Neurobiology of Ingestive Behavior
Apr 22–25, 2025 | Asilomar Hotel and Conference Grounds, Pacific Grove, CA, United States
Scientific Organizers:
Daniela Cota, Timo D. Müller, and Dana M. Small
In Person
On Demand
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Apr 22–25, 2025 | Asilomar Hotel and Conference Grounds, Pacific Grove, CA, United States
Scientific Organizers: Daniela Cota, Timo D. Müller, and Dana M. Small
Daniela Cota
Timo D. Müller
Dana M. Small
Available Formats:
Supported by:
In Person
On Demand
***Meeting program subject to change.
Available Formats: = In Person = On DemandTuesday, April 22, 2025
Fundraising
Booking Function
Merchandise Options
Registration Options
Registration
4:00–8:00 PM
Chapel
Dinner
6:00–7:00 PM
Crocker Dining Room
Welcome Mixer and Social Hour
7:00–8:00 PM
Chapel
Wednesday, April 23, 2025
Breakfast
7:30–8:30 AM
Crocker Dining Room
Welcome and Keynote Address
8:30–9:30 AM
Chapel
* Daniela Cota, INSERM U1215 Neurocentre Magendie
* Timo D. Müller, Institute for Diabetes and Obesity, Helmholtz Munich
* Dana M. Small, McGill University and the Research Institute of the McGill University Health Center (RI-MUHC)
Matthias H. Tschöp, Helmholtz Munich
Multi-Receptor Drugs for Obesity: Discovery, Mechanism & Clinical Impact
Multi-Receptor Drugs for Obesity: Discovery, Mechanism & Clinical Impact
CNS Mechanisms of Novel Therapies Against Obesity and Beyond
9:30–12:00 PM
Chapel
* Daniela Cota, INSERM U1215 Neurocentre Magendie
Session Chair
Session Chair
Timo D. Müller, Institute for Diabetes and Obesity, Helmholtz Munich
A Novel Incretin-based Quintuple Agonist for the Treatment of Obesity and Diabetes
A Novel Incretin-based Quintuple Agonist for the Treatment of Obesity and Diabetes
Julie Moyers, Eli Lilly and Company
Novel Drugs Targeting CNS Mechanisms of Body Weight Loss: The Oral GLP-1R Agonist, Orforglipron
Novel Drugs Targeting CNS Mechanisms of Body Weight Loss: The Oral GLP-1R Agonist, Orforglipron
Karin Conde-Knape, Novo Nordisk A/S
CNS Mechanisms of Cagrilintide-Semaglutide Combinatorial Therapy to Treat Obesity
CNS Mechanisms of Cagrilintide-Semaglutide Combinatorial Therapy to Treat Obesity
Mafalda M.A. Pereira, Boehringer Ingelheim
Deciphering the Mechanisms of Survodutide as an Anti-Obesity Therapy
Deciphering the Mechanisms of Survodutide as an Anti-Obesity Therapy
Coffee Break
10:00–10:20 AM
Chapel
Poster Setup
12:00–1:00 PM
Chapel
Lunch
12:00–1:00 PM
Crocker Dining Room
Poster Viewing
12:30–1:30 PM
Chapel
Symposia Spotlight 1: Research presentations selected from abstract submissions
1:30–3:30 PM
Chapel
* Robyn M. Brown, University of Melbourne
Session Chair
Session Chair
Tim Gruber, Van Andel Institute
Binge-Eating Disorder Vulnerability Is Determined By Tet1 Dosage In Midbrain Dopamine Neurons
Binge-Eating Disorder Vulnerability Is Determined By Tet1 Dosage In Midbrain Dopamine Neurons
Giulia Mazzini, University of Zurich
From Metabolism To Memory: Exploring Amylin's Physiological Role In The Hippocampus
From Metabolism To Memory: Exploring Amylin's Physiological Role In The Hippocampus
Leontine Sandforth, Institute for Diabetes Research and Metabolic Diseases, Tübingen, Germany
Hippocampal Response To Central Insulin Is Reduced With Age In Females With Unhealthy Fat Distribution
Hippocampal Response To Central Insulin Is Reduced With Age In Females With Unhealthy Fat Distribution
Emily McGrath, UCSF
Apolipoprotein E Regulates Microglial Remodeling Of Hypothalamic Myelin In Obesity
Apolipoprotein E Regulates Microglial Remodeling Of Hypothalamic Myelin In Obesity
Xinyu Yue, University of California, San Francisco
Molecular Representation Of Peripheral Energy Levels By Neuronal Cilia
