HIV and (Re)Emerging Viruses: Aligning Lessons Across Pandemics

Apr 08–11, 2024 | Herrenhausen Palace, Hannover, Germany
Scientific Organizers: Melanie M. Ott, Priti Kumar, Olivier Schwartz, and Alex Sigal

  In Person
  On Demand
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Apr 08–11, 2024 | Herrenhausen Palace, Hannover, Germany

Scientific Organizers: Melanie M. Ott, Priti Kumar, Olivier Schwartz, and Alex Sigal

Supported by the  Directors' Fund

***Meeting program subject to change.

Available Formats:   = In Person     = On Demand
Monday, April 8, 2024
Registration  
4:00–8:00 PM
 Grand Mussmann Hotel, Tivoli Room
Welcome Mixer  
6:00–8:00 PM
 Central-Hotel Kaiserhof
Tuesday, April 9, 2024
Breakfast  
8:00–9:00 AM
 Individual Hotel
Poster Setup  
8:30–9:00 AM
 Foyer
Welcome and Keynote Address  
9:00–10:00 AM
 Auditorium
Sarah Catherine Gilbert, University of Oxford
Preparing to Vaccinate Against the Next Pandemic
Poster Viewing  
9:00–7:00 PM
 Foyer
Pathogenesis I- Viral Emergence  
10:00–12:15 PM
 Auditorium
Stefan Pöhlmann, Deutsches Primatenzentrum GmbH
Principles of Coronaviral Infections
Geoffrey L. Smith, University of Oxford
Host-Virus Interactions with Monkeypox Virus
Jérémy Dufloo, Universitat de València
Short Talk: Short Talk: Viral Entry is a Weak Barrier to Zoonosis
Paige Fletcher, NIAID, NIH
Short Talk: Short Talk: Taï Forest Virus: The Virus Sequence Determines the Pathogenic Potential
Max Josef J Kellner, IMBA
Short Talk: Short Talk: Bat Organoids: Understanding Emerging Virus Infections through the Lens of Reservoir Species
Coffee Break  
10:30–10:50 AM
 Foyer
Lunch  
12:15–1:15 PM
 Ballroom
Poster Session 1  
1:00–3:00 PM
 Foyer
Career Roundtable  
3:30–4:30 PM
 Auditorium
Penny L. Moore, University of the Witwatersrand and National Institute for Communicable Diseases
Research Chair & Professor
Joel N. Blankson, Johns Hopkins School of Medicine
Professor of Medicine
Irini Sereti, NIAID, National Institutes of Health
Senior Investigator
Valentin Le Douce, BioNTech SE
Associate Director - Infectious Disease Vaccines
Coffee Available  
4:30–5:00 PM
 Foyer
Pathogenesis II- Molecular Mechanisms  
5:00–7:00 PM
 Auditorium
Melanie M. Ott, Gladstone Institute of Virology
How Viral Proteins Shape HIV and SARS-CoV-2 Pathogenesis
Wendy Barclay, Imperial College London
Lessons Learned from Flu and SARS-CoV-2
Kei Sato, The University of Tokyo
Pathogenicity of Omicron Subvariants
Sharon R. Lewin, University of Melbourne
mRNA Therapeutics for SARS-CoV2 and HIV latency
Lisa Lasswitz, University of Veterinary Medicine Hannover
Short Talk: Short Talk: CD81 is a Host Factor for Chikungunya Virus Replication
Social Hour with Lite Bites  
7:00–8:00 PM
 Ballroom
Wednesday, April 10, 2024
Breakfast  
8:00–9:00 AM
 Individual Hotel
Poster Setup  
8:30–9:00 AM
 Foyer
Common Lessons in Prevention  
9:00–12:00 PM
 Auditorium
Penny L. Moore, University of the Witwatersrand and National Institute for Communicable Diseases
Antibody Responses in People Living with HIV
Olivier Schwartz, Institut Pasteur
Entry and Replication of Human Seasonal Coronaviruses and Recent SARS-CoV-2 Variants
Joel N. Blankson, Johns Hopkins School of Medicine
Natural Immunity to HIV
Daniel Lingwood, Harvard Medical School
Short Talk: Short Talk: Eliciting a Single Amino Acid Change by Vaccination Enables Cross-Group Protective Influenza Antibodies
Matthew Sutton, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health
Short Talk: Short Talk: Evaluating Mechanisms of Protection by Broadly Reactive Anti-Alphavirus Antibodies
Poster Viewing  
9:00–7:00 PM
 Foyer
Coffee Break  
10:00–10:20 AM
 Foyer
Lunch  
12:00–1:00 PM
 Ballroom
Poster Session 2  
12:30–2:30 PM
 Foyer
Workshop 1  
2:30–4:30 PM
 Auditorium
Ulrike Lange, Heinrich Pette Institute
Transcriptional Activity of Proviral Sequences as Driver for Clonal Expansion in Chronic HIV Infection
Dania Figueroa Acosta, Icahn School of Medicine at Mount Sinai
Endocytic Recycling-Dependent Env Antigenic States Affect Neutralization of Cell-Free and Cell-Cell Infection by Broadly Neutralizing Antibodies
Uwem Etop George, African Centre of Excellence for Genomics of Infectious Diseases
Whole Genome Sequencing Reveals Cryptic Circulation of Dengue Virus in the Rainforest Region of Nigeria, West Africa
