Joint with: Hematopoiesis
Myeloid Cells: Functional Heterogeneity with Therapeutic Promise
Feb 23–26, 2026 | Keystone Resort, Keystone, CO, United States
Scientific Organizers:
Charlotte L. Scott, Shalin H. Naik, and Thomas Fabre
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Feb 23–26, 2026 | Keystone Resort, Keystone, CO, United States
Scientific Organizers: Charlotte L. Scott, Shalin H. Naik, and Thomas Fabre
Charlotte L. Scott, PhD
University of Ghent & VIB
Charlotte L. Scott, Ph.D., is an Associate Professor at Ghent University and a Principal Investigator at the Flemish Institute for Biotechnology (VIB), Belgium. Her lab is focused on identifying distinct subsets of hepatic myeloid cells across species, assessing the factors driving the identity of the different populations and examining their specific functions in the context of tissue injury and repair. Dr. Scott's contributions have significantly advanced our understanding of myeloid cell biology, with potential implications for developing new treatments for cancer, liver disease, and other inflammatory conditions. She was recently awarded the Ita Askonas prize for outstanding female immunologists. In 2023 she co-organized the annual meeting of the European Macrophage and Dendritic cell society (EMDS@VIB) which was a resounding success with more than 600 participants from across the globe.
Shalin H. Naik, PhD
Walter & Eliza Hall Institute
Shalin H. Naik, Ph.D., is a Professor in the Immunology Division at the Walter & Eliza Hall Institute of Medical Research in Australia. His lab studies several processes including hematopoiesis, immunology, development and cancer through the lens of clones utilizing novel technologies. His focus on hematopoiesis has led to discoveries in the pathways of dendritic cell and myeloid cell development, including the translation of protocols for cell therapies. Dr. Naik's contributions have been instrumental in advancing immunology and hematology, with potential applications in improving disease detection, treatment, and overall health outcomes. He has been awarded numerous prizes including the Burnet Prize, is well published and has hosted several conferences including Oz Single Cell, which is now in its eighth year.
Thomas Fabre
Pfizer
Thomas Fabre, Ph.D., is a Senior Principal Scientist (Associate Director) in the discovery myeloid and tissue remodeling group in the Inflammation and Immunology research unit at Pfizer Inc. His research focuses on understanding myeloid cell heterogeneity and function in inflammatory and fibrotic diseases to identify and target “core” pathogenic subsets. He is currently leading two academic–industry collaborations focused on unravelling myeloid cell functional heterogeneity using single-cell spatial proteomics and in vivo Perturb-seq. Dr. Fabre's contributions have significantly advanced our understanding of macrophage biology and its implications for liver and lung diseases. Dr. Fabre recently received an innovation and breakthrough award for his work on scar-associated macrophages in fibrosis.
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In Person
On Demand
***Meeting program subject to change.
Available Formats: = In Person = On DemandMonday, February 23, 2026
Fundraising
Booking Function
Merchandise Options
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Registration
4:00–8:00 PM
Welcome Mixer
6:00–8:00 PM
Tuesday, February 24, 2026
Breakfast
7:00–8:00 AM
Welcome Remarks (Joint)
8:00–8:10 AM
Keynote Address (Joint)
8:10–9:00 AM
Shannon J Turley, Amgen Inc.
