B and T Cell Collaboration in Lymphoid and Nonlymphoid Microenvironments
Mar 16–19, 2026 | Keystone Resort, Keystone, CO, United States
Scientific Organizers:
Stephanie C. Eisenbarth, Jason G Cyster, and Ziv Shulman
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Mar 16–19, 2026 | Keystone Resort, Keystone, CO, United States
Scientific Organizers: Stephanie C. Eisenbarth, Jason G Cyster, and Ziv Shulman
Stephanie C. Eisenbarth
Northwestern University Feinberg School of Medicine
Stephanie Eisenbarth, M.D., Ph.D. is Professor of Medicine and Pathology at Northwestern University Feinberg School of Medicine where she is Chief of Allergy and Immunology and the inaugural Director of the Center for Human Immunobiology. Dr. Eisenbarth’s research focuses on understanding how dendritic cells, T cells, and B cells interact to regulate immune responses. Her work spans both protective antibody responses, such as those generated by vaccines, and pathogenic antibody responses, such as those involved in allergies and alloimmunization. Dr. Eisenbarth has experience in organizing international meetings, including the recent 2024 Gordon Research Conference on Food Allergy.
Jason G Cyster, PhD
HHMI/University of California, San Francisco
Jason G. Cyster, Ph.D., is a Professor in the Department of Microbiology & Immunology at the University of California, San Francisco, and an Investigator of the Howard Hughes Medical Institute. He is widely regarded as a pioneer in defining the molecular cues organizing secondary lymphoid tissues and tertiary lymphoid structures that support B cell responses. He currently serves as the director of UCSF’s Immunology Training Program. Dr. Cyster is an elected member of the National Academy of Sciences and the American Academy of Arts and Sciences.
Ziv Shulman, PhD
Weizmann Institute
Ziv Shulman, Ph.D., is an associate professor of immunology at the Weizmann Institute of Science. His research aims to understand how antibodies evolve in response to vaccination, infection, and cancer, focusing on an antibody evolutionary process. Shulman’s work revealed molecular mechanisms that drive the increase in the affinity of antibodies in lymphoid organs using advanced imaging techniques. Furthermore, he examines the role of antibodies in more complex microenvironments such as mucosal tissues and human cancer. Dr. Shulman has successfully organized scientific meetings including EMBO’s 20th Germinal Center Conference 2022.
Available Formats:
Supported by the Directors' Fund
In Person
On Demand
***Meeting program subject to change.
Available Formats: = In Person = On DemandMonday, March 16, 2026
Fundraising
Booking Function
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CU Anschutz Pre-Conference Workshop: Networking & Communication Skills (separate registration required) Learn more at: https://keysym.us/CUAnschutz26
12:00–3:00 PM
Registration
4:00–8:00 PM
Welcome Mixer
6:00–8:00 PM
Tuesday, March 17, 2026
Breakfast
7:00–8:00 AM
Welcome Remarks (Joint)
8:00–8:10 AM
Keynote Address (Joint)
8:10–9:00 AM
Carola G. Vinuesa, Francis Crick Institute
Regulation of Humoral Immunity
Regulation of Humoral Immunity
Generation and Maintenance of Humoral Memory (Joint)
9:00–11:30 AM
Kim Good-Jacobson, Monash University
Memory B Cells and Plasma Cells in Acute and Chronic Viral Infections
Memory B Cells and Plasma Cells in Acute and Chronic Viral Infections
Taras Kreslavsky, Karolinska Institutet
The Multilayered Identity of B Cell Memory
The Multilayered Identity of B Cell Memory
