Joint with: Obesity Causes and Consequences
Cardiometabolic Diseases: The Role of Ethnic Diversity in Precision Medicine
Feb 04–07, 2024 | Fairmont Hotel Vancouver, Vancouver, BC, Canada
Scientific Organizers:
Paul W. Franks, Ewan Pearson, and Karin Conde-Knape
In Person
On Demand
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Feb 04–07, 2024 | Fairmont Hotel Vancouver, Vancouver, BC, Canada
Scientific Organizers: Paul W. Franks, Ewan Pearson, and Karin Conde-Knape
Paul W. Franks
Ewan Pearson
Karin Conde-Knape
Available Formats:
Supported by the Directors' Fund
In Person
On Demand
***Meeting program subject to change.
Available Formats: = In Person = On DemandBooking Function
Fundraising
Merchandise Options
Registration Options
Sunday, February 4, 2024
Arrival and Registration
4:00–8:00 PM
British/Columbia Foyer
Welcome Mixer
6:00–8:00 PM
British/Columbia Foyer
Monday, February 5, 2024
Breakfast
7:00–8:00 AM
Pacific Ballroom, Vancouver Island Room
Welcome and Keynote Session (Joint)
8:00–9:30 AM
Columbia Ballroom
* Giles S.H. Yeo, University of Cambridge
Session Chair
Session Chair
* Ewan Pearson, University of Dundee
Session Chair
Session Chair
Stephen O'Rahilly, University of Cambridge
Leveraging Genetics to Understand Metabolic Disease
Leveraging Genetics to Understand Metabolic Disease
Jose C. Florez, Massachusetts General Hospital
Optimising Precision Medicine Across Diverse Ethnicities
Optimising Precision Medicine Across Diverse Ethnicities
Coffee Break
9:30–9:50 AM
British/Columbia Foyer
Genetics of Obesity (Joint)
9:50–11:15 AM
Columbia Ballroom
* Andrea M. Haqq, University of Alberta
Session Chair
Session Chair
Kaja Wasik, Variant Bio
Metabolic Disease in the Context of Genetic Diversity
Metabolic Disease in the Context of Genetic Diversity
Peter R. Shepherd, University of Auckland
Population Specific Precision Medicine for Metabolic Disease
Population Specific Precision Medicine for Metabolic Disease
Kathrin Landgraf, Center for Pediatric Research, Hospital for Children and Adolescents, Medical Faculty, University of Leipzig
Short Talk: Short Talk: Ectopic ASIP Expression as a Monogenic cause of Childhood Obesity through Possible Interaction with the MC4R Pathway
Short Talk: Short Talk: Ectopic ASIP Expression as a Monogenic cause of Childhood Obesity through Possible Interaction with the MC4R Pathway
Yana Hrytsenko, Beth Israel Deaconess Medical Center, Harvard Medical School
Short Talk: Short Talk: Obstructive Sleep Apnea is Associated with Increased Genetic Risk of Incident Diabetes Mellitus: the Hispanic Community Health Study/Study of Latinos
Short Talk: Short Talk: Obstructive Sleep Apnea is Associated with Increased Genetic Risk of Incident Diabetes Mellitus: the Hispanic Community Health Study/Study of Latinos
Poster Setup
11:15–1:00 PM
Pacific Ballroom, Vancouver Island Room
On Own for Lunch
11:15–5:00 PM
Poster Viewing
1:00–10:00 PM
Pacific Ballroom, Vancouver Island Room
Workshop
2:30–4:30 PM
British Ballroom
* Karin Conde-Knape, Novo Nordisk A/S
Session Chair
Session Chair
Reka Nagy, Novo Nordisk Research Centre Oxford
Identification of South-Asian Ancestry-Specific Genetic Risk Factors for Cardiometabolic Disease
Identification of South-Asian Ancestry-Specific Genetic Risk Factors for Cardiometabolic Disease
Claire Wang, University of Auckland
Understanding Genetic Impact on Metformin Efficacy to Guide Clinical Treatment in Diabetes
Understanding Genetic Impact on Metformin Efficacy to Guide Clinical Treatment in Diabetes
Arjana Begzati, University of California, San Diego
Racial Differences in Metabolite Predictors of Type 2 Diabetes Risk
Racial Differences in Metabolite Predictors of Type 2 Diabetes Risk
Madeleine ME Hayman, University of Glasgow, University of Edinburgh
GLP1R locus: a Connection Between Mental Ill-Health and Cardiometabolic Disease?
GLP1R locus: a Connection Between Mental Ill-Health and Cardiometabolic Disease?
