosen from Abstracts
Meeting Wrap-Up: Outcomes and Future Directions
6:45–7:00 PM
Social Hour with Dinner
7:00–8:00 PM
Entertainment
8:00–11:00 PM
Cash Bar
8:00–11:00 PM
Friday, March 10, 2028
Departure
12:00–11:59 PM

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