Frances E. Lund, University of Alabama at Birmingham
Pathogen-Specific Memory B Cell Subsets and Antibody Production
Pathogen-Specific Memory B Cell Subsets and Antibody Production
Shane Crotty, La Jolla Institute for Immunology
Short Talk: Germline-Targeting Vaccine Elicits HIV Broadly Neutralizing Antibodies In Nonhuman Primates
Short Talk: Germline-Targeting Vaccine Elicits HIV Broadly Neutralizing Antibodies In Nonhuman Primates
Gowthaman Uthaman, University of Massachusetts Chan Medical School
Short Talk: Lymph Node ILC2s Drive Tfh13 Cell Differentiation and Anaphylactic IgE Responses
Short Talk: Lymph Node ILC2s Drive Tfh13 Cell Differentiation and Anaphylactic IgE Responses
Coffee Break
9:30–9:50 AM
Poster Setup
11:30–1:00 PM
On Own for Lunch
11:30–5:00 PM
Poster Viewing
1:00–10:00 PM
Meet the Editors (Joint)
1:15–2:15 PM
Symposia Spotlight 1
2:30–4:30 PM
Lauren A. Hesser, Eli Lilly & Company
Intestinal T-bet+ Plasmablasts Mediate Epithelial Barrier Dysfunction and Inflammatory Bowel Disease
Intestinal T-bet+ Plasmablasts Mediate Epithelial Barrier Dysfunction and Inflammatory Bowel Disease
Gabrielle R Berman, NYU Langone Health
Lymphatic Control of Germinal Centers in Settings of De Novo Formation and Chronic Activation
Lymphatic Control of Germinal Centers in Settings of De Novo Formation and Chronic Activation
Youngnim Choi, Seoul National University
B cells Function as Innate Antigen-Presenting Cells through BCR-independent Bacterial Uptake
B cells Function as Innate Antigen-Presenting Cells through BCR-independent Bacterial Uptake
Prasanti Kotagiri, Monash University
B Cell Analysis with Multiplexed Antigen Panels Defines Determinants of Antibody Breadth in Human Vaccination and Infection
B Cell Analysis with Multiplexed Antigen Panels Defines Determinants of Antibody Breadth in Human Vaccination and Infection
Seren Baygün, DKFZ (DKTK) & Technical University Munich
Hyperreactive B Cell-Induced T Cell Control Regulates Autoimmunity And Lymphomagenesis
Hyperreactive B Cell-Induced T Cell Control Regulates Autoimmunity And Lymphomagenesis
Susana Cheetham, The University of Alabama at Birmingham
Influenza-Specific Lung-Resident Memory B cells assist CD4 Recall Responses during Challenge Infections
Influenza-Specific Lung-Resident Memory B cells assist CD4 Recall Responses during Challenge Infections
Amalie Grenov, Francis Crick Institute
Autoantibody Origins in Lupus and in Relapse Post CAR-T Therapy
Autoantibody Origins in Lupus and in Relapse Post CAR-T Therapy
Natalia Freund, Tel Aviv University
Potent Neutralization by Antibodies Targeting the Mpox virus
Potent Neutralization by Antibodies Targeting the Mpox virus
Coffee Available
4:30–5:00 PM
Canonical B Cell Immune Responses
5:00–7:00 PM
Jason G Cyster, HHMI/University of California, San Francisco
Guidance Factors and the B Cell Response
Guidance Factors and the B Cell Response
Teddy Yewdell, Genentech
Dysregulated Antibody Class Switching in Autoimmunity
Dysregulated Antibody Class Switching in Autoimmunity
Brian J Laidlaw, Washington University in St. Louis
Establishment of Lung-Resident Memory B Cells
Establishment of Lung-Resident Memory B Cells
Julia Merkenschlager, Harvard
Short Talk: Coupled Affinity Dynamics Between T Follicular Helper Cells and B Cells in the Germinal Cente
Short Talk: Coupled Affinity Dynamics Between T Follicular Helper Cells and B Cells in the Germinal Cente
Vipul Shukla, Northwestern University
Short Talk: Metabolic and Epigenetic Control Of Germinal Center B Cell Responses
Short Talk: Metabolic and Epigenetic Control Of Germinal Center B Cell Responses