Manipulating Stromal-Myeloid Cell Crosstalk for Therapeutic Purposes
Manipulating Stromal-Myeloid Cell Crosstalk for Therapeutic Purposes
Myeloid Cell Development, Recruitment and Fate
9:00–11:30 AM
Shalin H. Naik, Walter & Eliza Hall Institute
Next-generation CAR-DC1 Immunotherapy
Next-generation CAR-DC1 Immunotherapy
Florent Ginhoux, Gustave Roussy
DC Heterogeneity in Disease
DC Heterogeneity in Disease
Heping Xu, Westlake University
Airway Neutrophil Recruitment by Alarmin-Loaded Extracellular Lipid Droplets
Airway Neutrophil Recruitment by Alarmin-Loaded Extracellular Lipid Droplets
Cindy Audiger †, Walter and Eliza Hall Institute of Medical Research
Short Talk: Emergency Type 1 Conventional Dendritic Cells - eDC1s - A Novel Hybrid Cell State with Progenitor-like and DC1-like Features
Short Talk: Emergency Type 1 Conventional Dendritic Cells - eDC1s - A Novel Hybrid Cell State with Progenitor-like and DC1-like Features
Shiba Prasad Dash †, Indian Institute of Technology Roorkee, Roorkee, India
Short Talk: The CEBPD Transcription Factor Regulates Granulocyte Lineage Commitment and Mature Neutrophil Functions
Short Talk: The CEBPD Transcription Factor Regulates Granulocyte Lineage Commitment and Mature Neutrophil Functions
Jichang Han, Washington University in St Louis
Short Talk: Inter-Relationship of Peritoneal Fluid and Mesothelial Border Macrophages and Two Different Pathways Exist in Their Maintenance and Repopulation
Short Talk: Inter-Relationship of Peritoneal Fluid and Mesothelial Border Macrophages and Two Different Pathways Exist in Their Maintenance and Repopulation
Coffee Break
9:30–9:50 AM
Poster Setup
11:30–1:00 PM
On Own for Lunch
11:30–2:30 PM
Poster Viewing
1:00–10:00 PM
Symposia Spotlight 1: Novel Insights into Myeloid Cell Functional Heterogneity
2:30–4:30 PM
Noelia Alonso Gonzalez †, University of Muenster
Organ-specific Efferocytosis is Temporally Regulated through the Cooperation of MARCO and TIM4
Organ-specific Efferocytosis is Temporally Regulated through the Cooperation of MARCO and TIM4
Megan M Hanlon †, BWH, Harvard Medical School
Pathogenic Role of SPP1+ Macrophages in Rheumatoid Arthritis
Pathogenic Role of SPP1+ Macrophages in Rheumatoid Arthritis
Bram Verstappe †, IRC/VIB/UGent
Zeb1 Expression by cDC1s Is Crucial for Maintenance of Splenic cDC1s and Macrophages
Zeb1 Expression by cDC1s Is Crucial for Maintenance of Splenic cDC1s and Macrophages
Silvia Pires †, Weill cornell medicine
Innate lymphoid Cells Activated by TL1A Link Colitis with Emergency Granulopoiesis and Drive Tumor Promoting Colonic Neutrophils
Innate lymphoid Cells Activated by TL1A Link Colitis with Emergency Granulopoiesis and Drive Tumor Promoting Colonic Neutrophils
Wyatt Schug †, University of Virginia
Expansion of Basophil Heterogeneity in Cardiometabolic Disease Depends on Hematopoietic Organ of Origin
Expansion of Basophil Heterogeneity in Cardiometabolic Disease Depends on Hematopoietic Organ of Origin
Pieter Adriaan Louwe †, VIB Center for Inflammation Research
MASLD-induced Ceroid-laden Macrophage Aggregates Persist following Recovery and Underpin a Prolonged State of Heightened Hepatic Sensitivity
MASLD-induced Ceroid-laden Macrophage Aggregates Persist following Recovery and Underpin a Prolonged State of Heightened Hepatic Sensitivity
Nidhi Jalan-Sakrikar †, Mayo Clinic
Neutrophil Heterogeneity in Cholestatic Liver Disease
Neutrophil Heterogeneity in Cholestatic Liver Disease
Joanna M Bandola-Simon †, National Cancer Institute
Defective MHC-II Peptide Editing in Dendritic Cells Impairs CD4⁺ T Cell Priming and Promotes Tumor Immune Evasion
Defective MHC-II Peptide Editing in Dendritic Cells Impairs CD4⁺ T Cell Priming and Promotes Tumor Immune Evasion
Coffee Available
4:30–5:00 PM
Myeloid Cells in Tumors
5:00–7:00 PM
Ariel Munitz, Tel Aviv University
Eosinophils in the Tumor Microenvironment
Eosinophils in the Tumor Microenvironment
Stefani Spranger, Massachusetts Institute of Technology
The Role of Dendritic Cells in Shaping Anti-Tumor Immunity
The Role of Dendritic Cells in Shaping Anti-Tumor Immunity
Jennifer Guerriero, Brigham and Women's Hospital
Myeloid Cells as Immunotherapy for Breast Cancer
Myeloid Cells as Immunotherapy for Breast Cancer
Samarth Hegde †, Icahn School of Medicine at Mount Sinai
Short Talk: Myeloid Progenitor Dysregulation Fuels Immunosuppressive Macrophages in Tumors
