***Meeting program subject to change.
Available Formats: = In Person
= On Demand
4:00–8:00 PM
Riverview Lounge
6:00–8:00 PM
Riverview Lounge
7:00–8:00 AM
Alberta/New Brunswick
Welcome and Keynote Address
8:00–9:00 AM
Cascade Ballroom
Elaine Hurt, AstraZeneca
Lessons Learned from 30 Years of ADC Development
Computational Technologies for Antibody Design and Optimization
9:00–11:15 AM
Cascade Ballroom
Charlotte Deane, University of Oxford
How Far are we from Designing an Antibody Therapeutic on a Computer
Peter S. Kim, Stanford University
Unsupervised Evolution of Protein and Antibody Complexes with a Structure-Informed Language Model
Peyton Greenside, BigHat Biosciences
Combining Active Learning with a Rapid Synthetic Biology Platform to Design Therapeutic Antibodies
Short Talk(s) Chosen from Abstracts
9:30–9:50 AM
Riverview Lounge
11:15–1:00 PM
Alberta/New Brunswick
1:00–10:00 PM
Alberta/New Brunswick
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Cascade Ballroom
Short Talks Chosen from Abstracts
4:30–5:00 PM
Riverview Lounge
Antibody Activity on Demand - Engineering Strategies to Emerging Clinical Outcomes
5:00–7:00 PM
Cascade Ballroom
Naoka Hironiwa, Chugai Pharmabody Research
Antibody Activation using Ca2+ or ATP-Switches
Carl U Bialucha, Xilio Therapeutics
Talk Title to be Announced
Dikran Aivazian, Adaxion Therapeutics
Engineering of Hypoimmunogenic Biotherapeutics through a Novel bioconjugate Platform
Short Talk(s) Chosen from Abstracts
7:00–8:00 PM
Alberta/New Brunswick
7:30–10:00 PM
Alberta/New Brunswick
7:00–8:00 AM
Alberta/New Brunswick
Emerging Antibody-based Modalities and Engineering Strategies
8:00–11:00 AM
Cascade Ballroom
Jo L. Viney, Seismic Therapeutic
AI/ML for Biologics Drug Discovery for Immunology
James A Wells, University of California, San Francisco
Degraders to Attack the Cancer Surfaceomewell
Paul Carter, Genentech, Inc.
Engineering Antibodies to Improve High Concentration Properties for Subcutaneous Delivery
E. Sally Ward, University of Southampton
Targeting Subcellular Trafficking for the Generation of Therapeutics
Short Talk(s) Chosen from Abstracts
9:00–9:20 AM
Riverview Lounge
11:00–1:00 PM
Alberta/New Brunswick
1:00–10:00 PM
Alberta/New Brunswick
Career Roundtable (Joint)
1:45–2:45 PM
Alhambra
4:30–5:00 PM
Riverview Lounge
5:00–5:45 PM
Cascade Ballroom
David Baker, University of Washington
Computational Design of Proteins for Therapeutic Applications
5:45–7:00 PM
Cascade Ballroom
Greg Thurber, University of Michigan
Optimizing ADC Delivery by Avidity/Affinity Tuning
William M Flanagan, Avidity Biosciences, Inc.
Antibody-Oligonucleotide Conjugates
Short Talk(s) Chosen from Abstracts
7:00–8:00 PM
Alberta/New Brunswick
7:30–10:00 PM
Alberta/New Brunswick
7:00–8:00 AM
Alberta/New Brunswick
Harnessing the Immune System with Antibodies
8:00–11:00 AM
Cascade Ballroom
Eric Smith, Regeneron Pharmaceuticals, Inc.
CD28 Bispecifics for Costimulation of T Cells
Pamela M. Holland, InduPro
Proximity Labeling to Identify Target Pairs for ADCs and T Cell Engagers
John R. Desjarlais, Xencor, Inc.
T Cell Engagers
Rony Dahan, Weizmann Institute of Science
Recruitment of Dendritic Cells with Bispecifics / Fc Glycoengineering
Short Talk(s) Chosen from Abstracts
9:00–9:20 AM
Riverview Lounge
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Cascade Ballroom
Short Talks Chosen from Abstracts
4:30–5:00 PM
Riverview Lounge
Experience with Antibodies Beyond Oncology
5:00–6:15 PM
Cascade Ballroom
Karen Silence, arGEN-X BVBA
Agonist MuSK Antibodies for the Treatment of Myasthenia Gravis
James E Crowe, Jr., Vanderbilt University Medical Center
Human Monoclonal Antibodies for Emerging Infections
Short Talk(s) Chosen from Abstracts
6:15–7:00 PM
Cascade Ballroom
Erica O Saphire, La Jolla Institute for Immunology
New Antibodies Against an Old Virus
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
7:00–7:15 PM
Cascade Ballroom
7:15–8:15 PM
Alberta/New Brunswick
