Human Microbiome: Diversity, Selection and Adaptation
Feb 18–21, 2025 | Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers:
Suzanne Devkota, Jeff F Miller and Roberto G. Kolter
In Person
On Demand
Feb 18–21, 2025 | Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers:
Suzanne Devkota, Jeff F Miller and Roberto G. Kolter
Available Formats:
Supported by the Directors' Fund
In Person
On Demand
***Meeting program subject to change.
Available Formats: = In Person = On DemandMerchandise Options
Registration Options
Tuesday, February 18, 2025
Fundraising
Booking Function
Registration
4:00–8:00 PM
Van Horne Foyer
Welcome Mixer
6:00–8:00 PM
Van Horne Foyer
Wednesday, February 19, 2025
Breakfast
7:00–8:00 AM
President's Hall
Welcome and Keynote Address (Joint)
8:00–9:00 AM
Van Horne A
* Suzanne Devkota, Cedars-Sinai Medical Center
Session Chair
Session Chair
* Bana Jabri, University of Chicago
Session Chair
Session Chair
Dan R. Littman, HHMI/New York University School of Medicine
Commensals and Pathobionts in the Gut
Commensals and Pathobionts in the Gut
Coffee Break
9:00–9:30 AM
Van Horne Foyer
Microbes Across Space, Time, and Populations
9:30–11:30 AM
Van Horne A
* Jeff F Miller, University of California, Los Angeles
Session Chair
Session Chair
Roberto G. Kolter, Harvard Medical School
The History of Microbiology and Modern-Day Approaches
The History of Microbiology and Modern-Day Approaches
Mohamed S. Abou Donia, Princeton University
Microbiome-Derived Small Molecules in Health and Disease
Microbiome-Derived Small Molecules in Health and Disease
Ashlee M Earl, Broad Institute
Genomic Insights into the Global Spread of Antibiotic Resistance
Genomic Insights into the Global Spread of Antibiotic Resistance
Moran Yassour, Hebrew University of Jerusalem
Short Talk: Revealing Hidden Diversity in Bifidobacterium Longum: Insights from Early Life Cohorts
Short Talk: Revealing Hidden Diversity in Bifidobacterium Longum: Insights from Early Life Cohorts
Orlando DeLeon, University of Chicago
Short Talk: Small and Large Bowel Microbiota Mismatches Following Fecal Microbiota Transplantation Lead to Long-Term, Unintended Effects On The Host
Short Talk: Small and Large Bowel Microbiota Mismatches Following Fecal Microbiota Transplantation Lead to Long-Term, Unintended Effects On The Host
Poster Setup
11:30–1:00 PM
Van Horne C
On Own for Lunch
11:30–2:30 PM
Poster Viewing
1:00–10:00 PM
Van Horne C
Symposia Spotlight: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Van Horne A
* Ben E Rubin, UC Berkeley
Session Chair
Session Chair
Julian Garneau, University of Lausanne
Phage-Derived Lysins for Precision Engineering of the Small Intestinal Microbiota
Phage-Derived Lysins for Precision Engineering of the Small Intestinal Microbiota
Simon Gray, University of North Carolina at Chapel Hill
Human Microbiota-Associated Mice: Mouse-Adapted Human IBD Microbiota Transplant to Colitis-Susceptible Germ-Free Mice Induces More Consistent, Reproducible Colitis with High Microbial Transfer Efficiency Relative to Human Fecal Transplant
Human Microbiota-Associated Mice: Mouse-Adapted Human IBD Microbiota Transplant to Colitis-Susceptible Germ-Free Mice Induces More Consistent, Reproducible Colitis with High Microbial Transfer Efficiency Relative to Human Fecal Transplant
Jigyasa Arora, University of California, Berkeley
Phage-Derived Protein Delivery: A Tool for Microbiome Interactions
Phage-Derived Protein Delivery: A Tool for Microbiome Interactions
Dinh Quan Nhan, Cedars-Sinai Medical Center
Identification of a Type VII Toxin Secretion System in Crohn’s Disease patient-derived Clostridium innocuum
Identification of a Type VII Toxin Secretion System in Crohn’s Disease patient-derived Clostridium innocuum
Jee-Yon Lee, University of California at Davis
Host-Derived Electron Acceptors Facilitate Uremic Toxin Production by E. coli, Exacerbating Chronic Kidney Disease
Host-Derived Electron Acceptors Facilitate Uremic Toxin Production by E. coli, Exacerbating Chronic Kidney Disease
Alex Rodriguez-Palacios, Case Western Reserve University School of Medicine
Genetically Uniform Parabacteroides from Fistulous Microlesions Highlights Lineage Adaptation in a Transmissible Bacterial-Succinate Cytotoxic Model of Crohn’s Disease Complications
Genetically Uniform Parabacteroides from Fistulous Microlesions Highlights Lineage Adaptation in a Transmissible Bacterial-Succinate Cytotoxic Model of Crohn’s Disease Complications
Nora Pyenson, NYU
Diverse Phage Communities are Maintained Stably on A Clonal Bacterial Host
Diverse Phage Communities are Maintained Stably on A Clonal Bacterial Host
Maximilian Baumgartner, CeMM GmbH
Epimerization of Host-Derived Bile Acids By Ruminococcus Gnavus as Hallmark of Microbiota Dysbiosis
Epimerization of Host-Derived Bile Acids By Ruminococcus Gnavus as Hallmark of Microbiota Dysbiosis
Coffee Available
4:30–5:00 PM
Van Horne Foyer
Microbial Diversity and Fitness
5:00–7:00 PM
Van Horne A
* Roberto G. Kolter, Harvard Medical School
Session Chair
Session Chair
Jeff F Miller, University of California, Los Angeles
Diversity Generating Retroelements in the Gut Microbiome
Diversity Generating Retroelements in the Gut Microbiome
Maria Mercedes Zambrano, Corporación CorpoGen
Community Adaptations Across Environments
Community Adaptations Across Environments
Suzanne Devkota, Cedars-Sinai Medical Center
Host-Microbe Dynamics in Inflammatory Bowel Diseases
Host-Microbe Dynamics in Inflammatory Bowel Diseases
Christopher Mancuso, MIT
Short Talk: Intraspecies Warfare Restricts Strain Coexistence In Human Skin Microbiomes
Short Talk: Intraspecies Warfare Restricts Strain Coexistence In Human Skin Microbiomes
Ming Liu, University of Oxford
Short Talk: How Does Diversity Affect Ecological Stability?