Molecular Representation Of Peripheral Energy Levels By Neuronal Cilia
Moonsun Sa, Seoul national university
Role Of Hypothalamic Gabra5 Neurons And Astrocytic Gaba In Fat Regulation And Obesity
Role Of Hypothalamic Gabra5 Neurons And Astrocytic Gaba In Fat Regulation And Obesity
Hallie Wachsmuth, University of Arizona
Mediobasal Hypothalamic Aryl Hydrocarbon Receptor Is Critical For Metabolic Homeostasis Via Regulation Of Hypothalamic Inflammation
Mediobasal Hypothalamic Aryl Hydrocarbon Receptor Is Critical For Metabolic Homeostasis Via Regulation Of Hypothalamic Inflammation
Madina Sokolov, University of Michigan
Defining The Gut-Pancreas Neuronal Circuit That Controls Insulin Secretion
Defining The Gut-Pancreas Neuronal Circuit That Controls Insulin Secretion
Coffee Available
3:30–4:00 PM
Chapel
Gut-Brain Axis and Feeding Behavior
4:00–6:00 PM
Chapel
* Dana M. Small, McGill University and the Research Institute of the McGill University Health Center (RI-MUHC)
Session Chair
Session Chair
Zachary A. Knight, University of California, San Francisco
Learning from Post-Ingestive Rewards
Learning from Post-Ingestive Rewards
Ivan E. de Araujo, Max Planck Institute for Biological Cybernetics
The Gut-Brain Axis in Feeding Behavior
The Gut-Brain Axis in Feeding Behavior
Martin G. Myers, Jr., University of Michigan
Hindbrain Circuits in the Control of Eating Behavior and Energy Balance
Hindbrain Circuits in the Control of Eating Behavior and Energy Balance
Nicholas V DiPatrizio, University of California Riverside School of Medicine, Center for Cannabinoid Research
Short Talk: The Ups And Downs Of Brain-Gut-Brain Endocannabinoid Signaling In Food Intake And Reward
Short Talk: The Ups And Downs Of Brain-Gut-Brain Endocannabinoid Signaling In Food Intake And Reward
Nikolai Pirmin P Jaschke, Yale School of Medicine
Short Talk: Gut-To-Brain Communication Protects Against Dietary Protein Toxicity During Recovery From Catabolic States
Short Talk: Gut-To-Brain Communication Protects Against Dietary Protein Toxicity During Recovery From Catabolic States
Dinner
6:00–7:00 PM
Crocker Dining Room
Poster Session 1
7:00–9:00 PM
Chapel
Thursday, April 24, 2025
Breakfast
7:30–8:30 AM
Crocker Dining Room
Neuronal Circuits Integrating Hunger and Other Competing States
8:30–11:30 AM
Chapel
* Matthew R. Hayes, University of Pennsylvania
Session Chair
Session Chair
Marc Tittgemeyer, Max Planck Institute for Metabolism Research
Need State Regulation of Motivational Drive
Need State Regulation of Motivational Drive
Hyung Jin Choi, Seoul National University College of Medicine
Neural Circuits Integrating Hunger and Food Choices
Neural Circuits Integrating Hunger and Food Choices
Robyn M. Brown, University of Melbourne
Neural Circuits Underlying Stress-Related Eating
Neural Circuits Underlying Stress-Related Eating
Heidi H Pak, UT Southwestern
Short Talk: Habitual Feeding Schedule Enhances The Metabolic And Physiological Effects Of Calorie Restriction
Short Talk: Habitual Feeding Schedule Enhances The Metabolic And Physiological Effects Of Calorie Restriction
Tanya Pattnaik, University of Illinois, Urbana-Champaign
Short Talk: Dopamine Signaling Regulates Feeding Behavior During Lactation In Mice
Short Talk: Dopamine Signaling Regulates Feeding Behavior During Lactation In Mice
Elijah D Lowenstein, Beth Israel Deaconess Medical Center
Short Talk: A Hypothalamic Circuit For Anticipating Future Changes In Energy Balance
Short Talk: A Hypothalamic Circuit For Anticipating Future Changes In Energy Balance
Yael Kuperman, Weizmann Institute
Short Talk: Disruption Of The Developmental Factor Otp In The Adult Forebrain Reveals Its Diverse Physiological Functions