Absalon Gutierrez, The University of Texas Health Science Center at Houston
Pharmacogenetics of the Response to GLP-1 in Mexican-Americans with Prediabetes: A Preliminary Analysis
Pharmacogenetics of the Response to GLP-1 in Mexican-Americans with Prediabetes: A Preliminary Analysis
Fannie Lajeunesse-Trempe, Université Laval
Adiposity Phenotypes and Associated Cardiometabolic Risk Profile Among the Inuit Population of Nunavik
Adiposity Phenotypes and Associated Cardiometabolic Risk Profile Among the Inuit Population of Nunavik
Elizabeth Godschall, University of Virginia
Development of Humanized Glp-1 Receptor Mouse to Investigate the Small Molecule Agonist Mechanism of Action
Development of Humanized Glp-1 Receptor Mouse to Investigate the Small Molecule Agonist Mechanism of Action
Coffee Available
4:30–5:00 PM
British/Columbia Foyer
Environmental Diversity Within and Between Populations
5:00–7:00 PM
British Ballroom
* Viswanathan Mohan, Madras Diabetes Research Foundation & Dr. Mohan's Diabetes Specialities Centre
Session Chair
Session Chair
John Chambers, Nanyang Technological University
Epigenetic Drivers of CMD in South Asians
Epigenetic Drivers of CMD in South Asians
Karin Conde-Knape, Novo Nordisk A/S
How can we Ensure Precision Medicines are Efficacious and Safe Across Diverse Ethnicities?
How can we Ensure Precision Medicines are Efficacious and Safe Across Diverse Ethnicities?
Chirag J. Patel, Harvard Medical School
Assessing the Genetic Contribution of Behaviors and Exposures Associated with Longitudinal Type 2 Diabetes Highlights the Adiposity and the Brain-metabolic Axis
Assessing the Genetic Contribution of Behaviors and Exposures Associated with Longitudinal Type 2 Diabetes Highlights the Adiposity and the Brain-metabolic Axis
Social Hour with Lite Bites
7:00–8:00 PM
Pacific Ballroom, Vancouver Island Room
Poster Session 1
7:30–10:00 PM
Pacific Ballroom, Vancouver Island Room
Tuesday, February 6, 2024
Breakfast
7:00–8:00 AM
Pacific Ballroom, Vancouver Island Room
Diversity in Pathophysiological Drivers of CMD
8:00–11:00 AM
British Ballroom
* Moneeza Siddiqui, Queen Mary University of London
Session Chair
Session Chair
Paul W. Franks, Lund University and Novo Nordisk Foundation
Remote Presentation: Next-Generation Epidemiology, Ethnic Diversity and Cardiometabolic Disease
Remote Presentation: Next-Generation Epidemiology, Ethnic Diversity and Cardiometabolic Disease
Shivani Misra, Imperial College London
Ethnic Diversity and Cardiometabolic Disease in Young People
Ethnic Diversity and Cardiometabolic Disease in Young People
Ewan Pearson, University of Dundee
Ethnicity, Phenotype and Precision Diabetes Care
Ethnicity, Phenotype and Precision Diabetes Care
Alan James Davidson, University of Auckland
Short Talk: Short Talk: A Gene Variant in CALCRL, Encoding a G-Protein Coupled Receptor, is Highly Enriched in Individuals with Māori and Pacific Ancestry and Associates with a Higher Risk of Kidney Failure in Diabetes
Short Talk: Short Talk: A Gene Variant in CALCRL, Encoding a G-Protein Coupled Receptor, is Highly Enriched in Individuals with Māori and Pacific Ancestry and Associates with a Higher Risk of Kidney Failure in Diabetes
Andreas L Birkenfeld, Helmholtz Munich
Short Talk: Short Talk: Precision Remission of Prediabetes within High-Risk Prediabetes Clusters
Short Talk: Short Talk: Precision Remission of Prediabetes within High-Risk Prediabetes Clusters
Coffee Break
9:00–9:20 AM
British/Columbia Foyer
Poster Setup
11:00–1:00 PM
Pacific Ballroom, Vancouver Island Room
On Own for Lunch
11:00–5:00 PM
Health Equity Forum (Joint)
11:30–1:00 PM
Columbia Ballroom
Kaja Wasik, Variant Bio
Panelist
Panelist
Peter R. Shepherd, University of Auckland
Panelist
Panelist
Moneeza Siddiqui, Queen Mary University of London
Panelist
Panelist
Shivani Misra, Imperial College London
Panelist
Panelist
Moffat Nyirenda, London School of Hygiene and Tropical Medicine
Panelist
Panelist
Poster Viewing
1:00–10:00 PM
Pacific Ballroom, Vancouver Island Room
Coffee Available
4:30–5:00 PM
British/Columbia Foyer
Delivering Precision Medicine in Low-Middle Income Settings
5:00–7:00 PM
British Ballroom
* Ewan Pearson, University of Dundee
Session Chair
Session Chair
Moffat Nyirenda, London School of Hygiene and Tropical Medicine
Optimising the Prevention and Treatment of CMD when Infectious Disease is Highly Prevalent
Optimising the Prevention and Treatment of CMD when Infectious Disease is Highly Prevalent
John Dennis, University of Exeter Medical School
Parsimonious Strategies for Precision Medicine in Practice - Lessons from the TriMaster Trial
Parsimonious Strategies for Precision Medicine in Practice - Lessons from the TriMaster Trial