Shlomi Ilan, Ragon Institute of MGH, MIT and Harvard
Functional Antibody Signatures Following Combined Active and Passive Therapeutic Immunization of SHIV-infected Rhesus Macaques
Nell Saunders, Institut Pasteur
TMPRSS2 is a Functional Receptor for Human Coronavirus HKU1
Taha Y. Taha, Gladstone Institutes/UCSF
Spike-Independent Evolution of Recent SARS-CoV-2 Omicron Subvariants Enhances Viral RNA Replication via NSP6 Mutations
Florian Kabinger, Max Planck Institute for Multidisciplinary Sciences
Uncovering the Mechanism of Small Molecule Inhibitors Against the RNA Polymerase of SARS-CoV-2
Coffee Available  
4:30–5:00 PM
 Foyer
Drivers of Viral Evolution  
5:00–7:00 PM
 Auditorium
Alex Sigal, Africa Health Research Institute
SARS-CoV-2 Evolution and Pathogenesis in PLWH
Ravindra K. Gupta, University of Cambridge
SARS-CoV-2 Spike Evolution – Balancing Infectivity with Immune Evasion
Emma Hodcroft, University of Basel
Evolution of HIV and Other Viruses
Ann-Kathrin Reuschl, University College London
Short Talk: Short Talk: SARS-CoV-2 Evolution of Innate Immune Antagonism
Social Hour with Lite Bites  
7:00–8:00 PM
 Ballroom
Thursday, April 11, 2024
Breakfast  
8:00–9:00 AM
 Individual Hotel
Pushing the Boundaries on Viral Therapeutics  
9:00–12:00 PM
 Auditorium
Priti Kumar, Yale School of Medicine
HIV Gene Therapy: A Time to Prevent, a Time to Control, and Now, the Time to Cure
Galit Alter, Moderna, Inc.
Antibodies Therapeutics in HIV, SARS, Flu, and RSV
Michael Z. Lin, Stanford University School of Medicine
Short Talk: Short Talk: Design of Oral Antiviral Drugs for Broad-Spectrum Activity Against Coronaviruses
Vijayakumar Velu, Emory University
Short Talk: Short Talk: IL-15/IL-15Ra Cytokine Therapy Leads to Control of Viral Rebound in SIV Infected Macaques
Tomas Raul Wiche Salinas, Emory University
Short Talk: Short Talk: Persistent Reduction of SIV Reservoir Through Short-Term BCL-2 Inhibition at ART Initiation in Rhesus Macaques
Coffee Break  
10:00–10:20 AM
 Foyer
Lunch  
12:00–1:00 PM
 Ballroom
Hands-On Computer Workshop on Los Alamos HIV Sequence and Immunology Databases and Tools (HIV.lanl.gov)  
1:00–2:30 PM
 Auditorium
Brian T. Foley, Los Alamos National Lab
Los Alamos National Lab
Jennifer Mamrosh, Los Alamos National Laboratory
Los Alamos National Lab
Workshop 2  
2:30–4:30 PM
 Auditorium
Maria C Hesselman, University of Zurich
Distinct V2 Apex Broadly Neutralizing Antibody Modalities in Subtype B HIV-1 Infection
Doan C. Nguyen, Emory University
The Majority of SARS-CoV-2 Plasma Cells are Excluded from the Bone Marrow Long-Lived Compartment 33 Months after mRNA Vaccination
Sharidan Brown, Scripps Research
Anti-Immune Complex Antibodies are Elicited During Repeated Immunization with HIV Env Immunogens
Enrico Bravo, King's College London
IFNα2 Autoantibodies Post SARS-CoV-2 Wave 1 in India Are Associated with Lower Omicron Symptomology
Julia Hitschfel, Ragon Institute of MGH, MIT and Harvard
Transcriptional Profiling of HIV-Specific CD8 T Cell Responses From Lymph Nodes and Blood of Natural Controllers
Nicholas Provine, University of Oxford
Immune Signatures Associated with Failure to Seroconvert in Individuals Immunized with MVA-BN as a Vaccine Against MPOX
Wilfredo Garcia-Beltran, Ragon Institute of Mass General, MIT and Harvard
Evasion of NKG2D-Mediated Cytotoxic Immunity by Sarbecoviruses
Adam Zuiani, BioNTech US
A Multivalent mRNA Monkeypox Virus Vaccine (BNT166) Protects Mice and Macaques From Orthopoxvirus Disease
Coffee Available  
4:30–5:00 PM
 Foyer
Plenary PM  
5:00–6:45 PM
 Auditorium
Post-Acute Sequelae of Viral Infections  
6:45–7:00 PM
 Auditorium
Nadia R. Roan, University of California, San Francisco
Post-Acute Sequelae of COVID-19
Gabriella Worwa, NIH/NIAID/IRF-Frederick
Modeling Post-Acute Sequelae of Ebola Virus Disease
Irini Sereti, NIAID, National Institutes of Health
HIV and Chronic Immune Activation: The Impact of Low Nadir CD4 Counts
Till Omansen, Bernhard-Nocht-Institut für Tropenmedizin
Short Talk: Short Talk: Lassa Fever is Hallmarked by Inflammation and Kidney Injury or Neurological Disease: Results from the Lassa Fever PATHOGENESIS Study
Social Hour with Lite Bites  
7:00–8:00 PM
 Ballroom
Friday, April 12, 2024
Departure  
12:00–11:59 PM

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