Social Hour with Dinner
7:00–8:00 PM
Poster Session 1
7:30–10:00 PM
Wednesday, March 18, 2026
Breakfast
7:00–8:00 AM
Humoral Immunity in Mucosal Tissues
8:00–11:00 AM
Stephanie C. Eisenbarth, Northwestern University Feinberg School of Medicine
Origins of IgA in the Gut
Origins of IgA in the Gut
Mauro N. Gaya, Centre d’Immunologie de Marseille-Luminy
B Cell Instruction to Mucosal Antigens
B Cell Instruction to Mucosal Antigens
Jagan R. Muppidi, NCI, National Institutes of Health
Tissue Specific Cues in the Pathogenesis of Germinal Center-Derived Malignancy
Tissue Specific Cues in the Pathogenesis of Germinal Center-Derived Malignancy
Maria A. Curotto de Lafaille, Icahn School of Medicine at Mount Sinai
IgE Responses
IgE Responses
Danika L Hill, Monash University
Short Talk: Sugar-Coated Or Protein-Packed? How Antigen Type Shapes The B Cell Response To Mucosal Bacterial Infection In Humans
Short Talk: Sugar-Coated Or Protein-Packed? How Antigen Type Shapes The B Cell Response To Mucosal Bacterial Infection In Humans
Jenna Guthmiller, University of Colorado SOM
Short Talk: Ectopic Germinal Centers In Human Nasal Mucosa Are Inductive Site For Local Humoral Immunity
Short Talk: Ectopic Germinal Centers In Human Nasal Mucosa Are Inductive Site For Local Humoral Immunity
Coffee Break
9:00–9:20 AM
Poster Setup
11:00–1:00 PM
On Own for Lunch
11:00–5:00 PM
Poster Viewing
1:00–10:00 PM
Panel Discussion: Defining B Cell Subsets (Joint)
1:30–3:15 PM
Frances E. Lund, University of Alabama at Birmingham
Nicole Baumgarth, Johns Hopkins Bloomberg School of Public Health
Stephanie C. Eisenbarth, Northwestern University Feinberg School of Medicine
Kim Good-Jacobson, Monash University
Jason G Cyster, HHMI/University of California, San Francisco
Mark J. Shlomchik, University of Pittsburgh School of Medicine
Ziv Shulman, Weizmann Institute
Career Roundtable (Joint)
3:30–4:30 PM
Coffee Available
4:30–5:00 PM
Humoral Helpers (Joint)
5:00–7:00 PM
Tri G Phan, Garvan Institute of Medical Research
B Cell-Macrophage Interactions in Immunity and Autoimmunity
B Cell-Macrophage Interactions in Immunity and Autoimmunity
Michelle A Linterman, Malaghan Institute of Medical Research
Instruction of Antibody Responses Over Time
Instruction of Antibody Responses Over Time
Laura M Walker, Moderna
Vaccine Induced Antibody Responses
Vaccine Induced Antibody Responses
David R Fooksman, Albert Einstein College of Medicine
Short Talk: Investigating the Rrle of CD138 and APRIL in the Plasma Cell Survival And Dynamics In The Bone Marrow Niche
Short Talk: Investigating the Rrle of CD138 and APRIL in the Plasma Cell Survival And Dynamics In The Bone Marrow Niche
Hui Hu, University of Alabama at Birmingham
Short Talk: A Novel Bidirectional Regulatory Mechanism Coordinating Systemic CXCR5– versus CXCR5+ CD4+ T Cell Differentiation
Short Talk: A Novel Bidirectional Regulatory Mechanism Coordinating Systemic CXCR5– versus CXCR5+ CD4+ T Cell Differentiation
Social Hour with Dinner
7:00–8:00 PM
Poster Session 2
7:30–10:00 PM
Thursday, March 19, 2026
Breakfast
7:00–8:00 AM
B-T Cell Interactions in Complex Microenvironments (Cancer, TLS, EF)
8:00–11:00 AM
Ziv Shulman, Weizmann Institute
Germinal Centers in Atypical Locations
Germinal Centers in Atypical Locations
Tullia C. Bruno, University of Pittsburgh
Germinal Centers in Cancer Associated TLS
Germinal Centers in Cancer Associated TLS
Steven H Kleinstein, Yale School of Medicine
Computational Frameworks to Understand T-B Cell Interactions
Computational Frameworks to Understand T-B Cell Interactions
