Regenerative Biology of the Female Reproductive System

Apr 10–12, 2025 | Wylie Center and Tupper Manor at Endicott College, Beverly, MA, United States
Scientific Organizers: Kara McKinley, Margherita Y Turco, Pradeep Tanwar, and Amander Clark

  In Person
  On Demand
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Apr 10–12, 2025 | Wylie Center and Tupper Manor at Endicott College, Beverly, MA, United States

Scientific Organizers: Kara McKinley, Margherita Y Turco, Pradeep Tanwar, and Amander Clark

Supported by the  Directors' Fund

***Meeting program subject to change.

Available Formats:   = In Person     = On Demand
Thursday, April 10, 2025
Registration  
4:00–8:00 PM
 Conference Center Atrium
Welcome Mixer with Lite Bites  
6:00–8:00 PM
 Conference Center Atrium
Friday, April 11, 2025
Breakfast  
7:30–8:30 AM
 Beverly Foyer
Poster Setup  
8:00–8:30 AM
 Ipswich
Poster Viewing  
8:00–5:00 PM
 Ipswich
Welcome and Keynote Address  
8:30–9:30 AM
 Beverly Room
* Kara McKinley, Harvard University
Session Chair
Teresa K. Woodruff, Michigan State University
Remote Presenter - Oncofertility: From Bench to Bedside to Babies
Regenerative Mechanisms in the Female Reproductive Tract  
9:30–11:30 AM
 Beverly Room
* Hilary Critchley, University of Edinburgh
Session Chair
Margherita Y Turco, Friedrich Miescher Institute
Unravelling the Mechanisms Underlying Epithelial Repair in the Human Endometrium using Organoids
Kara McKinley, Harvard University
Mechanisms of Post-Menstrual Regeneration in vivo
Pradeep Tanwar, University of Newcastle
Molecular Basis of Fallopian Tube Epithelial Homeostasis
Coffee Break  
10:00–10:20 AM
 Beverly Foyer
Lunch  
11:30–12:30 PM
 Newburyport
Poster Session 1  
12:00–2:30 PM
 Ipswich
Symposia Spotlight: Short Talks Chosen from Abstracts  
2:30–4:30 PM
 Beverly Room
* Andrew Kelleher, University of MIssouri
Session Chair
* Rowan Karvas, University of Colorado- Anschutz Medical Campus
Session Chair
Jason Rizo, University of Missouri-Columbia
Neonatal Uterine Organoids Reveal Insights into Epithelial Specification and Plasticity in Development and Disease.
Elisa Zhang, University of California, Davis
Uterine Injury During Diestrus Leads to Placental and Embryonic Defects in Future Pregnancies in Mice
Katie Leap, Institut Pasteur
Comparative 3D Cell Culture Models of the Mammalian Endometrium to Understand the Evolution of Uterine Function
Dhanvika Reddy Mopure, university of missouri, Columbia
Uncovering Developmental Programs in Endometrial Regeneration Using an Epithelial Ablation Model
Xiaofei Sun, Cincinnati Children's Hospital Research Foundation
Mesenchymal-To-Epithelial Transition of Perivascular Cells Contributes to Endometrial Re-Epithelialization
Bisiayo E Fashemi, Washington University in St Louis
Single-Cell Signatures of High-Grade Serous Ovarian Cancer Patient-Derived Organoids
Hilary Skalski, Michigan State University
Impact of Obesity on the Endometrium
Rachel Thayer, University of California Davis
Developing Insect Experimental Model Systems to Investigate the Female Reproductive Tract
Coffee & Snack Available  
4:30–5:00 PM
 Beverly Foyer
Mechanisms Underpinning Fertility and Infertility  
5:00–7:00 PM
 Beverly Room
* Alexander Nikitin, Cornell University
Session Chair
Amander Clark, University of California, Los Angeles
Mechanisms of Early Germ Cell Specification and Differentiation
Binyam Mogessie, Yale University
Unraveling the Molecular Origins of Egg Aneuploidies Associated with Female Reproductive Aging