Short Talk: Myeloid Progenitor Dysregulation Fuels Immunosuppressive Macrophages in Tumors
Xiaolei Su, Yale School of Medicine
Short Talk: Engineering Mast Cells to Kill Solid Tumors
Short Talk: Engineering Mast Cells to Kill Solid Tumors
Social Hour with Dinner
7:00–8:00 PM
Poster Session 1
7:30–10:00 PM
Wednesday, February 25, 2026
Breakfast
7:00–8:00 AM
Myeloid Cell Functions in Disease Contexts
8:00–11:00 AM
Charlotte L. Scott, University of Ghent & VIB
Hepatic Macrophage Heterogeneity in MASLD and MASLD-associated HCC
Hepatic Macrophage Heterogeneity in MASLD and MASLD-associated HCC
Lai Guan Ng, Shanghai Immune Therapy Institute
Harnessing Neutrophil Heterogeneity for Biomarker Development and Targeted Treatment
Harnessing Neutrophil Heterogeneity for Biomarker Development and Targeted Treatment
Hawa Racine Thiam, Stanford University
Engineering NETosis in Disease
Engineering NETosis in Disease
Elizabeth Wayne, University of Washington
Engineering Monocyte Cell Fate in Disease
Engineering Monocyte Cell Fate in Disease
Thu (Autumn) Doan †, University of Colorado Anschutz
Short Talk: Islet Macrophages Modulate Antigen Presentation during Type 1 Diabetes
Short Talk: Islet Macrophages Modulate Antigen Presentation during Type 1 Diabetes
Daniel Puleston †, Icahn School of Medicine at Mount Sinai
Short Talk: Impaired Serine Metabolism Drives Age-Related Decline in Resident Tissue Macrophage Maintenance and Function
Short Talk: Impaired Serine Metabolism Drives Age-Related Decline in Resident Tissue Macrophage Maintenance and Function
Coffee Break
9:00–9:20 AM
Poster Setup
11:00–1:00 PM
On Own for Lunch
11:00–5:00 PM
Poster Viewing
1:00–10:00 PM
Career Roundtable (Joint)
1:45–2:45 PM
Panel Discussion: Making Sense of the Mess: How to Bring Together the Different Subsets Identified using scRNA-Seq in Different Studies
3:00–4:30 PM
Coffee Available
4:30–5:00 PM
Functional Heterogeneity of Myeloid Cells Across Tissues
5:00–7:00 PM
Kurt Zimmerman, University of Oklahoma Health Sciences Center
Functional Heterogeneity of Kidney Macrophages
Functional Heterogeneity of Kidney Macrophages
Isabelle C Arnold, University of Zurich
Eosinophils in the Gastrointestinal Tract
Eosinophils in the Gastrointestinal Tract
David Sancho, Centro Nacional de Investigaciones Cardiovasculares, CNIC
Metabolic Control of Myeloid Cell Function
Metabolic Control of Myeloid Cell Function
Andri Leo Lemarquis †, City of Hope (COH)
Short Talk: Apoptotic HSPA5 Engages Macrophage TLR4 to Scale T Cell Production
Short Talk: Apoptotic HSPA5 Engages Macrophage TLR4 to Scale T Cell Production
Xiangyue Zhang †, Stanford University
Short Talk: Erythropoietin Receptor on cDC1s Dictates Immune Tolerance
Short Talk: Erythropoietin Receptor on cDC1s Dictates Immune Tolerance
Social Hour with Dinner
7:00–8:00 PM
Poster Session 2
7:30–10:00 PM
Thursday, February 26, 2026
Breakfast
7:00–8:00 AM
Myeloid Cells in Infection
8:00–11:00 AM
Calum C. Bain, University of Edinburgh
Role of Macrophages in Pulmonary Infections
Role of Macrophages in Pulmonary Infections
Lidia Bosurgi, University Medical Center Hamburg-Eppendorf
Harnessing Macrophage Efferocytosis to Promote Tissue Repair and Remodeling
Harnessing Macrophage Efferocytosis to Promote Tissue Repair and Remodeling
Bryan D. Bryson, Massachusetts Institute of Technology
Reprogramming Myeloid Cells to Improve Bacterial control
Reprogramming Myeloid Cells to Improve Bacterial control
Ruoqiong Cao †, Baylor College of Medicine
Short Talk: Infection Activated Hematopoietic Stem Cells (IA-HSCs) Mediate Central Trained Immunity
Short Talk: Infection Activated Hematopoietic Stem Cells (IA-HSCs) Mediate Central Trained Immunity
Mimi Kostska †, NYU Langone Health
Short Talk: Splenic Sentinels: Marginal Zone Macrophages Restrain Staphylococcus Aureus Virulence and Enable Effective Neutrophil Mediated Clearance
Short Talk: Splenic Sentinels: Marginal Zone Macrophages Restrain Staphylococcus Aureus Virulence and Enable Effective Neutrophil Mediated Clearance
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–2:30 PM
Symposia Spotlight 2: Going from scRNA-seq to Meaningful Biology
2:30–4:30 PM
Aimée Bugler-Lamb †, VIB
Combining In Vivo CRISPR Screens with Computational Modeling to Identify the Causal Circuits Driving KC Identity and Function.
