Feb 23–26, 2026 | Keystone Resort, Keystone, CO, United States
Scientific Organizers:
Vijay G. Sankaran, Anna E. Beaudin, and Esther Obeng
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Scientific Organizers: Vijay G. Sankaran, Anna E. Beaudin, and Esther Obeng
Vijay G. Sankaran
Boston Children’s Hospital
Anna E. Beaudin, PhD
University of Utah School of Medicine
Esther Obeng
St. Jude Children's Research Hospital
***Meeting program subject to change.
Available Formats: = In Person = On DemandMonday, February 23, 2026
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Tuesday, February 24, 2026
Mosaicism in Hematopoiesis
Human Developmental Hematopoiesis
Zebrafish Developmental Hematopoiesis
Developmental Hematopoiesis
Short Talk: Spatiotemporal and Molecular Regulation of Embryonic Lymphoid Progenitor Production
Unfolded Protein Response Signaling Promotes Myeloid Cell Production and Cooperates with Oncogenic Mutation
CD90 – More Than just a Stem Cell Marker: Implication for Blood Development, Cancer Immunotherapy, and Gene Therapy
Clonal Hematopoiesis
Single Cell Biology of Hematologic Malignancies
An Unusual Friendship: How Gut Microbiota and Endogenous Retroviruses (ERVs) Interact to Support Hematopoiesis?
MYC as a Central Rheostat in Fanconi Anemia Associated Hematopoiesis Failure
Megakaryocyte p53 activation in ANKRD26-Related Thrombocytopenia and Leukemia Predisposition
Enhancing Translation Fidelity Confers Hematopoietic Stem Cells with Increased Resistance to Stress and Suppresses Cancer Initiation
Stress-responsive Embryonic HSC Fate is Balanced via the AHR-NLRP3 Inflammasome Axis
PITPβ is Required for Malignant pAKT Activation and the Development of Jak2 V617F-Induced Myeloproliferative Neoplasms (MPN) in Mice
Clonal Dynamics of HSC Contributions to Hematopoiesis
Stress Responses in HSCs
Metabolic Regulation of HSCs
Short Talk: An IFN-gamma-Mediated Adaptive Immune Signaling Axis in Bone Marrow Reprograms Hematopoietic Stem Cells to Improve Myeloid Function
Short Talk: MECOM Expression Tracks Haematopoietic Development from Artery to Engraftable iHSCs
Wednesday, February 25, 2026
Imaging of the Bone Marrow Spatial Architecture
Regulation of Hematopoiesis and Bone Marrow Failure Syndromes by Dysregulated Endothelial Cells
MPN Microenvironment
Niche Regulation of HSCs
Short Talk: Depletion of Microenvironmental Syndecan-2 Impairs Hematopoietic Stem Cell Self-Renewal and Cytokine Responses
Short Talk: Mammalian Bone Marrow Adipocytes Fuel Hematopoietic Maintenance and Regeneration
Inflammatory Cytokines in Clonal Hematopoiesis
Telomere Disorders and Hematopoiesis
Insights from Blood Disorders Enable New Therapies
Short Talk: Clonal Hematopoiesis and the Aging Brain
Short Talk: Impaired Polyamine Metabolism Drives Hematopoietic Aging
Thursday, February 26, 2026
Lineage Tracing of Native Hematopoiesis
Extrinsic Regulators of Hematopoietic Progenitor Commitment
HSC Regulation by the Proteostasis Network
In Vivo Genome Engineering of HSCs in Sickle Cell Disease
Short Talk: Clonal Multi-omics Uncovers CD200 as a Marker for Bona Fide HSCs
Short Talk: Stalled B Cell Development as a Convergent Mechanism for Germline Predisposition to Childhood Leukemia
Netrin-1 Regulates Hematopoietic Stem Cell Function via UNC5A
Stem Cell Function and Hematopoiesis in the Absence of Carbohydrate Oxidation and Fermentation
Piezo1 Mechanosensing as a Druggable Target to Enhance Hematopoietic Stem Cell Homing to Bone Marrow
Asynchronous Acquisition of Hematopoietic Stem Cell Functional Maturity During Postnatal Development
YY1 Depletion Reprograms Committed Murine Pro-B Cells to Acquire Hematopoietic Stem Cell Properties
PRC2 Times Sequential Metabolic–Autophagy Transitions to Coordinate Terminal Erythropoiesis
Regulation of Ribosomal RNA Transcription by MYC in Hematopoiesis
Molecular Cartography of Emergency Myelopoiesis Reveals Conserved Modules of Hematopoietic Activation in Inflammation and Leukemia
Myeloid Malignancies
Pathogenesis of MDS
What Makes a Stem Cell a Stem Cell and How Does It Go Bad
Short Talk: Unraveling Stemness Mechanisms in MECOM Rearranged Acute Myeloid Leukemias
Friday, February 27, 2026
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