Joint with: Neural Plasticity and Recovery after Traumatic CNS Injury & Stroke
Neurodevelopmental Disorders: Mechanisms and Therapeutics

Jan 19–22, 2027 | Beaver Run Conference Center, Breckenridge, CO, United States
Scientific Organizers: Tomasz Nowakowski, Xin Jin, Stephan Sanders, and Zhaolan (Joe) Zhou

  In Person
  On Demand
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Jan 19–22, 2027 | Beaver Run Conference Center, Breckenridge, CO, United States

Scientific Organizers: Tomasz Nowakowski, Xin Jin, Stephan Sanders, and Zhaolan (Joe) Zhou

Supported by the  Directors' Fund

***Meeting program subject to change.

Available Formats:   = In Person     = On Demand
Tuesday, January 19, 2027
Registration
4:00–8:00 PM
Welcome Mixer
6:00–8:00 PM
Wednesday, January 20, 2027
Breakfast
7:00–8:00 AM
Welcome and Keynote Address
8:00–9:00 AM
Huda Y. Zoghbi †, Baylor College of Medicine
A Journey in Rett Syndrome: From Basic Science Discovery of Causal Gene to Therapies of Patients
Genetics and Genomics of Neurodevelopmental Disorders
9:00–11:15 AM
Hyejung Won, University of North Carolina, Chapel Hill
Experimental Validation of Common Variants of Neurodevelopmental Disorders
Xin Jin, Scripps Research Institute
Massively Parallel Dissection of Gene to Phenotype Relationships using Perturb-seq
Thomas Bourgeron †, Institut Pasteur
PARIS: Paris Autism Research International Sib-Pair Study
Short Talk(s) Chosen from Abstracts
Coffee Break
9:30–9:50 AM
Meet the Editors
11:15–12:15 PM
Poster Setup
12:15–1:00 PM
On Own for Lunch
12:15–5:00 PM
Poster Viewing
1:00–10:00 PM
Symposia Spotlight 1: Emerging Technologies in the Study of Neurodevelopmental Disorders
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Genes to Molecular Phenotypes
5:00–7:00 PM
Yukiko Gotoh, University of Tokyo
Genetic and Epigenetic Mechanisms of Cortical Development
Willow Coyote-Maestas, University of California, San Francisco
Deep Mutational Scanning Approaches to Correlate Structure and Function of Proteins
Sila Ultanir, Francis Crick Institute
Kinase Signaling in Neurodevelopmental Disorders
Short Talk(s) Chosen from Abstracts
Social Hour with Dinner
7:00–8:00 PM
Posters
7:30–10:00 PM
Thursday, January 21, 2027
Breakfast
7:00–8:00 AM
Circuits to Phenotypes
8:00–11:00 AM
Gabrielle Pouchelon, Cold Spring Harbor Laboratory
Transient Connectivity and Circuit Reprogramming in Cortical Development
Guillermina López Bendito, Instituto de Neurociencias
Spontaneous Activity–Gene Program Interplay in Circuits Development: Implications for Neurodevelopmental Disorders
Botond Roska †, Institute of Molecular and Clinical Ophthalmology (IOB) Basel
Asynchrony of Functional Connectivity in Developing Brain of ASD Models
Speaker to be Announced
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
Panel Discussion 1: What to Translate? When to Translate? How to Translate?
11:00–12:00 PM
Poster Setup
12:00–1:00 PM
On Own for Lunch
12:00–5:00 PM
Poster Viewing
1:00–10:00 PM
Career Roundtable
3:00–4:30 PM
Coffee Available
4:30–5:00 PM
Human and Non-Human Models
5:00–7:00 PM
Tomasz Nowakowski, University of California, San Francisco
Establishing Tools for Human Neuroscience
Pierre Vanderhaeghen, KU Leuven
Interrogating Human Specific and Neurodevelopmental Risk Genes using Chimeric Models
Paola Arlotta, Harvard University
Brain Organoids to Study Neurodevelopmental Disorders
Short Talk(s) Chosen from Abstracts
Social Hour with Dinner
7:00–8:00 PM
Posters
7:30–10:00 PM
Friday, January 22, 2027
Breakfast
7:00–8:00 AM
Environment and Experience
8:00–11:00 AM
Zhaolan (Joe) Zhou, University of Pennsylvania
Epigenetic Dissection of Mechanisms underlying Neurodevelopmental Disorders
Kristen J. Brennand, Yale School of Medicine
Insights into Gene-Environment Interactions in Neurodevelopmental Disorders
Gloria Choi, Massachusetts Institute of Technology
Cytokine Regulation of Brain and Behavior
Anca M. Pasca, Stanford University
Neonatal Hypoxia and Pediatric Risk Factors
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
Panel Discussion 2: Grand Challenges in NDDs
11:00–12:00 PM
On Own for Lunch
11:00–5:00 PM
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Neurmodulation, Biomarkers, and Therapies
5:00–7:00 PM
Stephan Sanders, University of Oxford
Gene Targeting Strategies for Autism and Neurodevelopmental Disorders
Allyson Berent,  Foundation for Angelman Syndrome Therapeutics/AS2Bio
The Parents’ Journey through Drug Development: Making the IMPOSSIBLE POSSIBLE-The Angelman Syndrome Story
Cassiano Carromeu †, Recursion
Using Human Pluripotent Stem Cell-Derived Neural Cultures to Assess Safety of New Drugs and Chemicals
Short Talk(s) Chosen from Abstracts
Meeting Wrap-Up: Outcomes and Future Directions
6:45–7:00 PM
Social Hour with Dinner
7:00–8:00 PM
Entertainment
8:00–11:00 PM
Cash Bar
8:00–11:00 PM
Saturday, January 23, 2027
Departure
12:00–11:59 PM

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