Jason Weinstein, Rutgers New Jersey Medical School
Specialized Tfh Cells Driving B Cell Differentiation
Specialized Tfh Cells Driving B Cell Differentiation
Joanna Groom, Walter and Eliza Hall Institute of Medical Research
Short Talk: Cellular and Molecular Networks Driving the Formation and Maturation of Tumor-Associated Tertiary Lymphoid Structures
Short Talk: Cellular and Molecular Networks Driving the Formation and Maturation of Tumor-Associated Tertiary Lymphoid Structures
Alice O Kamphorst, Icahn School of Medicine at Mount Sinai
Short Talk: CD4-help and B Cells are Essential for Therapeutic Efficacy of PD-1 Targeted Therapy in Liver Cancer
Short Talk: CD4-help and B Cells are Essential for Therapeutic Efficacy of PD-1 Targeted Therapy in Liver Cancer
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–5:00 PM
Symposia Spotlight 2
2:30–4:30 PM
Joe Mackie, Children's Hospital of Philadelphia
SARS-COV2 Vaccine Responses in Patients with Inborn Errors of Cytokine Signaling
SARS-COV2 Vaccine Responses in Patients with Inborn Errors of Cytokine Signaling
Ester Marina-Zarate, La Jolla Institute for Immunology
Highly Functional and Prolonged Germinal Center T Follicular Helper Cell Responses Are Associated with Enhanced Neutralizing Antibody Development
Highly Functional and Prolonged Germinal Center T Follicular Helper Cell Responses Are Associated with Enhanced Neutralizing Antibody Development
Dudley McNitt, Vanderbilt University Medical Center
T-B Lymphocyte Interactions Mediated by SLAM-Associated Protein (SAP) are Essential for Diabetes in Transgenic Anti-Insulin VH125SD.NOD Mice
T-B Lymphocyte Interactions Mediated by SLAM-Associated Protein (SAP) are Essential for Diabetes in Transgenic Anti-Insulin VH125SD.NOD Mice
Suzanna Rachimi, University of Pennsylvania
Determinants of Fate Progression Beyond the Human Tfh cell Stage
Determinants of Fate Progression Beyond the Human Tfh cell Stage
Hiroyuki Yoshitomi, Kyoto University
Peripheral Helper T Cells Go Beyond B-Cell Help In The Microenvironments Of Rheumatoid Arthritis
Peripheral Helper T Cells Go Beyond B-Cell Help In The Microenvironments Of Rheumatoid Arthritis
Scott Hale, University of Utah
Dnmt3a-dependent De Novo DNA Methylation Enforces Lineage Commitment and Preserves Functionality of Memory Th1 and Tfh Cells
Dnmt3a-dependent De Novo DNA Methylation Enforces Lineage Commitment and Preserves Functionality of Memory Th1 and Tfh Cells
Junko Sawada, Johns Hopkins All Children's Hospital
Inducing Tertiary Lymphoid Structures: Insights into Potential Stromal Reprogramming
Inducing Tertiary Lymphoid Structures: Insights into Potential Stromal Reprogramming
Coffee Available
4:30–5:00 PM
Non-Canonical B Cell Immune Responses
5:00–6:45 PM
Patrick Wilson, Weill Cornell Medicine
Talk Title to be Announced
Talk Title to be Announced
Ian A Cockburn, Australian National University
Regulation of B Cell Responses in Complex Infections
Regulation of B Cell Responses in Complex Infections
Mark J. Shlomchik, University of Pittsburgh School of Medicine
B Cells in Autoimmunity
B Cells in Autoimmunity
Christopher D C Allen, University of California, San Francisco
Short Talk: Regulation of IgE Switching by BCR Signaling and Cytokines
Short Talk: Regulation of IgE Switching by BCR Signaling and Cytokines
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Social Hour with Dinner
7:00–8:00 PM
Cash Bar
8:00–11:00 PM
Entertainment
8:00–11:00 PM
Friday, March 20, 2026
Departure
12:00–11:59 PM
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