Short Talk: Disruption Of The Developmental Factor Otp In The Adult Forebrain Reveals Its Diverse Physiological Functions
Coffee Break
9:30–9:50 AM
Chapel
Award Recipient Acknowledgement
9:50–9:55 AM
Chapel
Lunch
12:00–1:00 PM
Crocker Dining Room
Poster Setup
12:00–1:00 PM
Chapel
Career Roundtable
1:00–2:00 PM
Chapel
Karin Conde-Knape, Novo Nordisk A/S
Senior Vice President, Global Drug Discovery
Senior Vice President, Global Drug Discovery
Laura Huckins, Yale School of Medicine
Associate Professor
Associate Professor
Marc Tittgemeyer, Max Planck Institute for Metabolism Research
Professor, Research Group Leader
Professor, Research Group Leader
Jonathan D Douros, Indiana Biosciences Research Institute
Senior Scientific Director
Senior Scientific Director
Poster Viewing
1:00–2:30 PM
Chapel
Panel Discussion: How to Fill the Gap between Academic Research and Clinical Implementation? Addressing Reproducibility, Research Standards and Translation Towards the Clinic
2:00–3:45 PM
Chapel
* Daniela Cota, INSERM U1215 Neurocentre Magendie
Session Chair
Session Chair
* Timo D. Müller, Institute for Diabetes and Obesity, Helmholtz Munich
Session Chair
Session Chair
Matthias H. Tschöp, Helmholtz Munich
Panelist
Panelist
Dana M. Small, McGill University and the Research Institute of the McGill University Health Center (RI-MUHC)
Panelist
Panelist
Brian Finan, Eli Lilly
Panelist
Panelist
Monika Murphy, Kallyope
Panelist
Panelist
Martin G. Myers, Jr., University of Michigan
Panelist
Panelist
Stephen O'Rahilly, University of Cambridge
Panelist
Panelist
Coffee Available
3:45–4:00 PM
Chapel
Aversive and Non-Aversive Circuits of Appetite Suppression
4:00–6:00 PM
Chapel
* Thomas Alexander Lutz, University of Zürich
Session Chair
Session Chair
Matthew R. Hayes, University of Pennsylvania
GIP and GLP-1 Signaling in Satiety and Nausea
GIP and GLP-1 Signaling in Satiety and Nausea
Stephen O'Rahilly, University of Cambridge
GDF15 in Nausea and Beyond
GDF15 in Nausea and Beyond
Laura Huckins, Yale School of Medicine
Genetic and Biological Determinants of Anorexia Nervosa
Genetic and Biological Determinants of Anorexia Nervosa
Stephan Herzig, Helmholtz Zentrum München
Cancer Cachexia: Bridging the CNS with Peripheral Wasting
Cancer Cachexia: Bridging the CNS with Peripheral Wasting
Dinner
6:00–7:00 PM
Crocker Dining Room
Poster Session 2
7:00–9:00 PM
Chapel
Friday, April 25, 2025
Breakfast
7:30–8:30 AM
Crocker Dining Room
Neuroendocrine Control of Food Intake, Body Weight and Metabolism
8:30–11:30 AM
Chapel
* Martin G. Myers, Jr., University of Michigan
Session Chair
Session Chair
Karine Clément, INSERM / Sorbonne Universite
REMOTE PRESENTER: Precision Medicine Approach in Patients with Melanocortin Pathway Disorders
REMOTE PRESENTER: Precision Medicine Approach in Patients with Melanocortin Pathway Disorders
Daniela Cota, INSERM U1215 Neurocentre Magendie
Hypothalamic Responses to Energy Surfeit in the Regulation of Energy Balance
Hypothalamic Responses to Energy Surfeit in the Regulation of Energy Balance
Thomas Alexander Lutz, University of Zürich
Brain Circuits for Amylin Action
Brain Circuits for Amylin Action
Elizabeth Godschall, University of Virginia
Short Talk: A Brain Reward Circuit Inhibited By Next-Generation Weight Loss Drugs
Short Talk: A Brain Reward Circuit Inhibited By Next-Generation Weight Loss Drugs
Shuke Xiao, Stanford University
Short Talk: A Postprandial Python Metabolite Mediates A Gut-Liver-Brain Feeding Axis
Short Talk: A Postprandial Python Metabolite Mediates A Gut-Liver-Brain Feeding Axis
Mireia Montaner, University of Cambridge