Combining In Vivo CRISPR Screens with Computational Modeling to Identify the Causal Circuits Driving KC Identity and Function.
Glenn De Lange †, University of Zurich
Eosinophil Subset Dynamics and Transcriptional Signatures in Colorectal Cancer Progression
Eosinophil Subset Dynamics and Transcriptional Signatures in Colorectal Cancer Progression
Christopher J Molina †, University of California San Francisco
Macrophage Heterogeneity and TGF-β-Independent Fibroblast Crosstalk in Pulmonary Fibrosis
Macrophage Heterogeneity and TGF-β-Independent Fibroblast Crosstalk in Pulmonary Fibrosis
Chinyere Iweka †, Case Western Reserve University
NAD⁺ Decline Reprograms Monocyte Metabolism to Drive Age-Related Neuroinflammation after Stroke
NAD⁺ Decline Reprograms Monocyte Metabolism to Drive Age-Related Neuroinflammation after Stroke
Preethy Parthiban †, Stanford
Role of Neutrophil–Macrophage Crosstalk in Abnormal Saccular Stage Lung Development
Role of Neutrophil–Macrophage Crosstalk in Abnormal Saccular Stage Lung Development
Stijn Verwaerde †, Vlaams Instituut voor Biotechnologie, Ghent University
Innate Type-2 Lymphocytes Trigger an Inflammatory Switch in Alveolar Macrophages
Innate Type-2 Lymphocytes Trigger an Inflammatory Switch in Alveolar Macrophages
Alexander Moshensky †, University of California, Irvine
Trajectories and Kinetics of Tumor-associated Macrophage Plasticity in vivo
Trajectories and Kinetics of Tumor-associated Macrophage Plasticity in vivo
Marc Wadsworth †, Pfizer
Mapping the Myeloid Mosaic: Building a Multi-Organ Atlas to Decipher Macrophage Diversity in Fibrosis and Inflammation
Mapping the Myeloid Mosaic: Building a Multi-Organ Atlas to Decipher Macrophage Diversity in Fibrosis and Inflammation
Coffee Available
4:30–5:00 PM
Targeting Myeloid Cells in Disease
5:00–7:00 PM
Thomas Fabre, Pfizer
Utilizing Macrophages to Treat Fibrosis
Utilizing Macrophages to Treat Fibrosis
Filipe Pereira, Lund University and Asgard Therapeutics
Conversion of Cancer Cells into Dendritic Cells to Reinstate Cancer Immunity
Conversion of Cancer Cells into Dendritic Cells to Reinstate Cancer Immunity
Adam Freund, Arda Therapeutics
Evaluating the Consequences of Antibody-Drug Conjugate-Mediated Depletion of Myeloid Cells in Liver Fibrosis
Evaluating the Consequences of Antibody-Drug Conjugate-Mediated Depletion of Myeloid Cells in Liver Fibrosis
Kristen Radford, University of Queensland
Human DCs in Cancer Models
Human DCs in Cancer Models
Meeting Wrap-Up: Outcomes and Future Directions
7:00–7:15 PM
Social Hour with Dinner
7:15–8:15 PM
Entertainment
8:00–11:00 PM
Cash Bar
8:00–11:00 PM
Friday, February 27, 2026
Departure
12:00–11:59 PM
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