Matteo A. Molè, Stanford University
Modelling Human Embryo Implantation In Vitro Using A Cell-Engineered Receptive Endometrial Scaffold
Patti Murphy, Harvard University
Short Talk: Mechanisms of Uterine Nerve Degeneration During Pregnancy
Benjamin R Barath, University of Debrecen, Faculty of Medicine
Short Talk: Characterizing Human Hofbauer Cells, Trophoblasts, and Their Interactions That Shape the Cellular Architecture and Function of the Fetal-Maternal Interface
Dinner  
7:00–8:00 PM
 Newburyport
Trivia
8:00–9:00 PM
 Newburyport
Saturday, April 12, 2025
Breakfast  
7:30–8:30 AM
 Beverly Foyer
Poster Setup  
8:00–8:30 AM
 Ipswich
Poster Viewing  
8:00–5:00 PM
 Ipswich
Dysregulated Regenerative Mechanisms Driving “Benign” Gynecologic Conditions  
8:30–11:30 AM
 Beverly Room
* Matteo A. Molè, Stanford University
Session Chair
* Elisa Zhang, University of California, Davis
Session Chair
Linda G. Griffith, Massachusetts Institute of Technology
Identification of Core Pathways Deregulated in Endometriosis using in vitro Avatars
Digna R Velez Edwards, Vanderbilt University Medical Center
Leveraging Clinical Biobanks to Identify Novel Treatments for Uterine Fibroids and Shared Genetic Architecture with Blood Pressure
Hilary Critchley, University of Edinburgh
Failures of “Wound” Repair and Endometrial Function during Abnormal Uterine Bleeding (AUB)
Laura C Bahlmann, Massachusetts Institute of Technology
Short Talk: Old Target, New Tricks: Benchmarking Next Generation c-Jun N-Terminal Kinase (JNK) Inhibitors Using In Vitro Models Toward The Treatment Of Endometriosis
Rowan Karvas, University of Colorado- Anschutz Medical Campus
Short Talk: Blastoids as a Window into Human Trophoblast Development from Pre- to Post-Implantation Stages
Ludivine Doridot, INSERM U1016 - Université Paris Cité
Short Talk: Impact of Endometriosis on Maternal Fetal Interface Development in A Mouse Model
Michal Caspi Tal, Massachusetts Institute of Technology
Short Talk: Lyme Disease Increases Risk for Multiple Gynecological Conditions with Age
Coffee Break  
9:30–9:50 AM
 Beverly Foyer
Award Recipient Acknowledgement
9:50–9:55 AM
 Beverly Room
Lunch  
11:30–12:30 PM
 Newburyport
Poster Session 2  
12:00–2:30 PM
 Ipswich
Regenerative Biology of the Female Reproductive System: Advances and Applications  
2:30–3:30 PM
 Beverly Room
Dineo Khabele, Washington University School of Medicine
Panelist
Amander Clark, University of California, Los Angeles
Panelist
* Linda G. Griffith, Massachusetts Institute of Technology
Panelist
Coffee & Snack Available  
3:30–4:00 PM
 Beverly Foyer
Dysregulated Regenerative Mechanisms in Reproductive Cancers  
4:00–6:00 PM
 Beverly Room
* Ronald Chandler, Michigan State University
Session Chair
Diego H Castrillon, University of Texas Southwestern Medical Center
Endometrial Cancer Onset and PAX2
Cindrilla Chumduri, Aarhus University
Tissue Homeostasis of the Cervix and its Alterations in Infection and Cancer
Alexander Nikitin, Cornell University
Dysregulated Stem Cells in the Pathogenesis of Gynecological Cancers
Dineo Khabele, Washington University School of Medicine
Drivers of Chemotherapy-Resistant Ovarian Cancer
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)  
6:00–6:15 PM
 Beverly Foyer
On Own for Dinner  
6:15–8:00 PM
Transportation to Dinner Options  
6:30–10:00 PM
Sunday, April 13, 2025
Departure  
8:00–9:00 AM

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