Antibodies as Drugs: Evolving Designs, Formats and Approaches

Feb 22–25, 2027 | Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers: James E Crowe, Jr., Lisa Purcell, and Jonah Rainey

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Feb 22–25, 2027 | Fairmont Banff Springs, Banff, AB, Canada

Scientific Organizers: James E Crowe, Jr., Lisa Purcell, and Jonah Rainey

Supported by the  Directors' Fund

***Meeting program subject to change.

Available Formats:     = Livestream   = In Person     = On Demand
Monday, February 22, 2027
Registration
4:00–8:00 PM
Welcome Mixer
6:00–8:00 PM
Tuesday, February 23, 2027
Breakfast
7:00–8:00 AM
Welcome Remarks (Joint)
8:00–8:10 AM
Keynote Address (Joint)
8:10–9:00 AM
James Zou, Stanford University
The Virtual Lab
Drug Design and Preclinical Development: Stimulating Therapeutics and Translation (Joint)
9:00–11:15 AM
Dean Ho, National University of Singapore
Prospectively Adjusting Human Drug Dosing - Dynamically - for Oncology
Karen Akinsanya †, Schrödinger
Talk Title to be Announced
Philip Kim, University of Toronto
Computation and Artificial Intelligence-Based Methods for Better Antibody Development
Pahini Pandya, Panakeia Technologies
Talk Title to be Announced
Short Talk(s) Chosen from Abstracts
Coffee Break
9:30–9:50 AM
Poster Setup
11:15–1:00 PM
On Own for Lunch
11:15–5:00 PM
Poster Viewing
1:00–10:00 PM
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Bispecific Antibodies for Co-Engagement and Co-Stimulation
5:00–7:00 PM
Shelley Force Aldred, Rondo Therapeutics
T-Cell Co-Stimulatory Bispecific Antibodies for Treating Solid Tumors
Ulrike Philippar †, Janssen Research & Development
Talk Title to be Announced
Brenda O'Connell †, Bicara Therapeutics
EGFR-TGFb Bifunctional Antibody
Short Talk(s) Chosen from Abstracts
Social Hour with Dinner
7:00–8:00 PM
Posters
7:30–10:00 PM
Wednesday, February 24, 2027
Breakfast
7:00–8:00 AM
New Dosing and Use Paradigms for Multispecific Antibodies
8:00–11:00 AM
Paul W. H. I. Parren, Leiden University Medical Center
Deep-Depletion of Tissue-Resident Pathogenic Immune Cells
Yvonne Y. Chen †, University of California, Los Angeles
Bispecific Logic-Gated CAR-T Cells
Nina Weisser, Zymeworks BC Inc.
TriTCE Co-stim: A Differentiated T Cell Engager Platform with Conditional cis CD28 Co-Stimulation and Transferability to Diverse Targeting Strategies
Jeanette H.W. Leusen, University Medical Center Utrecht
Targeting FcgRI for Auto-Immune Disease
Jonah Rainey, Lilly
Talk Title to be Announced
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
Panel Discussion 1: What VCs and Private Investors Really Want: The Difference between Exciting Data and a Value Inflection Point
11:00–12:00 PM
Poster Setup
11:00–1:00 PM
On Own for Lunch
11:00–5:00 PM
Poster Viewing
1:00–10:00 PM
Career Roundtable
3:00–4:30 PM
Coffee Available
4:30–5:00 PM
Conditionally and Selectively Active Antibodies
5:00–6:30 PM
Meike Logtenberg, Merida Biosciences
Selective Binding and Clearance of Pathogenic Antibodies
Sophia Hober, KTH Royal Institute of Technology
Ca Regulated Molecular Switch
Short Talk(s) Chosen from Abstracts
Panel Discussion 1: The Cutting-Edge of Antibody Engagement
6:30–7:00 PM
Social Hour with Dinner
7:00–8:00 PM
Posters
7:30–10:00 PM
Thursday, February 25, 2027
Breakfast
7:00–8:00 AM
Application of Innovations to Exogenous Antibody Targets to Expand Breadth and Efficacy
8:00–11:00 AM
David Veesler, University of Washington
Antibody Inhibition of Activation Mechanisms of Coronavirus Spike
Laura M Walker, Moderna
Alternative Expression of Antibodies
James E Crowe, Jr., Vanderbilt University Medical Center
Human Monoclonal Antibodies for Emerging Infectious Diseases
Lisa Purcell, Third Rock Ventures
Novel Structure-Guided Functional Improvement of Antibody Breadth and Potency
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
Panel Discussion 2: Navigating the Regulatory Landscape: How Companies are Thinking about US Uncertainty and Leveraging Global Regulatory Authorities
11:00–12:00 PM
On Own for Lunch
11:00–5:00 PM
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Novel Scaffolds and Immunoconjugates
5:00–6:30 PM
Max Houry †, atbtherapeutics
Peptide Payload ATBody
Jason Laliberte, AstraZeneca
VHH-Based Antibodies for Broad Influenza Targeting
Anette Sommer, Synaffix B.V. - Lonza ADS
GlycoConnect® Technology for Best-in-Class ADCs – Emerging Clinical Insights
Short Talk(s) Chosen from Abstracts
Panel Discussion 3: How Far Is Too Far: Target Engagement, Computational Design and New Scaffolds
6:30–7:00 PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Social Hour with Dinner
7:00–8:00 PM
Entertainment
8:00–11:00 PM
Cash Bar
8:00–11:00 PM
Friday, February 26, 2027
Departure
12:00–11:59 PM

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