Viswanathan Mohan, Madras Diabetes Research Foundation & Dr. Mohan's Diabetes Specialities Centre
Barriers and Possibilities when Delivering Precision Medicine in Resource Constrained Settings: Indian Experience
Barriers and Possibilities when Delivering Precision Medicine in Resource Constrained Settings: Indian Experience
Kristina M Garske, Princeton University
Short Talk: Short Talk: Detecting Decoherent Gene Co-Expression Patterns Associated with a Rural-to-Urban Lifestyle Transition in Turkana
Short Talk: Short Talk: Detecting Decoherent Gene Co-Expression Patterns Associated with a Rural-to-Urban Lifestyle Transition in Turkana
Alisa Manning, Massachusetts General Hospital
Short Talk: Short Talk: Proteins Associated with Self-Report Race/Ethnicity Partially Mediate the Association with Type 2 Diabetes. A Meta-Analysis of 2,339 Individuals From Two Multi-Ethnic Cohorts
Short Talk: Short Talk: Proteins Associated with Self-Report Race/Ethnicity Partially Mediate the Association with Type 2 Diabetes. A Meta-Analysis of 2,339 Individuals From Two Multi-Ethnic Cohorts
William L. Holland, University of Utah
Short Talk: Short Talk: Identification and Characterization of a Novel Variant in Neutral Ceramidase Associated with Diabetes and Kidney Failure in Tongan and Samoan Patients
Short Talk: Short Talk: Identification and Characterization of a Novel Variant in Neutral Ceramidase Associated with Diabetes and Kidney Failure in Tongan and Samoan Patients
Social Hour with Lite Bites
7:00–8:00 PM
Pacific Ballroom, Vancouver Island Room
Poster Session 2
7:30–10:00 PM
Pacific Ballroom, Vancouver Island Room
Wednesday, February 7, 2024
Breakfast
7:00–8:00 AM
Pacific Ballroom, Vancouver Island Room
Precision Obesity Management (Joint)
8:00–11:00 AM
Columbia Ballroom
* Abd A Tahrani, Novo Nordisk
Session Chair
Session Chair
Karine Clément, INSERM / Sorbonne Universite
Precision Obesity Medicine in Practice
Precision Obesity Medicine in Practice
Daniel J. Drucker, Lunenfeld-Tanenbaum Research Institute
The GLP1/GIP System in Obesity Management
The GLP1/GIP System in Obesity Management
Moneeza Siddiqui, Queen Mary University of London
Insights From Genetic and Observational Studies in South Asian Populations
Insights From Genetic and Observational Studies in South Asian Populations
Sarah Berry, King's College London
Personalised Nutrition in Obesity Management
Personalised Nutrition in Obesity Management
Jordan B. Wean, University of Michigan
Short Talk: Short Talk: GABAergic GIPR-expressing Neurons are Required for the Body Weight Reduction caused by Dual Incretin Agonists
Short Talk: Short Talk: GABAergic GIPR-expressing Neurons are Required for the Body Weight Reduction caused by Dual Incretin Agonists
Coffee Break
9:00–9:20 AM
British/Columbia Foyer
On Own for Lunch
11:00–5:00 PM
Career Roundtable (Joint)
3:00–4:30 PM
British Ballroom
Jose C. Florez, Massachusetts General Hospital
Physician-in-Chief, Chair, and Professor
Physician-in-Chief, Chair, and Professor
Leslie J. Baier, National Institutes of Health
Section Chief: Diabetes Molecular Genetics Section
Section Chief: Diabetes Molecular Genetics Section
Kyle Kai-How Farh, Illumina
VP & Distinguished Scientist
VP & Distinguished Scientist
Sarah Berry, King's College London
Reader & Associate Professor
Reader & Associate Professor
Coffee Available
4:30–5:00 PM
British/Columbia Foyer
Genetic and Non-Genetic Biological Diversity Across Diverse Ethnicities
5:00–6:45 PM
British Ballroom
* John Chambers, Nanyang Technological University
Session Chair
Session Chair
Kyle Kai-How Farh, Illumina
Artificial Intelligence for Precision Medicine and Drug Target Discovery
Artificial Intelligence for Precision Medicine and Drug Target Discovery
Leslie J. Baier, National Institutes of Health
Understanding the Heritable basis of Obesity and Type 2 Diabetes Among Indigenous People Living in Southwestern United States
Understanding the Heritable basis of Obesity and Type 2 Diabetes Among Indigenous People Living in Southwestern United States
Megan P Leask, University of Alabama at Birmingham
Short Talk: Short Talk: GWAS And Beyond: Cardiometabolic Variant Discovery For Māori And Pacific People
Short Talk: Short Talk: GWAS And Beyond: Cardiometabolic Variant Discovery For Māori And Pacific People
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
British Ballroom
Social Hour with Lite Bites
7:00–8:00 PM
Pacific Ballroom, Vancouver Island Room
Cash Bar
8:00–9:00 PM
Pacific Ballroom, Vancouver Island Room
Thursday, February 8, 2024
Departure
7:00–11:59 PM
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