Joint with: HIV Vaccines: Intersections of Basic and Clinical Science
Decoding HIV Persistence: Strategies for Curing HIV Infection

Apr 16–19, 2026 | Beaver Run Conference Center, Breckenridge, CO, United States
Scientific Organizers: Mathias Lichterfeld, Afam Okoye, Marina F. Caskey, and Caroline T. Tiemessen

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Apr 16–19, 2026 | Beaver Run Conference Center, Breckenridge, CO, United States

Scientific Organizers: Mathias Lichterfeld, Afam Okoye, Marina F. Caskey, and Caroline T. Tiemessen

Supported by:

***Meeting program subject to change.

Available Formats:     = Livestream   = In Person     = On Demand
Thursday, April 16, 2026
Registration
4:00–8:00 PM
Welcome Mixer
6:00–8:00 PM
Friday, April 17, 2026
Breakfast
7:00–8:00 AM
Welcome and Keynote Address (Joint)
8:00–9:00 AM
Alexandra Trkola, University of Zürich
HIV Vaccines: Learning from the Swiss X-BNAb Cohort for Prevention and Cure
Immune Interventions Interfacing HIV Prevention and Cure (Joint)
9:00–11:15 AM
Mauricio A. Martins, University of Florida
Promoting Persistent bNAb Expression in NHPs through AAV-Mediated Gene Transfer
Devi SenGupta, Gilead Sciences, Inc.
Long-acting ART in HIV Prevention and Cure
Leonidas Stamatatos, Fred Hutchinson Cancer Research Center
Vaccination of PLWH, using 426C Derived Immunogens
Short Talk(s) Chosen from Abstracts
Coffee Break
9:30–9:50 AM
Poster Setup
11:15–1:00 PM
On Own for Lunch
11:15–5:00 PM
Poster Viewing
1:00–10:00 PM
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Immune Targeting of HIV-1 Reservoir Cells: Obstacles and Opportunities
5:00–7:00 PM
Brad Jones, Weill Cornell Medicine
HIV Reservoir Cell Resistance to Immune-Mediated Killing
Michel C. Nussenzweig, HHMI/Rockefeller University
HIV-1 Reservoir Dynamics
Kiera L. Clayton, University of Massachusetts Medical School
NK Cell Targeting of the HIV Reservoir
Short Talk(s) Chosen from Abstracts
Social Hour with Dinner
7:00–8:00 PM
Posters
7:30–10:00 PM
Saturday, April 18, 2026
Breakfast
7:00–8:00 AM
Tailoring Gene- and Cell-Therapy Approaches for HIV Cure: Promises and Pitfalls
8:00–11:00 AM
Afam Okoye, Oregon Health & Science University
Optimizing T Cell Responses for Post-ART Control
James L. Riley, University of Pennsylvania
Immune-Based Cell Therapies
Lydie Trautmann, Military HIV Research Program
Therapeutic Vaccine Trials in Humans
Daniel Dornbusch, Excision Bio Inc.
CRISPR for HIV Cure: Human Clinical Trial Data
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
Poster Setup
11:00–1:00 PM
On Own for Lunch
11:00–5:00 PM
Poster Viewing
1:00–10:00 PM
Panel: Perspectives: Personalized Medicine & Patient-Centered Strategies (Joint)
1:30–2:45 PM
Career Roundtable (Joint)
3:00–4:30 PM
Coffee Available
4:30–5:00 PM
Mechanisms of HIV Persistence: Insights and Innovations
5:00–7:00 PM
Mathias Lichterfeld, Brigham and Women's Hospital
Epigenetic Mechanisms of HIV Persistence
Roy Matkovic, Université de Paris, Institut Cochin
The HUSH Complex and HIV Silencing
Nomonde Bengu, Umkhuseli Innovations
Sex Differences in HIV Reservoir Cell Persistence
Short Talk(s) Chosen from Abstracts
Social Hour with Dinner
7:00–8:00 PM
Posters
7:30–10:00 PM
Sunday, April 19, 2026
Breakfast
7:00–8:00 AM
No One Left Behind: HIV Cure Research Across the Age Continuum
8:00–11:00 AM
Caroline T. Tiemessen, National Institute for Communicable Diseases
HIV Immune Responses Across the Age Spectrum
Deborah Persaud, Johns Hopkins University School of Medicine
HIV Remission in Infants
Roger Shapiro, Harvard School of Public Health
Triple Combinations of Broadly-Neutralizing Antibodies in Children
Catherine K. Koofhethile, Botswana Harvard Health Partnership
Viral Reservoirs and Immune Responses in Adolescents and Young Adults with HIV
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–5:00 PM
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
B Cell Responses and Broadly-Neutralizing Antibodies: Trials and Tribulations (Joint)
5:00–6:45 PM
Marina F. Caskey, Rockefeller University
Combined Immunotherapy with IL-15 Agonists and Broadly-Neutralizing Antibodies
Paula M. Cannon, University of Southern California, Keck School of Medicine
Engineering B Cells as in vivo bnAb Factories
William Schief, The Scripps Research and IAVI
Combining Germline Targeting Approaches Across Diverse bNAb Epitopes
Short Talk(s) Chosen from Abstracts
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Social Hour with Dinner
7:00–8:00 PM
Entertainment
8:00–11:00 PM
Cash Bar
8:00–11:00 PM
Monday, April 20, 2026
Departure
12:00–11:59 PM

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