Short Talk: How Does Diversity Affect Ecological Stability?
Social Hour with Lite Bites
7:00–8:00 PM
President's Hall
Poster Session 1
7:30–10:00 PM
Van Horne C
Thursday, February 20, 2025
Breakfast
7:00–8:00 AM
President's Hall
What is a Pathobiont? Microbial Adaptations and Host Damage (Joint)
8:00–11:00 AM
Van Horne A
Peter J Turnbaugh, University of California, San Francisco
Harnessing the Gut Microbiome to Counteract and Predict Cancer Chemotherapy Toxicity
Harnessing the Gut Microbiome to Counteract and Predict Cancer Chemotherapy Toxicity
Purna C Kashyap, Mayo Clinic
Time to Turn the Spotlight on the Small Intestinal Microbiome
Time to Turn the Spotlight on the Small Intestinal Microbiome
* Russell E Vance, University of California, Berkeley
At First Sight: How Hosts and Microbes Sense Each Other
At First Sight: How Hosts and Microbes Sense Each Other
Iliyan D Iliev, Weill-Cornell Medical College
Fungal Commensalism and the Co-evolution of Type 2 Immunity
Fungal Commensalism and the Co-evolution of Type 2 Immunity
Darryl A Abbott, University of Pittsburgh
Short Talk: Maternal Immunoglobulin a Regulates the Development of the Neonatal Microbiota and Intestinal Microbiota-Specific CD4+ T Cell Responses
Short Talk: Maternal Immunoglobulin a Regulates the Development of the Neonatal Microbiota and Intestinal Microbiota-Specific CD4+ T Cell Responses
Darian T Carroll, Vanderbilt University Medical Center
Short Talk: Regulation of Enterocyte Lipid Metabolism by the Microbiota-derived Metabolite, Phenyllactic Acid
Short Talk: Regulation of Enterocyte Lipid Metabolism by the Microbiota-derived Metabolite, Phenyllactic Acid
Coffee Break
9:00–9:20 AM
Van Horne Foyer
Award Recipient Acknowledgement
9:20–9:25 AM
Van Horne A
Poster Setup
11:00–1:00 PM
Van Horne C
On Own for Lunch
11:00–2:45 PM
Career Roundtable (Joint)
1:00–2:30 PM
Van Horne B
Ashlee M Earl, Broad Institute
Director, Bacterial Genomics
Director, Bacterial Genomics
Trevor Lawley, Microbiotica/Wellcome Sanger Institute
Founder & CSO/Group Leader
Founder & CSO/Group Leader
Marin Vulic, Seres Therapeutics
Senior Principal Scientist
Senior Principal Scientist
Alex Rodriguez-Palacios, Case Western Reserve University School of Medicine
Assistant Professor
Assistant Professor
Jessica Langer, Helmsley Charitable Trust
Program Officer
Program Officer
Poster Viewing
1:00–10:00 PM
Van Horne C
Panel Discussion 1: Toward Molecular Mechanisms in Microbiome Research: Insights from Genetic Systems and Co-Evolved Pathways (Joint)
2:45–4:30 PM
Van Horne A
Ramnik Xavier, Massachusetts General Hospital
Panel Co-Leader
Panel Co-Leader
Ami S. Bhatt, Stanford University
Panel Co-Leader
Panel Co-Leader
Suzanne Devkota, Cedars-Sinai Medical Center
Andrew L Goodman, Yale School of Medicine
Michael A. Fischbach, Stanford University
George Kassiotis, The Francis Crick Institute
Coffee Available
4:30–5:00 PM
Van Horne Foyer
Jessica Langer, Helmsley Trust Introduction
5:00–5:05 PM
Van Horne A
Host Colonization and Co-Evolution of Host-Microbial Interactions (Joint)
5:05–7:00 PM
Van Horne A
Maria Manuel Dias da Mota, GIMM- Gulbenkian Institute For Molecular Medicine
Inter-Kingdom Interactions Shaping Malaria Infections
Inter-Kingdom Interactions Shaping Malaria Infections
Andrew L Goodman, Yale School of Medicine
Bacterial Diversity and Host Response to Medications
Bacterial Diversity and Host Response to Medications
* Melanie Blokesch, École Polytechnique Fédérale de Lausanne
Environmental Lifestyle and Evolvability of Vibrio Cholerae
Environmental Lifestyle and Evolvability of Vibrio Cholerae
Clarissa Campbell, The Research Center for Molecular Medicine of the Austrian Academy of Sciences (CeMM)