Short Talk: Interactions Between Olfactory Bulb Glp-1, Sensory Perception Of Food And Feeding Behaviour
Short Talk: Interactions Between Olfactory Bulb Glp-1, Sensory Perception Of Food And Feeding Behaviour
Zhenggang Zhu, UC San Diego
Short Talk: Hedonic Eating Is Controlled By Dopamine Neurons That Oppose Glp-1r Satiety
Short Talk: Hedonic Eating Is Controlled By Dopamine Neurons That Oppose Glp-1r Satiety
Coffee Break
9:30–9:50 AM
Chapel
Lunch
12:00–1:00 PM
Crocker Dining Room
Poster Setup
12:00–1:00 PM
Chapel
Poster Viewing
12:30–1:30 PM
Chapel
Symposia Spotlight 2: Research presentations selected from abstract submissions
1:30–3:30 PM
Chapel
* Laura Huckins, Yale School of Medicine
Session Chair
Session Chair
Robert M Gutgesell, Helmholtz Center Munich
Gipr Agonism and Antagonism Decrease Body Weight and Food Intake Via Different Mechanisms of Action
Gipr Agonism and Antagonism Decrease Body Weight and Food Intake Via Different Mechanisms of Action
Caitlin M Baumer Harrison, University of Pennsylvania
Biased Agonism Of The Glp-1r Maintains Glycemic Control Without Producing Nausea Or Emesis In Preclinical Models
Biased Agonism Of The Glp-1r Maintains Glycemic Control Without Producing Nausea Or Emesis In Preclinical Models
Antje Körner, Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) at Helmholtz Munich and Leipzig University
A Novel Monogenic Agouti-Like Obesity Trait: New Insights From Mice And Men
A Novel Monogenic Agouti-Like Obesity Trait: New Insights From Mice And Men
Mette Ludwig, Novo Nordisk
Cross-Species Atlas Of The Dorsal Vagal Complex Reveals Neural Mediators Of Cagrilintide’s Effects On Energy Balance
Cross-Species Atlas Of The Dorsal Vagal Complex Reveals Neural Mediators Of Cagrilintide’s Effects On Energy Balance
Jo E Lewis, University of Cambridge
Glucose-Dependent Insulinotrophic Polypeptide Regulates Food Intake And Body Weight Via The Area Postrema In Mice
Glucose-Dependent Insulinotrophic Polypeptide Regulates Food Intake And Body Weight Via The Area Postrema In Mice
Samantha Fortin, University of Pennsylvania
Regulation Of Food Intake By The Locus Coeruleus
Regulation Of Food Intake By The Locus Coeruleus
Han Tan, Rockefeller University
The Cellular And Molecular Basis For Leptin Regulation Of Energy Balance
The Cellular And Molecular Basis For Leptin Regulation Of Energy Balance
Abbey Blake, UCSF
A New Crispri Approach To Investigate The Pathogenic Mechanism Of Obesity-Associated Genes
A New Crispri Approach To Investigate The Pathogenic Mechanism Of Obesity-Associated Genes
Coffee Available
3:30–4:00 PM
Chapel
Neural Substrates of Hedonic Eating and Decision Making
4:00–5:45 PM
Chapel
* Ivan E. de Araujo, Max Planck Institute for Biological Cybernetics
Session Chair
Session Chair
Christian Lüscher, University of Geneva
Circuits of Hedonic Feeding in Health and Disease
Circuits of Hedonic Feeding in Health and Disease
Dana M. Small, McGill University and the Research Institute of the McGill University Health Center (RI-MUHC)
Sugar and Fat: Distinct Reinforcement Mechanisms and Adaptations in Obesity
Sugar and Fat: Distinct Reinforcement Mechanisms and Adaptations in Obesity
Soyoung Q. Park, German Institute of Human Nutrition Potsdam-Rehbruecke
Neural Determinants of Decision Making in Feeding Behavior
Neural Determinants of Decision Making in Feeding Behavior
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
5:45–6:00 PM
Chapel
Dinner
6:00–7:00 PM
Crocker Dining Room
Poster Session 3
7:00–9:00 PM
Chapel
Saturday, April 26, 2025
Breakfast
7:30–9:00 AM
Crocker Dining Room
Lunch
12:00–1:00 PM
Crocker Dining Room
Departure
1:00–11:59 PM
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