Joint with: Cardiometabolism in Health and Disease
Obesity Therapeutics: Unlocking Benefits and Minimizing Side Effects
Jan 26–29, 2026 | Keystone Resort, Keystone, CO, United States
Scientific Organizers:
Lora K. Heisler, James Trevaskis, Michael A Cowley and Matthias H. Tschöp
Jan 26–29, 2026 | Keystone Resort, Keystone, CO, United States
Scientific Organizers:
Lora K. Heisler, James Trevaskis, Michael A Cowley and Matthias H. Tschöp
Available Formats:
Supported by the Directors' Fund
Livestream
In Person
On Demand
***Meeting program subject to change.
Available Formats: = Livestream = In Person = On DemandMonday, January 26, 2026
Fundraising
Booking Function
Merchandise Options
Registration Options
Registration
4:00–8:00 PM
Welcome Mixer
6:00–8:00 PM
Tuesday, January 27, 2026
Breakfast
7:00–8:00 AM
Welcome and Keynote Address (Joint)
8:00–9:00 AM
Richard D DiMarchi, Indiana University
The Chemical Evolution of Peptides To Transform Human Health
The Chemical Evolution of Peptides To Transform Human Health
Beyond Weight Loss: New Directions for Obesity Therapeutics (Joint)
9:00–11:15 AM
Rachel J. Roth Flach, Pfizer Inc.
Targeting Metabolism for HFpEF
Targeting Metabolism for HFpEF
Susan Quaggin, Northwestern University
A United Vision for Kidney and Cardiovascular Disease Treatment
A United Vision for Kidney and Cardiovascular Disease Treatment
James Trevaskis, Eli Lilly
Incretins for MASH Treatment
Incretins for MASH Treatment
Short Talk(s) Chosen from Abstracts
Coffee Break
9:30–9:50 AM
Meet the Editors (Joint)
11:15–12:15 PM
* Rong Tian, University of Washington
Poster Setup
11:15–1:00 PM
On Own for Lunch
11:15–2:30 PM
Poster Viewing
1:00–10:00 PM
Symposia Spotlight 1: Emerging Therapies, Lifestyle Interventions and AI Approaches (Joint)
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Late Breaking Research on Obesity Development
5:00–7:00 PM
Ana Paula Arruda, University of California, Berkeley
Metabolic Adaptations to Nutritional Fluctuations
Metabolic Adaptations to Nutritional Fluctuations
Jason Gill, University of Glasgow
Ethnic Differences in the Development and Management of Obesity
Ethnic Differences in the Development and Management of Obesity
Randy J. Seeley, University of Michigan
Body Weight Set Point
Body Weight Set Point
Short Talk(s) Chosen from Abstracts
Social Hour with Lite Bites
7:00–8:00 PM
Posters
7:30–10:00 PM
Wednesday, January 28, 2026
Breakfast
7:00–8:00 AM
CNS Mechanisms of Action of Weight Loss
8:00–11:00 AM
Michael A Cowley, Monash University
Hypothalamic Neurocircuits that Mediate Drug Actions
Hypothalamic Neurocircuits that Mediate Drug Actions
Lora K. Heisler, Rowett Institute, University of Aberdeen
Brain GPCR Targets and Circuits Controlling Food Intake
Brain GPCR Targets and Circuits Controlling Food Intake
Bei B. Zhang, Novo Nordisk
Modulation of GLP-1 and Amylin Receptors for Weight Management
Modulation of GLP-1 and Amylin Receptors for Weight Management
Giuseppe D'Agostino, University of Manchester
Appetite and Body Weight Control via Caudal Brainstem Circuits
Appetite and Body Weight Control via Caudal Brainstem Circuits
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
Poster Setup
11:00–1:00 PM
On Own for Lunch
11:00–1:30 PM
Poster Viewing
1:00–10:00 PM
Career Roundtable (Joint)
1:30–2:45 PM
Coffee Available
4:30–5:00 PM
Leveraging Enteroendocrine Cell Secretion
5:00–7:00 PM
Shirly Pinto, Kallyope
Unlocking GLP-1 Expressing Cells for Novel Therapeutics
Unlocking GLP-1 Expressing Cells for Novel Therapeutics
Fiona M. Gribble, University of Cambridge
Mechanisms Underlying Nutrient Sensing in Human Intestinal-Secreting Cells
Mechanisms Underlying Nutrient Sensing in Human Intestinal-Secreting Cells
Kevin G. Murphy, Imperial College London
Dietary Drivers of Gut Hormone Release
Dietary Drivers of Gut Hormone Release
Short Talk(s) Chosen from Abstracts
Social Hour with Lite Bites
7:00–8:00 PM
Posters
7:30–10:00 PM
Thursday, January 29, 2026
Breakfast
7:00–8:00 AM
Emerging Therapies for Obesity and Cardiometabolic Diseases (Joint)
8:00–11:00 AM
Matthias H. Tschöp, Helmholtz Munich
Dual and Triple Co-Agonists: From Discovery to Best-in-Class
Dual and Triple Co-Agonists: From Discovery to Best-in-Class
Kirsten Raun, Novo Nordisk A/S
Amylin: The All-Inclusive Obesity Therapeutic
Amylin: The All-Inclusive Obesity Therapeutic
Thomas Alexander Lutz, University of Zürich
Amylin Physiology and its Therapeutic Potential to Treat Metabolic Diseases
Amylin Physiology and its Therapeutic Potential to Treat Metabolic Diseases
Murielle M Véniant-Ellison, Amgen Inc.
Unlocking the Power of GIPR and GLP-1R Targeting for Effective Weight Loss and Metabolic Improvement
Unlocking the Power of GIPR and GLP-1R Targeting for Effective Weight Loss and Metabolic Improvement
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–2:30 PM
Symposia Spotlight 2: Leveraging Genetics
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Preservation of Muscle Mass and Function during Weight Loss
5:00–6:45 PM
Mark W. Sleeman, Regeneron Pharmaceuticals
Strategies to Prevent Muscle Loss
Strategies to Prevent Muscle Loss
Philip Larsen, Sixpeaks Bio AG
Preservation of Skeletal Muscle is a Key to Healthy Weight Loss
Preservation of Skeletal Muscle is a Key to Healthy Weight Loss
Ffolliott M Fisher, Keros Therapeutics
Targeting the TGF-β super Family for the Preservation of Muscle Mass and Weight Loss
Targeting the TGF-β super Family for the Preservation of Muscle Mass and Weight Loss
Short Talk(s) Chosen from Abstracts
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Social Hour with Lite Bites
7:00–8:00 PM
Cash Bar
8:00–11:00 PM
Entertainment
8:00–11:00 PM
Friday, January 30, 2026
Departure
12:00–11:59 PM
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