Short Talk: Bacterial Quorum Sensing Molecules Produced Via HdtS Homologs Affect Host T Cell Immunity In The Mammalian Gut
Short Talk: Bacterial Quorum Sensing Molecules Produced Via HdtS Homologs Affect Host T Cell Immunity In The Mammalian Gut
Gregory P Donaldson, UCLA
Short Talk: Gut Microbiota Induce an Immunoglobulin A-DMBT1 Feedback Loop to Tune Epithelial Cycling and Tumor Risk
Short Talk: Gut Microbiota Induce an Immunoglobulin A-DMBT1 Feedback Loop to Tune Epithelial Cycling and Tumor Risk
Social Hour with Lite Bites
7:00–8:00 PM
President's Hall
Poster Session 2
7:30–10:00 PM
Van Horne C
Friday, February 21, 2025
Breakfast
7:00–8:00 AM
President's Hall
Genomic Insights from Big Data and Sequencing
8:00–11:00 AM
Van Horne A
Trevor Lawley, Microbiotica/Wellcome Sanger Institute
Integrating Mass Culturing and Metagenomic Analysis for Human Microbiome Translational Science
Integrating Mass Culturing and Metagenomic Analysis for Human Microbiome Translational Science
Ami S. Bhatt, Stanford University
Dissecting Microbe: Microbe and Microbe: Host Interactions using Genomics
Dissecting Microbe: Microbe and Microbe: Host Interactions using Genomics
* Katherine S. Pollard, University of California, San Francisco
Strain-Resolved Metagenome-Wide Association Studies
Strain-Resolved Metagenome-Wide Association Studies
Jordan Jensen, Harvard University
Short Talk: Dramatically Improved Viral Profiling From Metagenomes And Metatranscriptomes Using Marker Sequence Identification
Short Talk: Dramatically Improved Viral Profiling From Metagenomes And Metatranscriptomes Using Marker Sequence Identification
Menghan Liu, Columbia University
Short Talk: Tree-Of-Life Scale Genotype-Phenotype Association Reveals Conserved Gene Modules that Govern Microbial Colonization of the Mammalian Gut
Short Talk: Tree-Of-Life Scale Genotype-Phenotype Association Reveals Conserved Gene Modules that Govern Microbial Colonization of the Mammalian Gut
William Jogia, NYU Grossman School of Medicine
Short Talk: How to Quantify Microbiome Effects for Hundreds of Food Items: A Bayesian Model for High-Dimensional, Hierarchically Related Predictors
Short Talk: How to Quantify Microbiome Effects for Hundreds of Food Items: A Bayesian Model for High-Dimensional, Hierarchically Related Predictors
Melanie Schirmer, Technical University of Munich
Short Talk: Gene-Centric Metagenomic Analysis Reveals Microbiome Functional Insights into Diseases
Short Talk: Gene-Centric Metagenomic Analysis Reveals Microbiome Functional Insights into Diseases
Coffee Break
9:00–9:20 AM
Van Horne Foyer
On Own for Lunch
11:00–2:30 PM
Coffee Available
4:30–5:00 PM
Van Horne Foyer
Novel Approaches and Applications
5:00–7:00 PM
Van Horne A
Katherine Duncan, University of Newcastle
Abyssal Antibiotics – Marine Biodiscovery from the Deep Ocean
Abyssal Antibiotics – Marine Biodiscovery from the Deep Ocean
Hannah Wastyk, Interface Biosciences
Bacterial Metabolites as Drugs
Bacterial Metabolites as Drugs
Cammie Lesser, Massachusetts General Hospital
Bacterial Delivery Systems from Agents of Pathogenesis to Vectors for Novel Therapeutics
Bacterial Delivery Systems from Agents of Pathogenesis to Vectors for Novel Therapeutics
* David Bikard, Pasteur Institute and Eligo Bioscience
Genetic Perturbation of Gut Bacteria With Engineered Phage Vectors and CRISPR
Genetic Perturbation of Gut Bacteria With Engineered Phage Vectors and CRISPR
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
7:00–7:15 PM
Van Horne A
Social Hour with Lite Bites
7:15–8:15 PM
President's Hall
Entertainment
8:15–9:15 PM
Van Horne A
Saturday, February 22, 2025
Departure
12:00–11:59 PM
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